• Journal of the Korean Institute of Gas
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• v.24 no.6
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• pp.34-46
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• 2020

In order to supply stable natural gas in the future, it is necessary to forecast the demand in advance and secure the quantity of supply. In this paper, we propose a method of estimating the demand function of industrial natural gas, which is the core of the increase of domestic natural gas demand in the future. The cross-sectional data of 304 domestic industries were used to estimate the demand function of the industrial natural gas, and the effect of industry specific characteristics such as capital investment, manufacturing cost. Finally, the least absolute deviation estimation method which is robust to outliers and does not assume the homogeneity of the error term and the normality, And the results were derived. In addition, the economic value of industrial city gas was estimated using the price elasticity of industrial city gas. Therefore, it can be seen that the continuous expansion and supply of city gas to the industrial sector is beneficial at the national level, and the government needs to promote expansion through the industrial city gas support policy.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.35 no.6
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• pp.367-374
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• 2022

This papter presents the use of the automatic differential method based on the backpropagation method to obtain the design sensitivity and its application to topology optimization considering the stress constraints. Solving topology optimization problems with stress constraints is difficult owing to singularities, the local nature of stress constraints, and nonlinearity with respect to design variables. To solve the singularity problem, the stress relaxation technique is used, and p-norm for stress constraints is applied instead of local stresses for global stress measures. To overcome the nonlinearity of the design variables in stress constraint problems, it is important to analytically obtain the exact design sensitivity. In conventional topology optimization, design sensitivity is obtained efficiently and accurately using the adjoint variable method; however, obtaining the design sensitivity analytically and additionally solving the adjoint equation is difficult. To address this problem, the design sensitivity is obtained using a backpropagation technique that is used to determine optimal weights and biases in the artificial neural network, and it is applied to the topology optimization with the stress constraints. The backpropagation technique is used in automatic differentiation and can simplify the calculation of the design sensitivity for the objectives or constraint functions without complicated analytical derivations. In addition, the backpropagation process is more computationally efficient than solving adjoint equations in sensitivity calculations.

• The Korean Journal of Nuclear Medicine
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• v.34 no.1
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• pp.55-61
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• 2000

Purpose: We performed this study to evaluate the changes of gallbladder ejection fraction (GBEF) in diabetic patients with or without autonomic neuropathy. Materials and Methods: This study included 37 diabetic patients (25 women, 12 men, mean age 51 years) and 24 normal controls (10 women, 14 men, mean age 38 years). After intravenous injection of 185 MBq of $^{99m}Tc$-DISIDA, serial anterior abdominal images were acquired before and after fatty meal. Regions of interest were applied on gallbladder and right hepatic lobe on 60 and 90 minute images to calculate GBEF. Results: GBEF was significantly reduced in diabetes with autonomic neuropathy ($43{\pm}12.3%$) and without autonomic neuropathy ($57.5{\pm}13.2%$) compared with normal controls ($68{\pm}11.6%$, p<0.05). And also, GBEF was significantly reduced in diabetes with autonomic neuropathy compared with diabetes without autonomic neuropathy (p<0.05). Fasting blood glucose level, age, sex, hemoglobin Alc, body mass index, serum lipid level were not different in these two diabetic patient groups (p>0.05). When 50.2% of GBEF was used as the criteria for diabetic autonomic neuropathy, the sensitivity and specificity were 80%, 76.5%, respectively. The area under receiver operating characteristic curve was 0.846. Conclusion: GBEF of diabetic patients with autonomic neuropathy was significantly reduced than that of diabetic patients without autonomic neuropathy.

• Bulletin of the Society of Naval Architects of Korea
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• v.26 no.2
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• pp.49-63
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• 1989

Wave drift forces which are small in magnitudes compared to the first order wave exciting forces can cause very large motion of a vessel in waves. In this paper a theoretical and experimental analysis is made of the mean and slowly varying wave dirft forces on the semi-submersible platform. Theoretical calculations are performed by using near field method with three dimensional diffraction theory and model tests are carried out in regular and irregular waves with a 1/60 semi model. Test results are compared with theoretical calculations and the mooring spring effects in the test are discussed.

