• Title/Summary/Keyword: 특이성 지수

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Relationship between Carotid Intima Media Thickness and Appendicular Skeletal Muscle Index according to Gender (성별에 따른 경동맥 내중막두께와 사지근육량지수와의 관련성)

  • Yang, Sung-Hee;Lee, Hee-Jeong
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.309-317
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    • 2022
  • It is reported that social distancing caused by the corona pandemic has resulted in a decrease in physical activity, and a decrease in muscle mass due to this increases the risk of vascular disease. Therefore, in this study, the risk of carotid intima media thickness was evaluated by measuring the thickness of CIMT, and the differences in variables according to gender were analyzed. From January 2022 to May 2022, a total of 220 people (121 males, 99 females) who performed blood tests, carotid ultrasound, and body composition analysis among those who visited the health check-up center of Busan H Hospital were included in this study. Significant differences in risk factors according to gender were analyzed using the chi-square test. The cut-off values of variables that can predict the risk of carotid intima media thickness were calculated, and the accuracy was evaluated by calculating the area under the curve, sensitivity, and specificity. As a result of the difference analysis, the higher the total cholesterol in men and the appendicular skeletal muscle index in women, the higher the risk of carotid intima media thickness. The cut-off value for predicting the risk of carotid intima media thickness was calculated to be greater than 199 mg/dL of total cholesterol in the male group and less than 5.9 kg/m2 of the appendicular skeletal muscle index in the female group. As a result of this study, the higher the total cholesterol in men and the lower the appendicular skeletal muscle index in women, the higher the risk of increased CIMT. Therefore, in women, the appendicular skeletal muscle index is expected to serve as an indicator to predict and prevent vascular changes at an early stage.

Morphological Characteristics and Genetic Diversity Analysis of Cultivated Sancho (Zanthoxylum schinifolium) and Chopi (Zanthoxylum piperitum) in Korea (국내 재배지의 산초(Zanthoxylum schinifolium)와 초피(Zanthoxylum piperitum)의 형태학적 특성과 유전적 다양성)

  • Ryu, Jaihyunk;Choi, Hae-Sik;Lyu, Jae-il;Bae, Chang-Hyu
    • Korean Journal of Plant Resources
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    • v.29 no.5
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    • pp.555-563
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    • 2016
  • The morphological characteristics and genetic relationships among 32 germplasms of Zanthoxylum schinifolium and Zanthoxylum piperitum collected from two farms in Korea were investigated. The traits with the most variability were seed color, leaf size, and spine size. The intraspecific polymorphism of Z. schinifolium and Z. piperitum was 96.5% and 60.3%, respectively. The genetic diversity and Shannon’s information index values ranged from 0.11 to 0.33 and 0.19 to 0.50, with average values of 0.26 and 0.42, respectively. Two ISSR primers (UBC861 and UBC862) were able to distinguish the different species. The genetic similarity matrix (GSM) revealed variability among the accessions ranging from 0.116 to 0.816. The intraspecific GSM for Z. schinifolium and Z. piperitum was 0.177-0.780 and 0.250-0.816, respectively. The GSM findings indicate that Z. schinifolium and Z. piperitum accessions have high genetic diversity and possess germplasms qualifying as good genetic resources for cross breeding. The clustering analysis separated Z. schinifolium and Z. piperitum into independent groups, and all accessions could be classified into three categories. Z. Schinifolium var. nermis belonged to independent groups. Comparison of the clusters based on morphological analysis with those based on ISSR data resulted in an unclear pattern of division among the accessions. The study findings indicate that Z. schinifolium and Z. piperitum accessions have genetic diversity, and ISSR markers were useful for identifying Z. schinifolium and Z. piperitum.

Engineering Properties of Red Shale and Black Shale of the Daegu Area, Korea (대구지역 적색 셰일과 흑색 셰일의 공학적 특성)

  • Kwag, Seong-Min;Jung, Yong-Wook;Kim, Gyo-Won
    • The Journal of Engineering Geology
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    • v.23 no.4
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    • pp.341-352
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    • 2013
  • The physical and mechanical properties of red shale and black shale exposed in the Daegu area were investigated in tests conducted to determine unit weight, absorption ratio, porosity, ultrasonic velocity, unconfined compressive strength, point load strength, slake durability index, and deterioration characteristics. XRD, XRF, and SEM analyses were also performed on the shale specimens. While the unit weights of the two shales were similar, the absorption ratio and porosity were higher in the red shale than in the black shale. Despite the higher porosity of the red shale, the ultrasonic velocity, compressive strength, and point load strength were higher in the red shale, which is an unexpected result that may be due to the presence of fine laminations in the black shale. The deterioration rate, as determined from the point load strength and the slake durability index, increased with increasing immersion time and with the acidity of the immersion liquid. The deterioration rate was higher for the red shale than for the black shale because of the higher porosity of the former.

