• Journal of Chest Surgery
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• v.30 no.8
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• pp.823-826
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• 1997

Myocardial abscess usually occurs as a complication of infective endocarditis or overwhelming septicemia. Coronary artery occlusion caused by myocardial abscess has been rarely reported. A 61-year-old man presented with fever and chill that developed 6 weeks prior to admission. He had a history of cardiopulmonary resuscitation for ventricular fibrillation and cardiac arrest 4 weeks prior to admission. Echocardiography showed a 3xfcm sized mass in the area of the right atrioventricular groove and coronary angiography showed complete occlusion of the proximal right coronary artery. Under the diagnosis of myocardial infarction complicating myocardial abscess, debridement of abscess and coronary artery bypass grafting with right internal mammary artery to distal right coronary artery was performed. Culture from the abscess cavity demonstrated Salmonella arizona.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1983.05a
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• pp.17.5-18
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• 1983

Angiofibroma in otorhinolaryngologic field is rare, highly vascular and non-metastatizing benign tumor. It was noted as histologically benign but clinically malignant tumor because of the anatomical site, severe bleeding in surgery and recurrence in incomplete removal. It occurs almostly in nasopharynx of adolescent males. Recently, the authors have experienced a very rare case of angiofibroma which occupied the nasal septum in a 37-years-old-male with complaints of nasal obstruction and frequent nasal bleeding. The tumor mass was removed surgically through intranasal approach under local anesthesia. We report our case with review of current literatures.

• Journal of Digestive Cancer Research
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• v.1 no.1
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• pp.1-5
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• 2013

Incidence of colorectal cancer has been increasing in Korea probably due to the westernized life style. Although the technical development of colonoscopy and introduction of screening examination has led to the detection of early colorectal cancer, considerable patients still have clinical symptoms of colorectal obstruction. Most of these patients are old and they have advances stage of cancer or severe co-morbidities. In addition, the emergency operation under poor preparation state of colon can lead to serious mortality or complications. Since the introduction of colorectal stent, there have been a large number of studies for recent 10 years. It seems that the role of colorectal stent in the palliative indication or bridge to surgery has been recognized. A well designed, randomized prospective study with long term data is necessary to support the role of colorectal stent in the malignant colorectal obstruction.

• Journal of Yeungnam Medical Science
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• v.9 no.1
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• pp.167-174
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• 1992

Microvascular tissue transfers have facilitated primary closure of various complex defects after radical ablation of head and neck cancers. From Oct 1991 to Feb 1992, we used forearm free flap in two patients and delto-pectoral flap in one patient who had preoperative irradiation for pharyngoesophageal reconstruction. The stricture and fistular formation were most troublesome complication in forearm free flap, so we designed as lazy S shape in distal flap margin to prevent circular contraction and longitudinal margin was deepithelized(5mm) and sutured double layer to withstand fistular formation and this can be considered useful in place of a free jejunal transfer.

• Journal of Chest Surgery
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• v.37 no.7
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• pp.597-600
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• 2004

We report a rare case of pulmonary artery sarcoma mimicking pulmonary artery thromboembolism in a 57-year-old man who suffered with 2-month dyspnea and exacerbated for 1 week. He was transferred from private clinic and he was diagnosed as acute pulmonary artery thromboembolism on the basis of chest CT. Chest CT, pulmonary artery angiogram, and perfusion scan were examined. We performed surgical excision with aid of CPB. The final pathologic report was that the mass was a pulmonary artery sarcoma. We experienced one case of pulmonary artery sarcoma and reported it with reference.

• Journal of Veterinary Clinics
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• v.32 no.5
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• pp.440-444
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• 2015

The purpose of this case report was to present the treatment of continuous renal replacement therapy (CRRT) in dogs with end-stage CKD with uncontrolled uremia. Hemodialysis were carried out 6 patients who failed to improve clinical status with conventional management for CKD. Four dogs with urea reduction ratio (URR) range of 57-72% and 1 dog with URR of 37.3% showed good outcome with decreasing tendency of pre-dialysis Therefore, we suggest that CRRT could be recommended for use in CKD dogs with uncontrolled azotemia or uremia and should be monitor carefully throughout the CRRT.

• Journal of Chest Surgery
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• v.42 no.4
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• pp.532-536
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• 2009

Bypass surgery is performed for insuring continuity of a blood supply that is restricted due to obstruction of the native blood supply. Two types of surgery are commonly carried out: one is anatomic bypass and the other is extraanatomic bypass. Especially, extraanatomic bypass surgery is performed in patients who are a high risk for performing anatomical bypass surgery. The risk factors for anatomical bypass surgery are old age, infection, previous surgery and trauma. A 96-year-old patient underwent extraanatomic bypass surgery from the right femoral artery to the left femoral artery due to total occlusion of the left iliac artery, and 7 years after that operation, a pseudoaneurysm abruptly and spontaneously appeared from the bypass suture site without any predisposing factor. The lesion was revealed to be an organizing thrombus.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.1
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• pp.1-14
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• 2005

