• Proceedings of the Korean Society for Rock Mechanics Conference
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• 2007.10a
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• pp.137-146
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• 2007

해저 지하 구조물을 시공할 경우는 높은 수압 및 침투압 등의 영향이 무시될 수 없으므로 지하저장 공동의 정확한 거동평가를 위해서는 수리-역학적 해석이 수행되어야만 한다. 또한, 실무에서는 암반이완하중을 고려하여 터널의 콘크리트 라이닝을 설계하며, 이를 위해 이완하중고를 터널 주변의 국부안전율 분포를 이용하여 수치해석에 의해 산정하는 방법이 제안된바 있다. 따라서 본 연구에서는 해저터널을 대상으로 수리-역학적 연계해석 시 국부안전율을 이용한 이완하중고 산정 기법의 타당성을 살펴보았다. 이를 위해 3등급 암반을 대상으로 숏크리트 수리특성을 이용한 유도배수방법과 집수정의 펌핑을 이용한 유도배수방법을 이용하여 이완하중고를 산정하고 적용성을 비교하였다. 연구 결과 연계해석 시 해저시설물의 안전율 및 이완하중고를 정확하게 산정하기 위해서는 집수정의 펌핑을 이용하여 유도배수하는 모델링 방법이 보다 정확하고 일관성 있는 결과를 얻을 수 있었다.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.05b
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• pp.1189-1193
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• 2005

해안지역 지하수 개발에 있어 이익을 최대화하는 동시에 개발로 인한 부정적 영향을 최소화하는 4단계 확보방안이 제시되었다(박남식 등, 2004). 4단계 확보 방안 중 처음 3단계 방안에 대한 의사 결정 지원 도구역할을 할 수 있는 해안지하수 최적개발 모델이 개발되었다(박남식 등, 2003, 홍성훈, 2004). 개발된 모델은 대상 관정의 양수량과 위치에 대한 최적해 뿐만이 아니라 해수침투를 방지 및 제어에 대하여서도 최적화가 가능하다. 본 연구에서는 개발된 모델의 민감도 분석 결과를 다루고 있다. 민감도 분석의 목적은 불확실성을 내포하고 있는 대수층의 주요 매개변수, 경계조건 등에 의해 야기될 수 있는 모델의 불확실성을 정량화하는 것이다(Anderson 등, 1992). 따라서 민감도 분석은 모델의 특성에 대한 이해뿐만이 아니라 모델에 있어 매개변수들의 영향 및 거동을 고찰하는데 중요한 연구이다. 구축된 최적개발 모델을 이용하여 수리전도도, 함양율, 대수층 두께와 같은 주요 매개변수들이 최적양수량 그리고 관정의 최적위치에 미치는 영향을 고찰하였다. 그 결과 회수율은 함양율 증가에 따라 증가하는데, 높은 수리전도도에서는 함양율과 선형관계를, 낮은 수리전도도에서는 비선형관계를 보였다. 관정의 최적위치는 수리전도도에 가장 민감하였으며, 함양율 증가에 따라 해안으로 이동하였다. 마지막으로 최적개발량과 최적위치를 동시에 고려할 경우 최적개발량만을 고려한 경우보다 회수율이 향상되었다.

• Journal of the Korean Wood Science and Technology
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• v.45 no.1
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• pp.107-115
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• 2017

In this study, the surface check reduction effect of preservative-treated Korean larch round-wood was investigated by applying three physical treatments, such as incising, kerfing, and kiln-drying. Moreover, the possibility of long-term service life was also checked by comparing the depth of surface check and the penetration depth of preservative. A rapid gradient of wood moisture content between surface and center causes a surface check. Thus, the effect of reducing surface check was carried out at the lowest equilibrium moisture content (EMC) condition, temperature ($2^{\circ}C$), humidity (44.6%), in outdoor locations in Korea until the test specimens reach to the 8.6% EMC. As a result, the preservative-treated specimens without incising, kerfing, kiln-drying (Type C) could not ensure the long-term service life due to a large surface check. Because the surface check depth of all specimens was deeper than the penetration depth of preservative. In case of the incising treated specimens (Type I), 80% of them, the depth of surface check was not deeper than the penetration depth of preservative. However, when a kerfing was additionally treated (Type B), a possibility of happening deeper surface check than penetration depth of preservative was increased rather than Type I.

