• Title/Summary/Keyword: 크기와 비례

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The Prognostic Significance of the Number of Resected Lymph Nodes in Gastric Cancer Patients (근치 절제술을 시행한 위암에서 절제림프절 수의 임상적 의의)

  • Kim, Se-Jin;Jang, You-Jin;Kim, Jong-Han;Park, Sung-Soo;Park, Seong-Heum;Kim, Seung-Ju;Mok, Young-Jae;Kim, Chong-Suk;Ahn, Hyong-Gin
    • Journal of Gastric Cancer
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    • v.9 no.4
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    • pp.246-255
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    • 2009
  • Purpose: The objectives of this study were to investigate the impact of the number of resected lymph nodes on the survival of gastric cancer patients who underwent curative resection, and to evaluate the cut-off values that can have an influence on survival on the tumor stage-stratified analysis. Materials and Methods: The subjects were 949 gastric cancer patients who underwent curative resection at Korea University Medical Center from 1992 to 2002. They were classified according to the depth of tumor invasion, and the influence of the number of resected lymph nodes on survival was investigated. The cut-off value for the number of resected lymph nodes was determined as the smallest value that showed a significant survival difference. Results: The tumor size, location, lymph node stage, the number of metastatic lymph nodes and the number of resected lymph nodes were significantly different according to the tumor stage. The average number of resected lymph nodes was about 39, and it showed linear correlation with the number of metastatic lymph nodes. On the Cox proportional hazard model, the cut-off values of the number of resected lymph nodes, as corrected by the number of metastatic lymph nodes, was 14 for all the patients, 15 for the pT1 patients, 28 for the pT2 patients and 37 for the pT3 patients, respectively. Conclusion: Retrieving a number of lymph nodes that is more than the cut-off value could improve the survival of gastric cancer patients. Surgeons should also make efforts to perform an exact and thorough D2 lymph node dissection. Therefore, we urge surgeons to perform D2 dissection and pathologists should examine an certain exact number of lymph nodes.

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Morpho-anatomical Characteristics of Different Panicles in Low and High Tillering Rices (벼 소얼성과 다얼성 품종에서 분얼별 이삭의 형태 해부학적 특성)

  • Kim, Je-Kyu;B.S. Vergara
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.36 no.6
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    • pp.568-575
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    • 1991
  • The morpho-anatomical characteristics of panicle in rice plant is generally correlated with the number of spikelets and grain weight per panicle. For the increase of grain yield potential in rice, a low -tillering plant type with large panicles has been suggested as an ideotype. This study was conducted to investigate the panicle morphology and peduncle anatomy of different tillers within a plant in low -and high-tillering cultivars and their relationships on the number of spikelets and grain weight per panicle. A low-tillering, large panicled IR25588 was compared with a high-tillering. small panicled IR58. IR25588 had more inner(IVB) and outer vascular bundles (OVB). bigger peduncle diameter and peduncle thickness just below the panicle neck node than IR58. The top six tillers(M. P1, P2, P3. P4 and S1P2) within a plant had more IVB and OVB. larger peduncle diameter and thickness than the rest of the tillers in both cultivars. Tillers that emerged earlier had more IVB and OVB than tillers that emerged Jater. The total number of primary and secondary rachis-branches of IR25588 was much higher than that of IR58. IR25588 had more number of spikelets per panicle than IR58. and the top six panicles showed more spikelets per panicle than the rest of the panicles in both cultivars. The peduncle diameter was more important than peduncle thickness on the spikelet differentiation and panicle weight. especially in low-tillering cultivars. The number of IVB and OVB were highly correlated with the number of rachis-branches. spikelets and grain weight per panicle. The number of spikelets per IVB and spikelets per primary branch were higher in IR25588 than IR58 indicating the higher sink strength in low -tillering with large panicled cultivars than in high-tillering with small panicled cultivars. Based on the morpho-anatomical characteristics of a low-tillering cultivar and the top six tillers within a plant. the present results could be support that 'a low-tillering sturdy culms with large panicles' is an ideo-type of rice plant for increasing grain yield potential.potential.