Present State and Conservation Counterplan for the Wetlands of the Tributaries around Namgang-River (남강 주변 습지의 보전 현황과 보전 대책)

  • Ha, Hye-Jeong;Oh, Kyung-Hwan
    • Journal of Wetlands Research
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    • v.12 no.3
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    • pp.21-37
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    • 2010
  • The abiotic factors and the vegetation naturalness of the 13 tributary wetlands around Namgang-River were assessed to investigate the present state and to present the conservation counter plan for the wetland ecosystem of the tributaries. Assessment indices for the abiotic factors were estimated based on the dominant land use types of the riparian zone, ecological function of the upper levee, levee slope structure, artificiality and utilization intensity of the waterfront, artificiality of the revetment structure, diversity of the substrate, and severance of the transverse. The assessment index of Omi-cheon is the highest among 13 tributaries. The second was Banseong-cheon and third was Hyangyang-cheon, followed by Nabul-cheon and Yeongcheon-gang and Sugok-cheon, Jungchon- cheon, and Daegok-cheon in their order and Munsan-cheon got the lowest assessment index. Assessment indices for the vegetation naturalness were estimated based on the vegetation diversity, exotic species dominance, annual herb dominance, naturalness and peculiarity of the vegetation, and species diversity. The assessment index of Omi-cheon is the highest among 13 tributaries. The second was Sugok-cheon and third was Banseong-cheon, followed by Yeongcheon-gang, Jungchon- cheon, Jinae-cheon, Nabul-cheon, and Jisu-cheon in their order, and Yonga-cheon got the lowest assessment index. The grades of the stream naturalness were estimated based on the the naturalness indices for the abiotic factors and the vegetation naturalness. The grades of Omi-cheon is the highest among 13 tributaries as the grade I. Those of Banseong-cheon, Sugok-cheon, Yeongcheon-gang, Nabul-cheon and Jungchon-cheon, Hyangyang-cheon, Jinae-cheon, Jisu-cheon, Daegok-cheone, and Munsan-cheon and Doksan-cheon were grade II in their order, and Yonga-cheon got the lowest as the grade III. It was suggested that restoration of the simple and flat substrate, create the natural vegetation on the levee slope constructed with concrete or stone wall, and rehabilitation of the eco-bridge were demanded to improve the grades of the stream naturalness through the restoration of the tributaries for the diverse aquatic wildlife, high vegetation diversity and species diversity with the vegetation consisted of perennial herbs and trees.

Investigation into Crack-Tip Constraint of Curved Wide-Plate using Q-Stress (Q-응력을 이용한 휜 광폭평판 균열부 구속상태 변화 평가)

  • Lee, Hwee-Sueng;Huh, Nam-Su;Kim, Ki-Seok;Shim, Sang-Hoon;Cho, Woo-Yeon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.38 no.12
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    • pp.1441-1446
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    • 2014
  • In the present paper, the effects of the thickness and width of a curved wide-plate, the crack length, and the strain hardening exponent on the crack-tip constraint of the curved wide-plate were investigated. To accomplish this, detailed three-dimensional elastic-plastic finite element (FE) analyses were performed considering various geometric and material variables. The material was characterized by the Ramberg-Osgood relationship, and the Q-stress was employed as a crack-tip constraint parameter. Based on the present FE results, the variations in the Q-stress of the curved wide-plate with the geometric variables and material properties were evaluated. This revealed that the effect of out-of-plane constraint conditions on the crack-tip constraint was closely related to the in-plane constraint conditions, and out-of-plane constraint conditions affected the crack-tip constraint more than in-plane constraint conditions.

