• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2015.10a
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• pp.347-349
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• 2015

마스터플랜 과정의 한 부분으로서, 관리자와 cordlawek가 되기 위한 교육프로그램 IALA WWA의 모델 과정을 기초로 한 교육에 대해 이수가 필요하다. 국제적인 협약 및 조직. 교육 참가자는 항로표지와 관련해서 IMO, IALA, SOLAS Chapter 5와 UNCLOS 82, 그리고 이 기준들을 유지하기위한 법적인 의무를 이해하는 국제 협약 및 조직과 직접적으로 친밀해져야 한다. 항해환경. 교육 참가자는 e-Navigation과 관련된 이슈들을 이해하는데 노력해야한다. 항로표지 서비스 제공의 관리. 교육 참가자는 항로표지 서비스 관리와 역사적인 항로표지 시설의 보존에 높은 경쟁력을 가져야 한다. 기술적인 이슈 워크숍. 교육 참가자는 직업에서 발생할 수 있는 기술적인 이슈에 관한 토의에 참석해야 한다.

• The Korean Journal of Cytopathology
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• v.7 no.1
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• pp.1-11
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• 1996

From the concepts of cellular pathology and of exfoliative cytology, as elucidated by Virchow and Papanicolaou respectively in the late 19th and early 20th century, have evolved the primary methods for the diagnosis of cancer today. From Papanicolaou's concept of exfoliative cytology developed fine needle aspiration biopsy in the early 1960's, this has become a major diagnostic procedure and has contributed to a significant reduction in open biopsies and, therefore, to medical cost-effectiveness immunobiochemical techniques provided us with a supplement to cancer diagnosis in the 1980's. The immunoperoxidase method, using monoclonal antibodies, is applied primarily as an ancillary measure to elucidate the nature of cancers The availability of specific monoclonal antibodies has greatly facilitated the identification of cell products or surface markers. For example, antibodies directed against intermediate filaments have proved to be of value in determining the histogenesis oi poorly differentiated neoplasms. Tumor markers may serve as biochemical indicators of the presence of a neoplasm. They can be detected In plasma and other body fluids. Their concentration can be applied as a diagnostic test, for monitoring the clinical course of known cancer, and as a screening measure to detect certain cancers in a population at risk. Flow cytometry is a useful tool for distinguishing several cell characteristics, such as the immunophenotype of leukemia-lymphoma cells, the DNA content of neoplastic cells, and cell proliferation rate. Molecular biologic techniques provided a giant step for the management of cancer patients encompassing diagnosis, prognostic evaluation, and therapy. Nucleic acid hybridization techniques are utilized as Southern, Northern, and dot blots and in situ hybridization. Molecular biology and its techniques may bring a blight new horizon for understanding cancer biology and in designing therapy on the basis of gene manipulation.

• Journal of Industrial Convergence
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• v.20 no.8
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• pp.33-40
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• 2022

In this study, we tried to suggest a plan to improve the efficiency of operation after analyzing the actual conditions by selecting case areas operated by the cadastral resurvey responsible agency system. The research results are as follows. In the evaluation of the selection of a cadastral resurvey agency, a method to raise the qualitative evaluation score was suggested. The expansion of support for the cadastral resurvey agency made it possible to automatically connect and install when the LandyGo program is updated, and suggested that prior training should be stipulated in the related regulations. In the performance of cadastral resurvey surveying and division of duties, the installation of temporary boundary monuments and determine boundary monuments should be integrated. And this suggested the direction of conserving the project cost of the cadastral resurvey agency through joint implementation. Also, in the short-term and long-term perspectives, a plan for realization of project cost distribution in connection with the expansion of the entrustment of the cadastral resurvey responsible agency was presented. If the responsible agency system is operated by reflecting the results of this research, it is expected to improve the satisfaction of the project participants and shorten the project period.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.17 no.5
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• pp.65-76
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• 2018

