• Title/Summary/Keyword: 탐색적 연구

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Antimicrobial Activity of Extracts from Some Traditional Oriental Medicinal Plants against Dental Caries Bacteria (치아우식 원인균에 대한 한약재 추출물의 항균효과)

  • Lee, Hee-Woen;Lee, Pureunhaneul;Kwon, Hyun-Jung;Han, Kook-Il;Han, Man-Deuk
    • Journal of dental hygiene science
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    • v.13 no.1
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    • pp.45-52
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    • 2013
  • Antimicrobial activity of extract from some traditional oriental medicinal plants were evaluated for their antimicrobial activity against six oral pathogens, Streptococcus salivarius, Streptococcus oralis, Streptococcus mutans, Streptococcus sanguinis, Lactobacillus acidophilus and Lactobacillus casei, which are associated with caries disease. The antimicrobial activity was examined by determining the inhibition zone using the disc diffusion assay. In antibacterial activity test, extracts of Scutellaria baicalensis, Chrysanthemum indicum, Kochia scoparia, Hydnocarpus anthelmintica and Caesalpinia sappan showed inhibitory effects (40 mg/ml) against tested caries bacteria. Especially, the C. sappan extract showed the strongest activity on S. oralis (40 mm), L. casei (35 mm) and S. mutans (28 mm). Thus, this result suggests that C. sappan may be applicable to preventing dental caries.

Recycling Agricultural Wastes as Feed for Mealworm (Tenebrio molitor) (갈색거저리 대량사육을 위한 농업부산물 대체먹이 탐색)

  • Kim, Sun Young;Chung, Tae-Ho;Kim, Seong-Hyun;Song, Sungho;Kim, Namjung
    • Korean journal of applied entomology
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    • v.53 no.4
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    • pp.367-373
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    • 2014
  • In order to investigate the impact of recycling agricultural wastes as feed for mealworm (Tenebrio molitor), we evaluated the replacing effect by the different level of tangerine shell, Chinese cabbage, king oyster mushroom (Pleurotus eryngii) and Enoki mushroom (Flammulina velutipes) substrates on wheat bran feed. Larval survival rate, larval weight, developmental period of larva, pupation rate and pupal weight were evaluated. In tangerine shell and Chinese cabbage replacement group, no replacing effects found. In all groups replacing by spent King oyster mushroom (Pleurotus eryngii) substrate, survival rate of larva was similar to that of control group but larvae weighed less than control group significantly. Developmental period of larva increases in the group of King oyster mushroom substrate replacement. Larval and pupal weight in Enoki mushroom (Flammulina velutipes) substrate by the level of 40 and 50%, replacement effect showed best results in successive breeding considering pupation rate. It is concluded that replacing 40 and 50% of Enoki mushroom (Flammulina velutipes) substrate is appropriate to substituted diet of Tenebrio molitor larvae.

Isolation and HPLC-DAD validation of xanthoangelol in Lespedeza bicolor extract (싸리나무 추출물의 Xanthoangelol 분리 및 HPLC-DAD 밸리데이션)

  • Woo, Hyun Sim;Kim, Yeong-Su;Oh, Yu Jin;Cho, Hae Jin;Song, Se-Kyu;Kim, Dae Wook
    • Korean Journal of Food Science and Technology
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    • v.52 no.1
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    • pp.26-30
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    • 2020
  • This study was undertaken to determine the characteristics of xanthoangelol, the major chalcone constituent derived from the extracts of different parts of Lespedeza bicolor. Xanthoangelol was isolated from the root extract using column chromatography and used as a standard for quantitative analysis. The structure of the isolated compound was established based on spectroscopic evidence. The HPLC-DAD method was validated for specificity, linearity, precision, accuracy, limit of detection, and limit of quantitation. The calibration curve of xanthoangelol had significant linearity (R2>0.9999). Limit of detection and limit of quantitation 0.018 and 0.059 ㎍/mL, respectively. The relative standard deviation values of precision test, and intra- and inter-day tests were less than 0.22 and 0.40%, respectively. In the recovery test, the accuracy ranged from 98.98-102.78% with RSD values less than 0.13%. The method validation parameters indicate the applicability of the HPLC method for quality control of food or drug formulations containing L. bicolor.