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Effects of Physical Parameters on Water Quality in Agricultural Reservoirs (농업용 저수지의 물리적 인자가 수질에 미치는 영향)

  • Jeon, Ji-Hong;Ham, Jong-Hwa;Kim, Ho-Il;Hwang, Soon-Jin;Yoon, Chun-Gyeong
    • Korean Journal of Ecology and Environment
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    • v.35 no.1 s.97
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    • pp.28-35
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    • 2002
  • The effect of physical parameters on water quality was analyzed using monitoring data of 193 agricultural reservoirs. The retention time of reservoirs ($t_d$) ranged between 10 and 140 days, and the ratio of drainage area (DA) to reservoir surface area (SA) was between 10 and 120. Both ratios of DA/SA and total area (TA)/ reservoir storage (ST) in Korean agricultural reservoirs were relatively greater than those in natural lakes in other countries. As retention time was plotted against DA/SA ratio, it was shorter in Korean reservoirs than natural lakes. The semi-logarithmic relationship between TA/SA and t>$t_d$ was $t_d\;=\;42.21(TA/ST)^{-1}$ (n = 50, $R^2\;=\;0.89$). While areal loading of total phosphorus (TP) was below $4\;gTP{\cdot}m^{-2}{\cdot}yr^{-1}$ in general, it exceeded $10\;gTP{\cdot}m^{-2}{\cdot}yr^{-1}$ in reservoirs where DA/SA ratio was greater than 100, which implies that areal loading of TP increases as DA/SA ratio increases. Chl-a concentration was positively related with the mean depth of reservoir, implying the higher Chl-a concentration with deeper the mean depth. Therefore, the deeper reservoir might be advantageous in water quality management perspective if other morphological conditions are similar. The empirical regression equation using physical parameters was also suggested in the estimation of TP concentration in the reservoirs. Combined information presented in this paper might be applicable to the water quality management in agricultural reservoirs.

Analysis of Prognositic Factors and Long-tenn Survival According to the Pattern of Lymph Node Metastasis in Surgically Resected N2 Non-Small Cell Lung Cancer(NSCLC) (N2 병기의 비소세포성 폐암 수술 후 림프절 전이 양태에 따른 생존율 비교 및 예후 인자 분석)

  • Chung, Kyung-Young;Kim, Si-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.49 no.4
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    • pp.474-485
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    • 2000
  • Background : Current studies on multimodal strategy for N2 non-small cell lung cancer are being high interest, have drawn much attention. N2 lung cancer, however, is composed of is divided into several sub groups with that have different prognoses. The prognostic factors still remain controversial. Methods : Between January 1990 and June 1999, 180 patients with N2 lung cancer who underwent surgical resection were investigated, excluding 10 of these for surgical mortality. All patients underwent mediastinal lymph node dissection. 20 clinicopathologic factors were investigated by univariable and multivariable analyses to identify significant prognostic factors among resected N2 disease. Results : The overall 5-year survival rate was 20.6%. Multivariable analyses among overall patients revealed 3 significant prognostic factors : Age, Histologic type, Vascular invasion. Based on the result, 49 patients with both age more than 60 and pathologic Non-squamous cell showed a 5-year survival of 5.0%, whereas 37 patients with neither of the factors showed a 5-year survival of 56.6%(p<0.001). And 12 patients with both vascular invasion and pathologic Non-squamous cell showed a 5-year survival of 11.9%, whereas 67 patients with neither of the factors showed a 5-year survival of 33.6%(p=0.01). Conclusion : The prognosis of surgically resected N2 disease varies according to the 3 significant prognosis factors. Tumor size may be an additional influencing factor in the prognosis of N2 disease.

