• Title/Summary/Keyword: 코티닌

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The Effects of Smoking Cessation Coaching Program based on Motivation Stage to Stop Smoking of Patients at a Public Hospital (금연동기단계에 따른 코칭프로그램이 환자 금연에 미치는 영향)

  • Kwak, Mi-Young;Hwang, Eun Jeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.4
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    • pp.188-198
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    • 2016
  • This study examined the effects of a smoking cessation coaching program based on the motivation stage applying the Transtheoretical Model to stop the smoking of patients in terms of the amount of smoking, nicotine dependence, CO level, and urine cotinine. The study design was a multi-repeat multiple repeat intermittent time series study with one-group, a pre-post design. The participants were 47 smoking patients (44 males and 3 females), who were treated at a public hospital in N city. The participants were 4 (8.51%) subjects in the action stage and 43 subjects (91.49%) in the preparation stage of the motivation stage. The coaching program intervention was conducted at the first day, second week, and 6th week. The smoking cessation maintenance of the subjects was checked at the 12th week. A chi-square test and t-test were used to analyze the data. The subjects in the action stage were kept under the condition of no smoking and nicotine dependence. After the program of subjects in the preparation stage, the amount of smoking, nicotine dependence, and CO level were significantly lower compared to the pre-test (p<.001). The findings suggest that the coaching program based on the motivation stage was effective in improving the smoking cessation for patients who smoke. On the other hand, the patients in the smoking cessation program may require much more financial assistance than those of healthy people. A greater workforce and budget will be needed for patients to stop smoking.

The Association between Environmental Tobacco Smoke and Periodontal Health: Finding from Korean National Health and Nutrition Examination Survey 2008~2009 (간접흡연과 치주건강의 관련성: 2008~2009 국민건강영양조사 자료분석 결과)

  • Kim, Jin Kyoung;Baek, Hye-Jin;Lee, Young-Eun;Song, Keun-Bae;Choi, Youn-Hee
    • Journal of dental hygiene science
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    • v.14 no.2
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    • pp.123-131
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    • 2014
  • Environmental tobacco smoke (ETS) or second hand smoke or passive smoking has become a well-known risk factor for various health hazards in nonsmoking adults as well as active smokers. In Korea, there have been few studies concerning about the impact of ETS on periodontal health. Therefore, the aim of this study was to investigate the association between exposure to passive smoking and prevalence of periodontitis using Korea National Health and Nutrition Examination Survey (KNHANES) in 2008 and 2009. The Fourth KNHANES data was employed from 2008~2009. The final sample size was 4,669 adults aged over 18 years, who were never-smoker and had the information about ETS both at home and in the workplace, urine analysis and periodontal examination by Community Periodontal Index (CPI). Periodontitis was defined as CPI codes ${\geq}3$. Data were analyzed using PASW Statistics 18.0. The sociodemographic and behavioral factors were adjusted as confounders. Overall, 17.1% (male 16.4%, female 83.6%) of the participants were exposed to ETS. The mean concentration of cotinine in those exposed ETS was significantly higher than that in unexposed people ($46.92{\mu}g/ml$ versus $19.34{\mu}g/ml$, p<0.001). Participants exposed to ETS were more likely to have periodontitis than those unexposed after adjusting for potential confounding variables. ETS is associated with the prevalence of periodontitis in Korean adults. This may suggest that patients with periodontitis or periodontal surgery should be protected from smokers or smoking places.