• Bulletin of the Society of Naval Architects of Korea
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• v.26 no.4
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• pp.3-13
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• 1989

In recent towing tank experiments, it has been observed that a ship moving near the critical speed $\sqrt{gh}$(g=gravitational acceleration, h=water depth) radiates solitons upstream in an almost periodic manner. As a ,consequence, the ship experiences considerable changes in resistance, trim and sinkage, or better known as squat. Mei and Choi(1987) developed a nonlinear theory for a slender ship by using the method of matched asymptotic expansions. For a certain class of channel width and ship slenderness, they found that the waves generated can be described by an inhomogeneous Korteweg-de Vries(KdV) equation. The leading-order solution properly predicts solitons propagating upstream, but it fails to render three-dimensional waves in the wake. In this paper a new approach has been made by choosing a different class of channel width and ship slenderness. The wave equation in the farfield turns out to be a homogeneous Kadomtsev-Petviashvili(KP) equation, which predicts solitons upstream and three-dimensional waves in the wake. Numerical results for the wave resistance, sinkage and trim reflect the experimentally identified phenomena.

• Parasites, Hosts and Diseases
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• v.32 no.1
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• pp.53-56
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• 1994

A case of gastric anisaklasis due to the larva of Pseunotewqnova decipiens was confirmed by gastroendoscoplc examination In April 23, 1991. The patient, residing In Pusan, was a 42-year-old housewife, who complained of severe epigastric pawn and recalled that the symptom suddenly attacked her about 6 hours after eating raw Sebqstes inermis. In the gastroendoscopic examination performed about 9 hours after the onset of the symptom, a long whitish nematode larva penetrating the gastric mucosa in the greater curvature of mid-body was found and removed with a biopsy forcep. The nematode was $29.73{\times}0.94mm$ in size, had an intestinal cecum reaching over mfd-level of the ventnculus and was identified as the 4th stage larva of f decfpiens.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.775-779
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• 2009

최근 이상기후 및 국지성 돌발호우 등 여러 가지 형태의 예기치 못한 기상이변으로 인하여 매년 수재해는 빈번히 발생하고 있으며, 이를 위해 하천에서 실시간으로 신속하고 안정성있는 수리학적 하도추적모형의 구축은 지속적으로 연구해야 할 사항이다. 현재 주요 수계 홍수통제소에서는 홍수예보를 위해 주로 수리학적 및 수문학적 모형이 병행되어 적용되고 있으나, 한강과 금강하류를 제외한 나머지 수계에서는 아직까지 개념적 수문학적 모형만을 이용하여 홍수예보를 수행하고 있는 실정이다. 그러나, 신속하고 안정적인 수문학적 모형이 가지고 있는 몇가지 장점에도 불구하고, 실시간 분석 및 신속한 상황대처를 위해서는 정교한 하천흐름해석 기술인 수리학적분석이 반드시 필요하다. 그러나, 대부분의 모형운영자가 직면하게 되는 수리학적 하도추적모형에서 발생하는 수치적 불안정성인 발산의 문제점은 상당한 어려움으로 작용하고 있다. 이는 다양한 원인들이 있을 수 있으나, 대표적으로 단면의 불규칙성을 고려할 수 있다. 실제단면들을 모형에 반영할 때 수치계산의 과정 중에 급확대/급축소/특이단면에 따른 잦은 발산이 발생하게 되며, 이를 방지하기 위해서 단면의 보간 및 평활화 작업 등을 수행하게 된다. 이때 단면의 형상을 최대한 반영한 보간 및 평활화 작업이 되지 않으면, 물리적 개념이 무시된 비합리적인 계산이 수행될 수 있다. 발산의 요인을 제거한 최적의 단면형태를 선정하는 것은 모형의 안정성을 확보하는 데 중요한 요인이 된다. 또한 모형수행에 있어 발산의 요인으로서 하구와 만나게 되는 지점에서의 경계조건으로서 조위영향이 있다. 수리학적 하도추적모형의 중요한 요인인 하구에서의 흐름을 조위와 연계하여 가장 합리적인 하류 경계조건을 제시하는 것이 모형의 발산 방지 및 정확도를 향상시키는데 중요한 인자로 작용하고 있다. 본 연구에서는 이와 같은 수리학적 하도추적모형의 안정성 검증을 위하여, 아직까지 수리학적 하도추적모형이 구축되어 있지 않는, 금강상류구간인 용담댐$^{\sim}$대청댐구간을 설정하여 수리학적 모형의 입력자료를 구축하고, 그에 따른 영향검토를 지속적으로 추진할 계획이다. 대상구간에서 향후 검증될 다양한 수리학적 안정화 기술은 향후 타 수계에서 적용시, 신속하고 합리적인 입력자료 구축에 많은 도움을 줄것이며, 현재 하천에서 발생하는 계산의 불안정성을 빠르게 수정하는 것이 가능하다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.274-274
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• 1994

