• Title/Summary/Keyword: 추이

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Evaluation of the Biological Activity Affected by Extracting Solvents of Rosemary (Rosmarinus officinalis L.) (로즈마리(Rosmarinus officinalis L.) 극성별 용매 추출물의 생리활성 검증)

  • Li, Ke;Yang, Kyeong Hee;Guo, Lu;Cui, Zhengwei;Son, Beung Gu;Kang, Jum Soon;Lee, Yong Jae;Park, Young Hoon;Je, Beong Il;Choi, Young Whan
    • Journal of Life Science
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    • v.29 no.1
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    • pp.69-75
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    • 2019
  • Rosemary (Rosmarinus officinalis L.) is widely used as a food material. Although various physiological activities of rosemary have been reported, there have been no studies on the physiological activity of solvent extracts with different polarities. Rosemary extracts were obtained by extraction of dried powder using 0%, 25%, 50%, 70%, and 95% ethanol (EtOH) in distilled water, methanol, ethyl acetate, and hexane. As these ratios of EtOH are generally chosen by default and scarcely optimized, we investigated the impact of the composition of EtOH in distilled water on extract-related characteristics, such as DPPH free radical scavenging and ${\alpha}$-glucosidase inhibition, on the differentiation of 3T3-L1 adipocytes and inhibition of tyrosinase. Adipogenesis inhibition was highest at 70% EtOH. DPPH scavenging activity and inhibition of tyrosinase activity were reduced with 50% EtOH in water. However, inhibition of ${\alpha}$-glucosidase activity was higher in 50% EtOH in water. The best solvents in terms of DPPH scavenging activity, inhibition of tyrosinase and ${\alpha}$-glucosidase, and differentiation of adipocytes obtained with different concentrations of EtOH, although a lower similar activities were found with 50% ethanol. Considering the extraction solvents, a ratio of EtOH in water gives different content and constituents of compounds. These differences will give activities inhibition of adipogenesis, tyrosinase, ${\alpha}$-glucosidase activity, and DPPH scavenging activity.

Analysis of the Research Trends on Business Archives: Focusing on the Topic Modeling Analysis (기업 아카이브에 관한 연구 동향 분석: 토픽모델링 분석을 중심으로)

  • Kim, Hyosun
    • Journal of Korean Society of Archives and Records Management
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    • v.21 no.3
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    • pp.163-186
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    • 2021
  • The purpose of this study is to analyze research trends on overseas business archives, compare them with domestic and related prior studies, and present the direction of the development of domestic business archives research. For the research analysis, bibliography from 493 papers was collected using four academic databases: Web of Science, Scopus, LISA (ProQuest), LISS (EBSCOhost). Following data collection, data analysis was conducted and focused on the publication status of related papers, major journals, research forms, and researcher information. In addition, unique words were extracted through the data processing of English abstracts, and the frequency of the key words was identified. Through topic modeling, this study extracted seven topics from the entire literature group, analyzed the publication trends of the papers corresponding to each topic, and examined the topics and representative papers of that topic. The names for these topics were assigned as "access and usability of business records'," "information/evidence value of business records," "importance and operational strategy of business archives," "record management as a business heritage," "management of business records in digital environments," "preservation and disposal of business records," and "historical value of business records." Based on the prior research and analysis results, this study proposed implications for the development and expansion of future research on the domestic business archives.

Vegetation Structure and Distribution characteristics of Forest Community along Elevation on Mt. Hallasan (제주도 남동사면의 산림식생구조와 해발고별 산림군집 및 개체군 분포 특성)

  • Lee, Jeong Eun;Yun, Chung Weon
    • Journal of Korean Society of Forest Science
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    • v.110 no.2
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    • pp.141-154
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    • 2021
  • The change in vegetation structure along elevational gradients on the southeastern part of Mt. Hallasan was studied. Vegetation data were collected with 59 quadrates located from 16 to 1,565 m with 100 m intervals. Community types were classified using cluster analysis, and species composition and diversity were analyzed along elevational gradients. The vegetation was classified into seven, namely, type 1 Quercus serrata community, type 2 Carpinus tschonoskii community, type 3 Carpinus laxiflora community, type 4 Pinus densiflora community, type 5 Abies koreana community, type 6 Castanopsis sieboldii community, and type 7 Quercus acuta community. The species with a high importance value in tree layer in each elevational zone were C. sieboldii and Q. acuta at 100-600 m; C. laxiflora, Q. serrata, and C. tschonoskii at 700-800 m; P. densiflora at 1,100-1,200 m; and Abies koreana at 1,500-1,600 m. The species diversity indicated higher value at 700-800 m, 1,200-1,300 m and 1,400-1,500 m than at the other elevation.

