• Title/Summary/Keyword: 폐 전이

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Effect of Lindera obtusiloba extract on cancer metastasis (생강나무 추출물의 암전이 억제효과)

  • Yun, Hyuk;Lee, Yong-Jae;Seo, Hyun-Won;Park, Kyoung-Jae;Ko, Ha-Neul;Cha, Dong-Seok;Kwon, Jin;Jeon, Hoon;Kim, Kang-San
    • The Journal of Internal Korean Medicine
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    • v.33 no.4
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    • pp.405-417
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    • 2012
  • Objectives : In the present study, anti-metastatic properties of the methanol extract of L. obtusiloba (MLO) were evaluated. Methods : To determine the effect of MLO on cancer metastasis, we checked matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) activities and expressions in B16F10 melanoma cells. In addition, we performed cell migration assay as well as invasion assay using Matrigel. Finally, we used an in vivo lung metastasis model to confirm the anti-metastatic activity of MLO. Results : 1. MLO showed potent inhibitory effects on MMP-2 and MMP-9 activities and expressions via down-regulation of activation of NF-${\kappa}B$ in B16F10 melanoma cells. 2. Melanoma cell migration and invasion were down-regulated by MLO treatment. 3. Not only in vitro model, but MLO also significantly suppressed lung metastasis in vivo. Conclusions : The present results indicate that MLO has strong inhibitory effect on cancer metastasis. Therefore, L. obtusiloba could be a valuable anti-metastatic agent.

Regeneration of Spent Nickel Catalyst for Hydrogenation (수소화 반응용 니켈 폐촉매의 재생)

  • 전종기;박영권;김주식
    • Resources Recycling
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    • v.13 no.3
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    • pp.27-36
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    • 2004
  • Nickel oxide was recovered through roasting of a spent catalyst for hydrogenation reaction. Nickel on Kieselguhr catalysts were prepared by a precipitation method after a treatment of the recovered-nickel oxide with an acid. Effects of roasting temperature of the spent catalyst on recovery of nickel oxide was investigated. Most of nickel oxide could be recovered through roasting of the spent catalyst at $1000^{\circ}C$. In regeneration of catalysts by the precipitation method after the treatment of nickel oxide with an acid, the effect of promoter, precipitation condition and reduction condition on catalytic performance in vegetable oil hydrogenation were investigated. The addition of CaO or $Ce_2$$O_3$ resulted in an increase of catalytic activity.

Inflammatory Pseudotumor of the Entire Left Lung -1 operative case report (좌측 전폐에 발생한 염증성 가성 종양 -수술치험 1례 보고-)

  • 전양빈;이재훈
    • Journal of Chest Surgery
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    • v.30 no.4
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    • pp.437-440
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    • 1997
  • A case of inflammatory pseudotumor of the entire lung In a 61-ycar-old man is prcscntcd. The respiratory symptoms developed 2 months ago and progressed rapidly and the diagnosis of chronic pneumonia with ateletectasis of the entire lung, destroyed lung by tuberculosis and sepsis hAd to be ruled out The operative finding was different from our expectation. This case suggests that the Inflammatory pseudotumor can manifest as a whole lung-involving ass. Inflammatory pseudotumor is a nonneoplastic reactive pulmonary mass lesion that resembles tumor but shows little or no growth. Thc inflammatory pseudotufor usually present as a solitary round lung mass but in this casts progressed rapidly and destroyed the whole lung, which is rare. The patient was discharged with no problem and with outpatient followup.

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A Study on the Magnetic Separation of Magnetite from Spent Iron-oxide Catalyst (폐 산화철촉매로부터 마그네타이트의 자력선별에 관한 연구)

  • 현종영;이효숙;이우철;채영배
    • Resources Recycling
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    • v.11 no.3
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    • pp.31-36
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    • 2002
  • Magnetic separation was carried out in order to improve the magnetite grade of the spent iron oxide catalyst, that was composed with magnetite, ceria and soluble alkaline salt. The recovery of magnetite from the spent iron oxide catalyst was over 99%, and the magnetite contents was upgraded to about 80% from 70% via wet type magnetic separation at 500 Gauss. This improvement was due to the removal of alkaline salt by water instead of the magnetic separation.

