• Radiation Oncology Journal
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• v.23 no.2
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• pp.61-70
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• 2005

Purpose: Uterine cervix cancer is one of the most prevalent women cancer in Korea. We analysed published papers in Korea with comparing Patterns of Care Study (PCS) articles of United States and Japan for the purpose of developing and processing Korean PCS. Materials and Methods: We searched PCS related foreign-produced papers in the PCS homepage (212 articles and abstracts) and from the Pub Med to find Structure and Process of the PCS. To compare their study with Korean papers, we used the internet site 'Korean Pub Med' to search 99 articles regarding uterine cervix cancer and radiation therapy. We analysed Korean paper by comparing them with selected PCS papers regarding Structure, Process and Outcome and compared their items between the period of before 1980's and 1990's. Results: Evaluable papers were 28 from United States, 10 from the Japan and 73 from the Korea which treated cervix PCS items. PCS papers for United States and Japan commonly stratified into $3\~4$ categories on the bases of the scales characteristics of the facilities, numbers of the patients, doctors, Researchers restricted eligible patients strictly. For the process of the study, they analysed factors regarding pretreatment staging in chronological order, treatment related factors, factors in addition to FIGO staging and treatment machine. Papers in United States dealt with racial characteristics, socioeconomic characteristics of the patients, tumor size (6), and bilaterality of parametrial or pelvic side wail invasion (5), whereas papers from Japan treated of the tumor markers. The common trend in the process of staging work-up was decreased use of lymphangiogram, barium enema and increased use of CT and MRI over the times. The recent subject from the Korean papers dealt with concurrent chemoradiotherapy (9 papers), treatment duration (4), tumor markers (B) and unconventional fractionation. Conclusion: By comparing papers among 3 nations, we collected items for Korean uterine cervix cancer PCS. By consensus meeting and close communication, survey items for cervix cancer PCS were developed to measure structure, process and outcome of the radiation treatment of the cervix cancer. Subsequent future research will focus on the use of brachytherapy and its impact on outcome including complications. These finding and future PCS studies will direct the development of educational programs aimed at correcting identified deficits in care.

• Journal of the Korean Association of Geographic Information Studies
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• v.21 no.2
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• pp.1-23
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• 2018

This study aims to propose a way for evaluating thermal environment vulnerability associated with policy to improve thermal environment. For this purpose, a variety of indices concerning thermal vulnerability assessment and adaptation policies for climate change applied to 17 Korean cities were reviewed and examined. Finally, 15 indices associated with policies for improving thermal environment were selected. The selected indices for thermal vulnerability assessment were applied to Daegu Metropolitan City of South Korea as a case study. As results, 15 vulnerability maps based on the standardized indices were established, and a comprehensive map with four grades of thermal vulnerability were established for Daegu Metropolitan City. As results, the area with the highest rated area in the first-grade(most vulnerable to heat) was Dong-gu, followed by Dalseo-gu and Buk-gu, and the highest area ratio of the first-grade regions was Ansim-1-dong in Dong-gu. Based on the standardized indices, the causes of the thermal environment vulnerability of Ansim-1-dong were accounted for the number of basic livelihood security recipients, the number of cardiovascular disease deaths, heat index, and Earth's surface temperature. To improve the thermal environment vulnerability of Ansim-1-dong, active policy implementation is required in expansion and maintenance of heat wave shelters, establishment of database for the population with diseases susceptible to high temperature environments, expansion of shade areas and so on. This study shows the applicability of the vulnerability assessment method linked with the policies and is expected to contribute to the strategic and effective establishment of thermal environment policies in urban master district plans.

• The korean journal of orthodontics
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• v.36 no.1 s.114
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• pp.74-83
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• 2006

Analysis of lateral cephalometric radiograph (cephalogram) has been used routinely to evaluate skeletal and dental relationships, but analysis of the lateral facial photograph has not been used frequently for evaluation of skeletal relationships. As concerns about harm of X-ray irradiation increases, this study was planned to evaluate the possibility of substituting analysis of the lateral cephalogram with analysis of the lateral facial photograph by comparing these two analyses. According to the ANB values from cephalometric analysis, subjects were divided into three groups: Class I malocclusion group (n=32). Class II malocclusion group (n=32), and Class III malocclusion group (n=31). After measurements of angles indicating horizontal and vertical relationships of the maxilla and mandible on the lateral cephalograms and photographs, differences between Class I, II and III groups were evaluated. To evaluate the similarity between two similar values in the cephalograms and photographs, t-test using standardized variable Z and correlation analysis were performed in the Class I malocclusion group. The results showed that 1) SnN'Pg' on the photograph can be used to evaluate the antero-posterior relationship of the maxilla and mandible (ANB), 2) N'-Sn/Sn-Pg' on the photograph can be used to evaluate facial convexity (NA/APg), 3) Sn-Tra-Me' on the photograph can be used as a measurement similar to FMA. In conclusion, partly substituting lateral cephalogram analysis with lateral facial photograph analysis was possible in the evaluation of the maxilla and mandible.

