• Prospectives of Industrial Chemistry
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• v.22 no.6
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• pp.13-25
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• 2019

건강한 미래, 건강 사회 구현과 함께 질병 진단, 치료, 예방에 대한 관심이 급증하고 있다. 이에 따라 적시적기에 질병을 치료하고 예방하기 위한 건강 검진용 바이오센서 수요가 증가하였고 이에 따라 바이오센서 시장은 전세계적으로 급격히 확장되고 있다. 혈액 샘플을 기반으로 한 검진 방법이 보편적이지만 최근에는 고감도 센서 개발에 따라 소변, 침, 눈물 등과 같은 체액으로도 검진이 가능한 환자 친화적 비침습 센싱 방법도 활발하게 연구되고 있다. 이러한 센서 시장 패러다임의 변화 및 급속한 발전은 마이크로, 나노 재료 제작과 분석 기술 발전으로 체액 내 존재하는 나노 크기의 바이오 마커(단백질, 유전자, 펩타이드, 사이토카인)를 검출하는 소형화된 고감도의 센서를 개발할 수 있게 되었고 그 결과 화학, 물리, 재료, 의약 등 다양한 학문 분야에서 다양한 형태의 센서가 활발히 보고되었다. 본 기고문에서는 바이오센서용 소재 중에서 나노입자에 집중하여 첨단 센서 구현을 위해 사용된 입자의 종류, 센서 내에서의 입자의 역할을 소개하고 나노입자의 광학적, 물리적 특성에 따른 타겟 물질 검출 방법 및 동향에 대해 논의하고자 한다.

• The Journal of Korean Medicine
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• v.45 no.1
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• pp.240-250
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• 2024

Objectives: The purpose of this study is to report a case of Korean medicine treatment accompaning myofascial trigger-point accupuncture for severe & persistent lower urinary tract symptoms after radical prostatectomy. Materials and Methods: A prostate cancer patient with severe & persistent lower urinary tract symptoms after radical prostatectomy conducted 26 months ago, was treated with Korean medicine accompaning myofascial trigger-point accupuncture. The International Prostate Symptom Score(IPSS), the IPSS Quality of Life(IPSS-QoL) and the Overactive Bladder Symptom Score(OABSS) questionaires were administered to evaluate the effect of treatment for lower urinary tract symptoms. Results: After 5 month treatment with Korean medicine accompaning myofascial trigger-point accupuncture, IPSS, IPSS-QoL and OABSS progressed from 28 to 8, from 5 to 2 and from 12 to 4 respectively. Conclusion: This case study suggests that Korean medicine accompaning myofascial trigger-point accupuncture may contribute to treat severe & persistent lower urinary tract symptoms after radical prostatectomy.

• Journal of Acupuncture Research
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• v.22 no.3
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• pp.93-104
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• 2005

Objective : Because the cause and etiology of chronic headache are not yet fully explained, the treatment of this symptom is not simple. In order to study the effectiveness of East-West pain treatment on chronic headache, we evaluated its effect of pain alleviation and quality of life improvement on chronic headache patients who were treated with nerve block and acupuncture, and only acupuncture for eight weeks. Methods : 92 clinical experiment participants were gathered and through a questionnaire patients who experienced headache for more than 4 hours a day and more than 15 days per month were qualified as chronic headache patients. The qualified patients were classified into two groups, nerve block and acupuncture group(EW group, n=49) and acupuncture group(E group, n=43). Treatment was applied 2 times a weeks for 8 weeks. The acupoints, GV20, HN23, ST8, HN46, TE17, GB20, LI20O, LI11, LI14, ST36, and LR3 were stimulated for 20 minutes. The effects of two groups were analyzed using VAS scores and BPI(Brief Pain Inventory).

• The Journal of Internal Korean Medicine
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• v.41 no.1
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• pp.29-43
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• 2020

Objectives: The purpose of this study was to summarize current research trends and results regarding acupuncture treatment for hypertension. Methods: Articles published from 2009 to 2019 were searched on domestic databases (OASIS, NDSL, RISS) and PubMed using the keywords 'Hypertension', 'Hypertensive', 'Acupuncture', 'EA' (electroacupuncture), 'Autonomic nervous system', 'ANS', 'CVD' (cardiovascular disease), '고혈압', '침', '전침', and '자율신경계'. The studies were analyzed according to the year, type of study (domestic or foreign articles, nationality of the first author), acupuncture type for human and animal studies, BP (blood pressure) measurement, and acupuncture intervention. Results: In total, 21 articles were selected. There were 8 randomized controlled trials (RCTs), 3 non-randomized controlled trials (nRCTs), 2 before-after studies, 1 case series, and 7 animal studies. Manual acupuncture (11 articles) was most frequently used, and ST36 (足三里) was most frequently used in human studies. In 18 of 21 articles, acupuncture was reported as effective in lowering systolic blood pressure (SBP) or diastolic blood pressure (DBP) in hypertensive patients. Conclusions: Acupuncture treatment for hypertension is deemed useful. Further studies are necessary for application of acupuncture therapy in clinical practice.

