• Food Science and Preservation
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• v.16 no.1
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• pp.115-121
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• 2009

We prepared five different kinds of herb mixtures prescribed for hypoglycemic effect. And the physicochemical properties of their water extracts were assessed to identify functional materials. Yields were in the range $19.52{\sim}29.79%$. Total phenolics and flavonoid contents were $349.24{\sim}1,752.21\;mg%$ and $163.06{\sim}1,118.47\;mg%$, respectively, and herb mixtures No. 2, 3 and 5 showed particularly high levels greater than 1,000 mg%. Electron-donating ability was best in herb mixtures showing high levels of total phenolics and flavonoids. Nitrite-scavenging abilities were more than 70% in herb mixtures No. 2 and 5, and decreased as pH increased. Herb mixture extracts strongly inhibited differentiation of 3T3-L1 fibroblasts, with potencies ranked in the herb mixture order 5, 1, 4, 3, and 2. The five different kinds of herb mixtures prescribed for their hypoglycemic effects may be useful as functional food materials.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.2
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• pp.155-161
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• 2021

This study was attempted to investigate natural materials with antimicrobial activity and to apply as natural preservatives in cosmetics. The disc diffusion method was used to search for nine species of natural antibacterial material for three species of skin pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa) and Candida albicans. As a result of measuring the size of inhibition zone, Rhus Semialata gall (Gallnut) extract, Oak vinegar, and ε-polylysine were showed strongest antibacterial activities (> 10 mm). The Minimum Bactericidal Concentration (MBC) of gallnut and oak vinegar ranged from 10 to 20 mg/mL and from 20 to 40 mg/mL against five human skin pathogens. The MBC of ε-polylysine ranged from 0.5 to 2 mg/mL in fungus. The synergic effect of gallnut extract/oak vinegar mixture and gallnut extract/ε-polylysine mixture were evaluated by checkerboard test. Compared to when used alone, the MBC of gallnut extract/oak vinegar mixture were at 4 times lower concentration against E. coli, C. albicans, and A. brasiliensis. Also Furthermore, the MBC of gallnut extract/ε-polylysine mixture were at 4 times lower concentration against C. albicans and A. brasiliensis. It was confirmed that the combination of gallnut extract with oak vinegar or ε-polylysine resulted in synergistic antibacterial effect against three human skin pathogens. Thus, it is expected that gallnut extract and natural product mixture can not only demonstrate antibacterial synergies, but also be applied in cosmetics as a natural preservative system with a wide antibacterial spectrum.

• Elastomers and Composites
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• v.3 no.1
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• pp.62-74
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• 1968

천연(天然)고무 및 합성(合成) 고(高) cis 1 : 4 polyisoprene, 대표적(代表的)으로 'Natsyn 400'의 가공(加工), 배합(配合) 또는 가황체(加黃體)의 성질(性質)들의 차이점(差異點)들에 대(對)하여 설명(說明)하였다. 합성중합체(合成重合體)는 미리 소연(素鍊)함이 없이 충전제(充塡劑)를 첨가(添加)함으로서 가공(加工)이 용역(容易)하였으며 CV형(形) 천연(天然)고무에 있어서도 이점(利點)이 나타났다. 천연(天然)고무 배합물(配合物)은 점착성(粘着性)이 좋으며, 특(特)히 미가황물(未加黃物)의 강도(强度)가 현저(顯著)하게 우수(優秀)하다. 가황과정(加黃過程) 및 몇몇가황체(加黃體)의 성질(性質)에 있어서의 차이(差異)는 비(非)고무질(質)을 함유(含有)하지 않는 Natsyn으로 나타난다. 기타(其他)의 가황체성질(加黃體性質)의 차이(差異)는 천연(天然)고무에 있어서 그 가황체(加黃體)가 인장시(引張時)에 결정(結晶)하는 경향(傾向)을 크게 나타내고 있고 특(特)히 고온(高溫)에서 이들 차이(差異)가 현저(顯著)하다.