The Effects of a Self-esteem and Smoking Cessation Self-efficiency Improvement Program on Smoking High School Students (자아존중감 및 금연 자기효능감 증진 프로그램이 흡연 고등학생에게 미치는 효과)

  • Kim, Young-Sook
    • Research in Community and Public Health Nursing
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    • v.22 no.2
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    • pp.121-130
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    • 2011
  • Purpose: The purpose of this study is to understand the effects of a program to improve self-esteem and smoking cessation self-efficiency on smoking high school students' self-esteem, smoking cessation self-efficiency, amount of smoking, cotinine in urine, and carbon monoxide while exhalation. Methods: This research was conducted as a quasi-experimental pretest and posttest control and experimental group methodological comparison study. The subjects were 45 smoking high school students (Exp.=22, Cont.=23) in U City. Data were collected from October 19 to December 7, 2010, and analyzed using the SPSS/WIN 12.0 program by frequency, Mann-Whitney test, means, standard deviations, and Willcoxon signed rank test. Results: After the treatment, those belonging to the experimental group showed significantly increased self-esteem and smoking cessation self-efficacy and also showed decreased amount of smoking, cotinine in urine, and carbon monoxide while exhalation compared to the control group. Conclusion: The self-esteem and smoking cessation self-efficacy improvement program was effective in improving self-esteem and smoking cessation self-efficacy and in diminishing the amount of smoking, cotinine in urine and carbon monoxide while exhalation. Therefore, this program is recommended as a smoking cessation strategy for smoking adolescents.

Simultaneous Determination of Urinary Nicotine and Cotinine Using Gas Chromatography/Nitrogen-Selective Detection (기체 크로마토그래피/질소-선택적 검출을 이용한 소변 중 니코틴과 코티닌의 동시 분석)

  • 김희갑;박미진
    • Environmental Analysis Health and Toxicology
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    • v.16 no.4
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    • pp.181-188
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    • 2001
  • A gas chromatographic method was established for the simultaneous determination of urinary nicotine and cotinine. The analytes in basified urine containing a sufficient amount of Na$_2$S0$_4$were extracted into dichloromethane by vigorous shaking. Into the transferred organic phase was added a small amount of acidified methanol (0.5 N HCI in methanol), followed by concentrating the mixture to dryness using a mild stream of nitrogen gas. The concentrate was reconstituted with methanol and the final solution analyzed using the gas chromatograph equipped with the nitrogen-phosphorus detector. The reproducibility tests showed coefficients of variation less than 11% for both compounds. The percent recovery for both analytes ranged from 88 to 103%. The estimated method detection limits for nicotine and cotinine were 0.60 and 5.1 ng/mL, respectively. Extraction efficiencies for both nicotine and cotinine apparently declined without the addition of Na$_2$S0$_4$into the urine. Moreover, the absence of methanolic HCI in the extract resulted in almost complete evaporation of nicotine and partial loss of cotinine during the concentration process, indicating that the formation of nicotine-HCI and cotinine-HCI species is prerequisite to the suppression of the loss of both compounds.

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PC방에서의 간접흡연에 따른 요중 코티닌의 농도

  • 박용선;노영만;김치년
    • Proceedings of the Korean Environmental Health Society Conference
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    • 2002.04a
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    • pp.6-8
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    • 2002
  • Many adolescents stay long time in the PC game room and are exposed to much of tobacco smoke. To evaluate the effect of passive smoking in the PC game room, airborne nicotine concentrations and urinary cotinine concentrations were measured for 20 adolescents at 2 PC game rooms in Sung-nam city. And the subjects were interviewed for duration and time in PC game room and smoking pattern. Subjects are composed of each of 10 smokers(5 males and 5 females) and 10 non-smokers(5 males and 5 females). They stayed for three hours in the PC game room without smoking. Concentrations of nicotine in smokers and non-smokers were 129.72 $\mu\textrm{g}$/㎥ and 99.99 $\mu\textrm{g}$/㎥, respectively. Urinary cotinine concentrations were increased as time goes on after exposure to nicotine and showed maximum value at 9.45 hours after nicotine exposure and were 32.21 and 110.66 $\mu\textrm{g}$/L for non-smoker and smokers. Urinary cotinine has a tendency to be increased by passive smoking. Therefore, it is recommended that the effective control for indoor air quality and extensive research be needed to reduce nicotine concentration by passive smoking in the PC game room.

