• Title/Summary/Keyword: 표피심도

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Gamma-ray-induced skin injury in the mini-pig: Effects of irradiation exposure on cyclooxygenase-2 expression in the skin (감마선조사에 의한 돼지 피부장애에 cyclooxygenase-2의 발현변화)

  • Kim, Joong Sun;Park, Sunhoo;Jang, Won Seok;Lee, Sun Joo;Lee, Seung Sook
    • Journal of Radiation Protection and Research
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    • v.40 no.1
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    • pp.65-72
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    • 2015
  • The basic concepts of radiation-induced skin damage have been established, the biological mechanism has not been studied. In this study, we have examined the effects of gamma rays on skin injury and cyclooxygenase(COX)-2 expression. Gamma irradiation induced clinicopathological changes in a dose- and time-dependent manner in mini-pig skin. The histological changes were consistent with the changes in gross appearance at 12 weeks after irradiation. After three days' irradiation, apoptotic cells in the basal layer were found more frequently in irradiated skin than in normal skin, with the magnitude of the effect being dose-dependent. The thickness of the epidermis transiently increased 3 days after irradiation, and then gradually decreased, although changes in the epithelial thickness of the irradiated field were not observed with irradiation doses over 50 Gy. In the epithelium, there was an initial degenerative phase, during which the rate of basal cell depletion was dependent on the radiation dose (20-70 Gy). One week after irradiation, COX-2 expression was mostly limited to the basal cell layer and was scattered across these cells. High COX-2 expression was detected throughout the full depth of the skin after irradiation. The COX-2 protein is upregulated after irradiation in mini-pig skin. These histological changes associated with radiation exposure dose cause the increased COX-2 expression in a dose-dependent fashion.

Leaf epidermal microstructure of the genus Scopolia Jacq. s.l. (Solanaceae-Hyoscymeae) and its systematic significance (광의의 미치광이풀속(Scopolia Jacq. s.l., 가지과-Hyoscymeae족)의 잎표피 미세구조와 이의 계통분류학적 중요성)

  • Hong, Suk-Pyo;Paik, Jin-Hyub
    • Korean Journal of Plant Taxonomy
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    • v.31 no.3
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    • pp.267-282
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    • 2001
  • To examine the leaf epidermal microstructure of three genera (Scopolia s.s., Anisodus, AtroPanthe, including Przewalskia as an outgroup) in the genera Scopolia Jacq. s.l., leaves of 10 species (37 specimens) were investigated by the light microscopy (LM) and scanning electron microscopy (SEM). The stomata of studied taxa were 'amphistomatic type' and the size (guard cell) range was $18-64{\times}11-48{\mu}m$. The size of stomata is slightly differed from between the taxa; the smallest size of stomata were found in the monotypic genus, Przewalskia ($24-27{\times}16-17{\mu}m$), on the other hand the largest one was found in Anisodus carniolicoides ($62-64{\times}43-48{\mu}m$). The stomatal complex was mostly anomocytic (in Scopolia s.s., Anisodus taxa : A. luridus, A. carniolicoides, A. acutangulus) and sometimes anisocytic (in Anisodus tanguticus, Przewalskia, Atropanthe). The stomata is mostly crescent in shape, but rarely circular, especially in Przewalskia tangutica. The shapes of epidermal cells are similar in both adaxial and abaxial sides, and mostly undulate/sinuate polygonal anticlinal wall, but rarely arched in Przewalskia tangutica. The epicuticular wax was not well developed in most studied taxa, except Anisodus tanguticus which is well developed cuticular striae around the stomatal complex. The elongate-headed glandular trichomes were found in Scopolia s.s. and Przewalskia. While the taxa of Anisodus and Atropanthe have not any trichomes (i. e., glabrous), except Anisodus luridus, which has simple or sometimes branched (dendritic- type) non-glandular trichome. Finally, the systematic and ecological significance of the leaf micromorphological features (stomata complex, trichome, etc.) in identification and elucidation of Scopolia s.l. including Przewalskia, especially between or within the genera including among the species is also discussed.