Multifractal Stochastic Processes and Stock Prices (다중프랙탈 확률과정과 주가형성)

  • Rhee, Il-King
    • The Korean Journal of Financial Management
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    • v.20 no.2
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    • pp.95-126
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    • 2003
  • This paper introduces multifractal processes and presents the empirical investigation of the multifractal asset pricing. The multifractal stock price process contains long-tails which focus on Levy-Stable distributions. The process also contains long-dependence, which is the characteristic feature of fractional Brownian motion. Multifractality introduces a new source of heterogeneity through time-varying local reqularity in the price path. This paper investigates multifractality in stock prices. After finding evidence of multifractal scaling, the multifractal spectrum is estimated via the Legendre transform. The distinguishing feature of the multifractal process is multiscaling of the return distribution's moments under time-resealing. More intensive study is required of estimation techniques and inference procedures.

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The Usefulness of Integrated PET/CT to Distinguish between Benignancy and Malignancy in Solitary Pulmonary Nodule (고립성 폐결절의 악성 감별에서 Integrated PET/CT의 유용성)

  • Park, Won-Jong;Kim, Dong-Hee;Yu, Sung-Ken;Shin, Kyeong-Cheol;Chung, Jin-Hong;Lee, Kwan-Ho;Chun, Kyung-Ah;Cho, Ihn-Ho
    • Journal of Yeungnam Medical Science
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    • v.23 no.2
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    • pp.205-212
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    • 2006
  • Background: Malignant pulmonary nodules account for about 30 to 40 percent of solitary pulmonary nodules (SPN). Therefore, tissue characterization of SPNs is very important. Recently, PET/CT has been widely used for tissue characterization, and has become of importance. The purpose of this study was to compare and to assess multiple factors in PET/CT comparing benign and malignant nodules. Materials and Method: Nineteen patients with SPN underwent PET/CT and biopsy. The difference of standardized uptake value 1 (SUV1), standardized uptake value 2 (SUV2) and retention index in PET/CT between malignancy and benignancy were compared by Levene's test. Result: There were twelve malignant and seven benign nodules. SUV1 and SUV2 were significantly different between malignant nodule and benign nodule (p=0.006 and 0.022), but retention index was not significantly different between malignant nodule and benign nodule (p=0.526). By receiver-operating-characteristic (ROC) analysis, the sensitivity was 66.7% and the specificity was 71.4% at a cut off value of 5.40 in SUV1. The sensitivity was 75% and the specificity was 71.4% at cut off value of 7.45 in SUV2. Conclusion: There was a statistically significant difference in SUV1 and SUV2 between benign and malignant nodules. However, the cut off value of SUV1 and SUV2 by receiver-operating-characteristic (ROC) analysis was 5.40 and 7.45 which is different from previous studies. Therefore, studies on a larger sample of patients are required for confirmation.

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Validation of an analytical method of dieckol for standardization of Ecklonia cava extract as a functional ingredient (감태추출물의 기능성원료 표준화를 위한 지표성분 dieckol의 분석법 검증)

  • Xu, Yan;Kim, Eun Suh;Lee, Ji-Soo;Kim, Gun-Hee;Lee, Hyeon Gyu
    • Korean Journal of Food Science and Technology
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    • v.51 no.5
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    • pp.420-424
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    • 2019
  • An HPLC analysis method was developed and standardized for the detection of dieckol as a functional food ingredient in Ecklonia cava extracts. HPLC was performed using a Capcell Pak C18 column ($250{\times}4.6mm$, $5{\mu}m$) with a gradient elution of water and acetonitrile, both containing 0.1% (v/v) trifluoroacetic acid, at a flow rate of 1.0 mL/min at $25^{\circ}C$. The eluate was detected at 230 nm. For validation, the specificity, linearity, accuracy, precision, limit of detection (LOD), and limit of quantification (LOQ) of dieckol were measured. The calibration curve for the detection of dieckol had high linearity ($R^2=0.9994$), with LOD and LOQ values of 0.38 and $1.16{\mu}g/mL$, respectively. Recovery of the quantified compound ranged from 99.61 to 100.71%. The relative standard deviation values of the intra-day and inter-day precisions were less than 1.7 and 1.25%, respectively. These results indicate that the reported HPLC method is simple, reliable, and reproducible for the detection of dieckol in Ecklonia cava extracts.