• Journal of the Korean Geotechnical Society
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• v.33 no.11
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• pp.73-82
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• 2017

Recently, offshore bucket cut-off walls were developed to solve several problems in conventional offshore cut-off walls. In this study, a numerical analysis was carried out to investigate the seepage stability of offshore bucket cut-off walls. The ground was assumed as uniform homogeneous sand and steady state flow conditions were applied. The flow condition was compared among 2-dimensional flow (2-D), 2-dimensional concentrated flow (2-DC), and axisymmetric flow. The analysis results showed that the seepage velocities in axisymmetric flow were about 1.5 and 2 times larger than those of 2-DC and 2-D flow conditions, respectively. Thereafter, the axisymmetric flow condition was applied because the seepage flow was concentrated toward the center of the circular-shaped wall. A parametric study was performed varying bucket radius, penetration depth, total head difference between in and outside of the wall. The exit gradient, which used for the calculation of piping stability, decreased with increase of the penetration depth and bucket radius. Design charts were proposed to estimate the factor of safety and the exit gradient at various analysis conditions. Finally, the design equation was proposed to calculate the exit gradient for the preliminary design of the bucket cut-off wall.

• Journal of The Korean Society of Grassland and Forage Science
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• v.38 no.4
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• pp.320-324
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• 2018

In this study, we examined effect of sperm penetration of oocytes after in vitro fertilization (IVF) with cauda epididymal spermatozoa in Hanwoo bull after feeding of timothy hay. One testicle with epididymides was castrated from one Hanwoo bull (14 months of age) and spermatozoa recovered from cauda epididymis and cryopreserved. As control, frozen Hanwoo semen was used. Matured cumulus oocyte complexes were co-incubated with frozen-thawed cauda epididymal spermatozoa for 12 or 18 hours. After IVF, presumptive zygotes were cultured in modified synthetic oviductal fluid. In experiment 1, we examined sperm penetration rate at 12 hours of IVF with epididymal sperm. Total penetration rate among cauda epididymis and control was similar(mean${\pm}$standard error, cauda epididymis and control vs. $49.7{\pm}11.3$ and $54.4{\pm}12.8%$). In experiment 2, cleavage and blastocyst developmental rate were evaluated at day 2 and day 8 after IVF for 18 hours. Cleavage rate among cauda epididymis and control was similar(cauda epididymis and control vs. $81.2{\pm}3.4$ and $82.7{\pm}2.5%$). However, blastocyst developmental rate of cauda epididymis group was significantly higher than that of control group(cauda epididymis and control vs. $24.4{\pm}1.6$ and $12.2{\pm}2.8%$, p<0.05). In conclusion, cauda epididymal spermatozoa in Hanwoo bull has high embryo developmental competence and can be used as an alternative to ejaculated frozen sperm in vitro.

• Applied Chemistry for Engineering
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• v.29 no.1
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• pp.49-55
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• 2018

In this study, we investigated the cellular protective effects and mechanisms of nicotiflorin and its aglycone kaempferol isolated from Annona muricata. The protective effect of these components against $^1O_2$-induced cell damage was also studied by using L-ascorbic acid and (+)-${\alpha}$-tocopherol as controls. Kaempferol exhibited the most potent protective effect, followed by (+)-${\alpha}$-tocopherol and nicotiflorin. L-Ascorbic acid did not exhibit any cellular protective effects. To elucidate the mechanism underlying protective effects, the quenching rate constant of the singlet oxygen, free radical-scavenging activity, ROS-scavenging activity, and uptake ratio of the erythrocyte membrane were measured. The results showed that the cell membrane penetration is a key factor determining the cellular protective effect of kaempferol and its glycoside nicotiflorin. The result from L-ascorbic acid demonstrated that the cellular protective effect of a compound depends on its ability to penetrate the cell membrane and is independent of its antioxidant capacity. In addition, it is suggested that cellular protective effects of kaempferol and (+)-${\alpha}$-tocopherol depend not only on the cell permeability, but also on free radical- and ROS-scavenging activities. These results indicate that the cell permeability and free radical- and ROS- scavenging activities of antioxidants are major factors affecting the protection of cell membranes against the oxidative damage induced by photosensitization reaction.

• Journal of the Korean Wood Science and Technology
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• v.28 no.1
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• pp.42-47
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• 2000

This study was designed to investigate the effect of treatment variables on CCA treatment of Japanese red pine (Pinus densiflora), Japanese larch (Larix leptolepis), and ezo spruce (Picea jezoensis) round posts. Variables included were duration of initial vacuum (30, 45, or 60 minutes) and maximum pressure applied (8.5, 10.5, or 14.0 kg/$cm^2$), and maximum pressure was maintained until refusal point was reached. Regardless of wood species, extending the duration of initial vacuum more than 30 minutes did not affect treatability. Increasing pressure did not affect preservative penetration; however, preservative retention was affected by pressure levels, particularly at higher level (14.0 kg/$cm^2$). Preservative penetration depth of Japanese red pine met a minimum requirement specified by Notification of Korean Forestry Administration (No. 1999-8) for hazard class H5 of CCA-treated wood. Penetration of preservative in both Japanese larch and ezo spruce was not deep because of shallow sapwood thickness of these species, so pretreatment such as incising should be considered if these species are treated with preservatives. Although retention in Japanese red pine was not significantly increased even with 14.0 kg/$cm^2$, that of refractory Japanese larch and ezo spruce was significantly increased with the application of 14.0 kg/$cm^2$. Effect of treatment variables on refusal time was unclear; however, it is cleared that the refusal time was shortened with the increase in sapwood thickness.