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A Study on the Effect of O$_2$ annealing on Structural, Optical, and Electrical Characteristics of Undoped ZnO Thin Films Deposited by Magnetron Sputtering (산소 어닐링이 마그네 트론 스퍼터링으로 증착된 undoped ZnO박막의 구조적, 광학적, 전기적 특성에 미치는 영향에 대한 연구)

  • Yun, Eui-Jung;Park, Hyeong-Sik
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.46 no.7
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    • pp.7-14
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    • 2009
  • In this paper, the effects of annealing conditions on the structural ((002) intensity, FWHM, d-spacing, grain size, (002) peak position), optical (UV peak, UV peak position) and electrical properties (carrier concentrations, resistivity, mobility) of ZnO films were investigated. ZnO films were deposited onto SiO$_2$/si substrates by RF magnetron sputtering from a ZnO target. The substrate was not heated during deposition. ZnO films were annealed in temperature ranges of $500\sim650^{\circ}C$ in the O$_2$ flow for 5$\sim$20 min. The film average thicknesses were in the range of 291 nm. The surface morphologies and structures of the samples were characterize by SEM and XRD, respectively. The optical properties were evaluated by photoluminescence (PL) measurement at room temperature (RT) using a He-Cd 325 nm laser. As the annealing temperature and time vary, the following relations were also observed: (1) proportional relationships among UV intensity (002) intensity, and grain size exist, (2) UV intensity is inversely proportional to FWHM, (3) there is no special relationship between UV intensity and electron carrier concentrations, (4) d-spacing is inversely proportional to (002) peak position, (5) UV peak position in the range of 3.20$\sim$3.24 eV means that ZnO films have a n-type conductivity which was consistent with that obtained from the electrical property, (6) the optimal conditions for the best optical and structural characteristics were found to be oxygen fraction, (O$_2$/(O$_2$+Ar)) of 0.2, RF power of 240W, substrate temperature of RT, annealing condition of 600$^{\circ}C$ for 20 min, and sputtering pressure of 20 mTorr.

Conversion of an Anaerobic Digester to Thermophilic Range (혐기성소화조(嫌氣性消和槽)의 고온(高溫)에로의 전환(轉換))

  • Chang, Duk;Chung, Tai Hak
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.6 no.4
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    • pp.21-28
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    • 1986
  • Conversion of anaerobic mesophilic digestion to thermophilic range has been investigated using a synthetic sludge. When temperature was raised at a rate of 2, 1, and $0.5^{\circ}C$ per day with continuous feeding, a lower reaction rate was observed with a high rate of temperature change. Although methane fermentation ceased completely for an digesters at thermophilic temperature, acid fermentation continued. Methane fermentation was never achieved even with neutralization during 6 months of resting. The methane formers were completely inactivated by the temperature shock and accumulation of volatile acids due to continuous feeding, while the acid formers lost biological activity quickly, but gradually acclimated to a high temperature. When temperature was raised without feeding, successful thermophilic digestion was achieved with 1 day of resting at thermophilic temperature at a rate of $1^{\circ}C$ per day, and also achieved with 20 days of resting at a direct increase. Conversion to a thermophilic range is easily achieved with resting. A short period of resting is required at a low rate of temperature increase, while a long period of resting enough to balance methane formers with acid fermers makes a conversion possile when temperature is raised at a high rate. Soured thermophilic digesters were recovered after seeding of mesophilic sludges, and sludge seeding could be a good method of start-up, conversion, or recovery of a thermophilic digester. Significant amount of thermophiles seemed to be present in the mesophilic digesters.

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Study on Tumor Control Probability and Normal Tissue Complication Probability in 3D Conformal Radiotherapy (방사선 입체조형치료에 대한 종양치유확율과 정상조직손상확율에 관한 연구)