This study aims to evaluate the legibility distances of variable speed limit sign(VSL) for different sizes, luminances, and fog conditions through a field experiment. For this, extensive fog simulated environment has been constructed, and legibility distances are tested and recorded among test subjects for different luminances and sizes of VSL in control. Results showed that legibility distance increased as the size of VSL increased in the given illumination conditions, but it was not an exact linear trend. The size was also an important factor for determining legibility distance as the fog density increased, especially heavy fog conditions. In addition, the legibility distance also increased as the given illumination levels of VSL improved.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.2
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• pp.297-306
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• 2022

AtoN is an acronym for aids to navigation that indicate the position or direction of navigable areas and obstructions. AtoN should be arranged in consideration of unfamiliar navigator's convenience when it is indicated as the limits of navigable areas. Several narrow channels exist on the SW coast of Korea owing to the geographical effect, and the lateral or cardinal marks by the IALA maritime buoyage system are arranged along the narrow channels. This is an actual case study that analyzed the AtoN's role for safety navigation after changes in the maritime traffic environment owing to aquarfarm's development on narrow channels in the Korean SW coast. The analysis results of 5 narrow channels indicated that certain marks did not function properly as lateral or cardinal marks owing to the aquarfarm's location on navigable areas. Therefore, the following were suggested to improve AtoN on narrow channels: changing the position of marks, installing aquafarm's marks, and expressing the aquafarm's position on the nautical chart.

• Journal of the Korea Institute of Building Construction
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• v.13 no.6
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• pp.557-564
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• 2013

Unsafe and dangerous factors or environments on building construction sites often cause safety accidents. Sometimes, accidents happen despite the existence of warning and caution signs. Such warning signs are likely to be hidden by stacked materials or temporary facilities on site. If workers cannot see the signs when moving or working, they could be injured, sometimes fatally. Many studies have focused on each worker's position, and various systems have been developed using GPS signals and sensors. This paper suggests a method for identifying the problem of worker inability to see the unsafe factors, to manage the problem in the construction planning phase by considering things from the worker's perspective. The method uses CAD software to investigate the relation between the height of stacked materials and the visible ratio of the unsafe factor. The results of a sample project show that the changes in the height and location of stacked materials make the site safer.

• Parasites, Hosts and Diseases
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• v.33 no.4
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• pp.341-348
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• 1995

Genetic status of Acnnthamoebc sap. were tested on the basis of random amplified polymorphic DNA (RAPD) marker analysis. Four previously established Accnthcmoebn species, 4 Korean isolates of Acnnthamoeba sp., and one American isolate of Acanthcmoebc sp. were analyzed by RAPD-PCR using an arbitrary decamer primers. Amplification products were fractionated by agarose gel electrophoresis and slainrd by ethidium bromide . Eighteen primers produced DNA amplification profiles revealing clear differences among 4 species. Nine of them also produced DNA amplification profiles which included some isolate-specific amplification products. On the basis of amplified fragments by 18 primers, the pairwise similarity indices between A. culbensoni and other species (i.e. A. hntchetti, A. trinngularis, A. polyphaga) were 0.300, 0.308, and 0.313, respectively. Similarity index between A. hctchetti and A. triansulcris was 0.833. The mean similarity index among the 3 Korean isolates (YM-2, -3, -4) was 0.959 and 0.832 among them and 2 other species (A. hatchetti and A. triongulnris). The mean similarity index among YM-5 and other Korean isolates (YM-2, -3, -4) was 0.237. However, the similarity index between YM-5 and A. culbeksoni was 0.857, which suggests that YM-5 is genetically more similar to A. culbertsoni than other Korean isolates. Phonogram reconstructed by UPGMA method revealed that there are two groups: one group consists of A. hctchetti, A. tlonsulcns, and 3 Korean isolates (YM-2, -3, -4) , and the other group consists of A. cuLbensoni. A. polwphosc, HOV, and YM-5.