Correlation between Body Fat Percent Estimated by Bioelectrical Impedance Analysis and Other Variable Methods (생체전기 저항법에 의한 체지방율과 다른 계측치간의 상관성 연구)

  • Yom, Hye Won;Kim, Su Jung;Whang, Il Tae;Hong, Young Mi
    • Clinical and Experimental Pediatrics
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    • v.46 no.8
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    • pp.751-757
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    • 2003
  • Purpose : Obesity is a significant health problem with medical and psychological consequences for children and adolescents. The purpose of this study was to assess the correlation between body fat percent using bioelectrical impedance(BI) and other variable methods. Methods : We measured height, weight, body mass index(BMI) and body fat percent by skinfold thickness(ST) and BI in 1,035(496 male; 539 female) children from seven to 18 years of age. The correlation coefficients between BI and each of the other different methods were obtained. The sensitivity and specificity to predict obesity by these several methods were studied. Results : Fat percent estimated by BI analysis and BMI showed a strong correlation(r=0.749). Fat percent estimated by BI analysis and ST showed a very strong correlation(r=0.835). At the 95th percentile cut-off point for BI, ST showed a sensitivity of 57.7%, and a specificity of 97.6% for estimating body fat. At the 95th percentile cut-off point for BI, BMI showed a sensitivity of 84.9%, and a specificity of 99.3% for estimating body fat. Conclusion : The fat percent estimated by BI analysis correlated strongly with ST or BMI. BI analysis is an objective and accurate method for estimating body fat in childhood obesity.

The $Fc{\gamma}$ receptor III genotype as a risk factor for aggressive periodontitis in Korean patients (한국인 급진성 치주염 환자의 위험요소로서 $Fc{\gamma}$ III 수용기의 유전형)

  • Kim, Myung-Hyun;Shin, Seung-Yun;Kim, Tae-Il;Seol, Yang-Jo;Lee, Yong-Moo;Rhyu, In-Chul;Chung, Chong-Pyoung;Han, Soo-Boo;Ku, Young
    • Journal of Periodontal and Implant Science
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    • v.36 no.1
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    • pp.113-123
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    • 2006
  • 연구배경 IgG에 대한 $Fc{\gamma}$ 수용기는 치주병인균에 대한 숙주 반응에 있어서 중요한 역할을 하는데, 이 중 $Fc{\gamma}RIIIa$는 NK 세포, 대식세포, 단핵구, ${\gamma}{\delta}T$세포에서 발현되며, EC2 도메인에서 158 아미노산 부위의 valine (V)-phenylalanine (F)의 유전자다형성을 보인다. $Fc{\gamma}RIIIb$는 특이적으로 중성구에 발현되는데, extracellular (ECl) Ig-like 도메인 내 4개의 아미노산 치환(substitutions)에 의한 NA1-NA2 유전자다형성을 보인다. 이 연구의 목적은 한국인에서 급진성 치주염 환자와 $Fc{\gamma}III$ 수용기의 유전자다형성과의 관련성을 알아보는 것이다. 연구방법 및 재료 치주적으로 건강한 90명 (대조군, 남자 64명, 여자 26명)과 서울대학교 치과병원 지주과에 내원하여 급진성 치주염으로 진단된 환자 43명 (aggressive periodontitis patients: AgP, 남자 30명, 여자 13명)을 대상으로 하였다. 모든 실험 대상자는 임상 실험에 대해 동의 하였고, 초진 시 전자 탐침(Florida Probe(R) Co. Gainesville, FL)을 이용하여 탐침 시 치주낭 깊이 (PPD), 임상부착수준 (CAL), 치태지수(PI), 탐침 후 출혈지수 (BOP)를 측정하였다. 또한 이들의 정맥혈에서 추출한 DNA를 PCR법, 전기영동법 등을 이용하여 $Fc{\gamma}RIIIa$, $Fc{\gamma}RIIIb$의 대립 유전자의 존재여부를 확인하였다. 이를 바탕으로 $Fc{\gamma}RIII$ 복합 유전형을 확인하여 각 군 간을 비교하였다. 연구 결과 1. $Fc{\gamma}RIIIa$에 대한 유전자다형성 연구 결과 대조군과 급진성 치주염 환자 군(AgP)사이에서는 대립 유전자 분포가 서로 유의성 있는 차이를 나타내었고 (P<0.05), $Fc{\gamma}RIIIb$에서는 유의성 있는 차이를 발견할 수 없었다. (P>0.05) 2. $Fc{\gamma}RIIIa$ 158F 대립형질이 급진성 치주염 환자에서 유의성 있게 많이 발견되어졌다. (P<0.05) 결론 이 연구를 통하여 $Fc{\gamma}RIIIa$ 유전자의 분석이 한국인의 급진성 치주염에 대한 감수성의 위험요소의 표지자로 활용할 수 있을 것으로 사료되며, 향 후 더 많은 환자를 대상으로 히는 추가 연구가 필요하다고 생각된다.