The Patterns of Acquiring Anti-Mycobacterial Drug Resistance by Susceptible Strains of Mycobacterium tuberculosis (항결핵제 감수성 결핵에서의 내성 변화 추이)

  • Lee, Kyutaeg;Chong, Moo-Sang
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.2
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    • pp.137-142
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    • 2021
  • This study investigated the patterns of acquiring anti-mycobacterial resistance in individuals who were susceptible to all anti-mycobacterial drugs in their initial treatment. From 2010 to 2019, anti-mycobacterial drug susceptibility tests were conducted on patients who were referred to the Green Cross Laboratories. The test results of 594 anti-mycobacterial drug sensitivity tests were collected at 111 medical institutions. The first test results had 594 cases in which all anti-mycobacterial drugs were susceptible. Isoniazid (INH), rifampin (RIF), streptomycin (SM), and quinolone (QUI) showed the highest single-resistant conversion rates. Out of 56 patients, 17 patients (30.4%) showed a high conversion rate of resistance to both INH and RIF. The tracking period was analyzed from a minimum of 98 days to 1,862 days, and an average of 435.6 days for INH, and a minimum of 108 days to 1,673 days, with an average of 457.7 days for RIF. In the case of tuberculosis patients who are susceptible to all anti-mycobacterial drugs, it is considered that the conversion to resistant and multi-drug resistant tuberculosis (MDR-TB) must be confirmed through an anti-mycobacterial susceptibility test after 3 months. It is hoped that this study will help the national tuberculosis management project to improve public health.

Setting of Intensive Management Timing for Planting Trees in the Riverine Zone Based on Growth Analysis - Focusing on Planting of Pinus densiflora in the Nakdong River's Riverine Ecobelt - (생장량 분석을 기반으로 한 수변지역 식재수목의 집중관리시기 설정 연구 - 낙동강 수변생태벨트의 식재 소나무를 중심으로 -)

  • Lee, Soo-Dong;Kang, Hyun-Kyung;Song, Kwang-Seop
    • Korean Journal of Environment and Ecology
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    • v.35 no.2
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    • pp.126-134
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    • 2021
  • It is necessary to set a management period by analyzing growth trends for individual species because the time taken for planted trees to become established differs by species. The purpose of this study was to suggest an appropriate management period through the analysis of the annual growth of Pinus densiflora planted in the riverine eco belt. The average annual growth before planting was 0.6cm. The growth after planting showed an increase of 0.3cm in the 1st and 2nd year, 0.5cm in the 3rd and 4th year, and 0.7cm after the 5th year. Since P. densiflora was confirmed to go through poor growth stages in the 1st and 2nd year, a recovery stage in the 3rd and 4th year, and a normal growth stage in the 5th year, management should pay more attention to improve inappropriate environmental conditions until at least the 4th year, unlike the growth of hardwood. Since the period required for activation by species may vary, the management period of each species will need to be set through growth research.

Review of the Literature on Level of Biological Exposure and Trends in Possible and Probable Occupational Disease among Chromium Workers (크롬 직업병 유소견자와 요관찰자 추이 및 취급 근로자의 생물학적 노출수준 고찰)

  • Park, Sang-il;Kim, Nam-Soo;Hwangbo, Young;Kim, Hwa-Sung;Lee, Sung-Soo;Kim, Yong-Bae
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.31 no.3
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    • pp.213-225
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    • 2021
  • Objectives: This study identifies the trends in possible and probable occupational disease among chromium workers and reviews the literature on domestic and foreign chromium workers to review the industries, biological exposure levels, and major results. Methods: The results of the Ministry of Employment and Labor's special health-screening program for hazard agents among workers from 2009 to 2019 were used. Also, the industries, biological exposure levels, and major results on chromium workers were reviewed using PubMed and RISS. Results: The average annual proportion of both possible and probable occupational disease for chromium workers has recently increased. The average annual proportion of possible and probable occupational disease that can occur was high for both men and women in their 60s or older by age and 10 to 14 years by work duration. By industry, possible occupational disease showed high in manufacturing. In the literature review, many electroplating-related chromium-workers reported high levels of exposure to blood and urine chromium, as did dental technicians; tannery, tile factory or glass mill workers; cement workers; and sodium bichromate workers. Furthermore, a number of main findings in recent studies have reported that chromium exposure is related to genetic toxicity among workers. Conclusions: In this study, the average annual rate of both possible and probable occupational disease in domestic chromium workers is increasing, and a body of literature shows that chromium exposure is related to genetic toxicity and associated indicators among workers, which requires more systematic study.

Fandom-Persona Design based on Social Network Analysis (소셜 네트워크 분석을 이용한 팬덤 페르소나 디자인)

  • Sul, Sanghun;Seong, Kihun
    • Journal of Internet Computing and Services
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    • v.20 no.5
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    • pp.87-94
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    • 2019
  • In this paper, the method of analyzing the unformatted data of consumers accumulated on social networks in the era of the Fourth Industrial Revolution by utilizing data from the service design and social psychology aspects was proposed. First, the fandom phenomenon, which shows subjective and collective behavior in a space on a social network rather than physical space, was defined from a data service perspective. The fandom model has been transformed into a collective level of customer Persona that has been analyzed at a personal level in traditional service design, and social network analysis that analyzes consumers' big data has been presented as an efficient way to pattern and visually analyze it. Consumer data collected through social leasing were pre-processed by column based on correlation, stability, missing, and ID-ness. Based on the above data, the company's brand strategy was divided into active and passive interventions and the effect of this strategic attitude on the growth direction of the consumer's fandom community was analyzed. To this end, the fandom model of consumers was proposed by dividing it into four strategies that the brand strategy had: stand-alone, decentralized, integrated and centralized, and the fandom shape of consumers was proposed as a growth model analysis technique that analyzes changes over time.