본 연구에서는 토끼신장 근위세뇨관 일차배양세포에서 브라디키닌의 생리작용이 phospholipase D (PLD)에 의해 매개되는지를 살펴 보기위해 PLD 효소반응의 특이한 성질인 transphosphatidylation 반응의 생성물인 phosphatidylethanol (PEth) 의 세포내 양을 측정함으로 PLD 효소의 관련성을 규명할 수 있었다. 시간경과에 따른 phosphatidic acid (PA) 및 diacylglycerol (DAG) 의 생성을 살펴본 결과 PA가 DAG보다 먼저 생성되어 최고치 (30초)에 도달하였고 DAG는 1분이후부터 5분까지 서서히 생성되는 양상을 나타내었다. 또한 0.5에서 5％까지의 에탄올 존재하에 PA 및 PE소 생성량을 비교해본 결과 에탄올량이 증가함에 따라 PA는 감소하는 반민 PEth 의 생성은 계속 증가하였다. 한편 브라디키닌 농도 변화 실험에서는 브라디키닌농도가 증가함에 따라 PA 및 PEth 둘다 생성이 증가되었다. 이러한 결과로부터 토끼신장 근위세뇨관 세포막에 존재하는 브라디키닌수용체는 브라디키닌에 의해 activation 시 PLD를 직접적으로 활성화시켜 그들의 작용을 세포내로 전달한다는 사실을 알 수 있었다. 또한 PLD 효소활성의 activator로 수용체효능 제외에 칼슘이온, protein kinase C (PKC) 등이 몇몇 다른 실험에 의해 밝혀져 있고, G protein 역시 PLD 효소 활성을 조절하는 역할이 있음이 알려졌다. calcium ionophore 및 칼슘채널길항제인 verapamil을 이용한 실험에서 우리는 브라디키닌의 PLD 활성화는 칼슘이온에 의존적인 경로 및 비의존적인 경로가 같이 존재함을 알수 있었다. 또한 브라디키닌의 PLD 활성화기전이 PKC 의존적인지를 살펴보기위해 PKC activator(PMA) 및 inhibitor (staurosporine)를 이용한 실험에서 브라디키닌은 신장세포에서 PKC를 통하여 PLD를 활성화시킴으로 신호전달을 하는 것으로 추측되었다. 마지막으로 가수분해안되는 G protein 유도체인 GTPrS 및 G protein 활성물질 NaF, 백일해독소등을 이용한 실험에서 G protein 의 PLD 조절활성을 확인할 수 있었다.

• Journal of the Korean Society of Groundwater Environment
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• v.2 no.2
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• pp.49-57
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• 1995

Areas of Chungyang in Chungcheongnamdo, Cheju island and Georgia in U.S.A. were selected to calculate their groundwater ages and dispersion parameters using tritium. Piston flow model, Completely mixing model and Dispersion binomial model which calculate men residence times, and Dispersion normal model and Dispersion model(C$\_$FF) which calculate mean residence times and dispersion parameters simultaneously were applied. Since the input data, tritium concentrations of rainwaters, lack in part, tritium input function was prepared using the correlation of tritium concentrations of rainwaters of Pohang, Korea and Ottawa, Canada. Similar results of PFM and DBM reflect the intrinsical similarity of two models, assumption of low dispersion. The ages of sites of showing relatively higher tritium concentrations than other sites in the sam, region were not calculated by CMM. Since the calculations of DNM and DM(C$\_$FF/) provide the combination of wide ranges of parameters and groundwater ages, the ranges of dispersion parameters were narrowed down under the assumption that ages calculated by PFM and DBM are correct. Since large variation of tritium concentrations of outflows in a same region may reflect the different characteristics of each groundwater flow regime, using only one specific model on a whole region is not recommended.

• Journal of Chest Surgery
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• v.31 no.3
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• pp.329-335
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• 1998

A 55-year-old male was admitted to our hospital complaining of chest discomfort, dysphagia and severe pain on swallowing. Esophageal manometry showed that there was no relaxation of lower esophageal sphincter to swallowing. There was double barrelled esophagus or mucosal stripe appearance on esophagogram. Endoscopy revealed an appearance as if an esophago-tracheal fistula had been made at the level of the upper thoracic esophagus. Also, two slit-like mucosal tears was seen on the lower esophagus. There after, fasting and total parenteral nutrition for several weeks failed to bring about any changes in his symptoms. So, as treatment, primary closure of the upper opening of the false lummen was performed under general anesthesia. Soon after the surgical procedure, the patient's symptoms were improved except for mild dysphagia. He was discharged after oral intake had been juduciously commenced with fluids and soft diet subsequently. During follow-up in out-patient department, he had no specific symptoms including fever or dysphagia and massive dissection of the esophagus was improved on esophagogram. We report the experience of a case of spontaneous submucosal dissection of the esophagus which required conservative and surgical management