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A study on the theory of "Pyong-Yeol-Byong (評熱病論)" in 33th chapter of "SoMon (素問)" Yellow Emperor's Nei-Ching (黃帝內經) (황제내경(黃帝內經) 소문(素問) 평열병론(評熱病論)에 대(對)한 연구(硏究))

  • Moon, Hee-Seork;Hong, Won-Sik
    • Journal of Korean Medical classics
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    • v.3
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    • pp.399-443
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    • 1989
  • In this thesis, I intend to study the translational and clinical interpretation through the syndrom of "Pyong-Yeol-Byong", and reached the following conclusions. 1. Eum-Yang-Kyo (陰陽交)' 1) Meaning: "Eum" means "Essential and vital energy" "Yang" means "Evil factor affecting health" and "Kyo" means "cross-struggle." 2) Location of disease: Heat evil enter Hyeol-Bun (血分) 3) Pathogenesis: Heat evil invade Eum-Bun (陰分) and struggles with Health energy, therefore Eum-Chung (陰精) is exhausted and Heat-evil doesn't disapper, it damage Eum and exhaust fluid. Reach fever, rapid pulse raving and unable to take meal, not controled by sweating and sceach death. 4) Particularity of Syndrome: Heat enter Hyol-Bun, and Evil factor is enough and Health energy is insufficient, so that reveal the symptoms of high fever, delirium with coma, unable to take meals. 5) Therapy: It clears Gi-Bun heat evil (氣分熱邪) by Gypsum, Rhizoma Anemarrhenae, Flos Lonicerae, Fructus Forsythiae, Fructus Gardeniae, Radix Scutellanae Rhizoma Coptidis, and cools Blood by Cornu Rhinoceri Asiatici, Radix Rehmanniae, Cortex Moutan Radicis, Dae-Chung-Yob (大靑葉) Radix Arnebiae Seu Lithospermi. 2. Poong Gweol (風厥) 1) Meaning: Poong means wind-evil, Gweol means reversing up. 2) Location of disease: Disease complexes with TaeYang (太陽) in outer part, and with So-Eum (少陰) in inner part. 3) Pathogenesis: Tae-Yang-Gyeong (太陽經) accept wind-evil and So-Eum-Gyeong (少陽經) Kidney Energy reverse up so that fidgetiness not resolves by sweating. 4) Particularity of Syndrome: There are outer symptoms of fever, hydrosis with inner symptoms of fidgetinessis. 5) Therapy: Reduce Jok-Tae-Yang (足太陽) and Supply Jok-So-Eum (足少陰) by accupuncture, so cure Poong Gweol and make balance between Yeong (營) and Wi (衛). 3. Scrofula coused by wind-evil (勞風) 1) Meaning: It means accepting wind evil rest less. 2) Location of Disease: It locates lung 3) Pathogenesis: Because of accepting wind-evil restless, he take scrofula with damaging lung. 4) Particularity of disease: It is lung disease of aversion to wind and shiver, nape-stiffiness, dim eyesight, cough, disphea, vomitting sputum, if one camnot vomit sputum, he died by damage of lung. 5) Therapy: The period of therapy is different by age or strength of health energy, so I think must prevent Eum deficiency and clear fever no reduced in lung. 4. Shin-Poong (腎風) 1) Meaning: It means taking edema by accepting wind-evil, because the kidney controls water. 2) Location of Disease: It is that wind-evil envade kidney. 3) Pathogenesis : Water evil of kidney with wind-heat rises up to face, reach edema, puffines s of the lower eyelid, floating pulse, bombus, yellowish urine, hydrosis and hand-heating, drymouth and excessive thirsty, walkless by heaviness, menstrual disfunction, restless and unable to take meals, unable to lie flat, heavy cough if lie flat, and accepting wind-evil by deficiency of kidney function, so the function of dredging the water passage is not smooth, symptom of water and symptom of wind reveal together. 4) Therapy: Remove wind-heat, promote diuresis to eliminate tile wetness-evil, supplement the dificiency of kidney's Eum. Finally, we can know that later Fever Disease Medicime (溫病學) is affected to the theory of "Pyong Yeol Byong" in 33th Chapter of SoMoon (素問).