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Measurement of Urinary Nicotine and Cotinine Values in Smokers and Non-smokers (흡연자 및 비흡연자의 뇨중 니코틴 및 코티닌 함량)

  • 이문수;나도영;황건중
    • Journal of the Korean Society of Tobacco Science
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    • v.19 no.1
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    • pp.40-45
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    • 1997
  • This study was conducted to evaluate the personal effects of tobacco smoke and environmental tobacco smoke(ETS) by measuring the concentration of nicotine and cotinine in the urine. While 129 urine samples were being collected, Personal characteristics such as sex, age, number of years since a Person has been a smoker, average consumption number of cigarettes per day, and number of smoker in family were also surveyed. Collected urine samples were used for analysis of nicotine and cotinine by GC/NPD after Passing the extrelut column. In the urine of the smoker, the average contents of nicotine and cotinine were 5.38$\mu\textrm{g}$/ml and 3.14 $\mu\textrm{g}$/ml, respectively. The average contents of nicotine and cotinine were 0.18$\mu\textrm{g}$/ml and 0.07$\mu\textrm{g}$/ml in the urine of male non-smoker, respectively. The contents of nicotine and cotinine in the non-smoker's urine were dependent on sex and age. On the other hand, the contents of nicotine and cotinine in smoker's urine were dependent on average consumption amount of cigarettes per day. Also, there was a direct relation between nicotine levels in the smoker's urine and the average consumption number of cigarettes Per day of smoker. The Possible sources of nicotine and cotinine in the non-smoker's urine seemed to be caused by food, beverage and En, Our results indicate that the number of smoker in family had no effect on increasing nicotine and cotinine contents in the urine of non-smoker.

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Urinary cotinine concentration by passive smoking in the PC game room (PC방에서의 간접흡연에 따른 요중 코티닌의 농도)

  • Park Yong Sun;Roh Youngman;Kim Chi Nyon
    • Journal of Environmental Health Sciences
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    • v.28 no.1
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    • pp.11-20
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    • 2002
  • Tobacco smoke was confirmed as a human carcinogen by many research results. Because many adolescents stay long time in the PC game room, they are exposed to much of tobacco smoke. To evaluate the effect of passive smoking in the PC game room, airborne nicotine concentrations in 2 PC game rooms in Sung-nam city and urinary cotinine concentrations were measured for 20 adolescents. And the subjects were interviewed for duration and time in PC game room and smoking pattern. Subjects are composed of each of 10 smokers(5 males and 5 females) and 10 nonsmokers(5 males and 5 females). They stayed for three hours in the PC game room without smoking. Concentrations of nicotine in smokers and nonsmokers were 129.72 $\mu$g/$^3$ and 99.99 $\mu$g/m$^3$, respectively. Urinary cotinine concentrations were increased as time goes on after exposure to nicotine and showed maximum value at 9.45 hours after nicotine exposure and were 32.21 and 110.66 $\mu$g/L for nonsmoker and smokers. The more using time and frequency in PC game room, the higher urinary cotinine maximum concentration and the longer using duration, also the more increase urinary cotinine concentration. Urinary cotinine has a tendency to increase by passive smoking. Therefore, it is recommended that the effective control for indoor air quality and extensive research be needed to reduce nicotine concentration by passive smoking in the PC game room.

Urinary Exposure Levels of Cotinine and Influence Factors among Non-smokers in Korean Adults - Korean National Environmental Health Survey (2009-2017) - (우리나라 성인 중 비흡연자에 대한 코티닌 노출수준 및 영향요인 분석 - 국민환경보건 기초조사(2009-2017) 결과 -)