  • 추성실
    • Progress in Medical Physics
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    • v.9 no.4
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    • pp.227-245
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    • 1998
  • A most appropriate model of 3-D conformal radiotherapy has been induced by clinical evaluation and animal study, and therapeutic gains were evaluated by numerical equation of tumor control probability(TCP) and normal tissue complication probability (NTCP). The radiation dose to the tumor and the adjacent normal organs was accurately evaluated and compared using the dose volume histogram(DVH). The TCP and NTCP was derived from the distribution of given dosage and irradiated volume, and these numbers were used as the biological index for the assessment of the treatment effects. Ten patients with liver disease have been evaluated and 3 dogs were sacrificed for this study. Based on the 3-D images of the tumor and adjacent organs, the optimum radiation dose and the projection direction which could maximize the radiation effect while minimizing the effects to the adjacent organs could be decided. 3). The most effective collimation for the normal adjacent organs was made through the beams eye view with the use of multileaf collimator. When the dose was increased from 50Gy to 70Gy, the TCP for the conventional 2-port radiation and the 5-port multidimensional therapy was 0.982 and 0.995 respectively, while the NTCP was 0.725 and 0.142 respectively, suggesting that the 3-D conformal radiotherapy might be the appropriate therapy to apply sufficient radiation dose to the tumor while minimizing the damages to the normal areas of the liver. Positive correlation was observed between the NTCP and the actual complication of the normal liver in the animal study. The present study suggest that the use of 3-D conformal radiotherapy and the application of the mathematical models of TCP and NTCP may provide the improvements in the treatment of hepatoma with enhanced results.

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A Study on Natural Scene Figuration Possibility - Centering around Gyeongnam Area(Namhae Gacheon Village, Sancheong Imchon Village, Hamyang Doma Village) Rice Terraces - (자연경관 조형화 가능성에 관한 연구 - 경남지역(남해가천마을, 산청임촌마을, 함양도마마을) 다랑이논을 중심으로 -)

  • Youn, Kyung-Sook;Lee, Jae-Keun
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.28 no.1
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    • pp.113-119
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    • 2010
  • This study examined figurative characters of rice terraces, and is intended to seek figurative possibility of a natural scene by selecting Gyeongnam Area Namhae Gacheon rice terraces, Sancheong Imcheon rice terraces and Hamyang Macheon rice terraces through an analysis of the target land. As a theoretical background, studies of a natural scene and figuration-related literature were looked into, and for figuring a natural scene on the basis of the results, the character of the topography of rice terraces was divided into 9 items as follows by generalizing the inspiration obtained from the natural scenic character and spatial character of rice terraces represented from the topography: (1) Inclination showing the degree of the slope of rice terraces, (2) The bending showed by unevenness of the edge line of rice terraces, (3) The degree of parallelism of the up-and-down edge line, (4) The size of the width of the section of each rice terrace, (5) The area of the total rice terraces, (6) Step gap that indicates the difference of high and low of the up-and-down small rice terraces, (7) Figuration as an image represented by the external form of the total rice terraces, (8) Naturalness and artificiality kept by the total scene, (9) Softness of cornerstones or soil that forms small rice terraces, an atmosphere produced by the total scenes, etc. The results of analysis made through GIS, with rice terraces of Gyeongnam Namhae, Sancheong and Hamyang Area as the target land, are as follows. First, the steeper the inclination is, the higher the step difference of cornerstones becomes, and the steeper the inclination, the narrower the area and width become, so that it could be known that, in rice terraces, inclination is proportional to step difference and the area is inversely proportional to the width. Second, it is considered that line showed in rice terraces, area elements and reiteration, repeated changes, and changes in the scene affected by the surrounding environment including those according to season can be converted into a variety of images according to an individual disposition. Third, it was decided that it is possible to figure repetitive composition and directivity, motility, order and change, etc. into a common type drawn from each target land. This paper, as a study of basic materials for expressing figuration in an environment field, investigated and analyzed the surrounding environment of the target land, and is significant in that it attempted the possibility of being able to generalize the environmental beauty of the target land as one figurative element. More precise studies are expected to be made later.