A Clinical Analysis on 8 cases of Pulmonary Sclerosing Hemangioma (폐 경화성혈관종 8예에 대한 임상적 고찰)

  • Chang, Jung-Hyun;Kim, Se-Kyu;Kim, Hyung-Jung;Kwon, Seon-Ok;Chung, Kyung-Young;Shin, Dong-Hwan;Lee, Doo-Yun;Ahn, Chul-Min;Kim, Sung-Kyu;Lee, Won-Young
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.4
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    • pp.384-389
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    • 1993
  • Background: Pulmonary sclerosing hemangioma is rare, but still the second most common benign lung tumor, occurring most1y in middle-aged women. Methods: From January 1985 through April 1993, we experienced eight cases of solitary pulmonary sclerosing hemangioma. Results: Subjects studied were 7 female and 1 male patients. They ranged from 14 to 63 years of age(mean age, 43.8 years) at the time of operation. The patients were frequently asymptomatic and the tumor was often shown to be a large lobulated mass on radiographic examination. The tumor can usually be diagnosed on operation because of its subtle clinical and radiographic presentation. All eight cases were diagnosed intraoperatively. The mean interval between initial radiographic detection and operation was 7.9 months. Out of 8 cases, preoperative impression of benign tumor was made in 4 cases, whereas malignant tumor was suspected in the remaining 4 cases. Enucleation, wedge resection or lobectomy was performed which appropriate in each patient. Conclusion: Surgical removal of the tumor preserving as much lung parenchyma as possible is indicated for proper diagnosis and treatment of this condition.

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Surgical Treatment of Pulmonary Blastoma -A Case Report- (폐 모세포종의 외과적 치료 -1례 보고-)

  • 양수호;김병일
    • Journal of Chest Surgery
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    • v.30 no.10
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    • pp.1044-1047
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    • 1997
  • Pulmonary blastoma are a family of tumors in which the glands or mesenchyme composing the neoplasm are primitive or emb yonal in appearance. We report a pulmonary blastoma occurring in a 31 years old man. An abnormal shadow was detected in the right lower lung field in a routine chest X-ray film. The preoperative imaging films showed about a 5cm sized well circumscribed solid tumor of the right lung. A preoperative clinical diagnosis of primary lung cancer was considerd. The operative field showed that the hard, round mass, 6$\times$5$\times$4cm in diameter was localized in middle lobe of the right lung, and partially adhered to the upper lobe, pericardium and diaphragm. Right middle lobe lobectomy, right upper lobe wedge resection, partial pericardiectomy and diaphragm resection with plication was performed with radical Iymph node dissection. Histopathologic diagnosis was pulmonary blastoma (Biphasic blastoma). It is considered that the prognosis of biphasic blastoma is worse than WDFA(well differentiated fetal adenocarcinoma). There are no other available treatments except for surgical resection. It is suggeste that it is necessary to collect as many cases as possible, to make definite classifications and to examine the clinical course and prognosis of pulmonary blastoma.

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A Study on the Effectiveness of the Lungs Hand Acupuncture Based on Bio Signal Analysis (생체신호분석 기술을 적용한 폐 수지침 요법에 대한 효과성 연구)

  • Kim, Bong-Hyun;Cho, Dong-Uk
    • The KIPS Transactions:PartB
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    • v.19B no.2
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    • pp.77-82
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    • 2012
  • We carried out study to prove effectiveness as stimulating corresponding points to lung in hand to experiment applied analysis parameters for image and audio signals in this paper. To this end we collected facial image and voice before and after stimulating corresponding points to lung in hand to a male 20s 25 people. In addition, we analyzed change color, voice energy and speaking rate of right cheek area corresponding points to lung to suggest the theory of the Oriental medicine diagnosis based on data collected. As a result, after performing hand acupuncture, L value of right cheek area decreased average 2.33 and a value b value increased 0.76, 0.97 on average. In addition, size of voice energy increased average 0.42, speaking rate decreased average 0.07. In other words, effect of lung function was improved using hand acupuncture corresponding points to lung.

