• Journal of the Mineralogical Society of Korea
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• v.23 no.4
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• pp.297-303
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• 2010

We report the particle-size distribution and comminution charactersitics of dolomite depending upon crushing equipment (hammer crusher and roll crusher) and crushing circuit (open and closed). The quantity of fine particles (< 100 mesh) produced by hammer crusher was 34 wt.% which is about three times that by roll crusher. The quantity of 14~25 mesh size fraction by roll crusher was 20 wt.% higher than that produced by hammer crusher. 80 wt.% of the crushing products by hammer crushing was under 35 mesh in size, while the particles produced by roll crushing were relatively coarse. The particle size of both the hammer and roll crushers decreased by employing closed crusing circuit in comparison to open circuit. Products of required particle-size were obtained effectively depending on appropriate crushing equipment and crushing circuit.

• Tunnel and Underground Space
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• v.13 no.6
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• pp.444-454
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• 2003

Rock fragmentation technique by cutter penetration has widely been used in the mechanical tunnel excavation. Microcracks propagate and interact because of locally concentrated high stress induced by cutter penetration. which is caused by heterogeneity of rocks. In this study Weibull distribution function and degradation index are used to consider the strength heterogeneity of a rock and the degradation of rock properties after failure. Through the numerical analyses, it is shown that the lateral pressure has an important influence on the rock fragmentation. In the single cutter penetration, large chips are formed as lateral pressure increase. The cutter spacing is also an important factor that affects the rock fragmentation in the double cutter penetration. The fragmentation efficiency of the double cutter penetration is better when cutter spacing is 70 mm than 40 mm and 100 mm. From the results, it is expected that this study can be applied to a TBM tunnel design by understanding of chipping process and mechanism of rock due to cutter penetration.

• Food Science of Animal Resources
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• v.26 no.2
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• pp.263-268
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• 2006

Probiotics including Lactobacillus acidophilus, refer to a group of nonpathogenic organisms that protect the human host against gastrointestinal(GI) infections by pathogenic bacteria such as Shiga toxin-producing E. coli(STEC). In the study, the inhibitory effects of STEC ATCC 43894 adhesion by L. acidophilus A4 was investigated on the HT-29 epithelial cells. Specific proteins regulated by cell Iysates of L. acidophilus A4 on STEC ATCC 43894 were also characterized by proteomic analysis. Both cell mass and Iysate of L. acidophilus A4 have exhibited the profound inhibitory activity on the HT-29 cells(about 1.5 log scale reduction). Two-dimensional gel electrophoresis(2-DE) revealed seven proteins that were up-regulated by cell Iysates of L. acidophilus A4 and three proteins that were down-regulated. In addition, three protein spots were only detected in the presence of cell Iysates. These results suggest that inhibitory effects of STEC adhesion by L. acidophilus may be due to the regulation of specific protein of STEC.

• Korean Journal of Food Science and Technology
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• v.40 no.1
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• pp.82-87
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• 2008

Atopic dermatitis (AD) is characterized by chronic relapsing inflammation and is associated with hyper-production of immunoglobulin E (IgE). Recent studies have suggested that one of the treatments to alleviate symptoms of AD could be a supplementation of probiotics, Lactobacillus, Rhamnosus, Bifidus, etc. The purpose of this study was to evaluate the effects of probiotics on immune parameters in NC/Nga mice treated with 1-chloro-2,4-dinitro-benzene (DNCB). To induce atopic dermatitis, DNCB was treated to the back of mice for 2 weeks. Then, NC/Nga mice were divided into the four experimental groups randomly. Probiotics fragment, probiotics with other complex (Lactobacillus rhamnosus GG, Bifidobacterium lactis Bb-12LbL, L. plantarum K8, L. plantarum K8 fragment, ${\gamma}$-linolenic acid), antihistamine, and distilled water were administrated orally to the NC/Nga mouse for 4 weeks of experimental period. The groups were probiotics fragment group (DPF), probiotics with other complex group (DPOC), antihistamine group (DAH) and distilled water group (DDW) as a control group. The levels of serum IgE, interlukin-4 (IL-4), interlukin-5 (IL-5), interferon-gamma (IFN-${\gamma}$) and spleenocyte IgE were measured. The levels of serum IgE were significantly different among the four experimental groups. Before the treatment, there was no differences among the groups. However, from the first through the third week of the treatments, the levels of serum IgE in the probiotics (DPF, DPOC) and antihistamine (DAH) groups were lower than those of control group (p < 0.05). The levels of serum IL-4 of DPOC group was significantly lower than that of control group (p < 0.05) and serum IL-5 levels of DPF, DPOC, and DAH groups were significantly lower than that of control group. The levels of serum IFN-${\gamma}$ were not different among the four experimental groups. The levels of serum IgE in supernatant of spleen lymphocytes were not significantly different among the groups. These results suggest that probiotics supplementation showed partial effectiveness in the DNCB treated NC/Nga mice via modulation of IgE level and IL-4, IL-5 production. Based on these findings, probiotics exhibited the inhibitory effect via IL-4 production thereby inhibited the production of IgE in atopic animal model NC/Nga mice.