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Expression of Growth Factors and Secretory Leukocyte Protease Inhibitor (SLPI) in RAW264.7 Cells after Lipopolysaccharide (LPS) Stimulation (대식세포주 (RAW264.7)에서 박테리아성 지질다당류 (LPS) 자극에 의한 분비백혈구단백분해효소억제제 (SLPI)와 성장인자들의 발현)

  • Son, Wook-Hee;Choi, Baik-Dong;Jeong, Soon-Jeong;Wang, Guan-Lin;Hwang, Ho-Keel;Jeong, Moon-Jin
    • Applied Microscopy
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    • v.37 no.2
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    • pp.93-102
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    • 2007
  • Secretory leukocyte protease inhibitor (SLPI) was known as one of bacterial lipopolysaccharide (LPS)-induced products of macrophage. Macrophages play an important role in the development of inflammatory responses by secreting an array of cytokines and chemokines in a tissue microenvironment. To identify the function and relationship between potent growth factors and SLPI after LPS stimulation, we conducted reverse transcriptase polymerase chain reaction (RT-PCR) and Western blots for the detection of mRNA and protein expression of SLPI and growth factors such as VEGF, PDGF, bFGF after 100 ng LPS stimulation on the RAW264.7 cells. The result of RT-PCR was showed SLPI mRNA expression was increased from 60 min to 48h in RAW 264.7 cells after incubation with LPS. VEGF and PDGF mRNA was expressed highly at initial stage by LPS stimulation. The mRNA of bFGF and type I collagen was very weakly expressed after LPS stimulation. SLPI protein level was increased likely the mRNA levels in RAW 267.7 cells. Additionally, phase contrast and scanning electron microscopic observation demonstrated that the LPS induce the change of morphology of the RAW264.7 cells. From these results, it suggest that expression of SLPI by LPS treatment may associate with VEGF and PDGF expression in RAW264.7 cells.

Rust of Iris nertschinskia Caused by Puccinia iridis (Puccinia irdis에 의한 붓꽃 녹병의 발생)

  • Kwon, Jin-Hyeuk;Park, Chang-Seok
    • Research in Plant Disease
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    • v.9 no.3
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    • pp.125-127
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    • 2003
  • Rust disease was occurred on Iris in several farmer's fields fields located in Hoehwa-myon, Goseong-gun, Gyeong-nam province in Korea. The typical symptoms of the disease appeared first as small, yellowish spot on leaves. The spots then turn brown, their edges rised slightly, and powdery mass of yellowish brown spores revealed on the lesions. Severely infected leaves were blighted and eventually died. Urediniospores were yellowish brown to reddish brown in color, obobid to obovoid in shape and 22~30 ${\times}$ 21~25${\mu}m$m in size. Teliospores were chestnet-brown in color, oblong or clavate in shape and 32~54 ${\times}$ 12~22${\mu}m$ in size. The causal fungus was identified as Puccinia iridis, based on morphological characteristics. This is the first report on the rust of Iris nertschinskia by Puccinia iridis in Korea.

Rust of Belamcanda chinensis Caused by Puccinia belamcandae (Puccinia belamcandae에 의한 범부체 녹병)

  • Kwon, Jin-Hyeuk;Park, Chang-Seuk
    • The Korean Journal of Mycology
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    • v.32 no.1
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    • pp.54-56
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    • 2004
  • Rust disease was occurred on blackberry lily (Belamcanda chinensis) in several farmer's fields located in Heohwa-myon, Goseong-gun, Gyeongnam province in Korea. The typical symptoms of the disease appeared as small, yellowish spot on leaves at first. The spots then turned brown, their edges rised slightly, and powdery mass of yellow or yellowish green spores appeared on the lesions. Severely infected leaves were blighted and eventually died. Urediniospores were yellow or yellowish brown in color, globoid to ovoid in shape and $21{\sim}46{\times}18{\sim}38\;{\mu}m$ in size. Teliospores were brown in color, oblong or clavate in shape and $32{\sim}64{\times}12{\sim}26\;{\mu}m$ in size. The causal fungus was identified as Puccinia belamcandae based on morphological characteristics and host specificity. This is the first report on the rust of B. chinensis caused by P. belamcandae in Korea.

Eyelid Squamous Cell Carcinoma in a Horse in Jeju (제주도의 말에서 발생한 안검 중층편평상피 암종)

  • Kim, Jae-Hoon;Woo, Gye-Hyeong;Kim, Jae-Hoon
    • Journal of Veterinary Clinics
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    • v.30 no.5
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    • pp.399-402
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    • 2013
  • An 8-year-old, female, mixed Thoroughbred horse was presented for the evaluation of the left upper eyelid mass with ocular discharge during 4 months. After unilateral surgery, excised eyelid mass and left eye were submitted for diagnosis. Grossly, the removed mass was $6{\times}7{\times}2$ cm in size and dome shape with rough irregular surface. On the cut surface, mass was firm and yellowish white in color. Histopathologically, severely proliferated stratified squamous epithelia were heavily invaginated into dermis, and then formed rete ridge or numerous squamous islands. These neoplastic islands were composed of multiple layers of prickle cells with intercellular bridge and central laminated keratin pearls or necrotic cellular debris. Based on the above results, this case was diagnosed as squamous cell carcinoma in upper eyelid of horse.