This study was performed to evaluate antithrombotic activities of Saegeumsan (瑞金散, SGS) which has effects of activating blood, removing thrombus. This study is designed to measure the effect which was given to blood flow rate through the regular volume of glass tube after the blood was diluted five times with ACD solution. Antithrombotic effect was calculated as a percentage of the experimental animal figure protected from the paralysis of hind legs or death of the mouse that is caused from the administration of platelet aggregation regent. We standardized the time when the experimental animals were incapable of functioning the hind legs more than 20 minutes or maintained trembling. Being classified one group of eight mice, each of them was divided into Normal, Control, and SGS. The normal group supplied a saline solution and the control group brought the dextran extravasated blood after an hour of administering the saline solution. Also, SGS was dissolved in $2m{\ell}$ saline solution and then we dosed it to the experimental mice with Oral Zonde one day before the experiment. After that, the mice were abstained from food. And then we gave a measured amount of it before an hour. Finally, it gave rise to dextran extravasated blood in the same way as the Control group. The results were obtained as follows, SGS significantly inhibited platelet aggregation induced by ADP and epinephrine when analyzed by the Sigmoid $E_{max}$ model in WinNonlin. $EC_{50}$ values of SGS were 4.61 mg/ml and 12.41 mg/ml for ADP and epinephrine respectively. SGS showed fibrinolytic activity insignificantly as compared with the control group. SGS increased blood flow rate significantly as compared with the control group in vitro. SGS inhibited pulmonary embolism induced by collagen and epinephrine(inhibitive rate is 37.5 %). SGS increased number of platelet and fibrinogen amount significantly, and shortened PT and APTT as compared with the control group in thrombus model induced by dextran. According to, SGS is effective antithrombotic activity from experimental result.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.467-467
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• 2016

암거는 일반적으로 용수나 배수용의 수로가 도로, 철도, 제방 등의 아래에 매설 된 수로를 지칭한다. 이러한 암거는 산업발전으로 사회기반시설의 신설 및 확충, 재정비 등으로 많이 활용되고 있다. 최근 들어 기후로 인한 재해가 급증하면서 이러한 시설물에 대한 안정성 및 관리에 대한 관심이 높아지고 있는 것이 현실이다. 특히 소하천은 집수면적 및 유로연장이 짧고 하상경사가 급하기 때문에 홍수에 취약하다. 즉, 빨라진 유속으로 인해 구조물 주변의 세굴에 의한 유실, 토사유출로 인한 하상퇴적, 부유물로 인한 차단으로 인해 통수에 지장을 받아 피해가 발생하게 된다. 이러한 암거시설물 피해는 2차 피해로 이어질 수 있으며 사회기반시설 파괴로 도시기능이 마비되고 인근 주변지역에 침수로 인한 재산 및 인명피해까지 발생시킬 수 있는 피해 잠재능력을 보유하고 있다. 그러나 피해에 대한 예방대책은 유지관리를 통해 지속적으로 관리하는 것이 대부분의 지침 등에 소개된 내용들이다. 본 연구에서는 암거를 대상으로 암거의 폐색으로 인해 암거주변에서 변화되는 흐름특성을 축소모형을 통해 검토하고자 하였다. 암거 축소모형실험은 1.5m 폭을 갖는 직선수로에서 수행하였으며, 암거모형은 도로암거표준도(2008)를 참조하여 $3m{\times}3m$ 수로암거를 대상으로 1/10 축소모형을 제작하였다. 암거유입부 퇴적으로 인한 암거의 차단률(차단면적/암거단면적)은 차단이 발생하지 않는 0% 조건에서부터 10%, 20%, 30%, 40%, 50% 조건에 대해 실험을 수행하였다. 실험결과 차단에 따른 암거 상류단의 수위는 차단이 없는 암거의 경우에 비해 차단율이 높아질수록 암거유입부 수위는 20.4% ~ 82.7% 상승하는 것으로 나타났다. 암거의 차단률이 40% 이상일 경우 높아진 수위로 인해 암거통로의 윗상면부까지 다다르고 있으며 50%일 경우 암거를 통과하는 흐름이 자유수면흐름이 아닌 오리피스 흐름이 발생하는 것으로 나타났다. 암거유입부 차단으로 인한 암거주변의 최대유속은 암거 직하류부에서 주로 발생하여 암거 유출부에서의 최대유속은 차단율이 증가할수록 선형적으로 증가하는 것으로 나타났으며 암거 유출부에서의 유속은 차단전의 조건(0%) 대비 4.2% ~ 35.5% 까지 상승하는 것으로 나타났다. 이와 같은 결과를 토대로 고려하였을 때 대부분 산지부에서 설치되는 암거의 경우 유속이 불가피하게 증가하게 됨으로 유속에 따른 유속조절방안(차단 및 우회시설) 및 세굴대책을 세워야 할 것으로 판단된다.

• Journal of Food Hygiene and Safety
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• v.36 no.5
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• pp.363-375
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• 2021

Trends in the developing era to discover and design peptide-based treatments throughout an epidemic infection scenario such as COVID-19 could progress into a more efficient and low-cost therapeutic environment. However, the weakening of proteolysis is one downside of natural peptide drugs. But, peptidomimetics may help resolve this issue. In this review, peptide and peptide-based drug discovery were summarized to target one key entry mechanism of severe coronavirus pulmonary emboli syndrome (SARS-CoV-2), which encompasses the association of the host angiotensin-converting enzyme-2 (ACE2) receptor and viral spike (S) protein. Furthermore, the benefits of proteins, peptides and other possible actions that have been studied for COVID-19 through new peptide-based treatments are discussed in the review. Lastly, an overview of the peptide-based drug therapy environment is comprised of an evolutionary viewpoint, structural properties, operational thresholds, and an explanation of the therapeutic area.