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Microbiological and Sensory Characteristics of Vacuum Packed Korean Chilled Pork Loins for Export (한국산 수출용 진공포장 냉장 돈육 등심의 미생물학적 및 관능적 품질특성)

  • Choi, Y.S.;Park, B.Y.;Lee, J.M.;Kim, I.S.;Lee, S.K.;Kim, B.C.
    • Journal of Animal Science and Technology
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    • v.44 no.3
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    • pp.351-360
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    • 2002
  • The Korean fresh pork loins in vacuum packaged were obtained from three different Korean export companies and investigated for microbiological and sensory properties. The fresh pork loins were stored at 2$^{\circ}C$ for 50 days and analyzed with an interval of 5$\sim$10 days. The results were as follows: The overall numbers of total plate counts and coliform bacteria were higher in swab method than in meat sampling method. The total plate counts in the loins from the company I were maintained low levels ($\prec$10$^5$ cfu/$cm^2$ or $\prec$10$^5$ cfu/g) for entire storage periods(50 days at 2$^{\circ}C$), whereas the loins from the company III had high levels when they were compared to the domestic standard for the allowance limit. The samples from the company III showed that total plate counts were over 106 after about 30 days when determined by meat sampling method and total plate counts were over 106 after 15 days when determined by swab method. The overall numbers of coliform bacteria were also significantly lowest in the samples from the company I, whereas they were highest in the company III. Therefore, all meat companies will have to make an effort to prevent bacterial contamination in each stage such as slaughtering, marketing and consumer in order to ensure the production of safe meat and the extension of shelf-life. For fresh products, scores of intramuscular fat were higher in samples form the companies II and III than those from the company I when visibly evaluated with the standard. There were no significant differences in scores of meat color, drip and fresh meat flavor. However, the samples from the company I had the lowest score of off-flavor and highest score of overall acceptability. For cooked products, there were no significant differences in meat flavor, off-flavor, juiciness and overall acceptability.

The study of binocular function of college students (대학생들의 시기능에 대한 연구)

  • Cho, Young-Rae;Park, Hyun-Ju;Seo, Ji-Keun;Seong, Jeong-Sub;Kim, Jae-Min
    • Journal of Korean Ophthalmic Optics Society
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    • v.10 no.2
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    • pp.103-110
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    • 2005
  • Binocular vision had a short history in Korea. As there were many near works in these days, the needs about comparative study have been increased. There was related to both refractive error and binocular anomalies, but it is difficult to applying for binocular vision expected findings in itself due to the fact that Korean differ from foreigner. Objects were 100 adults in 18-36 years old ages, The test was Von Gaefe method and used aparatus was phoropter(Shinnippon VT10)and visual chart(Shinnippon CT30). According to interview results was that symptom in near works were headaches 28.0%, blinking 27.3%, red eye 25.1%, eyepain 15.6%, watering 15.3%, itch 12.2%, photophobia 8.5% and eye strain 7.4%. A people who have above ${\pm}0.50$ D refractive error in total objectives (100-male 45/female 55) were classified into ametropia. There was a results such as emmetropia (12.0%), ametropia(88.0%), exophoria(32.0%), esophoria(12.0%). Far negative relative convergence were that in case of high 43.0%, in case of low 7.0%. Far positive relative convergence were that in case of high 15.0%, in case of low 38.0%. Near phoria was exophoria(32.0%), esophoria(12.0%). Near negative relative convergence were that in case of high 23.0%, in case of low 38.0%. Far positive relative convergence were that in case of high 29.0%, in case of low 23.0%. Near negative relative accommodation were that in case of high 10.0%, in case of low 14,0%, Far positive relative convergence were that in case of high 69.0%, in case of low 12.0%. Results were different from expected findings, and especially positive relative accommodation was very high, However, We suggest that the expected findings in Korea for several subjects must study in binocular function.

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Study on Relaxing Effect of Oxybutynin on the Contractile Response of Arterial Smooth Muscle (동맥근 수축에 대학 Oxybutynin의 이완효과에 관한 연구)

