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Anti-Wrinkle Effects of Korean Rice Wine Cake on Human Fibroblast (양조 부산물인 주박의 주름개선 효과)

  • Yoo, Jung-Min;Kang, Yeo-Jin;Pyo, Hyeong-Bae;Choung, Eui-Su;Park, Shin-Young;Choi, Ji-Ho;Han, Gwi-Jung;Lee, Choong-Hwan;Kim, Tack-Joong
    • Journal of Life Science
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    • v.20 no.12
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    • pp.1838-1843
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    • 2010
  • Skin aging is related to genetic and environmental factors (e.g., gene mutation and UV radiation respectively). To develop a new anti-wrinkle cosmetic or functional food by using Korean rice wine cake, we examined the effects of Korean rice wine cake, a brewery byproduct, on antioxidant effect, collagen synthesis and expression of MMP-1. Interestingly, we found that Korean rice wine cake has the ability to promote scavenging activity of DPPH radical. We also found that the cell proliferation and synthesis of collagen in HS27 cells was increased by Korean rice wine cake in a concentration-dependent manner. However, elastase inhibitory activity was not changed. In addition, the expression of MMP-1 was inhibited by Korean rice wine cake in a concentration-dependent manner. All these results suggest that Korean rice wine cake can be effectively used for the prevention of wrinkles in human skin.

The effects of strength training on the change of ground reaction force for the children with Down syndrome (근력 훈련이 다운증후군 아동의 지면반력의 변화에 미치는 영향)

  • Lim, Bee-Oh;Han, Dong-Ki
    • Korean Journal of Applied Biomechanics
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    • v.12 no.2
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    • pp.1-16
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    • 2002
  • The purposes of this study were to investigate the effects of strength training on the change of ground reaction force for the children with trisomy 21 Down syndrome. The subjects of this study were consisted of eight elementary school students with Down syndrome who participated in the strength training. The strength training was administered by six items such as squat, leg curl, leg extension, toe raise, sit-ups, and hyperextension. For strengthening muscle, each group also was treated by walking for 8 weeks, three times a week, 10-15RM, 3sets, which was based on the principle of progressive overload. For inquiring the effect of strength training, the ground reaction force variables were measured in two phases : before-training and 8 week-after training. The gait of each subject was acquisition using 2 AMTI force platforms set at 100 frequency. The results of this study were as follows: The pattern of vertical, antero-posterior and medio-lateral forces, trajectory of net COP and the timing ratio of reaching the each events were shown variously. So, it is not easy to explain these variables clearly. As the result of strength training, these variables were changed. However, the results of within subjects differ greatly, there was no difference statistically.

Evaluation of Recombinant Human Lactoferricin Culture as a Substitute for Antibiotic in Pig Starter Diets (이유자돈사료에 항생제를 대체하기 위한 재조합 인간 락토페리신 컬처의 평가)

  • Hong, J.W.;Kim, I.H.;Hwang, I.H.;Lee, J.H.;Kim, J.H.;Kwon, O.S.;Lee, S.H.
    • Journal of Animal Science and Technology
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    • v.45 no.4
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    • pp.537-542
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    • 2003
  • Sixty [(Duroc${\times}$Yorkshire)${\times}$Landrace] pigs (7.63$\pm$0.41kg average body weight and 25-d average age) were used in a 20-d growth assay to determine the effect of dietary recombinant human lactoferricin culture (RHLC) supplementation on growth performance, digestibility and plasma IgG concentration in weaning pigs. Dietary treatments included 1) Negative control (NC : without antibiotic), 2) Positive control (PC : NC diet + 0.1% chlortetracycline), 3) RHLC0.3 (NC diet + 0.3% RHLC), 4) RHLC0.5 (NC diet + 0.5% RHLC). No differences were found among treatments in average daily gain (P>0.05). ADFI of pigs fed RHLC0.3 diet was higher than that of pigs fed PC diet (P<0.05). However, pigs fed RHLC0.5 diet had improved gain/feed compared to pigs fed PC diet. Pigs fed PC and RHLC diets showed significantly increased dry matter digestibility compared to pigs fed NC diet (P<0.05). There was no significant difference in plasma IgG concentrations (P>0.05). The supplementation of RHLC in starter pig diets appears to be an alternative to antibiotics.