Effect of Low Temperature Treatment on the Bud, Bark and Growth of Kiwifruit tree (저온처리에 의한 Kiwifruit나무의 내성에 관하여)

  • Cheong, Sam Taek;Han, Kyo Phil
    • Current Research on Agriculture and Life Sciences
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    • v.11
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    • pp.25-30
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    • 1993
  • The buds of Hayward/Bruno tree were damaged from $-7^{\circ}C$ but serious damage was found on the buds treated at $-15^{\circ}C$ and $19^{\circ}C$. The bark tissue was more suceptible to low temperature than the bud. The trees were survived and bursted their at all on the top of the graft union and new shoots were formed from the rootstock of the tree. Yellowish area on the leaf surface was found, which is believed that as a result of low temperature. From these, the kiwifruit trees must be grafted with cold tolerant rootstocks will be clarified in future.

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Rust of Lysimachia clethroides Caused by Puccinia dieteliana (Puccinia dieteliana에 의한 큰까치수영녹병)

  • Kim, Seong-Hwan;Lee, Tae-Soo
    • The Korean Journal of Mycology
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    • v.36 no.2
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    • pp.196-198
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    • 2008
  • A rust disease occurred on Lysimachia clethroides in Deogyusan National Park, Jeollabukdo. The typical symptoms of the disease appeared as small, yellowish spots on leaves at first. The spots then turned yellowish brown and powdery mass of blackish brown spores appeared on the lesions. Severely infected leaves blighted and eventually shriveled. Teliospores were yellowish brown in color, clavate or fusiform in shape and $38{\sim}62\;{\times}\;14{\sim}22\;{\mu}m$ in size, the apex rounded or obtuse, the base attenuated. Pedicels hyaline, persistence, up to $75{\mu}m$ long. The causal fungus was identified as Puccinia dieteliana based on mycological characteristics and host specificity.

Three Cases of Erythema Multiforme Developed during Deflazacort Therapy in Children with Nephrotic Syndrome (소아 신증후군 환자에서 데플라자코트 치료 중 발생된 다형 홍반 3례)

  • Lee, Seung Jin;Kang, Bong Hwa;Cho, Min Hyun
    • Childhood Kidney Diseases
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    • v.18 no.2
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    • pp.123-127
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    • 2014
  • Erythema multiforme (EM) is an acute mucocutaneous disorder involving the skin, mouth, eyes, and genital organs. It is classified into EM minor and EM major according to the involvement of the mucosal membrane. Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) belong to EM major. Compared to EM minor, SJS presents with more severe and progressive symptoms, and has a higher mortality rate. Corticosteroids are used in the treatment of EM. We report three cases of EM (two cases of EM minor and one case of SJS) that developed during treatment with oral corticosteroid (deflazacort; $Calcort^{(R)}$) in children with nephrotic syndrome.

Characteristics of 'Skin Phenomenon' as Intermediate Medium of Interior and Exterior Space shown in Fashion and Interior Design (패션과 실내디자인에 나타난 내외부 연결 매체로서의 스킨개념 특성에 관한 연구)

  • Shim Eun-Ju;Cho Jong-Soo;Chu Beom
    • Korean Institute of Interior Design Journal
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    • v.15 no.4 s.57
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    • pp.29-36
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    • 2006
  • Fashion and interior architecture are two areas of design that may share common issues, trends and philosophies, making fashion design human's second skin and interior architecture the third. The concept of 'skin' has become one of the most interesting phenomena in design during the past decade and not surprisingly similar issues can be seen also in fashion and architectural design. The current trend in fashion design is that the skin (clothing) has become detached from the human body and extended into the environment, resulting fashion as art objects. Skin in architecture and interior design has also become detached from the structure so designers have more freedom to experiment by using advanced technologies. The present study attempts to analyze common features of 'skin phenomenon' in fashion and interior architecture that are; detachment, emphasis on space, extension, territorial blending, and digital applications. The researcher has used constant comparative method to categorize the five features among many examples. The limitation of this study is that it is focused on the formative phenomena of projects excluding the philosophies and personal background of each designer. However, it is hoped that the study may assist designers and other researchers to understand relationships between fashion and interior design, hold broader spectrum in art and design.