Effects of Single and Repeated Electroconvulsive Shock on the Acetylcholine and Polyamine Contents in Temporal Cortex and Decorticated Cerebrum of Mice (경련성 전기충격에 의하여 나타나는 측뇌-피질과 피질을 제외한 대뇌의 Acetylcholine및 Polyamine 함량-변동에 관한 연구)

  • Choi, Sang-Hyun;Lee, Hak-Hee;Park, Chung-San;Chun, Boe-Gwun;Chun, Yeon-Sook
    • The Korean Journal of Pharmacology
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    • v.27 no.1
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    • pp.13-20
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    • 1991
  • There are some rather conflicting reports correlating ECS-induced changes of brain acetylcholine, and recently, Zawia and Bondy(1990) proposed the biological role of polyamine system in the long-term adaptive responses of brain to electrical stimulation. This study was undertaken to evaluate the effects of a single or repeated ECS(10mA, 100cps, 1sec; 5 ECS spread out over 9 days) on the brain acetylcholine(ACh) and polyamine contents of male mice. The ACh contents of temporal cortex(TCx) and decorticated cerebrum(dc-CB) were markedly increased by 79.9% and 49.4%, respectively, 10 and 30 min after ECS, and the increases were significantly attenuated with repeated 5 ECS, particularly in dc-CB. The putrescine concentrations of both TCx and dc-CB were little different and not affected by 1 ECS or 5 ECS. But the spermidine(Sd) concentration was higher in dc-CB and spermine(Sm) higher in TCx. While they were moderately decreased after 1 ECS, and their decreases were accentuated after 5 ECS, particularly in dc-CB.Sm(30mg/kg, i.p. inject. 30min before ECS) did not affect the ECS-induced increase of ACh content. Thease results suggest that both of brain ACh and polyamine may be implicated with the long-term adaptive responses to electrical stimulation

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Predation, Feeding Preference of Threadsail Filefish Stephanolepis cirrhifer on Different Life Stages of Moon Jellyfish Aurelia aurita s.l. in the Laboratory (전 생활사 단계의 보름달물해파리(Aurelia aurita s.l.)에 대한 쥐치(Stephanolepis cirrhifer)의 포식과 먹이 선호도 실험)

  • Lee, Hye-Eun;Han, Chang-Hoon;Lee, Hye-Hyun;Yoon, Won-Duk
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.20 no.1
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    • pp.36-42
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    • 2015
  • To determine the predation rate of threadsail filefish, we conducted feeding experiment of threadsail filefish, Stephanolepis cirrhifer on different life stages (medusae, ephyrae, and polyps) of Aurelia aurita s.l. in the laboratory. All size groups of threadsail filefish actively preyed on moon jellyfish Aurelia aurita s.l. and predation rate was proportional to the wet weight of threadsail filefish. Average wet weight 0.5, 1, 2.2 g of threadsail filefish preyed on average $0.77{\pm}0.51g\;fish^{-1}h^{-1}$ of medusae. Average wet weight 150 and 344 g of threadsail filefish preyed on $9.26{\pm}1.61$ and $15.89{\pm}3.67g\;fish^{-1}h^{-1}$ of medusae respectively. In ephyrae and polyps, average wet weight 3.7 g of juvenile of threadsail filefish preyed on 100 ephyrae within 10 minutes and average wet weight 2.2 g of juvenile of threadsail filefish preyed on $5.73{\pm}0.59$ polyps $g^{-1}$ of fish $h^{-1}$. Whereas adults of threadsail filefish did not prey on polyps. In feeding preference experiments to elucidate whether threadsail filefish prey on moon jellyfish in the sea, adults of threadsail filefish preyed on mostly oysters (ca. 60%) and polychaetes (ca. 80%). Medusae were consumed only 2% of total. However, juvenile of threadsail filefish preyed on ephyrae and polyps as well as mysid shrimps. Besides, polyps were consistently consumed during the experiment. Although juvenile of threadsail filefish consumed all kinds of prey, they ceased feeding at temperatures below $11^{\circ}C$, which suggests that possibility of predation on ephyrae may be very low in the sea because ephyrae are released at low temperatures below $11^{\circ}C$ from March to April. Whereas polyps are inhabitable in all seasons in Korean coastal waters, juvenile of threadsail filefish may prey on polyps in the sea. These results suggest that removing moon jellyfish at polyp stage by using juvenile of threadsail filefish is the most effective way for extermination of moon jellyfish.