A basic study on the recovery of Ni, Cu, Fe, Zn ions from wastewater with the spent catalyst (폐산화철촉매에 의한 폐수중 Ni, Cu, Fe, Zn이온 회수에 관한 기초연구)

  • Lee Hyo Sook;Oh Yeung Soon;Lee Woo Chul
    • Resources Recycling
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    • v.13 no.2
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    • pp.3-8
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    • 2004
  • A basic study on the recovery of heavy metals such as Zn, Ni, Cu and Fe ions from wastewater was carried out with the spent iron oxide catalyst, which was used in the Styrene Monomer(SM) production company. The heavy metals could be recovered more than 98% with the spent iron oxide catalyst. The alkaline components of the spent catalyst could be precipitated the metal ions of the wastewater as metal hydroxides at the higher pH 10.6 in Ni, pH 8.0 in Cu, pH 6.5 in Fe, pH 8.5 in Zn. But the metal ions are adsorbed physically on the surface of the spent catalyst in the range of the pH of the metal hydroxides and pH 3.0, which is the isoelectric point of the iron oxide catalyst.

Study on Production of Glycerol Derivative from Bioglycerol (바이오디젤 부산물인 폐글리세롤을 이용한 유도체 생산에 관한 연구)

  • Ryu, Young-Bok;Lee, Sun-Do;Lee, Man-Sig
    • Proceedings of the KAIS Fall Conference
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    • 2010.11a
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    • pp.298-300
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    • 2010
  • 화석 연료인 석유, 천연가스, 석탄의 점진적 고갈이 예상됨에 따라 전 세계는 석유와 유사한 성질을 갖는 바이오 오일을 에너지원 및 화학원료로 사용하려는 노력이 증가하고 있다. 바이오 오일 활용분야 중 가장 큰 부분을 차지하고 있는 것은 바이오 디젤로 식물성 오일과 알콜의 전이에스테르화 반응에 의하여 생산되며, 바이오 디젤 1톤당 100kg의 글리세롤이 부산물로 생성된다. 본 연구에서는 바이오 디젤 부산물인 폐글리세롤을 이용하여 다양한 유도체의 생산 및 그 유도체의 가능성에 대하여 살펴보았다.

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Biodiesel Production from Lard & Beef Tallow Using Various Catalyst (돈지 및 우지 추출오일의 촉매 종류에 따른 바이오디젤 생산 특성)

  • Kim, Deogkeun;Lee, Youngjae;Park, Jiyeon;Park, Soonchul;Lee, Jinsuk
    • 한국신재생에너지학회:학술대회논문집
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    • 2011.05a
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    • pp.177.1-177.1
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    • 2011
  • 국내 바이오디젤의 원료로 사용되는 식물성 오일은 거의 전량이 수입된 것으로 원료를 자급화 하기 위한 방안으로 국내 동물성 폐자원을 이용한 바이오디젤 연구가 활발히 진행되고 있다. 본 연구에서는 전자레인지를 이용해 동물성 폐자원인 폐돈지 및 폐우지로부터 오일을 추출 후 물성을 분석하고 전이에스테르화 반응을 진행하였으며 바이오디젤 제조 특성을 조사하고자 하였다. 전이에스테르화 반응에 사용되는 염기 촉매를 몇가지 선정하여 각각의 촉매에 따른 바이오디젤의 반응특성을 메탄올 양을 변화시키며 조사 실험하였다. 기존에 사용된 바이오디젤 제조 촉매는 KOH를 주로 사용하였으며 본 연구에서는 KOH, NaOH, $NaOCH_3$를 촉매로 사용하여 오일질량 대비 0.8~1.2%의 촉매를 사용하였으며 메탄올의 양은 오일 몰수 대비 6:1~12:1의 비율로 사용하여 반응시간에 따른 반응특성과 제조 바이오디젤의 물성을 분석해 각 촉매에 따른 바이오디젤 생산 특성을 비교분석하였다.

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