• Journal of Radiation Industry
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• v.7 no.1
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• pp.75-80
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• 2013

This study was designed to elucidate the effect of fermented blackberry drinks (BD) on alcohol metabolism and hangover in alcohol-treated rats. We showed that the administration of BD increased the activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in alcohol-treated rats. Moreover, the administration of BD reduced the serum alcohol and acetaldehyde concentrations in alcohol-treated rats. Furthermore, the administration of BD attenuated the levels of serum aspartate aminotransferase and alanine aminotransferase in alcohol-treated rats. Taken together, these results suggest that BD plays an important role in alcohol metabolism and liver function by reducing blood alcohol and acetaldehyde through the activation of ADH and ALDH in alcohol-treated rats and could be used as a functional anti-hangover drinks.

• Journal of Radiation Industry
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• v.8 no.1
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• pp.7-10
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• 2014

This study was designed to evaluate the protective effect of silkworm hemolymph against ${\gamma}-irradiation$ induced damage in the liver of mice. Female Balb/C mice (6 weeks old) were exposed to ${\gamma}-irradiation$ (6 Gy) and administered orally to silkworm hemolymph ($5ml\;kg^{-1}$ BW) for 7 days post-irradiation. The body weight, spleen index, plasma aspartate transaminase (AST), plasma alanine transaminase (ALT), and liver malondialdehyde (MDA) levels were determined. Compared with irradiated control mice, the activity of plasma AST and the level of MDA were significantly decreased in mice treated silkworm hemolymph. These results show that silkworm hemolymph is found to have a protective effect against ${\gamma}-irradiation$ induced damage in mice.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.3
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• pp.76-82
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• 2021

At present, with the development of precision instruments, high dimensional accuracy of workpieces must be ensured. In particular, for the aluminum alloys used in automobiles, the surface roughness of the workpiece is extremely important. The dimensional accuracy and surface roughness of the workpiece is considerably affected by the rotational accuracy of the rotor. Therefore, to enhance the rotational accuracy, various variables such as those related to the components such as bearings, motors, and end mills, rotational speeds, and vibrations must be considered. In this study, the difference in the quality of the workpieces was compared considering the weight imbalance and rotational speed as variables.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.9 no.1
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• pp.153-164
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• 2014

This study is to investigate the effects of intangible assets such as research & development, education & training and advertisement on firm values of high-technology firms and low-technology firms listed in the KOSDAQ market, and to analyze the value-relativeness between the audit quality of companies and the expenditure of intangible assets. The substitute measurement of firm values is Tobin's Q model. The sample period for positive analysis is from 2003 to 2008, and the samples, excepting for financial business, are manufacturing companies of closing accounts corporate on December, based on companies of KOSDAQ that are listed in security. Finally, data from about 305 companies are used in this analysis. Followings are the results of the analysis. First, research & development, education & training of high-technology firms have an effect on firm values, and education & training of low-technology have an effect on firm values. Second, we find that audit quality(BIG4) increases the value relevance of R&D expenditures of high-technology firms and audit quality(BIG4) increases the value relevance of education & training expenditures of low-technology firms. This paper is meaningful in that it verified the value-relativeness of cost of intangible assets compared with high-technology firms to low-technology firms.

• Journal of Biomedical Engineering Research
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• v.42 no.6
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• pp.259-267
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• 2021

Recently, the market for personal health care and medical devices based on Bluetooth Low Energy(BLE) has grown rapidly. BLE is being used in various medical data communication devices based on low power consumption and universal compatibility. However, since data errors occurring in the transmission of medical data can lead to medical accidents, it is necessary to analyze the causes of errors and study methods to reduce data error. In this paper, the minimum communication speed to be used in medical devices was set to at least 800 byte/sec based on the wireless electrocardiography regulations of the Ministry of Food and Drug Safety. And the data loss rate was tested when data was transmitted at a speed higher than 800 byte/sec. The factors that cause communication data error were classified, and the relationship between each factor and the data error rate was analyzed through experiments. When there were two or more activated peripherals connected to the central, data error occurred due to channel hopping and bottleneck, and the data error rate increased in proportion to the communication distance and the number of activated peripherals. Through this experiment, when the BLE is used in a medical device that intermittently transmits biosignal data, the risk of a medical accident is predicted to be low if the number of peripherals is 3 or less. But, it was determined that BLE would not be suitable for the development of a biosignal measuring device that must be continuously transmitted in real time, such as an electrocardiogram.