• Radiation Oncology Journal
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• v.3 no.2
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• pp.95-101
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• 1985

From July 1979 through March 1985,112 patients with carcinoma of the uterine cervix were treated by whole pelvis irradiation and intracavitary radiation with Cs-137. The treatment consisted of 3600rad-5200rad to the whole pelvis by parallel opposing portals, 5 days per week, 180-200rad per day. Parametrial boost with 400-800rad was given in 60 patients. 2 intracavitary Cs-137 radiation using TAO applicator were done with 7-10 days interval. Total treatment times were 40-65 days with average 52 days. Total dose of radiation to point A varied from 6820 to 10500rad with average 8388rad and to point B from 4850 to 6899ra0 with average 5898rad. All patients had follow up from 6 months to 75 months and median follow up of 31 months. $9(8\%)$ had stage $14(12.5\%)$ had stage IIa, $50(44.6\%)$ had stage IIb, $33(29.5\%)$ had stage III, $6(5.4\%)$ had stage IV. 110 patients had squamous cell carcinoma and 2 patients had adenocarcinoma. 5 year actuarial survival rates were $61.8\%$ for the entire group, $84.6\%$ for stage Ib,$77.8\%$ for stage IIa, $56.7\%$ for stage IIb, $60\%$ for stage III, $33.3\%$ for stage IV. RT dose to medial parametrium (point A) below 8000rad resulted in $7/18(38.9\%)$ failure (=death) in contrast to 25/94 $(26.5\%)$ failure with dose over 8000rad. RT dose to lateral parametrium (point B) below 6000ra0 yielded 20/63 $(34.9\%)$ failure compared to $10/49(20.4\%)$ failure with dose over 6000rad. Poor survival group of age were between 40-49 years with failure of $14/41(34.1\%)$. There was no increased failure rate below age of 40 with failure of $2111(13.9\%)$. The results suggest that survival is as good as other published data, and that higher doses over 8000rad to point A and 6000rad to point B should be delivered.

• The Korean Journal of Nuclear Medicine Technology
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• v.13 no.3
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• pp.31-42
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• 2009

Purpose: As the number of domestic medical institutions installing PET/CT is increasing rapidly, the transfer of PET/CT images among medical institutions is also increasing. Thus, it is necessary to collect the comparative SUV data from several medical institutions' PET/CT systems through a phantom study which semi-quantitatively compares the SUV on one bed, the change scale of the SUV on the slices, and the time of measuring. The phantom study to find differences among the SUVs from various PET/CT offers the opportunity to obtain the reliability of the SUV in PET/CT images. Materials and Methods: Ten PET/CT systems from medical institutions in Korea were used. To obtain the accurate data, the study has been using the radiation detector of Korea Research Institute of Standards and Science to verify. The internal structures of NEMA $phantom^{TM}$ were removed and Six thousand milliliters of distilled water which has 1mCi of $^{18}F$-FDG put into the phantom. The water was properly integrated with $^{18}F$-FDG using magnetic stirrer. The images were acquired at 60, 70, 80, 90, 100, 110 and 120-minutes for 3 minute each. Two hundred square centimeters of region of interests were placed and analyzed. To confirm the usefulness, the correction-table came out from patients' data. Results: The coefficient of variability of the SUV from -11.0 to 9.90 % fell into the range of international standards(${\pm}10%$) along with the SUV on a bed, the change scale of the SUV on the slices, and the time of measuring, except one PET/CT system. Using the data of the differences among the SUVs, we came to withdraw the correction-table ranging from 0.803 to 1.246. The correction-table was confirmed its usefulness through Linear Regression Analysis which was applied to normal cases. Conclusions: Although studies have been made on the variation of the SUV, there is little attention on the standardization of the SUV. Based on this study of the quantitatively comparable data about the SUV accommodating the correction-table, it would help to have more corrective diagnosis.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.1
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• pp.22-29
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• 2007