Various physiological effects from fruiting body extracts of Phellinus baumii (장수진흙버섯 자실체 추출물의 다양한 생리활성 효과)

  • Yoon, Ki Nam;Lee, Tae Soo
    • Journal of Mushroom
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    • v.18 no.3
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    • pp.260-267
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    • 2020
  • Phellinus baumii, a white-rot fungus, has been used for centuries as folk medicine in China, Japan, and Korea. This study aimed to evaluate the in vitro anti-diabetic, and anti-cholinesterase, and in vivo anti-inflammatory effects of the fruiting bodies of P. baumii. The methanol (ME) and hot water (HE) extracts (2.0 mg/mL) of P. baumii fruiting bodies suppressed α-amylase activity, exactly 61.33%, and 65.00%, respectively; of note, acarbose, the positive control, inhibited 93.33% of the α-amylase activity. Moreover, the ME and HE (2.0 mg/mL) inhibited 89.67% and 91.00%, respectively, of the activity of α-glucosidase activity, whereas the same concentration of acarbose suppressed 84.67% of the α-glucosidase activity. The ME and HE (1.0 mg/mL) also inhibited 96.05% and 94.58%, respectively, of the acetylcholinesterase (AChE) activity; galanthamine, the positive control, led to an inhibition of 81.12%. The butyrylcholinesterase (BChE) activity was also inhibited by ME and HE (1.0 mg/mL; 91.05% and 82.27%, respectively); of note, the same concentration of galanthamine suppressed 81.12% of the BChE activity. The production of NO in LPS-induced RAW 264.7 macrophages was significantly suppressed by both ME and HE treatments. Importantly, the carrageenan-activated rat hind-paw edema was significantly reduced 2-6 h after ME administration (50 mg/mL). Taken together, the results suggest that the fruiting bodies of P. baumii have α-amylase, α-glucosidase, α-cholinesterase, and anti-inflammatory activities, and, therefore, may be good natural sources for the promotion of human health.

The Efficient Method of Parallel Genetic Algorithm using MapReduce of Big Data (빅 데이터의 MapReduce를 이용한 효율적인 병렬 유전자 알고리즘 기법)

  • Hong, Sung-Sam;Han, Myung-Mook
    • Journal of the Korean Institute of Intelligent Systems
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    • v.23 no.5
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    • pp.385-391
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    • 2013
  • Big Data is data of big size which is not processed, collected, stored, searched, analyzed by the existing database management system. The parallel genetic algorithm using the Hadoop for BigData technology is easily realized by implementing GA(Genetic Algorithm) using MapReduce in the Hadoop Distribution System. The previous study that the genetic algorithm using MapReduce is proposed suitable transforming for the GA by MapReduce. However, they did not show good performance because of frequently occurring data input and output. In this paper, we proposed the MRPGA(MapReduce Parallel Genetic Algorithm) using improvement Map and Reduce process and the parallel processing characteristic of MapReduce. The optimal solution can be found by using the topology, migration of parallel genetic algorithm and local search algorithm. The convergence speed of the proposal method is 1.5 times faster than that of the existing MapReduce SGA, and is the optimal solution can be found quickly by the number of sub-generation iteration. In addition, the MRPGA is able to improve the processing and analysis performance of Big Data technology.

Identification of Uncertainty in Fitting Rating Curve with Bayesian Regression (베이지안 회귀분석을 이용한 수위-유량 관계곡선의 불확실성 분석)

  • Kim, Sang-Ug;Lee, Kil-Seong
    • Journal of Korea Water Resources Association
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    • v.41 no.9
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    • pp.943-958
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    • 2008
  • This study employs Bayesian regression analysis for fitting discharge rating curves. The parameter estimates using the Bayesian regression analysis were compared to ordinary least square method using the t-distribution. In these comparisons, the mean values from the t-distribution and the Bayesian regression are not significantly different. However, the difference between upper and lower limits are remarkably reduced with the Bayesian regression. Therefore, from the point of view of uncertainty analysis, the Bayesian regression is more attractive than the conventional method based on a t-distribution because the data size at the site of interest is typically insufficient to estimate the parameters in rating curve. The merits and demerits of the two types of estimation methods are analyzed through the statistical simulation considering heteroscedasticity. The validation of the Bayesian regression is also performed using real stage-discharge data which were observed at 5 gauges on the Anyangcheon basin. Because the true parameters at 5 gauges are unknown, the quantitative accuracy of the Bayesian regression can not be assessed. However, it can be suggested that the uncertainty in rating curves at 5 gauges be reduced by Bayesian regression.

Lateral Root Formation and Growth of Soybean Sporouts Treated with Various Solutions (다양한 물질처리에 의한 콩나물의 세근형성 및 생장)

  • Kang, Jin-Ho;Park, Cheol-Jong;Yoon, Soo-Young;Jeon, Seung-Ho;Hong, Dong-Oh
    • Korean Journal of Medicinal Crop Science
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    • v.13 no.1
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    • pp.6-10
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    • 2005
  • Lateral roots of soybean sprouts should deeply affect their quality and marketability. The study was done to compare the effects of ocher, chitosan, corn kennel, tea (Thea sinensis L.) and hard rubber tree (Eucommia ulmoides Oliver) leaf extracts on lateral root formation, growth and morphological characters of the sprouts. Seeds of three cultivars, Pungsannamulkong, Sowonkong and Junjery, were imbibed for 5 hours into their 10% solutions and cultured for 6 days. The cultured sprouts were classified into 4 categories to calculate their composition rates on the base of hypocotyl lengths;>7 cm (A), 4 to 7 cm (B), < 4 cm (C) and not germinated (D), and their morphological characters, fresh and dry weights were measured. Composition rate of A was the lowest in Junjery of the three cultivars, while that of C showed reverse result compared to A. This results was the most distinct in hard rubber tree leaf extracts (HRTLE) of the five treatments. In HRTLE treatment, lateral root formation rate were formed in almost of Sowonkong although reduced in order of Pungsannamulkong and Junjery. However, there was no significant difference between the other treatments. Lateral roots per sprout were the lowest in HRTLE treatment of the 5 treatments. In all treatments except the chitosan treatment, the roots were most formed in Sowonkong but least in Junjery. Sprout length adding hypocotyl and root was the shortest in Junjery compared to the other two cultivars. and was the longest in tea leaf extract treatment but the shortest in HRTLE treatment. The result in total fresh weight of sprouts was similar to that of the sprout length.