  • Jeon, Hye Li;Hong, Sooyeon;Joo, Youngkyung;Kwon, Young Min;Jung, Sun Kyoung;Lee, Chulwoo;Yu, Seung Do;Yoo, Jiyoung
    • Journal of Environmental Health Sciences
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    • v.46 no.2
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    • pp.214-223
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    • 2020
  • Objectives: The aim of this study is to identify temporal trends in urinary cotinine levels and exposure factors among Non-smokers in Korean adults. Methods: Biological samples and questionnaire data were collected from representative Korean adults recruited in the Korean National Environmental Health Survey from 2009 to 2017. Multiple regression analysis was performed to determine the factors affecting urinary cotinine concentrations of non-smokers. Results: The urinary cotinine levels of Korean non-smokers decreased in Cycle 2 (1.04 ㎍/L, 2012-2014) compared to Cycle 1 (1.93 ㎍/L, 2009-2011) but increased slightly in Cycle 3 (1.37 ㎍/L, 2015-2017). Among the diverse variables, the main factors of cotinine exposure were secondhand smoke exposure and the presence of smokers in the family. Conclusions: The results of this study identified temporal trends in cotinine exposure among non-smokers in the Korean adult population. These findings will be used to develop further assessment and environmental health policies on secondhand smoke exposure.

Smoking Influence and Psycho-social Factor of Participant in a Smoking Cessation Program (금연프로그램 참여자의 흡연 영향 및 사회심리적 상태)

  • Kim, Gwang-Suk;Lee, Young-Ja;Lee, Chung-Yul
    • Journal of Korean Public Health Nursing
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    • v.21 no.1
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    • pp.37-45
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    • 2007
  • Purpose: A diverse range of measurement methods to evaluate the effect of smoking is more powerful than using a single measure. The objectives of this study were to examine the relationships among smoking pack year, self-reported smoking dependence, and urinary cotinine levels, and to investigate the psychological variables in working men. Method: In this cross-sectional study, we surveyed men working in an electronic company who participated in a smoking cessation program. Among 57 men who completed questionnaires, 25 participate in a test for cotinine levels. Results: Smoking pack year was significantly and positively correlated with the FTND-K (Korean version of Fagerstrom test for nicotine dependence) sum scores (r=0.631, p=0.000) and with the levels of urine cotinine (r=0.463, p=0.023). The relationship between FTND-K sum scores and urinary cotinine levels was also significantly positive (r=0.639, p=0.001). Those with higher social support, especially family support, tended to perceive a higher self-efficacy to smoking cessation. Conclusion: These findings suggest that self-reported smoking pack year and nicotine dependence in working men may be a valid way to evaluate the effect of smoking. A supportive family may influence smoking cessation in working men as it increases self-efficacy to avoid smoking.

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The Effect of Life Smoking Cessation Program- multidisciplinary approach (다 학제간 접근방식을 이용한 생활금연 프로그램개발과 그 효과에 관한 연구)

  • 신성례;이동섭;박정환
    • Journal of Korean Academy of Nursing
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    • v.30 no.1
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    • pp.110-121
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    • 2000
  • This study was designed to develop the life moking cessation program with multidisciplinary approach using the Bandura's theory of self-efficacy and confirm the effect of it on the self-efficacy and smoking amount in college students. For this purpose non-equivalent control group, pretest-posttest design was used. The participating subjects in this study were 46 male college freshmen, 23 in experimental and 23 in control group. The experimental group received the 8 sessions of lecture and small group discussions for 4 weeks and a telephone coaching program for a period of 8 weeks. The control group received 5 sessions of lecture without further treatments. The data was collected from March 15 to June 11, 1999, and analysed by SAS/PC program with $\chi$$^2$test, simple t, paired t test. The results were as follows. 1. The score of self-efficacy was significantly increased over time in the experimental group than those of the control group. 2. The amount of urine cotinine was decreased over time in the experimental group, number of cigarettes smoked a day were significantly decreased, and they were significantly less than those of the control group. In conclusion it was found that the Life Smoking Cessation Program with Multidisciplinary Approach was an effective nursing intervention for increasing self efficacy and reducing the amount of smoking in male college students. Therefore, future smoking cessation programs should always consider the concept of self-efficacy and ways to positively reinforce it.

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