Purpose: Metastatic thyroid cancers with I-131 uptake have been known to show no increase of FDG uptake whereas those without I-131 uptake tend to demonstrate increased uptake on PET. In this study, we evaluated the degree of FDG uptake in primary thyroid cancers of papillary histology before surgery. Material & Methods: Forty FDG PET studies were performed on the patients who had papillary cancer proven by fine needle aspiration. The degree of FDG uptake was visually categorized as positive or negative (positive if the tumor showed discernible FDG; negative if the tumor didn't) and the peak standard uptake value (peak SUV) of the papillary thyroid cancer (PTC) were compared with the size of PTC. Results: The mean size of 26 PTC with positive FDG uptake was $1.9{\pm}1.4\;cm(0.5{\sim}5\;cm)$. In 13 PTC with negative FDG uptake, the mean size of those was $0.5{\pm}0.2\;cm\;(0.2{\sim}0.9\;cm)$. All PTC larger than 1cm ($2.5{\pm}1.4\;cm,\;1{\sim}5\;cm$) have positive FDG uptake (peak $SUV=6.4{\pm}5.7,\;1.7{\sim}22.7$). Among the micropapillary thyroid cancer (microPTC; PTC smaller than 1cm), 8 microPTC show positive FDG uptake(peak $SUV=2.9{\pm}1.3,\;1.7{\sim}5.5$), while 13 microPTC show negative finding(peak $SUV=1.3{\pm}0.2,\;1.1{\sim}1.7$). The size of microPTC with positive FDG uptake is significantly larger than that of microPTC with negative FDG uptake ($0.7{\pm}0.1\;cm$ vs $0.4{\pm}0.2\;cm$, p=0.01). Conclusion: All PTCs larger than 1cm show positive FDG uptake in our study. In other words, thyroid lesions larger than 1cm with negative FDG uptake are unlikely to be PTC. So far, only poorly differentiated thyroid cancers are known to show increased FDG uptake. Our results seem to be contradictory to what is known in the literature. Further study is needed to understand better the significance of increased FDG uptake in PTC in relation to expression of NIS and GLUT.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.416-424
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• 2017

This study was conducted to examine the awareness of workers in public institutions of automated external defibrillators, their usage intention and related educational experience in an effort to increase the efficiency of education and the rate of automated external defibrillator usage in emergency situations. The subjects in this study were 243 selected. male and female adults who worked in public institutions in Gangwon Province. A survey was conducted from June 13 to August 21, 2016. The statistical analysis was based on the frequency analysis and the $X^2$-test. There were significant differences among the public institution workers awareness of how to use an automated external defibrillator according to gender (${\chi}^2=6.32$, p<0.05) and academic credentials (${\chi}^2=5.91$, p<0.05). Additionally, there were significant differences in usage intention according to academic background (${\chi}^2=5.70$, p<0.05). The most common reason for having no intention to use an automated external defibrillator for patients with cardiac arrest was that the respondents did not know how to use it (31.5%). There were also significant differences in educational experience with automated external defibrillators according to age (${\chi}^2=6.15$, p<0.05), academic credentials (${\chi}^2=11.56$, p<0.01) and career (${\chi}^2=11.92$, p<0.01). The most common form of education that the workers received pertaining to automated external defibrillators was a combination of theoretical and practical education, which represented 55.9%. The findings of the study seem to suggest that workers in public institutions used by many people must receive compulsory standard education regarding automated external defibrillators and try to boost the revival rate of patients with cardiac arrest in real emergency situations.

• Journal of Sasang Constitutional Medicine
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• v.11 no.1
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• pp.137-157
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• 1999

The purpose of this study is to help classifying Sasang Constitution through correlation with sound characteristic. This study was done it under the suppose that Sasang Constitution has correlation with sound spectrogram. The following result were obtained about correlation between sound spectrogram and Sasang Constitution by comparison and analysis 1. Soeumin answered his voice low tone, smooth and quiet in the survey. Soyangin answered his voice high, clear, fast and speaking random. Taeumin answered his voice low, thick and muddy. 2. Taeyangin was significantly slow compared with the others in the time of reading composition. Taeyangin was significantly slow compared with the others in Formant frequency 1. Taeyangin was significantly discriminated from Soeumin in Formant frequency 5. Taeyangin was significantly low compared with the others in Bandwidth 2. Soeumln was significantly low compared with Taeyangin in Pitch Maximum and Pitch Maximum-Pitch Minimum. Taeyangin was significantly high compared with the others in Energy mean. 3. In list of specification, the discrimination rate was higher than that by lists of 13 in the results of Multi-dimensional 4-class minimum-distance. The discrimination rate of three disposition except Soyangin was higher than that of four disposition in the results of One way ANOVA and Analysis of dis crimination in SPSS/PC+. In CART, the estimate rate of Sasang Constitution discrimination was higher than any other method. It is considered that there is a correlation between sound spectrogram and Sasang constitution according to the results. And method of Sasang constitution classification through sound spectrogram analysis can be one method as assistant for the objectification of Sasang constitution classification.