• Journal of the Korean Society for Precision Engineering
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• v.26 no.4
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• pp.114-119
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• 2009

In this research, heat-acupuncture needle was coated with $Al_2O_3$ by applying a plasma spray coating method to prevent a skin burn. $Al_2O_3$, which is one of the representative bioceramics, does not have an influence on the chemical change in the body system. The ceramic coating thickness was about $100{\mu}m$. The experiments of heat conduction were performed for uncoated needle and coated needle. The results showed that the surface temperature of needle decreased as the needle was coated with $Al_2O_3$. The surface temperature of uncoated needle was about $48^{\circ}C$, while that of needle coated with $Al_2O_3$ was about $39^{\circ}C$.

• The Journal of Internal Korean Medicine
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• v.40 no.3
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• pp.557-565
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• 2019

Objectives: This study investigated the effect of local acupuncture point stimulation and the application of a topical herbal mixed heating cream in a chronic cough patient who had not responded to various medications for more than a few months. Methods: An 81 year-old female patient who was suspected to be suffered from Upper Airway Cough Syndrome (UACS) was examined. The patient was treated with local acupuncture point stimulation and the application of a topical herbal mixed heating cream. We used the Leicester Cough Questionnaire, Cough-Specific Quality-of-Life Questionnaire, and Verbal Numerical Rating Scale to assess the patient's respiratory symptoms. Results: Local acupuncture point stimulation and the application of a topical herbal mixed heating cream resulted in the improvement of cough symptoms. The quality of life due to the alleviation of symptoms also significantly improved. Adverse effects were not observed. Conclusions: This study suggests that local acupuncture point stimulation and the application of a topical herbal mixed heating cream may be an effective therapy for the treatment of chronic cough in patients with UACS.

• Journal of the Korean Orthopaedic Association
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• v.55 no.6
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• pp.550-553
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• 2020

Acupuncture, which is a procedure of inserting needles in a specific portion of the body to control pain, is conducted widely. The procedure is considered relatively safe because of its minimal side effects and low occurrence (1 in 200,000). On the other hand, its side effects include neurological damage, infection, hematoma, emphysema, etc. The authors report a case of cervical neurological damage that occurred after an acupuncture procedure.

• Korean Journal of Acupuncture
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• v.34 no.3
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• pp.179-184
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• 2017

Objectives : Despite the applicability of Korean Medicine(KM) treatments for facial asymmetry, no relevant study has been reported. In this case report, we report the effect and safety of KM treatments on facial asymmetry by mandibular lateral displacement. Methods : Three patients suffering from facial asymmetry received twelve KM treatment sessions composed of Motion Style Treatment(MST), Yinyang Balance Appliance(YBA) of Functional Cerebrospinal Therapy(FCST), and Instrument Assisted Soft Tissue Mobilization(IASTM). The photos of each patient were taken before and after the treatment. And four primary reference lines were assessed before and after the treatment. Results : All subjects were improved after KM treatments on photos. However, no statistical significance was observed. Conclusions : This case report is the first to introduce the effect of KM treatments on facial asymmetry. Further well-designed, randomized, placebo-controlled trials are needed to verify these results.

• The Journal of Internal Korean Medicine
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• v.45 no.1
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• pp.111-118
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• 2024

This case report highlights the efficacy of traditional Korean medicine in treating chronic levator ani syndrome. A 47-year-old male suffered from chronic anorectal pain for 14 years. Over the last 5 months, the severity and frequency of the pain increased, and he was unresponsive to Western medicine and acupuncture outside Korea. The patient reported moderate anorectal pain from early morning until midday, affecting daily efficiency and concentration. The pain was triggered by defecation and alleviated by lying down. He was diagnosed with levator ani syndrome related to "cold symptoms of the liver and kidney - Yin", for which modified Nangan-jeon was prescribed. Indirect moxibustion (CV4, Ki1), Aconitum ciliare Decaisne pharmacopuncture (GV1, BL33), and acupuncture (HT7, ST36, SP6, LR3, LI4) were also administered weekly. After 8 weeks, the anorectal pain decreased by 2 points on a numeric rating scale, leading to patient satisfaction and return to his home country.

• The Journal of the Korean bone and joint tumor society
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• v.9 no.1
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• pp.84-92
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• 2003

Purpose: To report two cases of bone tumors other than osteoid osteoma in the proximal femur and treated with percutaneous high frequency radioablation method. Cases: We reviewed two cases with intracortical chondroma and enchondroma in the femoral head retrospectively. The patient with intracortical chondroma was a thirty one year old woman and had suffered right hip pain of 1 year duration. The lesion was located in the head of right femur and treated with CT guided percutaneous high frequency radioablation after needle biopsy under general anesthesia. The symptom was gone immediately after the procedure and was discharged postop. 1 day. 15 months has passed without symptom recurrence. Second case having enchondroma, was 56 year old woman complaining of gluteal area pain for 3 months. Radiologic evaluation showed osteolytic lesion with sclerotic rim on the inferior portion of the left femoral head. She received a same therapy with CT guided radiofrequency ablation following needle biopsy. She reported dramatic pain relief after the procedure and was discharged postop. 1 day. No symptom has occurred for 3 months until now. Conclusion: We present 2 cases of bone tumor occurred in the hip joint area other than osteoid osteoma which were treated with CT guided radiofrequency ablation.