• Title/Summary/Keyword: 프로폴리스

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Antimicrobial Activities of Korean Propolis (국산 프로폴리스의 항균활성)

  • 이수원;황보식;김희재
    • Food Science of Animal Resources
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    • v.22 no.1
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    • pp.66-71
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    • 2002

  • As extraction solvent, ethanol fraction was revealed the highest anti-microbial activities. The butanol, ethyl acetate and chloroform fractions were also revealed anti-microbial activities with less extent compared to ethanol fraction. All fractions exhibited to inhibition of bacterial growth regardless gram positive and negative, yeast and fungi, however, was not exhibited effectively to their growth. In the inhibition activities against E. coli, the complete inhibition concentration of Yecheon propolis were at 0.40mg/ml, respectively. Complete inhibition concentration of Youngwol was revealed at 0.25mg/ml after 12 hours incubation. In the inhibition activities against P. aeruginosa, the complete inhibition concentration of Youngwol propolis wat at 0.20mg/ml. Yecheon propolis was reveraled the inhibition at 0.20mg/ml after 12 hours incubation. In the inhibition activities against S. typhimurium, the complete inhibition concentration of Youngwol propolis was at 0.20 and 0.25mg/ml and Yecheon was 0.40mg/ml. The Minimum Inhibitory Concentration (MIC) of ethanol extraction fraction of Yecheon propolis to P. aeruginosa, S. aureus, and S. typhimurium were > 0.2, 0.25, 0.25 and 0.4∼>0.5mg/ml, and of Youngwol propolis to P. aeruginosa, E. coli, S. aureus, S. typhimurium, B. subtlis and C. utilis were 0.15, 0.25, 0.25, 0.3 and 0.4mg/ml, respectively.

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UPLC Analysis of Pinocembrin and Antimicrobial Activity of Propolis Collected from Different Regions in Korea (지역별 국산 프로폴리스의 항균활성 및 Pinocembrin의 UPLC 분석)

  • Kim, Se Gun;Hong, In Pyo;Woo, Soon Ok;Jang, Hye Ri;Han, Sang Mi
    • Journal of Apiculture
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    • v.32 no.3
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    • pp.253-259
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    • 2017

  • Propolis, natural antibacterial agent, which has been used traditional medicine across the globe, is resinous mixture to include abundant bioactive substances. In present study, we investigated antimicrobial activity according to quality characteristics of propolis collected from 9 different regions in Korea. Antimicrobial activity was evaluated by measuring growth inhibition zone using agar well diffusion method against Streptococcus mutans. Constituents analysis of propolis samples were measured through total phenolic contents, total flavonoid contents and quantitative analysis of major compound (pinocembrin) by ultra performance liquid chromatography. As a result, 9 different propolis (10mg/mL) and pinocembrin (1mg/mL) showed antimicrobial activity that has growth inhibition zone more than 11.9mm on S. mutans. The total flavonoid contents of 8 different propolis excluding Jeju island were in compliance with standard of health functional food in Korea and were found to affect antimicrobial activity on S. mutans when contained over 10mg/g. In addition, when content of pinocembrin in propolis was ranged from 12mg/g to 32mg/g, each propolis excluding Jeju island exhibited antimicrobial activity alike. These results indicate that pinocembrin plays a important role for antimicrobial activity of propolis collected from 8 different regions in Korea, and that it can be used as basic data for standardization of Korean propolis.

  • https://doi.org/10.17519/apiculture.2017.09.32.3.253 인용

Changes in Lymphocyte DNA Damage and Antioxidant Status after Supplementing Propolis to Korean Smokers: A Placebo-Controlled, Double-Blind Cross-Over Trial (프로폴리스 섭취 후 흡연자의 임파구 DNA 손상도 및 항산화 상태의 변화: 이중맹검 교차 인체시험)

  • Kang, Myung-Hee;Lee, Hye-Jin;Kim, Mi-Kyung;Sung, Mi-Kyung;Kwon, O-Ran;Park, Yoo-Kyoung
    • Journal of Nutrition and Health
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    • v.42 no.5
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    • pp.442-452
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    • 2009

  • Smoking has been known to exacerbate the initiation and propagation of oxidative stresses. Efforts have been made to reduce the smoking-induced oxidative stresses using commercial dietary supplements. Propolis is the resinous substance collected by bees from the leaf buds and bark of trees, especially poplar and conifer trees. In this trial, we examined whether a daily supplementation of 800 mg propolis can protect endogenous lymphocytic DNA damage and modulate antioxidative enzyme activities and the level of antioxidant vitamin in smokers using a placebo-controlled, doubleblinded cross-over trial. After two weeks of running-in period, 29 smokers (mean age 34.38 ${\pm}$ 1.73) received 6 tablets/day of either propolis or placebo pills for 4 weeks. After 2 weeks of washout period the subjects switched they pills for cross-over study. The degree of DNA damage (assessed by tail DNA, tail length and tail moment) was not significantly changed with propolis intake or placebo intake. Similarly, total antioxidant status (TAS) remained at the same level regardless of the treatment. Erythrocyte catalase, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), plasma vitamin C and tocopherol level did not differ before and after propolis treatment, and did not differ between treatments. Putting all these results together, we would suggest that it is still too early to claim that propolis possess antioxidative activities.

  • https://doi.org/10.4163/kjn.2009.42.5.442 인용 PDF KSCI