• 건강소식
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• v.34 no.7
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• pp.12-13
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• 2010

잇몸병(치주질환)은 한국인이 가장 많이 앓는 질환 중 하나이다. 건강보험심사평가원의 진료비 통계지표(2009년 기준)에 따르면 치주질환진료가 감기 등의 호흡기 질환 다음으로 많다고 한다. 문제는 많은 사람들이 잇몸병에 시달리고 있지만 그 심각성을 크게 인식하지 못하고 있다는 점이다. 잇몸병이 합병증을 유발하는 질병의 뿌리인데도 말이다.

• The Monthly Diabetes
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• s.257
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• pp.32-33
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• 2011

건강한 치아는 오복(五福) 중의 하나로 여길 만큼 우리 몸에서 중요한 기능을 담당한다. 한 연구결과에 따르면 당뇨병환자가 치주질환이 있으면 헐당조절이 어려워질 뿐 아니라 뇌졸중, 심혈관질환 등 합병증이 조기에 발생할 수 있는 것으로 밝혀졌다. 당뇨병이 있으면 치주질환이 잘 생기는데 제대로 관리하지 않고 방치하면 전선질환까지 발생할 수 있는 것이다.

• Journal of Periodontal and Implant Science
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• v.34 no.3
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• pp.671-681
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• 2004

Genomic Project 이후로 다양한 질환에 있어서 유전적인 영향에 관한 연구가 진행되고 있다. 이 연구의 목적은 한국인 치주질환 환자에서 Fc ${\gamma}R$ 유전자의 유전자다형성과 치주질환 특성과의 관련성을 알아보는 것이다. 치주적으로 건강한 한국인 90명(대조군, 남자64명, 여자26명), 중도 만성 치주염환자 40명(severe chronic periodontitis patients; severe CP, 남자 24명, 여자 16명)을 대상으로 임상지수(치주낭 깊이, 입상부착소실, 치은지수, 치태지수, 탐침 후 출혈지수, 치조골소실)를 측정하였다. 또한 이들의 정맥혈에서 추출한 DNA를 PCR(Polymerase Chain Reaction)법, 전기영동법 등을 이용하여 Fc ${\gamma}RIIIa$ , Fc ${\gamma}RIIIb$의 대립유전자의 존재여부를 확인하였다. 이를 바탕으로 각 유전자의 다형성 및 Fc ${\gamma}R$ 복합유전자형 (Fc ${\gamma}R$ composite genotype)을 확인하여, 각 군 간을 비교하였다. 치주질환의 특성과 유전자 다형성과의 관련성을 알아보기 위하여 Fc ${\gamma}R$ 유전자에 대한 유전자다형성을 조사한 결과 다음과 같은 결과를 얻을 수 있었다. 1. Fc ${\gamma}RIIla$에 대한 유전자다형성 연구결과 대조군과 severe CP, AgP군 사이에서, severe CP와 AgP군 사이에서는 대립유전자분포가 서로 유의성 있는 차이를 나타내었지만(p<0.05), Fc ${\gamma}RIIlb$에서는 유의성 있는 차이를 보이지 않았다(p>0.05). 2. Fc ${\gamma}R$ 복합유전자형간의 비교에서 유의성 있는 차이를 발견할 수 없었다(p>0.05). 이와 같은 결과를 종합하여 볼 때 실험대상 한국인 치주염환자에서 Fc ${\gamma}R$ 유전자에 대한 다형성분석에서 Fc ${\gamma}RIIIa$ 대립유전자가 치주염에 대한 감수성과 관련되어 있다고 생각된다. 이 연구의 결과는 유전자의 차이가 치주질환의 감수성 판단의 자료로 활용할 수 있는 가능성을 보여주고 있다.

• 대한치주과학회:학술대회논문집
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• 1998.11a
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• pp.92-93
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• 1998

• Journal of the Korea Convergence Society
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• v.12 no.6
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• pp.49-56
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• 2021

This study aimed to identify the factors affecting the health-related quality of life in terms of periodontal disease by using the data from 8,035 respondents aged ≥40 years, excepting those with cancers having an serious impact on the quality of life, in the seventh Korea National Health and Nutrition Examination Survey (KNHANES) (2016-2018). The risk of quality of life deterioration was 1.32 times higher in the periodontal disease group than in the healthy periodontal group, those who were ≥50 years of age and had ≥2 comorbidities showed lower quality of life in the periodontal disease group. These results have confirmed that adults with periodontal disease get aware of the adverse quality of life though they have only a few chronic conditions and are expected to be useful as basic data necessary to develop health promotion programs that can help prevent periodontal disease and improve the health-related quality of life for adults.