  • Ko, Jae-Ki;Baik, Yung-Hong
    • The Korean Journal of Pharmacology
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    • v.24 no.1
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    • pp.93-101
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    • 1988
  • Pharmacological actions of an antispasmodic agent, oxybutynin were investigated in the isolated procine coronary arteries. The coronary rings were contracted by acetylcholine (ACh) and KCl in a dose-dependent fashion. The ACh-induced contractions were signifcantly potentiated by removal of endothelium and $EC_{50}=0.52\;{\mu}M$ of intact endothelial rings was about 2 times greater than $EC_{50}=0.28\;{\mu}M$ of rings without the endothelium. These results suggest that the endothelium plays an inhibitory role in ACh-induced contraction. Oxybutynin and atropine inhibited dose-dependently $1.0\;{\mu}M$ ACh-induced contraction and atropine inhibited dose-dependently $1.0\;{\mu}M$ ACh-induced contraction and the $IC_{50s}$ were 11.0 nM and 0.47 nM, respectively. Atropine did not affect 35 mM KCl-induced contraction but oxybutynin inhibited the contraction to the basal tension in a dose-dependent manner. The $IC_{50}$ of oxybutynin on the KCl-induced contraction was $49.7\;{\mu}M$. The dose-response curve to ACh was parallelly shifted to the right by pretreating coronary rings with $IC_{50}$ of atropine (0.47 nM) or oxybutynin (11.0 nM) but the curve to KC1 was rightward shifted in a noncompetitive manner under pretreatment with $IC_{50}$ of oxybutynin $(49.7\;{\mu}M$). Oxybutynin inhibited $0.1\;{\mu}M$ Bay K 8644-induced contraction to the basal tension in a dose dependent manner, but $35\;{\mu}M$ histamine-induced contraction was inhibited to only 50e/e of the original level even in maximal concentration $(5{\times}10^{-4}M)$ of oxybutynin. These results suggest that oxybutynin causes antispasmodic action through sensitive blocking action on muscarinic receptors and inhibitory action on calcium influx in the procine coronary artery.

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Evaluate the implementation of Volumetric Modulated Arc Therapy QA in the radiation therapy treatment according to Various factors by using the Portal Dosimetry (용적변조회전 방사선치료에서 Portal Dosimetry를 이용한 선량평가의 재현성 분석)

  • Kim, Se Hyeon;Bae, Sun Myung;Seo, Dong Rin;Kang, Tae Young;Baek, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.27 no.2
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    • pp.167-174
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    • 2015
  • Purpose : The pre-treatment QA using Portal dosimetry for Volumetric Arc Therapy To analyze whether maintaining the reproducibility depending on various factors. Materials and Methods : Test was used for TrueBeam STx$^{TM}$ (Ver.1.5, Varian, USA). Varian Eclipse Treatment planning system(TPS) was used for planning with total of seven patients include head and neck cancer, lung cancer, prostate cancer, and cervical cancer was established for a Portal dosimetry QA plan. In order to measure these plans, Portal Dosimetry application (Ver.10) (Varian) and Portal Vision aS1000 Imager was used. Each Points of QA was determined by dividing, before and after morning treatment, and the after afternoon treatment ended (after 4 hours). Calibration of EPID(Dark field correction, Flood field correction, Dose normalization) was implemented before Every QA measure points. MLC initialize was implemented after each QA points and QA was retried. Also before QA measurements, Beam Ouput at the each of QA points was measured using the Water Phantom and Ionization chamber(IBA dosimetry, Germany). Results : The mean values of the Gamma pass rate(GPR, 3%, 3mm) for every patients between morning, afternoon and evening was 97.3%, 96.1%, 95.4% and the patient's showing maximum difference was 95.7%, 94.2% 93.7%. The mean value of GPR before and after EPID calibration were 95.94%, 96.01%. The mean value of Beam Output were 100.45%, 100.46%, 100.59% at each QA points. The mean value of GPR before and after MLC initialization were 95.83%, 96.40%. Conclusion : Maintain the reproducibility of the Portal Dosimetry as a VMAT QA tool required management of the various factors that can affect the dosimetry.

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A Study on the Motive and Evaluation of the Job for a Special Private Security Tasks (특수경비원의 직업선택동기와 직업평가에 관한 연구)

  • An, Hwang-Gwon
    • Korean Security Journal
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    • no.12
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    • pp.225-243
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    • 2006
  • This study is focused on the relation in the motive and the evaluation for the job in a special private security field. The supplement of the outstanding human resources is one of most important matter to improve the private security industry. For it the applicant's motive and evaluation of whose quality should be screened to recruit proper and oustanding human resources into the industry. For the study the follow elements would be considered. First, What is the real motive to apply the job and how prospect on the job the applicant will be taken. Second, what is different point of view to the job between male and female. Third, what relationship is in achieving the job performance between the temporary motive and the planed motive. Forth, what effects are on the job satisfaction and the planed motive for the job. With the above elements the survey was taken based on each sex for the study and the results are out as below. a) Male is in higher than female in taking with unplaned job motive and for job satisfaction is much higher in 1-20 age range. b) In general, the expectation on the job is much higher than the current job status, the male are in the expextation on the job and the female are in the the current job status. c) The job satisfaction is on positive effect to the planed taken job but the unplaned taken job is on negative. From the Research the most concerning element on the recruiting new employee is applicant's positive attitude on the job he/she will be taken.