A Study on the Corrections in Selected Korean and American Newspapers (한국과 미국 일간신문의 정정보도 기사 비교연구: 조선일보, 한겨레신문, 뉴욕타임스, 샌프란시스코 크로니컬을 중심으로)

  • Im, Yang-June
    • Korean journal of communication and information
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    • v.37
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    • pp.204-236
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    • 2007
  • This study explores the corrections on the Korean and the U. S. daily newspapers for the characteristics and differences through the content analysis. For the research, Chosun Ilbo, Hankyoreh Shinmun, The New York Times and The San Francisco Chronicles are selected. The main differences between the Korean and American newspapers are as follows: Firstly, the average number of newspaper errors in Korean dailies are as half as little of those in the U. S. dailies. Secondly, regarding the subcategory of mistakes, the largest thematical number is the societal matters(36.0%), followed by politics(18.3%) and economy(12.1%) for the Korean newspapers. By contrast, errors in culture(17.4%) is the most frequently made by the American newspaper reporters and editors, followed by lifestyle(8.6%), and sports(7.0%). Thirdly, in terms of content of mistakes, errors in names(26.2%) that occurred the most, followed by misidentifications(18.1%) and misattribution(15.8%) for the Korean dailies; the errors in numbers(33.7%), spelling and typographical errors(12.1%) and date(5.6%) for the U. S. dailies. Fourthly, one of the critical reasons that mistakes occurred because Korean reporters are lack of double checking the stories; the U. S. reporters simply by overlooking the articles. Finally, the Korean newspapers make use of only two kinds of correction formats, while the U.S. newspapers use six different correction formats for their newspaper readers.

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A Convergence Study on the Core Competencies of students: G university (G 대학 대학생 핵심역량 설정에 관한 융합연구)

  • Kim, Chang-Gyu;Jang, Kee-Duck;Chun, Yeol-Eo
    • Journal of the Korea Convergence Society
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    • v.9 no.7
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    • pp.77-86
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    • 2018
  • This research is based on core competency in order to provide diverse educational opportunities and to train compatible human resources according to industrial change. The research set up the core competency of university students according to document research and the importance of core competency of students, professors, faculty and parents. As a result, a total of 14 competencies were deducted by importance and validation from enrolled students, graduated students and professors. A total of 5 core competencies and 14 detailed competencies were deducted. Creativity, problem solving ability, self-directed overall problem solving abilities, expertise ability, data processing ability, technology application according to industry, consideration and serving character, community service, communicational ability, self-management, inter personal relationship, foreign language ability, global, leadership and competence were the 14 elements of this research. Based on the result of this study, it is necessary to improve the competence of university students by applying them to the curriculum development and operation and to find out the extent of the students competence enhancement through the development of future capacity measuring tools.

Bioactive Component Analysis and Antioxidant Activity in Fresh Sprout of New Kalopanax septemlobus Cultivar (음나무 신품종 새순의 유용물질 함량분석과 항산화활성)

