• Title/Summary/Keyword: 퇴행성 관절염

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Clinical Results of the Radial Tear of Posterior Root of Medial Meniscus (내측 반월상 연골 후각부 방사형 파열의 임상적 결과)

  • Nha, Kyung-Wook;Jo, Jin-Ho;Lee, Dong-Bong
    • Journal of the Korean Arthroscopy Society
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    • v.11 no.2
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    • pp.128-133
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    • 2007
  • Purpose: To examine the clinical results after arthroscopic meniscectomy of radial tear of medial meniscus. Materials and Methods: We studied 45 cases with the radial tear of medial meniscus which follow up more than 2 years(range 2 to 7 years). Arthroscopic surgery was performed to the patients with grade 0-2 according to the Kellgren and Lawrence classification. Evaluation of cartilage damage was performed on surgical photos according to Outerbridge classification. Evaluation of clinical result was used the modified Lysholm score. Results: The mean pre-operation Lysholm score was 79.1, 71.2, 68.5, 67.9, 67.2, 61.5 and post-operation Lysholm score was 86.3, 75.1, 73.0, 73.1, 73.2, 66.2 and 61.5%, 62.5%, 60.0%, 50.0%, 50.0%, 25.0% improved knee pain and 69.2%, 75.5%, 70.0%, 66.6%, 75.0%, 75.0% were satisfied knee surgery and 30.7%, 20.5%, 20.0%, 50.0%, 25.0%, 50.0% required further surgery in patients respectively. According to Kellgren and Lawrence classification, 7 cases(15.5%) progress grade 3 osteoarthritis. Conclusions: The radial tear of medial meniscus showed the poor results with arthroscopic meniscectomy even if the grade 0-2 osteoarthritis. For the improvement of the clinical results, consider the technique to restore the hoop stresses or use the high tibia osteotomy for preventing the osteoarthritis.

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Arthroscopic Treatment of Osteoarthritis of the Knee(Comparison of the groups with and without mechanical symptom) (슬관절 퇴행성 관절염의 관절경적 치료 - 기졔적 증상이 있는 군과 없는 군과의 비교 -)

  • Kim Cheol-Ho;Lim Chang-Kyun;Cho Seong-Woo;Kim Gi-Hyung;Moon Jin-Woong
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.2 no.2
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    • pp.149-152
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    • 2003
  • Purpose: The purpose of this study is to evaluate the clinical results for the treatment of osteoarthritis of the knee by arthroscopic procedure according to presence or absence of mechanical symptoms. Materials and Methods: We studied sixty patients (60 knees) who underwent arthroscopic procedure for the treatment of osteoarthritis of the knee from October,2000 to January,2002. The average follow up period was 15 months(12-30 months). We evaluated the mechanical symptoms by simple radiographs, history taking and physical examination. We analysed the clinical results by Baumgaertner's scale. Results: The Baumgaetner's score improved from 3.1 preoperatively to 8.1 postoperatively in the group with mechanical symptoms, whereas the scores in the group without mechanical symptom improved from 3.5 preoperatively to 5.4 postoperatively. The patients with mechanical symptoms were satisfied more than the patients without mechanical symptoms. Conclusion: The arthroscopic surgery could be one of good alternative treatment methods for the osteoarthritis of the knee with mechanical symptoms . But, more than these patients will be needed for further evaluation.

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Proteinases and their Inhibitors in Cartilage and Synovial Fluid Acquired from a Canine Osteoarthritic Model (개 퇴행성 관절염 모델을 이용한 연골과 활액 내 단백질 분해 효소와 억제제의 작용 연구)

  • Seo, Jae-Won;Lee, Hae-Beom;Kim, Nam-Soo;Lee, Young-Hoon;Kang, Hyung-Sub;Kim, In-Shik;Park, Sang-Youel
    • Journal of Veterinary Clinics
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    • v.26 no.2
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    • pp.144-149
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    • 2009
  • Chondrocytes and synovial fluid derived markers are used to monitor for osteoarthritis(OA). Specific inhibitors, known as tissue inhibitors of metalloproteinases(TIMP), regulate the proteolytic activity of matrix metalloproteinases(MMP). This study investigated whether MMP and TIMP levels were altered in synovial fluid and cartilage following the experimental induction of OA in canines. Twenty mature beagle dogs underwent a unilateral surgical transection of the cranial cruciate ligament and the medial collateral ligament as well as a medial meniscectomy. Matrix metalloproteinase-2 and MMP-9 levels were assayed using Western blot and TIMP-2 levels were measured with enzyme-linked immunosorbent assays four weeks after OA induction. Increased MMP-2 expression was observed in chondrocytes isolated from cartilage following OA induction, but MMP-9 expression decreased. Matrix metalloproteinase-2 and MMP-9 levels in synovial fluid from the OA induced joint significantly increased compared to those of the sham group. Tissue inhibitors of metalloproteinase-2 concentrations were higher in chondrocytes from the OA cartilage, yet TIMP-2 remained lower in the synovial fluid of OA. This suggests the elevated release of MMP-9 over MMP-2 into the synovial fluid following the cartilage degradation-related death of chondrocytes after OA. Osteoarthritis can be further deteriorated by increased MMP activity in the synovial fluid because TIMP-2 exist low concentration into the extracellular matrix. As a result, MMP activity, particularly MMP-9 activity, can be useful as a biomarker in diagnosing and monitoring the early stages of canine OA.

Effects of Laughter Therapy on Joint Pain, Functional Status of Knee Joint and Depression in Elderly with Degenerative Knee Arthritis (웃음요법이 퇴행성 슬관절염 노인의 관절통증, 관절기능상태, 우울에 미치는 효과)

  • Lee, Yim Sun;Park, Hyo Jung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.9
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    • pp.440-449
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    • 2020
  • This study examined the effects of laughter therapy in the elderly with degenerative arthritis who had joint pain, joint dysfunction, and depression. Through a single-blind, randomized assignment, an experimental group of 26 subjects and a control group of 26 subjects were recruited among the elderly with degenerative knee arthritis, who were over 65 years of age. From January 8 to March 11 of 2019, a total of 16 laughter therapies were administered two times a week, 60 minutes per session, in eight weeks. The pain threshold (p=.012) and joint function status (p<.001), which represents the pain, joint stiffness, and physical function, and depression (p<.001), in the experimental group improved after the eight weeks laughter therapy compared to the control group. Laughter therapy is a therapeutic intervention that can be delivered through physical or intellectual activities. This therapy is a non-invasive procedure and has the advantage that nurses can practice easily with a little training. It can be used as an intervention within community and clinical settings to relieve pain and improve depression in the elderly with arthritis.