• Journal of Genetic Medicine
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• v.5 no.2
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• pp.125-130
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• 2008

Propose: To analyze the indications and cytogenetic results of midtrimester amniocentesis. Material and Methods: This study reviewed 2,523 cases of midtrimester prenatal genetic amniocentesis performed at MizMedi Hospital between January 2000 and December 2007. Results: The most frequent indication for midtrimester amniocentesis was advanced maternal age (45.9%), followed by positive serum markers (29.9%). Chromosomal aberrations were diagnosed in 110 cases (4.4%), for which numerical aberration accounted for 38 cases (34.5%), structural aberration accounted for 65 cases (59.1%), and mosaicism accounted for 7 cases (6.4%). Among the autosomal aberrations, there were 20 cases of trisomy 21 and 8 cases of trisomy 18. With respect to structural aberrations, there were 14 cases of reciprocal translocation and 8 cases of robertsonian translocation. The frequencies of chromosomal aberrations according to the indication were highest in individuals with a family history of chromosome abnormality 14.0% (8/57) followed by previous congenital anomaly 5.9% (2/34). Conclusion: Midtrimester amniocentesis is an effective tool for prenatal diagnosis. Indications such as advanced maternal age, maternal serum markers, and ultrasound are important for predicting abnormal fetal karyotypes.

• Journal of Life Science
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• v.27 no.2
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• pp.233-240
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• 2017

Previously, we have shown that Schisandra chinensis (Turcz.) Baill. (S. chinensis) has a protective effect against endoplasmic reticulum (ER) stress-induced hepatic steatosis. Gomisin A is a bioactive phytoestrogen derived from S. chinensis. In the present study, the in vitro and in vivo effects of gomisin A on ER stress and hepatic steatosis were investigated. We quantified the expression of markers of ER stress, including glucose regulated protein 78 (GRP78), C/EBP homolog protein (CHOP), and X-box-binding protein-1 (XBP-1), in HepG2 cells treated with tunicamycin or palmitate. Tunicamycin treatment in HepG2 cells induced the expression of markers of ER stress, including GRP78, CHOP, and XBP-1c. However, treatment with gomisin A reduced the expression of markers of ER stress. These inhibitory effects were also observed in palmitate-incubated HepG2 cells. The in vivo inhibitory effects of gomisin A were assessed in mice injected with tunicamycin or fed with a high fat diet (HFD). Gomisin A reduced the expression of markers of ER stress and decreased triglyceride levels in the livers of mice after tunicamycin injection or HFD feeding. Furthermore, gomisin A decreased the expression of inflammatory genes in palmitate-incubated HepG2 cells and the liver of HFD-fed obese mice. These results suggest that gomisin A inhibits ER stress and ameliorates hepatic steatosis induced by ER stress.

• Korean Journal of Clinical Laboratory Science
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• v.54 no.4
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• pp.256-264
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• 2022

Ischemic stroke is caused by an occlusion by a thrombus or embolus in a cerebral artery, preventing oxygenated blood from reaching the brain and causing the necrosis of nerve cells. This paper summarizes the serum candidate markers associated with cardiovascular disease and atrial fibrillation (AF) disease that enable an early diagnosis of ischemic stroke studied thus far and compares the odds ratio (OR) of each marker. This study examined the effect size of these serum candidate markers using meta-analysis techniques. The academic database search screening for articles containing the keywords "cardiovascular disease," "atrial fibrillation," "ischemic stroke," and "serum marker" was limited to results for patients with ischemic stroke. The most derived markers in this study were N-terminal pro-B-type natriuretic peptide (NT-pro-BNP), D-dimer, C-reactive protein (CRP), and glial fibrillary acidic protein (GFAP), the rest being investigated individually. In conclusion, NT-pro-BNP appears to be very useful for the early diagnosis of ischemic stroke. Primarily, it is a marker of AF, and more AF markers will be uncovered and studied in the future.