• Venture DIGEST
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• s.67
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• pp.16-18
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• 2005

최근 기술유출이 갈수록 빈발하고 있어 반도체, 휴대폰 등 첨단 신기술개발 핵심 주체인 벤처기업의 보안체계에 비상이 걸렸다. 기술유출 방법 역시 갈수록 첨단∙전문화되고 있어 이를 방지하는 데 사운을 걸어야할 지경이다. 기술유출은 비단 해당 기업의 피해로 국한되는 것이 아니다. 기술유출을 위한 국제 스파이 조직이 활개를 치고 있는 요즘 기술유출은 곧 국부유출로 이어진다. 이에 본지는 국부유출을 막기 위해 각고의 노력을 기울이고 있는 서울중앙지검 첨단범죄수사부 이득홍 부장검사를 만나 기술유출의 심각성과 대응책 등 기술유출 전반에 관한 이야기를 들어보았다.

• Journal of the Korean Professional Engineers Association
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• v.30 no.6
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• pp.40-58
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• 1997

교통정보의 지능화처리에 따라 교통 체계에서의 변화가 전개되고 있다. 특히 전세계적으로 지능화된 첨단 교통 시스템으로 ITS(Intelligent Transportation System)가 등장하여 표준화된 첨단교통 정보의 체계가 진척되고 있다. 본고에서는 ITS 분야 중에서 첨단 여행자 정보 분야인 ATIS(Advanced Traveller Information Service)에 대하여 주행 및 여행자 정보 서비스의 기능 규격을 정리하고 이의 실현 방안으로 검토되고 있는 다양한 무선 데이터 통신망의 적용을 위한 기술을 검토하고자 한다.

• 전기의세계
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• v.41 no.12
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• pp.38-42
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• 1992

1980년대 후반부터 국내 제조업의 생산시스템을 획기적으로 개선시켜야 할 필요성이 세가지 측면에서 보다 구체적으로 나타나기 시작하였다. 1. 국제경쟁력을 결정하는 주요 요인이 종래의 부존자원과 자본 중심에서 자동화.정보화를 통한 지식, 정보, 창의력에 의한 첨단기술 중심으로 점차 변화되고 있고 2. 노동력 부족상태가 심화됨에 따라 1인당 부가가치 생산액이 크게 증대되어야 한다는 것이고 3. 기계, 전자, 자동차 등과 같은 첨단 산업이 제조업에서 차지하는 비중이 급증할 것으로 예견됨에 따라 산업 구조의 질적 고도화를 뒷받침할 기반정립이 시급히 요구되고 있다는 것이다. 이러한 측면들을 종합하여 볼때, 첨단생산시스템의 개발은 매우 시의절적하고도 중요한 일이라 할 것이다.

• Journal of Biomedical Engineering Research
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• v.40 no.2
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• pp.39-47
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• 2019

Ultrasound sonication along with microbubble (MB) could enhance drug delivery to promote the absorption of anticancer drugs into cancers in a noninvasive and targeted manners. In this study, we verify the acute drug delivery enhancement (within an hour) of two representative focused ultrasound driven drug delivery enhancement methods (MB and Doxorubicin-coated Nanoparticle complex (MB-NP) based). Experiments were conducted using in vivo mouse model with MDA-MB-231 breast cancer cell line. Ultrasound generated by single-element 1 MHz focused ultrasound transducer was delivered in pulsed sonication consisted of 0.125 msec bursts at a pulse repetition frequency of 2 Hz for 20 seconds without a significant increase in local temperature (less than $0.1^{\circ}C$) or hemorrhage. Doxorubicin concentrations in tumors were improved by 1.97 times in the case of MB-NP, and 1.98 times by using Doxorubicin and MB separately. These results indicate anticancer drug delivery based on MB and MB-NP can significantly improve the effect of anticancer drugs delivered to tumors in a short time period by using low-intensity focused ultrasound.

• The monthly packaging world
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• s.97
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• pp.140-143
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• 2001