• Journal of Life Science
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• v.27 no.1
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• pp.38-43
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• 2017

Glycosyl aesculin, a potent anti-inflammatory agent, was synthesized by transglycosylation reaction, catalyzed by Thermotoga neapolitana ${\beta}-glucosidase$, with aesculin as an acceptor. The key reaction parameters were optimized using response-surface methodology (RSM) and $2{\mu}g$ of the enzyme. As shown by a statistical analysis, a second-order polynomial model fitted well to the data (p<0.05). The response surface curve for the interaction between aesculin and other parameters revealed that the aesculin concentration and reaction time were the primary factors that affected the yield of glycosyl aesculin. Among the tested factors, the optimum values for glycosyl aesculin production were as follows: aesculin concentration of 9.5 g/l, temperature of $84^{\circ}C$, reaction time of 81 min, and pH of 8.2. Under these conditions, 61.7% of glycosyl aesculin was obtained, with a predicted yield of 5.86 g/l. The maximum amount of glycosyl aesculin was 6.02 g/l. Good agreement between the predicted and experimental results confirmed the validity of the RSM. The optimization of reaction conditions by RSM resulted in a 1.6-fold increase in the production of glycosyl aesculin as compared to the yield before optimization. These results indicate that RSM can be effectively used for process optimization in the synthesis of a variety of biologically active glycosides using bacterial glycosidases.

• Proceedings of the Korean Information Science Society Conference
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• 2005.07b
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• pp.433-435
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• 2005

임베디드 시스템은 다수의 디바이스를 컨트롤하여 시스템의 목적을 수행한다. 최근 임베디드 시스템의 요구사항이 증가함에 따라 하나의 임베디드 소프트웨어가 컨트롤하는 디바이스의 종류가 다양해지고 수도 증가하는 추세이다. 다수의 디바이스를 가지고 있는 임베디드 시스템에서 시스템의 신뢰도는 각 디바이스의 신뢰도에 많은 영향을 받는다. 본 논문은 임베디드 시스템의 신뢰도를 측정하기 위해서 통계적 신뢰도 측정 방법 중 한 가지인 마르코프 체인을 이용한 방법을 제안한다. 마르코프 체인은 여러 분야에서 복잡한 시스템을 단순화하여 모델링하고 과거의 변화를 토대로 미래를 예측할 수 있는 방법을 제공한다. 또한 전체 시스템의 확률을 행렬로 계측할 수 있는 방법을 가지고 있어 특정 부분의 확률이 전체 시스템의 확률에 미치는 영향을 산술적으로 계산할 수 있는 장점을 가지고 있다. 본 논문에서 제안하는 임베디드 소프트웨어 마르코프 체인은 테스트 대상 소스를 분석하여 디바이스를 컨트롤하는 루틴과 에러를 핸들링하는 루틴, 일반적인 루틴으로 나누어 각각을 상태로 정의한다. 정의한 각 상태간의 전이는 통계적으로 측정한 디바이스 신뢰도를 확률로 표현한다. 마르코프 체인을 이용하여 임베디드 시스템의 신뢰도를 측정하기 위한 시스템은 소스 분석기와 신뢰도 측정기로 나누어 설계한다. 소스 분석기는 테스트 대상이 되는 소스와 디바이스 드라이버 라이블러리 테이블을 입력으로 하고 소프트웨어의 마르코프 체인을 출력으로 한다 마르코프 체인은 행렬로 표현하고 연산하여 시스템의 신뢰도를 측정한다. 제안하는 시스템의 신뢰도 측정 방법은 부분이 가지고 있는 신뢰도가 전체 신뢰도에 미치는 영향을 산술적으로 측정할 수 있어 시스템이 요구하는 신뢰도에 접근할 수 있는 방법과 근거를 제공하는 장점이 있다.소시키는 장점을 갖는다.것으로 조사되었으며 40대 이상의 연령층은 점심비용으로 더 많은 지출을 하고 있는 것으로 나타났다. 4) 끼니별 한식에 대한 선호도는 아침식사의 경우가 가장 높았으며, 이는 40대와 50대에서 높게 나타났다. 점심 식사로 가장 선호되는 음식은 중식, 일식이었으며 저녁 식사에서 가장 선호되는 메뉴는 전 연령층에서 일식, 분식류 이었으며, 한식에 대한 선택 정도는 전 연령층에서 매우 낮게 나타났다. 5) 각 연령층에서 선호하는 한식에 대한 조사에서는 된장찌개가 전 연령층에서 가장 높은 선호도를 나타내었고, 김치는 40대 이상의 선호도가 30대보다 높게 나타났으며, 흥미롭게도 30세 이하의 선호도는 30대보다 높게 나타났다. 그 외에도 떡과 죽에 대한 선호도는 전 연령층에서 낮게 조사되었다. 장아찌류의 선호도는 전 연령대에서 낮았으며 특히 30세 이하에서 매우 낮게 조사되었다. 한식의 맛에 대한 만족도 조사에서는 연령이 올라갈수록 한식의 맛에 대한 만족도는 낮아지고 있었으나, 한식의 맛에 대한 만족도가 높을수록 양과 가격에 대한 만족도는 높은 경향을 나타내었다. 전반적으로 한식에 대한 선호도는 식사 때와 식사 목적에 따라 연령대 별로 다르게 나타나고 있으나, 선호도는 성별이나 세대에 관계없이 폭 넓은 선호도를 반영하고 있으며, 이는 대학생들을 대상으로 하는 연구 등에서도 나타난바 같다. 주 5일 근무제의 확산과 초 중 고생들의 토요일 휴무와 더불어 여행과 엔터테인먼트산업은 더욱 더 발전을 거듭하고 있으며, 외식은 여행과 여가 활동의 필수적인 요소로써 그 역할을 일조하고 있다. 이와 같은 여가시간의 증가는 독신자들에게는 좀더 많은 여유시간을 가족을 이루고 있는 가족구성원들에게는 가족과의 유대를 강화하는 휴식과 오락의 소비 트렌드를 창출시켰