• Nuclear Medicine and Molecular Imaging
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• v.43 no.1
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• pp.19-25
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• 2009

Purpose: The aims of this study were to analyze correlation between the maximum standardized uptake value (SUVmax) of 2-[F-18]-fluoro-2-deoxy-d-glucose (FDG) on positron emission computed tomography (PET-CT) scan and the degree of contrast enhancement on computed tomography (CT) scan in lung cancers, and to recognize the difference in SUVmax and CT enhancement between groups of different histopathologic subtypes. Materials and Methods: Our study included 53 patients of pathologically confirmed primary lung cancer, who were performed PET-CT and post-contrast chest CT. We calculated initial and delayed SUVmax (SUV1, SUV2), difference between SUV1 and SUV2 (SUVd), retention index (RI), and the degrees of CT contrast enhancement of lung cancers. We analyzed these variables for subtypes of lung cancers. Results: The values (mean$\pm$ standard deviation) were $8.3{\pm}4.4$ for SUV1, $10.7{\pm}5.7$ for SUV2, $2.4{\pm}1.6$ for SUVd, $30{\pm}14$ for RI and $47.1{\pm}14.8$ HU (Hounsfield Unit) for degree of CT contrast enhancement. The difference of SUV1 and degree of CT enhancement between subtypes was not meaningful. SUV1 showed positive correlations with SUVd (r=0.74, p<0,01) and tumor size (r=0.58, p<0.01), but no significant correlation with degree of CT enhancement (r=0.06, p=0.69). In 10 cases, there was discrepancy in the same mass between the area of highest FDG-uptake and the area of highest contrast enhancement. Conclusion: We suggest that FDG uptake in lung cancer does not have a positive linear correlation with degree of CT enhancement. And there is no significant difference in FDG uptake and degree of CT enhancement between different subtypes of lung cancers.

• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.2
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• pp.35-43
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• 2012

Purpose : PET/CT performed CT-based attenuation correction generates the beam hardening artifact by metallic implant. The attenuation correction causes over or underestimate of the area adjacent to metallic hip prosthetic material and change of $^{18}F$-FDG uptake. Also, the image quality and the diagnosability on genitourinary disease are reduced. Therefore, this study will evaluate the usefulness of MAR (Metal Artifact Reduction) algorithm method to improve the image quality on PET/CT. Materials and Methods : PET/CT was performed by fixing hip prosthesis in SPECT/PET phantom. In PET images with and Without MAR algorithm, the Bright streak, Dark streak, Metal region and Background area that appeared on CT were confirmed, and the change of each SUV (standardized uptake value) was analyzed. Also, in 15 patients who underwent total hip arthroplasty, each MAR algorithm and Without MAR algorithm and non attenuation correction was evaluated. Results : In PET image Without MAR algorithm, SUV of Bright streak region was $0.98{\pm}0.48$ g/ml; Dark streak region was $0.88{\pm}0.02$ g/ml; Metal region was $0.24{\pm}0.16$ g/ml, Background area was $0.91{\pm}0.18$ g/ml. In SUV of PET image with MAR algorithm, Bright streak region was $0.88{\pm}0.49$ g/ml, Dark streak region was $0.63{\pm}0.21$ g/ml, Metal region was $0.06{\pm}0.07$ g/ml, Background was $0.90{\pm}0.02$ g/ml. SUV generally decreased when applying MAR algorithm. In PET image Without MAR algorithm, SUVs of Bright region were higher than those measured in the Background, and it was false positive uptake. But, in PET image with MAR algorithm, SUVs of Bright region were similar to the Background, and false positive uptake disappeared. Conclusion : MAR algorithm could reduce an increase of $^{18}F$-FDG uptake due to attenuation correction in the hip surrounding tissue. However, decrease of SUV in Dark streak region should be considered in the future. Therefore, this study propose that the diagnostic accuracy can be improved in genitourinary diseases adjacent to metallic hip prosthesis, if provided PET images with and Without MAR algorithm, and non attenuation correction images at the same time.