• Journal of Life Science
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• v.24 no.1
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• pp.8-13
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• 2014

The moringa (Moringa oleifera Lam.) plant is used as food and as an anti-allergic agent. In this study, we studied the inhibitory effect of moringa root extract on the expression of PMA-induced matrix metalloproteinase-9 (MMP-9), which is the main factor implicated in the invasion and metastasis of cancer cells in MCF-7 cells. At first, various moringa extracts were examined in the MCF-7 cells. Both moringa root extract and leaf extracts inhibited PMA-induced MMP-9 activity, but the root extract suppressed PMA-induced MMP-9 activity to a greater extent than the leaf extract. The moringa root extract also inhibited PMA-induced MMP-9 protein expression and cell invasion. According to RT-PCR, the treatment of the MCF-7 cells with moringa root extract decreased levels of PMA-induced MMP-9 mRNA expression, but not the expression of TIMP-1 and -2, indicating that moringa root extract prevents the transcription of MMP-9 in response to PMA. In addition, moringa root extract specifically suppressed the phosphorylation of ERK/JNK, but not p38. We suggest that moringa root extract abolishes MMP-9 activity/expression through ERK/JNK. In conclusion, moringa root extract suppressed PMA-induced MMP-9 activity/expression by inhibiting the phosphorylation of ERK/JNK in MCF-7 cells. These results indicate that moringa root extract may be a potential antimetastatic and anti-invasive agent. Future clinical research is needed on the anticancer properties of moringa root extract.

• Journal of the Korea institute for structural maintenance and inspection
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• v.16 no.3
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• pp.23-30
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• 2012

For cracked concrete, it is obvious that cracks should be preferential channel for the penetration of aggressive substances such as chloride ions according to the previous researches. In order to extend the lifetime of cracked concrete, critical issues in the performance of the concrete is the risk of chloride-induced corrosion. Even though crack width can be reduced due to the high reinforcement ratio, the question is to which extend these cracks may jeopardize the durability of cracked concrete. If the size of crack is small, surface treatment system can be considered as one of the best options to extend the service life of concrete structures exposed to marine environment simply in terms of cost effectiveness versus durability performance. Thus, it should be decided to undertake an experimental study on the effect of surface coating system, which can be able to seal the concrete and the cracks to aggressive substances-induced corrosion in particular. In this study, it is excuted to examine the effect of surfaced treated systems on chloride penetration and carbonation through compressive stress induced cracks. Experimental results have showed conclusively that critical stress linked with deterioration, should be existed in compressive stress ratio 50 ~ 70% for chloride penetration and 70 ~ 80% for carbonation, respectively. When the critical stress is exceeded in concrete, a comparatively large deterioration was measured where the critical stress in concrete, the increase in the mass transportation is marginal in spite of the large increase in micro-cracks. As for the effect of surface coating system on crack-sealing, it can be seen conclusively that cracks can be healed.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.11 no.6
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• pp.239-245
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• 2001

$Al/Al_2O_3$composites were prepared from the reaction of mullite preforms and amorphous silica in aluminum melt at $1100^{\circ}C$ for 5 hrs. The chemical reaction between mullite preform and aluminum melt has formed the interconnected microstructure. The metal content of $Al/Al_2O_3$composite was controlled with the variable of the apparent porosity according to the sintering temperature of mullite preforms; $1600^{\circ}C$,$ 1625^{\circ}C$, $1650^{\circ}C$ and $1700^{\circ}C$, the mechanical properties of $Al/Al_2O_3$composite were investigated upon the content of Al. The mullite preform sintered above $1600^{\circ}C$ showed the chemical reaction with the penetrated Al melt, but the mullite sintered at $1600^{\circ}C$ didnt react with aluminum melt owing to the non-wetting of Al melt/mullite preform. The influences of penetration direction on the mechanical properties of composites were considered with the two different models of the perpendicular pattern and the parallel pattern to the direction of Al melt penetration. With the increase of Al metal penetration content, the fracture strength of $Al/Al_2O_3$composite decreased and the fracture toughness of composite increased. The microstructure of $Al/Al_2O_3$composite was determined by the direction of metal penetration, but the fracture strength and fracture toughness of composite didnt show the dependence on metal penetration direction.