Validation of an analytical method of dieckol for standardization of Ecklonia cava extract as a functional ingredient
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Xu, Yan
(Department of Food and Nutrition, Hanyang University)
Kim, Eun Suh (Department of Food and Nutrition, Hanyang University) Lee, Ji-Soo (Department of Food and Nutrition, Hanyang University) Kim, Gun-Hee (Department of Food and Nutrition, Duksung Women's University) Lee, Hyeon Gyu (Department of Food and Nutrition, Hanyang University) |
1 | Ahn JH, Yang YI, Lee KT, Choi JH. Dieckol, isolated from the edible brown algae Ecklonia cava, induces apoptosis of ovarian cancer cells and inhibits tumor xenograft growth. J. Cancer Res. Clin. 141: 255-268 (2015) DOI |
2 | Ahn SM, Hong YK, Kwon GS, Sohn HY. Evaluation of in-vitro anticoagulation activity of 35 different seaweed extracts. J. Life Sci. 20: 1640-1647 (2010) DOI |
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4 | Heo SJ, Ko SC, Cha SH, Kang DH, Park HS, Choi YU, Kim DY, Jung WK, Jeon YJ. Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation. Toxicol. in vitro 23: 1123-1130 (2009) DOI |
5 | Hong JH, Son BS, Kim BK, Chee HY, Song KS, Lee BH, Shin HC, Lee KB. Antihypertensive effect of Ecklonia cava extract. Korean J. Pharmacogn. 37: 200-205 (2006) |
6 | Hwang HJ, Chen T, Nines RG, Shin HC, Stoner GD. Photochemoprevention of UVB-induced skin carcinogenesis in SKH-1 mice by brown algae polyphenols. Int. J. Cancer 119: 2742-2749 (2006) DOI |
7 | Hwang HJ, Chen T, Stoner GD, Lee KB, Yoo YC, Shin HC. Suppression of iNOS expression by phlorotannins in chronic exposure of skin to UVB radiation. Lab. Animal Res. 21: 385-389 (2005) |
8 | Jung SA, Kim KBWR, Kim MJ, Kim DH, Chan SW, Kim HJ, Jeong DH, Jeong HY, Kim TW, Cho YJ, Ahn DH. Trypsin inhibitory activity of water extracts from Ecklonia cava as affected by temperature and pH. J. Korean Soc. Food Sci. Nutr. 41: 840-845 (2012) DOI |
9 | Jung WK, Heo SJ, Jeon YJ, Lee CM, Park YM, Byun HG, Choi YH, Park SG, Choi IW. Inhibitory effects and molecular mechanism of dieckol isolated from marine brown alga on COX-2 and iNOS in microglial cells. J. Agr. Food Chem. 57: 4439-4446 (2009) DOI |
10 | Kang MC, Ahn G, Yang X, Kim KN, Kang SM, Lee SH, Ko SC, Ko JY, Kim D, Kim YT, Lee Y, Park SJ, Jee Y. Hepatoprotective effects of dieckol-rich phlorotannins from Ecklonia cava, a brown seaweed, against ethanol induced liver damage in BALB/c mice. Food Chem. Toxicol. 50(6): 1986-1991 (2012) DOI |
11 | Kim JY, Um MY, Yang HJ, Kim IH, Lee CH, Kim YT, Yoon MS, Kim YK, Kim JM, Cho SM. Method development and validation for dieckol in the standardization of phlorotannin preparations. Fish. Aquat. Sci. 19: 3 (2016) DOI |
12 | Kim YT, Lee JH, Ko JY, Oh JY, Sok CH, Hong JT, Jeon YJ. Isolation of eckol from Ecklonia cava via centrifugal partition chromatography (CPC) and characterization of it's antiinflammatory activity. Korean J. Fish Aquat. Sci. 48: 301-307 (2015) DOI |
13 | Yamashita H, Goto M, Matsui-Yuasa I, Kojima-Yuasa A. Ecklonia cava polyphenol has a protective effect against ethanol-induced liver injury in a cyclic AMP-dependent manner. Mar. Drugs 13: 3877-3891 (2015) DOI |
14 | Lee SH, Han JS, Heo SJ, Hwang JY, Jeon YJ. Protective effects of dieckol isolated from Ecklonia cava against high glucose-induced oxidative stress in human umbilical vein endothelial cells. Toxicol. in vitro 24: 375-381 (2010a) DOI |
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Lee SH, Park MH, Heo SJ, Kang SM, Ko SC, Han JS, Jeon YJ. Dieckol isolated from Ecklonia cava inhibits |
16 | Li Y, Qian ZJ, Ryu BM, Lee SH, Kim MM, Kim SK. Chemical components and its antioxidant properties in vitro: an edible marine brown alga, Ecklonia cava. Bioorgan. Med. Chem. 17: 1963-1973 (2009) DOI |
17 | Nshmiyumukiza O, Kang SK, Kim HJ, Lee EH, Han HN, Kim YH, Kim DK, Kim JH, Eom HE, Kim YM. Synergistic antibacterial activity of Ecklonia cava (Phaeophyceae: Laminariales) against Listeria monocytogenes (Bacillales: Listeriaceae). Fish. Aquat. Sci. 18: 1-6 (2015) DOI |
18 | Park EY, Kim EH, Kim MH, Seo YW, Lee JI, Jun HS. Polyphenolrich fraction of brown alga Ecklonia cava collected from Gijang, Korea, reduces obesity and glucose levels in high-fat diet-induced obese mice. Evid-Based Compl. Alt. http://dx.doi.org/10.1155/2012/418912 (2012). DOI |
19 | Yoon JY, Choi HJ, Jun HS. The effect of phloroglucinol, a component of Ecklonia cava extract, on hepatic glucose production. Mar. Drugs 15: 106 (2017) DOI |
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