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The Effects of Ascorbic Acid on Full-thickness Skin Wound Healing in Dogs (개에서 Ascorbic Acid가 피부 결손창 치유에 미치는 영향)

  • Kim Jung Hun;Cheong Jongtae;Park Hyun Jeong;Kim Jae Hoon;Lee Kyoung-kap;Son Won-geun;Kang Tae-young;Yun Young-min;Hwang Kyu-kye;Park Jong-Cook;Lee Joo Myoung
    • Journal of Veterinary Clinics
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    • v.22 no.4
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    • pp.342-347
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    • 2005
  • This study was designed to assess the healing effects of ascorbic acid on full-thickness skin wound in dogs. Four $2.5\pm2.5cm$ full-thickness skin wounds were created bilaterally on the dorsolateral aspect in each of 5 dogs. The ten wounds were treated with ascorbic acid solution in the experimental group, and the ten wounds were treated with $0.9\%$ saline in the control group. The wound healing area was measured every other day for 3 weeks after the wounding. Statistical analysis was conducted with the paired t-test. On the $1^{st},\;3^{rd},\;5^{th},\; 7^{th},\;9^{th},\;11^{th},\;13^{th},\;15^{th},\;17^{th},\;19^{th},\;21^{st}days$, the wound healing rates were $12.6\pm9.6\%,\;9.5\pm9.8\%,\;18.9\pm9.0\%,\;39.2\pm5.4\%,\;62.2\pm4.6\%,\;86.9\pm1.9\%,\;92.9\pm1.8\%,\;96.6\pm1.6\%,\;99.1\pm0.5\%,\;99.8\pm0.2\%,\;99.9\pm0.1\%$ in the experimental group, and $9.1\pm6.0\%,\;9.2\pm6.0\%,\;12.2\pm5.0\%,\;41.3 \pm6.3\%,\;54.2\pm9.2\%,\;81.0\pm2.6\%,\;85.7\pm2.8\%,\;92.3\pm1.5\%,\;96.1\pm0.7\%,\;98.0\pm0.8\%,\;99.5\pm0.2\%$ in the control group On the $15^{th}$ day, the wound closed above $99\%$ in 2 dogs of the experimental group. On the $17^{th}$ day, the wound closed above $99\%$ in 3 dogs of the experimental group. On the $19^{th}$ day, the wound closed above $99\%$ in 5 dogs of the experimental group, and 2 dogs of the control group. On the $21^{st}$ day, the wound closed above $99\%$ in 5 dogs of the experimental group, and 4 dogs of the control group. The wound healing rate of the experimental group was $2\~4$ days faster than that of the control group. The tensile strength was $4,169\pm1,107g/cm^2$ in the experimental group, and $2,438\pm637g/cm^2$ in the countrol group on the$21^{st}$ day after wounding. Tensile strength was significantly higher in the experimental group than in the control group (p<0.05). The histopathological findings of the experimental group were similar to those of the control group on the $1^{st},\;3^{rd}\;and\;5^{th}$days. Inflammation and revascularization of the experimental group were similar to those of the control group on the $9^{th},\;13^{th}\;and\;21^{st}$days. The formation of collagen and reepithelialization were more developed the experimental group than in the control group on the $9^{th},\;13^{th}\;and\;21^{st}$days. Significantly higher wound healing rate, tensile strength and better histopathological findings were observed in the experimental group than in the control group. These results suggest that the topical application of ascorbic acid on full-thickness skin wounds can promote wound healing process.

The Effect of Private Security Perception of Organization Justice on Organization Member Behavior (민간경비원의 조직공정성 지각이 조직시민행동에 미치는 영향)

  • Kim, Myung-Hyun;Yu, Hyung-Chang
    • Korean Security Journal
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    • no.14
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    • pp.69-87
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    • 2007
  • Study results on the perception of organization justice and organization member behavior of private security are as below. Primarily, organization justice showed variation according to socio-demographic characteristics which include age, the period the person has stayed in the current workplace, total period of working and monthly income. As for age, in aspect of the perception of distribution justice, the 36 or older age group prevailed, and the 31 to 35 age group prevailed in the perception of procedure justice. So, perception of organization justice increased accordingly with age. According to the period the person has stayed in the current workplace category, showed high levels in the perception of distribution justice and perception of procedure justice in the $3\;{\sim}\;5$ years group. As for total period of working, both perception of distribution justice and the perception of procedure justice proved greatest in the 5 years or more group and according to monthly income, the KRW 1800,000 or more group showed high levels of perception of distribution justice and the perception of procedure justice. Secondly, organization member behavior showed variation according to sociodemographic characteristics. In organization member behavior, loyal behavior increased along with age and inter-personal relationship behavior and altruistic behavior prevailed in the age group 31-35 According to period the person has worked at the current workplace and in case of total period of working, loyal behavior, inter-personal relationship behavior and altruistic behavior proved to be high. As for monthly income, an increase in monthly income resulted in a high figure in loyal behavior, inter-personal relationship behavior and altruistic behavior. Thirdly, after regression analysis of the relationship of the perception of organization justice and organization member behavior, perception of procedure justice was analyzed to have relatively high influence. Therefore, the hypothesis presented in this study was all chosen after the regression analysis results. This shows that the enhancement of organization member behavior can be improved. by enhancing the perception of organization justice. Thus, it can be concluded that if a private guard recognizes his justice, organization member behavior can be enhanced.