• Journal of The Geomorphological Association of Korea
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• v.15 no.2
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• pp.11-24
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• 2008

Stratified slope was formed on the SSE-facing slope in the southwest region of Haenam, South Korea. Field and laboratory investigations into the geomorphology and sedimentology of stratified slope deposit that is inactive. Outcrops of this deposit show an alteration of coarse debris-supported matrix and tiny debris-supported matrix layers. Sedimentological analysis(particle-size analysis) indicates that this deposit is not fluvial process or only gravitation like rock-fall. Many clasts and fine materials on the slope is supposed to be product by congelifraction under Pleistocene periglacial climatic environment. Also The processes responsible for the genesis of this deposit probably are to move downward by gelifluction and to remove fine materials by slope wash in thawing cycle and in situ debris congelifraction on gelifluction slope. Now It is impossible to account for the time range of genesis(diurnal, seasonal). In conclusion, this stratified slope formed in cold and humid periglacial environmental in pleistocene, therefore, this slope is a periglacial relic landform, indicates that in south korea there was a cold and humid paleo-climate such as periglacial environmen.

• Geotechnical Engineering
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• v.11 no.3
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• pp.139-162
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• 1995

The possibility of the development of gas driven hydrofractures at the Waste Isolation Pilot Plant(WIPP) is investigated through analytical and numerical calculations and through laboratory experiments. First, an investigation of the chemical reactions involved shows that a large volume of gas could potentially be generated through the oxidation of iron in the waste. Simple ground water'flow calculations then show that unless regions of high permeability has been created, this gas volume will build up the pressure high enough to cause tensile damage in the horizontal planes of weakness or in the halite itself. The analytical calculations were performed using the concepts of linear elastic fracture mechanics and the numerical calculations were done using the finite element method. Also, laboratory tests were conducted to illustrate possible failure mechanisms. It is possible that after growing horizontal crack in the weaker anhydride layer, the crack could break out of this layer and propagate upward into the halite and toward the ground surface at an inclined argle of around 53$^{\circ}$ above horizontal. To prevent this latter phenomenon the anhydrite must have a fracture toughness less than 0.5590 times than that of the halite. Through the tests, three types of crack(radial vertical cracks, horizontal circular cracks and cone -shaped cracks) were observed.

• Economic and Environmental Geology
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• v.46 no.4
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• pp.359-373
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• 2013

Shale is considered as a source rock for conventional oil and gas exploration and development because shale is fine-grained detrital sedimentary rock which can preserve the organic matter better. Shale has a good sealing capacity for the petroleum trap due to its low permeability. Commercial recoveries of gas from shale in the North America based on the development of technologies of horizontal drilling and hydraulic fracturing reveal that shale also function as a effective reservoir rock. Geochemical techniques to evaluate generation potential of the hydrocarbons from organic matter in the source rocks can be applied for the exploration of the shale gas resources. To evaluate shale gas resources, it is important to understand various geochemical processes and shale characteristics controlling generation, storage and estimation of shale gas reserves. In this paper, the generation mechanism of the oil and gas from organic matter is reviewed, and geochemical techniques which can be applied for the evaluation and characterization of shale gas are introduced.

• Tunnel and Underground Space
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• v.23 no.6
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• pp.457-469
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• 2013

We have analyzed the regional in-situ stress pattern using 460 stress measurement data at about 100 test sites in Korea, and suggested correlation equations of stress-depth and stress ratio-depth. We made Korea Stress Map(KSM) as in-situ stress fields of the Korean peninsula, combining with a paleo-stress analysis according to the geological period and a stress estimation from focal mechanism. We confirmed the reliability and applicability of correlation equations derived in this study, comparing with worldwide stress-depth patterns, and also estimated the pattern of in-situ stress fields of north-eastern Asia including Korea, China and Japan, comparing with World Stress Map.