Biological Activities in roots of Glycyrrhiza uralensis Fisch (감초 세근의 생리활성 탐색)

  • Chung, Woo-Teak;Lee, Seo-Ho;Cha, Moon-Suk;Sung, Nak-Sul;Hwang, Baek;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.9 no.1
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    • pp.45-54
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    • 2001
  • The biological activities of ethanol, ethanol: water(1 : 1v/v) and water extracts from Glycyrrhiza uralensis Fisch, glycyrrhizin and enzymatically hydrolyzed glycyrrhizin were compared. About 50% of the growth of MCF7, A549, Hep3B and AGS cells were inhibited in adding 1.0 g/L of the crude extracts, glycyrrhizin and enzymatically hydrolyzed glycyrrhizin. For example, the ethanol extract inhibited 76%, 66% in MCF7 and Hep3B cells by adding 1.0 g/L. For cytotoxicity on human normal liver cell(WRL-68), the crude extracts were scored as above 26%. For the result of antimutagenecity using CHO V79 cell, the crude extracts proved more effective than other samples. The growth of human immune B and T cells were enhanced up to $1.2{\sim}1.3$ times by adding the crude extracts. In inhibitory effect of ${\alpha}-glucosidase$ activity was showed that the ethanol extract, water extract and ethanol: water (1 : 1v/v) extract were appeared 65%, 68%, 62% in adding 1.0 g/L. The higher enhancement of glutathione -S-transferase activity was observed in the ethanol extract as 257% compared to the control in adding 1.0 g/L. From the results, the biological activities of the crude extracts were equivalent or higher than glycyrrhizin and enzymatically hydrolyzed glycyrrhizin.

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Design and Implementation of DNS Name Autoconfiguration for Internet of Things Devices (사물인터넷 디바이스를 위한 DNS 네임 자동설정의 설계 및 구현)

  • Lee, Sejun;Jeong, Jaehoon
    • Journal of KIISE
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    • v.42 no.11
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    • pp.1441-1451
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    • 2015
  • As one of the most spotlighted research areas, these days, the Internet of Things (IoT) aims to provide users with various services through many devices. Since there exist so many devices in IoT environments, it is inefficient to manually configure the domain name system (DNS) names of such devices. Thus, for IPv6-based IoT environments, this paper proposes a scheme called the DNS Name Autoconfiguration (DNSNA) that autoconfigures an IoT device's DNS name and manages it. In the procedure for generating and registering an IoT device's DNS name, the standard protocols of the Internet Engineering Task Force (IETF) are used. Since the proposed scheme resolves an IoT device's DNS name into an IPv6 address in unicast through a DNS server, it generates less traffic than multicast-based mDNS (Multicast DNS) which is a legacy DNS application for the DNS name service in the smart home. Thus, the proposed scheme is more appropriate in multi-hop IoT networks than mDNS. This paper explains the design of the proposed scheme and its service scenarios, such as smart home and smart road. It also explains the implementation and testing of the proposed scheme in the smart grid.

The Study on the Education and Training for the Personnel in the Military Acquisition Field in US (미국 국방획득인력의 교육·훈련체계 및 관련동향)

  • Kim, Myunghyun;Lee, Youngwoo;Kim, Kyoungrok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.3
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    • pp.223-229
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    • 2020
  • The current technological advances are changing the way people live. In the history of war in the past, nations or people with an edge in military science and technology have always been the victor. The emergence of new technologies not only alters war patterns drastically but also affects military operational concepts and organizational systems. As the paradigm of the security environment changes, developed countries are investing heavily in defense R & D for their security. Therefore, the importance of professionalism of the defense acquisition personnel who perform their tasks from the exploration and development of weapon systems to mass production, deployment, and logistics support cannot be overemphasized. In the United States, an advanced country in this field, to improve the work efficiency of acquisition personnel in the defense field, the Directive of Ministry of Defense issued a law on education and training career development for personnel in 1990. The present study refers to related materials, such as the Desk Guide for the main education requirements for the US acquisition personnel in the military field, which contributes to the improvement of the workforce of the acquired manpower after the systematic education system.