• Journal of dental hygiene science
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• v.17 no.2
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• pp.160-167
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• 2017

The purpose of this systematic review was to investigate the association between periodontal disease and chronic kidney disease. A search of Embase, PubMed and The Cochrane Library databases was performed up to April 17, 2016. Article selection was based on cohort study design and the study subjects were patients with periodontal disease or severe periodontal disease. The final result was development of chronic kidney disease and kidney function decrease based on the estimated glomerular filtration rate values. The quantitative synthesis of the final selected articles was assessed using Review Manager statistical analysis software. A fixed-effects model meta-analysis was performed to estimate the degree of association between periodontal disease and chronic kidney disease. The search strategy identified 3,018 potentially eligible articles, of these, four studies were finally selected for meta-analysis, revealing that periodontal disease was significantly associated with the risk of developing chronic kidney disease (odds ratio, 1.65; 95% confidence interval, 1.44~1.90; p<0.001). In order to prevent the development of chronic kidney disease and kidney function decrease it is important to prevent periodontal disease, as well as minimizing the traditional risk factors known to reduce the quality of life of patients and increase disease burden.

• Journal of the Korea Convergence Society
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• v.12 no.1
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• pp.111-118
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• 2021

This study used raw data from the 2016-2018 National Health and Nutrition Survey to study the correlation between blood lipid and periodontal disease in Korean men and women, and selected the final 11,797 people as subjects of analysis. A stratified analysis of smoking and residential areas was conducted to see the link between blood lipid and periodontal disease in Korean men. In men, non-smokers had a significant correlation of 1.38(95% CI:1.09-1.76), and in men, the risk group had a odds ratio of 1.49(95% CI:1.16-1.91), and in smokers, the risk group had odds ratio of 1.76 (95% CI:1.39-2.23) shows that the warning group is significant in relation to the intersecting ratio 1.14(95% CI:1.16-1.70) and the risk group 1.60(95% CI:1.32-1.94) periodontal disease. In conclusion, men's blood lipids and periodontal diseases are associated with smoking or residential areas, and are especially intended to be used as basic data in developing health education programs related to systemic and periodontal diseases for men in urban areas. In developing education programs for men in urban areas in the future, we want to use them as basic data.

• Journal of Digital Convergence
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• v.15 no.9
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• pp.311-319
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• 2017

The purpose of this study was to examine the relationship between hours of sleep and periodontal diseases among adolescents based on the raw materials of the 5th third-year(2012) national health and nutrition examination survey. The subjects in this study were 593 selected teens who were at the western ages of 12 to 18. SPSS 18.0 for Windows was used to analyze general characteristics, health behavior, oral health care, mental health, and relationship of sleep duration to periodontal disease. As a result, the groups of adolescents who were older and whose household income was larger slept for less hours, and higher toothbrushing frequencies led to more hours of sleep. There were 2.28-fold more periodontal diseases in the group that got five or less hours of sleep than in the group that got eight or more hours of sleep. The above-mentioned findings of the study illustrated that insufficient sleep is linked to periodontal health in adolescence.

• 대한치주과학회:학술대회논문집
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• 2004.11a
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• pp.60-60
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• 2004

• Journal of dental hygiene science
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• v.18 no.4
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• pp.210-217
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• 2018

Periodontal disease is a chronic inflammatory disease that affects quality of life and nutrition. Several studies have demonstrated a link between periodontal disease and low bone density, and vitamin D is expected to have a beneficial effect on periodontal disease as well as on bone mineral density and anti-inflammatory effects. The purpose of this study was to identify the association between periodontal disease and vitamin D because the results are different in some studies and there is a lack of research in Korea. In this study, we conducted a multiple linear regression analysis of 8,783 subjects among 23,626 subjects who were older than 20 years of age, who had serum vitamin D levels and periodontal disease, who had three years of the National Health and Nutrition Survey that was conducted in Korea from 2012 to 2014. We examined the relationship between serum vitamin D levels and periodontal disease. Tooth loss and vitamin D levels were negatively correlated (${\beta}=-0.028$, p=0.008). In addition, the prevalence of periodontal disease was found to be higher in men younger than 50 years of age with lower vitamin D levels (Q1: 1.769 [1.125~2.782], Q2: 1.182 [0.743~1.881], Q3: 0.676 [0.400~1.881]; p=0.001). Low vitamin D levels and periodontal disease are common diseases in primary care. Vitamin D supplementation is expected to have favorable effect on periodontal disease and falls, osteoporosis, osteoarthritis, and cancer. Therefore, patients with periodontal disease may benefit from periodic vitamin D management to improve quality of life as well as to manage periodontal disease. In addition, as shown in this study, not only elderly individuals, but also men younger than 50 years of age are related to periodontal disease, so there should be interest in controlling the levels of vitamin D in adults.