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.12
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• pp.425-436
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• 2019

This study constructs independent potential variables that are variables expected to affect child abuse reporting intention of child care teachers. In addition, this study establishes a research model based on the relationships between potential variables according to the results of previous studies and planning behavior theory. The purpose of this study was to examine what factors affect and how reporting intention is determined. The subjects of this study included a convenience sample of nursery teachers working in 67 daycare centers in the C region. The following results were obtained. First, the research model proposed in this study was found to be a suitable model to explain the child abuse teacher's intention to report child abuse through the analysis of the measurement and structural models. Second, the child abuse teacher's knowledge of child abuse is an important factor explaining the reporting intention and has an indirect effect through the mediation. Third, attitudes toward reporting of child care teachers were found to be the most direct factor that predicts reporting intentions. Fourth, subjective norms and reporting intentions of child care teachers were not statistically significant. Bsead on these results, basic data for improving child abuse reporting rate of childcare teachers were presented.

• Korean Journal of Ecology and Environment
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• v.46 no.1
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• pp.53-59
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• 2013

The purpose of this study was to analyze the topographic effect of the LAI (Leaf Area Index), which has been widely used as an index that quantifies the structure of forest vegetation in Deogyusan National Park. With this aim, the study was conducted through a regression analysis which took as explanation the following variables: the elevation, slope, aspect, and soil moisture conditions. The LAI was taken as the response variable. Overall, the correlation between the Field-LAI and topographic factors was less than 0.5, which was relatively low. Except for topographic altitude, there was no statistical significance regarding the correlation with other factors. Meanwhile, regarding the orientation of the correlation, the higher the attitude, the steeper slope, the lower the soil moist, the lower the LAI value. The topographic altitude was found as a statistically significant explanation variable. The TWI (Topographic Wetness Index), which was used in this study to explain the soil moisture conditions, was not significantly related to the LAI distribution. The results of this study are expected to be utilized as basic data in more accurate forecasting the LAI distribution using remote sensing data.

• Korean Journal of Food Science and Technology
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• v.31 no.2
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• pp.385-390
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• 1999

Noodle was made using a combination of yulmu, wheat and water through mixture design. Statistical models of yulmu noodle were shown by analysing tensile stress and color $(L^{*})$, and sensory evaluation with other constraints. Analysing the linear and non-linear model, the linearity in the values of tensile stress, lightness $(L^{*})$ and sensory evaluation showed that each component worked separately without interactions. In studying the component effect on the response by trace plot, the result indicated that the increase in the amount of yulmu enhanced tensile stress of noodle while degrading $L^{*}$ value and sensory evaluation score. In the range of satisfying the conditions of noodle in every tensile stress, $L^{*}$ value and sensory evaluation point, the optimum mixture ratio of yulmu : wheat : water was 2.27% : 66.28% : 28.45% based on least cost linear programming. In this calculation, the least cost was 9.924 and estimated potential results of the response for tensile stress was 2.234 N and those for $L^{*}$ was 82.39. Finally, the potential response results affected by mixture ratio of yulmu, wheat and water were screened using Excel.

• The Journal of Bigdata
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• v.1 no.1
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• pp.67-75
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• 2016

The study analyzed big data extracted from Google and social media to identify factors related to searches on cyber bullying in Korea and America. Korea's cyber bullying analysis was conducted social big data collected from online news sites, blogs, $caf{\acute{e}}s$, social network services and message for between January 1, 2011 and March 31, 2013. Google search trends for the search words of stress, exercise, drinking, and cyber bullying were obtained for January 1, 2004 and December 22, 2013. The main results of this study were as follows: first, the significant factors stress were cyber bullying that Korea more than America. Secondly, a positive relationship was found between stress and drinking, exercise and cyber bullying both Korea and America. Thirdly, significant differences were found all path both Korea and America. The study shows that both adults and teenagers are influenced in Korea. We need to develop online application that if cyber bullying behavior was predicted can intervene in real time because these actual cyber bullying-related exposure to psychological and behavioral characteristic.