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Development of High-performance Microwave Water Surface Current Meter for General Use to Extend the Applicable Velocity Range of Microwave Water Surface Current Meter on River Discharge Measurements (전자파표면유속계를 이용한 하천유량측정의 적용범위 확장을 위한 고성능 범용 전자파표면유속계의 개발)

  • Kim, Youngsung;Won, Nam-Il;Noh, Joonwoo;Park, Won-Cheol
    • Journal of Korea Water Resources Association
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    • v.48 no.8
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    • pp.613-623
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    • 2015
  • To overcome the difficulties of discharge measurements during flood season, MWSCM(micowave water surface current meter) which measures river surface velocities without contacting water has been applied in field work since its development. The existing version of MWSCM is for floods so that its applicability is low due to the short periods of floods. Therefore the renovative redesign of MWSCM to increase the applicability was conducted so that it can be applied to the discharge measurements during normal flows as well as flood ones by extending the measurable range of velocity. A newly developed high-performance MWSCM for general use can measure the velocity range of 0.03-20.0 m/s from flood flows to normal flows, whereas MWSCM for floods can measure the velocity range of 0.5-10.0 m/s. The improvement of antenna isolation between transmitter and receiver to block the inflow of transmitted singals to receiver and the improvement of phase noise of oscillator are necessary for detecting low velocity with MWSCM technology. Separate type antenna of transmitting and receiving signals is developed for isolation enhancement and phase locked loop synthesizer as an oscillator is applied to high-performance MWSCM for general use. Microwave frequency of 24 GHz is applied to the new MWSCM rather than 10 GHz to make the new MWSCM small and light for convenient use of it at fields. Improvement requests on MWSCM for floods-stable velocity measurement, self test, low power consumtion, and waterproof and dampproof-from the users of it has been reflected on the development of the new version of MWSCM.

Effect of long-term organic matter application on physico-chemical properties in rice paddy soil -2. The effect of some physical properties of paddy field by the long-term application of rice straw and compost (논토양(土壤)의 이화학적(理化學的) 성질(性質)에 미치는 유기물(有機物)의 연용효과(蓮用效果) -II. 생고(生藁) 및 퇴비(堆肥) 연용(蓮用)이 논토양(土壤)의 몇가지 물리적(物理的) 성질(性質)에 미치는 영향(影響))

  • Yoo, Chul-Hyun;Kim, Jong-Gu;Park, Keong-Ho;Kim, Seong-Jo
    • Korean Journal of Soil Science and Fertilizer
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    • v.21 no.4
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    • pp.373-379
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    • 1988
  • This experiment was carried out to investigate the effects of long-term applications of rice straw and compost on the physical and mechanical properties of paddy fields and the yearly variation of rice yield in Fluvio-Marine plain of Jeonbug series. Amounts of rice straw and compost applied in this experiment were 500kg/10a, 1,000kg/10a respectively, and the nitrogen levels were 0, 15 and 20kg/10a. This experiment were continued for 9 years from 1979 to 1987. The results are summarized as follows: 1. Clay and silt ratios were decreased but versa in sand ratio, by the long-term application of rice straw and compost. 2. Bulk density in the long-term application of organic matter was lower in surface soil of non-application than nitrogen application (15kg/10a) and in rice straw than compost. 3. Solid ratio went down, but liquid and gaseous ratio went up especially, by organic matter application liquid ratio were increased by compost and gaseous ratio were increased by in rice straw. 4. Aggregates of bigger than 2mm were increased by long-term application of organic matter, and the effects was better in rice straw than compost. Accumulative aggregate of 2mm was 66.5% in nitrogen of 15kg/ 10a with rice straw, which showed the increase of 9.1% in comparison with the non-application of nitrogen and organic matter. 5. Liquid limit, plastic limit and plastic index were high in order of rice straw, compost and control, and liquid index was lower in compost than in rice straw. 6. Cole value was higher in vertical than horizontal and highest in the application of rice straw with nitrogen of 15kg/10a. Cone and shearing resistance were lowest in the application of rice straw with nitrogen. In total vertical pressure friction was higher in the long-term application of organic matter than control. 7. The change of yield index was higher in the long-term application of compost than rice straw in non-nitrogen and it showed the yearly competitive variation between the long-term application of compost and rice straw in nitrogen of 10kg/10a. In nitrogen application of 20kg/10a, it was increased from 6th year by rice straw application.