• Proceedings of the Korean Fiber Society Conference
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• 2003.04a
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• pp.431-431
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• 2003

건강과 환경에 대한 관심이 고조되면서 이에 따른 생활의 양상도 다양하게 변화되고 있다. 보다 쾌적한 생활 환경을 추구하려는 노력으로 최근 쾌적 섬유의 제조 및 가공에 대한 많은 연구결과가 발표되고 있는 실정이다. 그러나, 합성 항균제를 사용한 항균 가공 직물의 경우 안전성 및 환경친화성에 대한 소비자의 기피현상이 나타나고 있으며, 천연물에 대한 관심이 높아지고 있다. 최근에는 키토산을 비롯하여 양파, 쑥, 계피정유, 및 기타 한약재의 추출물을 사용하여 항균성을 확보하고자하는 연구가 계속되고 있다. (중략)

• Proceedings of the Korean Society of Applied Pharmacology
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• 2001.11a
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• pp.87-87
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• 2001

최근 치의학 영역에서 사용되는 천연물 특히 생약제에 대한 연구가 활발히 진행되고 있다. Scutellariae Radix, Centella asiatica 등이 치주인대세포의 활성을 증가시키고 홍삼사포닌이 배양한 치주인대세포의 성장, 분화에 관계된다는 보고 등이 이에 해당된다. 본 연구에서는 홍화자 메탄을 추출물과 키토산의 치주인대 세포의 증식, 분화, 석회물 결정 생성 촉진작용을 검토하여 치주경조직 재생 약물로서의 사용여부를 보고자 하였다. 치주인대 세포는 교정치료목적으로 경희의료원에 내원한 환자의 제1 소구치를 발거하고 치근시작점에서 중앙으로 1/3되는 지점에서 치주인대 조직을 절취하여 1차 배양하였다. 실험에는 계대배양하여 5-7 세대의 세포를 사용하였다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.12
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• pp.1571-1577
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• 2007

The herb mixtures that are known to lower blood pressure were selected through oriental medical books and prescriptions and the physicochemical properties of their water extracts were analyzed to examine the possibility as functional food materials. The total yield of 28 water extracts was in the range of $5.33{\sim}36.71%$. Total phenolics and flavonoid content were $204.89{\sim}2543.29mg%\;and\;59.79{\sim}1430.55mg%$, respectively, and especially No. 2, 5, 9, 17, 18, 20, 22, and 26 showed high rates of above 800 mg%. Electron donating ability (EDA) was $7.81{\sim}98.18%$, and the samples that showed high values in EDA were similar to the samples with high values in total phenolics and flavonoid content. Phenolics and flavonoid compounds of the herbs are considered to perform a major role in antioxidation. Nitrite scavenging ability reached the highest at pH 1.2 ($11.70{\sim}96.47%$) and the lowest at pH 6.0 (below 12.77%), which indicates that nitrite scavenging ability decreases when pH increases.

• Journal of Life Science
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• v.30 no.2
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• pp.202-210
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• 2020

As the elderly population increases, it is becoming important to prevent and treat muscle loss caused by aging or disease. Steroidal androgen in the protein assimilation steroid (AAS) system is mainly used to induce muscle improvement, but it is well known that long-term or excessive doses of AAS result in various side effects, although they are prescribed for various muscle and weight loss treatments. Research is therefore underway to explore natural substances that promote muscle renewal with relatively few side effects. However, despite many studies on the improvement of skeletal muscle and the reduction of muscle disease using natural products, there is still a lack of significant clinical results and mechanism studies. The promotion of muscle regeneration through treatment with natural substances typically involves three mechanisms: positive control of the muscle modulating factor (MRF), activation of the protein synthesis mechanism, and inhibition of the protein breakdown mechanism. A study of plant extracts that are known to have muscle neoplasmic stimulation effects, such as black ginseng, plum, and nutmeg, as well as single substances derived from natural products, such as creatine, catechin, and several fatty acids, is therefore described. We also summarize the mechanisms that have been identified so far through which each of these extracts or single materials facilitates muscle regeneration and the signaling pathways that they mediate.

• Life and Agrochemicals
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• v.27 no.7 s.220
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• pp.42-43
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• 2006

• Food Industry And Nutrition
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• v.6 no.1
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• pp.46-53
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• 2001

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.58-58
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• 2005