  • Song, Jeong-Ho;Kim, Hyeusoo;Kim, Moon-Sup;Kim, Sea-Hyun;Lee, Jin-Tae
    • Journal of Korean Society of Forest Science
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    • v.104 no.3
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    • pp.397-402
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    • 2015
  • This study was carried out to analyze the nutritional composition, bioactive compound and antioxidant activity in fresh sprout of 3 new Kalopanax septemlobus cultivars. Cheong-San, Cheong-Song and Cheong Sun 1 had largest carbohydrate (52.90, 53.12, 55.28%), crude protein (34.23, 31.33, 33.58%) in the proximate composition and had largest K (2.29, 2.22, 2.23%) followed by Ca (0.44, 0.34, 0.37%), Mg (0.24, 0.19, 0.19%) in the mineral contents. Three new cultivars contained a total of 26, 25 and 28 different kinds of amino acids, respectively and the number of essential amino acid is 6, 6 and 7 species, respectively. Also, Cheong-San had higher total polyphenol contents and Cheong-Song had higher total flavonoid contents. DPPH free radical scavenging activity of 70% ethanol, water extracts of Cheong-San and Cheong-Song is higher than others at 100 ppm. In the ABTS radical cation decolorization activity, 70% ethanol extract of Cheong Sun 1, water extract of Cheong-San and Cheong-Song are higher activity than others and all samples have more than 85% ABTS racial cation decolorization activity at 500 ppm. Our results suggest that new K. septemlobus cultivars possess good antioxidant capacities with a high nutritional value and might have potential applications in the food and medical industries.

Indol-3-Carbinol Regulated Tight Junction Permeability and Associated-Protein Level and Suppressed Cell Invasion in Human Colon Cancer Cell Line, HT-29 (인돌 (Indol-3-Carbinol)이 인체대장암세포 HT-29 세포의 투과성 밀착결합조절과 세포 침윤성 억제에 미치는 영향)

  • Kim, Sung-Ok;Choi, Yung-Hyun;Choe, Won-Kyung
    • Journal of Nutrition and Health
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    • v.41 no.1
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    • pp.13-21
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    • 2008
  • To determine whether indol-3-carbinol (BC, $C_9H_9NO$), an autolysis product of a glucosinolate and a glucobrassicin in vegetables, regulated tight junction proteins (TJ) and suppressed cell invasion in colon cancer cells, this experiment was performed. Our results indicate that I3C inhibit cell growth of HT-29 cells in a dose (0, 50, $100{\mu}M$) and time (0, 24 and 48h) dependent manner. Using the wound healing and matrigel invasion study, respectively, BC inhibits the cell motility and invasion of the ovarian cancer cell line. The TEER values were increased in HT-29 cells grown in transwells treated with BC, reversely, paracellular permeability was decreased in those of condition. Claudin-1, claudin-5, ZO-1 and occuldin have been shown to be positively expressed in HT-29 coloncancer cells. I3C occurs concurrently with a significant decrease in the levels of those of proteins in HT-29 cells. But E-cadherin level in the HT-29 was increased by I3C. The reduction of claudin-1 and claudin-5 protein levels occurred post-transcriptionaly since their mRNA levels are no difference by I3C. Therefore, our results suggest that I3C may be expected to inhibit cancer metastasis and invasion by tighten the cell junction and restoring tight junction in colon cancer cell line, HT-29.

A study on the Policies for the Promotion of Korean Literature seen through Manhae Festival (만해축전을 통해서 본 한국문학진흥정책에 관한 연구)

  • Lee, Won-Oh;Rhyu, Ji-Sung;Kim, Ji-Won
    • The Journal of the Korea Contents Association
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    • v.15 no.12
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    • pp.234-246
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    • 2015
  • When the Information age led by media comes, The literature yielded its prominence to visual media, and the Korean literature also faced a crisis, prompted by decreased demand for it. In this reality, literature festivals which have increased rapidly since 1995 and currently number at least 110, when the local government system was launched, played an important role in promoting literature to the society. This thesis has selected Manhae Festival, one of the most vibrant and successful, as the case study to analyze its present status and accomplishments to derive ways for improvement which can be used to promote policies on literature. Manhae Festival which celebrates Manhae Han Yongun, a poet and an independence activist, also became one of the top literature festivals through Manhae Grand Awards and various cultural, art and academic events, despite being held in Inje County, Gangwon Province, a remote location. Based on this study, in the near future, Manhae Village, as a complex cultural venue, as a If we can make the place into complex cultural space and with additional policy support by gaining political supports like designation as Slowcity and special zone of culture and tourism, and pursuing glocalization by making Manhae into a star brand, Manhae Festival will cement its current position as a successful literary festival. It has very meaningful since most of literature festivals operate in small scale. Now, we need to develop literature festivals into local ones by attracting larger popularity. Meanwhile, a more comprehensive study, in the future, is needed with special emphasis on successful literary policies and their precedents in other countries.