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Improvement of Mid-and Low-flow Estimation Using Variable Nonlinear Catchment Wetness Index (비선형 유역습윤지수를 이용한 평갈수기 유출모의개선)

  • Hyun, Sukhoon;Kang, Boosik;Kim, Jin-Gyeom
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.5
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    • pp.779-789
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    • 2016
  • The effective rainfall is calculated considering the soil moisture. It utilizes observed data directly in order to incorporate the soil moisture into the rainfall-runoff model, or it calculates indirectly within the model. The rainfall-runoff model, IHACRES, used in this study computes the catchment wetness index (CWI) first varying with temperature and utilize it for estimating precipitation loss. The nonlinear relationship between the CWI and the effective rainfall in the Hapcheondam watershed was derived and utilized for the long-term runoff calculation. The effects of variable and constant CWI during calibration and validation were suggested by flow regime. The results show the variable CWI is generally more effective than the constant CWI. The $R^2$ during high flow period shows relatively higher than the ones during normal or low flow period, but the difference between cases of the variable and constant CWI was insignificant. The results indicates that the high flow is relatively less sensitive to the evaporation and soil moisture associated with temperature. On the other hand, the variable CWI gives more desirable results during normal and low flow periods which means that it is crucial to incorporate evaporation and soil moisture depending on temperature into long-term continuous runoff simulation. The NSE tends to decrease during high flow period with high variability which could be natural because NSE index is largely influenced by outliers of underlying variable. Nevertheless overall NSE shows satisfactory range higher than 0.9. The utilization of variable CWI during normal and low flow period would improve the computation of long-term rainfall-runoff simulation.

The Effect of Platelet Derived Growth Factor - BB Loaded Chitosan/Calcium Metaphosphate on Bone Regeneration (혈소판유래성장인자를 함유한 Chitosan/Calcium Metaphosphate의 골조직재생효과에 관한 연구)

  • Lee, Seung-Yeol;Seol, Yang-Jo;Lee, Yong-Moo;Lee, Ju-Yeon;Lee, Seung-Jin;Kim, Suk-Young;Ku, Young;Rhyu, In-Chul;Han, Soo-Boo;Choi, Sang-Mook;Chung, Chong-Pyoung
    • Journal of Periodontal and Implant Science
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    • v.31 no.1
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    • pp.1-23
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    • 2001
  • Chitosan is biodegradable natural polymer that has been demonstrated its ability to improve wound healing, and calcium metaphosphate(CMP) is a unique class of phosphate minerals having a polymeric structure. In this study, chitosan/CMP and platelet derived growth factor(PDGF-BB) loaded chitosan/CMP sponges were developed, and the effect of the sponges on bone regeneration and their possibility as scaffolds for bone formation by three-dimensional osteoblast culture were examined. PDGF-BB loaded chitosan/CMP sponges were prepared by freeze-drying of a mixture of chitosan solution and CMP powder, and soaking in a PDGF-BB solution. Fabricated sponge retained its 3-dimensional porous structure with $100-200\;{\mu}m$ pores. The release kinetics of PDGF-BB loaded onto the sponge were measured in vitro with $^{125}I-labeled$ PDGF-BB. In order to examine their possibility as scaffolds for bone formation, fetal rat calvarial osteoblastic cells were isolated, cultured, and seeded into the sponges. The cell-sponge constructs were cultured for 28 days. Cell proliferation, alkaline phosphatase activity were measured at 1, 7, 14 and 28 days, and histologic examination was performed. In order to examine the effect on the healing of bone defect, the sponges were implanted into rat calvarial defects. Rats were sacrificed 2 and 4 weeks after implantation and histologic and histomorphometrical examination were performed. An effective therapeutic concentration of PDGF-BB following a high initial burst release was maintained throughout the examination period. PDGF-BB loaded chitosan/CMP sponges supported the proliferation of seeded osteoblastic cells as well as their differentiation as indicated by high alkaline phosphatase activities. Histologic findings indicated that seeded osteoblastic cells well attached to sponge matrices and proliferated in a multi-layer fashion. In the experiments of implantation in rat calvarial defects, histologic and histomorphometric examination revealed that chitosan/CMP sponge promoted osseous healing as compared to controls. PDGF-BB loaded chitosan/CMP sponge further echanced bone regeneration. These results suggested that PDGF-BB loaded chitosan/CMP sponge was a feasable scaffolding material to grow osteoblast in a three-dimentional structure for transplantation into a site for bone regeneration.

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