Analysis of Change Transitions in Regional Types in Emergency Department Patient Flows of in Jeonlado (2014-2018) (전라지역 응급실 환자의 유출입 분석 및 지역유형 변화 추이)

  • Lee, Jae-Hyeon;Lee, Sung-Min;Kim, Seongjung;Oh, Mi-Ra
    • Journal of Convergence for Information Technology
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    • v.10 no.12
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    • pp.126-131
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    • 2020
  • This study analyzed the inflow and outflow patterns of emergency department patients, to identify changes in regional types in cities, counties, and districts in Jeonlado, Korea. Data of areas in Jeonlado for 2014 to 2018 were extracted from the National Emergency Department Information System. The extracted data includes the patients' and emergency medical institution addresses, which were used to calculate the relevance index (RI) and commitment index (CI). The calculated indices were classified into regional types by applying cluster analysis. A non-parametric method, Kruskal-Wallis test, was employed to examine the differences between years for RI and CI by regional types. The results of cluster analysis using the relevance and commitment indices revealed three regional types. Regions in cluster 1 were classified as outflow type, in cluster 2 as inflow type, and in cluster 3 as self-sufficient. RI and CI were calculated for each cluster or regional type. There were no significant differences between years in cluster 2 (inflow type) and cluster 3 (self-sufficient type). In cluster 1 (outflow type), there were no significant differences in CI between the years; however, there were significant differences in RI between 2014 and 2017, and 2014 and 2018. It is difficult to see that the emergency medical environment has improved due to the increased concentration of emergency medical care.

Changes in Hydrological Characteristics of a Forested Watershed of Mt. Palgong (팔공산 산림소유역의 유출 특성 변화)

  • Jung, Yu-Gyeong;Lee, Ki-Hwan;Choi, Hyung-Tae;Lee, Heon-Ho
    • Journal of Korean Society of Forest Science
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    • v.109 no.4
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    • pp.429-437
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    • 2020
  • In this study we quantified the long-term change in discharge against precipitation in a forested watershed and investigated how the growth of forest trees influences these changes. We found a proportional relationship between precipitation and discharge for each year, and discharge decreased gradually with time. Precipitation and discharge were highest in July and August, and the changes in precipitation, discharge, and runoff rate did not always coincide, given that high runoff rate was shown in August and September. The monthly coefficient of variation (CV) for discharge was larger than that for precipitation, and the deviation between precipitation and discharge increased gradually. From 2011 to 2017, the gradient of the trend line for the change of total discharge and direct runoff against precipitation decreased, whereas the gradient of the base flow increased in this same time period. A possible explanation is that the water holding capacity of soil deposits increased as the forest soil of the Palgong Mountain watershed developed and the increase of base flow rose with groundwater level together with that of outflow quantity. The coefficient of flood recession was lower in the period 2011 to 2017 than in 2003 to 2010; thus, the reduction of discharge was mitigated and remained steady as time progressed. We conclude from these results that the discharge of surface runoff decreased as tree growth and base flow increased; however, the water yield function of the forest increased gradually.

Study on the Research Trend of Overseas Elderly Occupational Therapy Using Text Mining (텍스트마이닝을 활용한 국외 노인작업치료의 연구동향 분석)

  • Kim, Ah-Ram;Lee, Tae kwon;Jeong, In Jae;Park, Hae Yean
    • Therapeutic Science for Rehabilitation
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    • v.10 no.1
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    • pp.7-17
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    • 2021
  • Objective : The purpose of this study was to quantitatively analyze the quantitative changes in, and the status of, overseas occupational therapy using text mining. Methods : Using PubMed, research papers on Elderly, Health and Occupational therapy published between 2009 and 2019 were selected for analysis, Abstracts of the selected papers were analyzed. The number of annual papers, the key words, the key words by year, and the relationship between the words were analyzed. Results : The number of papers published from 2009 to 2019 was 9,941, there was a gradual increase from 2009 to the highest in 2017 or 2018, followed by a decreasing trend in 2019. Within the last five years, the most frequent words were Care, Group, Intervention, Pain, Treatment, and Work. There was a strong relationship between the words based on the average frequency over the last 11 years, function, health, event, and partition. Conclusion : This study is meaningful because it applied a new research method called text mining to the empirical and systematic analysis of trends in occupational therapy and presented macroscopic and comprehensive results. The findings are expected to help establish new research directions at clinical and research sites for occupational therapy related to older adults.