Bioactivity and Chemical Composition of the Essential oil of Tea Tree (Melaleuca alternifolia) (티트리 에센셜오일의 생물활성 및 주요 성분 분석)

  • Yang, Seun-Ah;Jeon, Sang-Kyung;Lee, Eun-Jung;Im, Nam-Kyung;Jung, Ji-Young;Lee, In-Seon
    • Journal of Life Science
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    • v.18 no.12
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    • pp.1644-1650
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    • 2008
  • The essential oil of tea tree (Melaleuca alternifolia) is widely used in traditional Australian medicine for skin lesions and infected injuries. In the present study, we investigated the chemical composition, cytotoxicity and its biological activities. The composition of the oil was analyzed by GC-MS. ${\beta}$-Terpinene (20.87%), ${\alpha}$-pinene (17.60%), p-cymene (11.23%), 3-carene (10.40%), trans-anethole (8.47%) and limonene (4.65%) were the major components in the oil. The results tested by MTT assay indicated that the oil showed no cytotoxic effect, at concentrations up to 5%, for less than 3h. The antiradical capacity was evaluated by measuring the scavenging activity of the essential oil on the 2,20-diphenylpicrylhydrazyl (DPPH) and 2,2'-azino-bis 3-ethyl benzothiazoline-6-sulfonic acid (ABTS) radicals. The oil was able to reduce the both radicals dose-dependently, and the concentration required for 50% reduction ($RC_{50}$) against ABTS radicals ($1.6{\pm}0.02%$) was slightly lower than DPPH radicals ($2.6{\pm}0.29%$). The direct contact and vapor-phase antibacterial activity of the oil were also evaluated using disc diffusion method against Staphylococcus aureus, Streptococcus mutans, Listeria monocytogenes, Acinetobacter baumannii, Escherichia coli, and Vibrio parahaemolyticus. All the Gram-negative bacterial strains tested showed more sensibility to the oil than the Gram-positive strains when compare to the effect of gentamycin. On the other hand, the vapor phase of the essential oil against S. aureus exhibited strongest inhibitory effect.

Modeling of Circulation for the East Sea Using Reduced Gravity Models (감쇠중력 모형을 이용한 동해의 순환모델링)

  • Choi, Byung-Ho;Wang, Ou
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.9 no.3
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    • pp.105-114
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    • 1997
  • Wind is one of the main forcing contributing the circulation of the East Sea. By using 1.5-layer and 2.5-layer reduced gravity models, circulation in the East Sea is simulated. The bifurcation of the Tsushima Warm Current (TWC), the separation of East Korea Warm Current (EKWC) from the east coast of Korea, the Nearshore Branch of TWC, and the cyclonic gyres stretched from the East Korea Bay to the northern half of the East Sea are compared well with the schematic map. The features of the upper and the lower layer are very similar except for those of the central region. The Polar Front is the separating line of two different features. The main feature of northern part of the East Sea, north of the Polar Front is cyclonic gyres, which are composed of three cyclonic gyres in most seasons. North Korean Cold Current (NKCC) and Liman Cold Current (LCC) are the nearshore part of these cyclonic gyres. In the south of the Polar Front the current systems of both layers are anticyclonic in most seasons, except that those of the upper layer in winter and spring are not anticyclonic. Along the coast of Korea and Russia, the velocity structure is barotropic, while that of the central region is baroclinic. The effects due to the seasonal variations of wind stress and local Ekman suction/pumping are studied by imposing the domain with modified wind stress. which is spatial mean with temporal variations and temporal mean with spatial variations. It is found that the local Ekman suction/pumping due to wind stress curl is important to the formation of the cyclonic gyres in the western and the northwestern region of the East Sea.

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