• Journal of the Korean Geotechnical Society
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• v.34 no.5
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• pp.19-35
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• 2018

The necessity of predicting the spatial information of the site-specific seismic response, which is essential information for the comprehensive earthquake disaster countermeasures, is increasing for the mid-west urban areas where the earthquake-induced damages can be increased due to frequent occurrence of mid-scale earthquake such as 2016 Gyeongju Earthquake and 2017 Pohang Earthquake. Especially, researches on strategic securing of site survey datasets and understanding the site-specific site response characteristics were conducted for Gyeonggi-do, South Korea. In this study, a GIS-based framework for site-specific assessment of site response and induced vulnerable area in Gyeonggi-do, South Korea was proposed. Geo-Data based on GIS platform was constructed for regional estimation of geotechnical characteristics by collecting borehole and land coverage datasets. And the geo-spatial grid information was developed for deriving spatial distribution of geotechnical layer and site response parameters based on the optimization of the geostatistical interpolation method. Accordingly, base information for Improving earthquake preparedness measures was derived as seismic zonation map with administrative sub-units considering the quantitative site effect of Gyeonggi-do.

• Journal of Korea Society of Industrial Information Systems
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• v.24 no.5
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• pp.115-120
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• 2019

In this paper, we present the results of the performance statistical analysis of the multi-robot formation control based on receding horizon particle swarm optimization (RHPSO). The formation control problem of multi-robot system can be defined as a constrained nonlinear optimization problem when considering collision avoidance between robots. In general, the constrained nonlinear optimization problem has a problem that it takes a long time to find the optimal solution. The RHPSO algorithm was proposed to quickly find a suboptimal solution to the optimization problem of multi-robot formation control. The computational complexity of the RHPSO increases as the number of candidate solutions and generations increases. Therefore, it is important to find a suboptimal solution that can be used for real-time control with minimal candidate solutions and generations. In this paper, we compared the formation error according to the number of candidate solutions and the number of generations. Through numerical simulations under various conditions, the results are analyzed statistically and the minimum number of candidate solutions and the minimum number of generations of the RHPSO algorithm are derived within the allowable control error.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.3
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• pp.255-264
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• 2022

The active ingredients of Napttegi Kong(GML, Glycine max landrace), a type of native rare soybeans, were identified, and an ultrasonic extraction method was introduced as an eco-friendly extraction method. Through the component analysis of the Napttegi Kong extract, the epicatechin, which was not found in conventional soybeans, was identified. For effective extraction using ultrasonic, the main extraction conditions were optimized using the response surface analysis method. Through the Box-Behnken design process, 15 experiments were conducted with the extraction temperature, the ratio of extraction solvent/solution, and extraction time as key independent variables. A quadratic regression equation for the two dependent variables, epicatechin content and total isoflavone content, was derived, and the coefficients of determination were found to be high as R² = 0.9939 and R² = 0.9844, respectively, confirming that the correlation showed high significance. The extraction conditions satisfying the maximum expectations of these two dependent variables were predicted. to be 40.4℃ of extraction temperature, 19.3 times of extraction solvent/solution, and 91 sec of extraction time. The expected value and the actual experimental value of the epikatechin content and the total isoflavone content were similar, so it was confirmed that this experimental method is a highly reliable optimization model.

• Korean Journal of Agricultural and Forest Meteorology
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• v.24 no.4
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• pp.337-345
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• 2022

For data such as rainfall and soil moisture, it is important to obtain the values of all points required as geostatistical data. Spatial interpolation is generally performed in this process, and commercial software such as ArcGIS is often used. However, commercial software has fatal drawbacks due to its high expertise and cost. In this study, R, an open source-based environment with ArcGIS, a commercial software, was used to compare the differences according to the processing environment when performing spatial interpolation. The data for spatial interpolation was weather forecast data calculated through Land-Atmosphere Modeling Package (LAMP)-WRF model, and soil moisture data calculated for each cumulative rainfall scenario. There was no difference in the output value in the two environments, but there was a difference in user interface and calculation time. The results of spatial interpolation work in the test bed showed that the average time required for R was 5 hours and 1 minute, and for ArcGIS, the average time required was 4 hours and 40 minutes, respectively, showing a difference of 7.5%. The results of this study are meaningful in that researchers can derive the same results in a commercial software environment and an open source-based environment, and can choose according to the researcher's environment and level.