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Manufacturing and Feed Value Evaluation of Wood-Based Roughage Using Lumber from Thinning of Oak and Pitch Pine (참나무류와 리기다소나무 간벌재를 이용한 목질 조사료 제조 및 사료가치 평가)

  • Kim, Seok Ju;Lee, Sung-Suk;Baek, Youl Chang;Kim, Yong Sik;Park, Mi-Jin;Ahn, Byeong Jun;Cho, Sung-Taig;Choi, Don-Ha
    • Journal of the Korean Wood Science and Technology
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    • v.43 no.6
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    • pp.851-860
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    • 2015
  • The objective of this study was to manufacture the wood based roughage using lumber from thinning of oak and pitch pine (Pinus rigida). And the study also aimed to investigate a feed value evaluation of wood based roughages. To investigate the optimization condition of steam-digestion treatment for roughage, the wood chips of oak and pitch pine were steam-digestion treated at $160^{\circ}C$ under pressure 6 atm depending on treatment times (60 min, 90 min and 120 min) followed by the content of essential oils analyzed. The essential oil content of steam-digestion treated roughages for 90 min and 120 min were under 0.1 mL/kg. The evaluation of feed value was carried out from steam-digestion treated roughages for 90 min through feed chemical composition analysis, NRC (National research Council) modeling, ruminal degradability analysis and relative economic value analysis. The feed chemical compositions including DM (dry mater), CP (crude protein), EE (ether extract), NDF (neutral detergent fiber), ADF (acid detergent fiber), ADL (acid detergent lignin), NFC (nonfiber carbohydrate) in oak roughage were 95.4, 1.36, 3.11, 90.05, 83.85, 17.33, 6.50%, respectively, and in pitch pine roughage were 94.37, 1.33, 5.48, 87.89, 86.88, 30.56, 6.32%, respectively. Both roughages showed low level of protein and very high level of NDF. The TDN (total digestible nutrient) levels using NRC (2001) model in oak and pitch pine roughages were 40.55, 31.22%, respectively. The ruminal in situ dry matter degradability was higher in oak roughage (23.84%) than in pitch pine roughage (10.02%). The economic values of oak and pitch pine rough-ages were 235, and 210 \, respectively.

Video-Assisted Thoracic Surgery Lobectomy for Non-Small Cell Lung Cancer: Experience of 133 Cases (폐암에서의 흉강경 폐엽절제술 치험 133예)

  • Kim, Hyeong-Ryul;Cho, Jeong-Su;Jang, Hee-Jin;Lee, Sang-Cheol;Choi, Eun-Suk;Jheon, Sang-Hoon;Sung, Soak-Whan
    • Journal of Chest Surgery
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    • v.42 no.5
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    • pp.615-623
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    • 2009
  • Background: We evaluated the feasibility and the efficacy of Video-Assisted Thoracic Surgery (VATS) lobectomy for treating patients with non-small cell lung cancer (NSCLC) and we compared the outcomes of VATS lobectomy with those of open lobectomy. Material and Method: From 2003 to March 2008, 133 NSCLC patients underwent VATS lobectomy. The patients were selected on the basis of having clinical stage I disease on the chest CT and PET scan. The outcomes of 202 patients who underwent open lobectomy (OL group) for clinical stage I NSCLC were evaluated to compare their results with those of the patients who underwent VATS lobectomy (the VL group). Result: The number of females and the number of patients with adenocarcinoma and stage IA disease were greater in VL group (p<0.05). There was no operative mortality or major complications in the VL group. Conversion to thoracotomy was needed in 8 cases (6%), which was mostly due to bleeding. The chest tube indwelling time and the length of the postoperative hospital stay were significantly shorter in the VL group (p<0.001). The number of dissected lymph nodes and the size of tumor were significantly smaller in the VL group (p<0.001). For the pathologic stage I patients, there was no significant difference in the three-year survival rates between the two groups (p=0.15). Conclusion: VATS lobectomy is a safe procedure with low operative mortality and morbidity. VATS lobectomy is feasible for early stage NSCLC and it provides outcomes that are comparable to those for open lobectomy. Further long-term data are needed.

Clinical Analysis of Video Assisted Thoracic Surgery for the Treatment of Thoracic Empyema (비디오 흉강경을 이용한 농흉수술의 임상분석)

  • Oh, Sang-Gi;Song, Sang-Yun;Yun, Chi-Hyeong;Na, Kook-Ju;Kong, Kang-Eun;Park, Song-Ran;Kim, Sang-Hyung
    • Journal of Chest Surgery
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    • v.43 no.2
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    • pp.139-143
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    • 2010
  • Background: Thoracic empyema remains a serious problem despite the availability of modern diagnostic methods and appropriate antibiotics. The condition presents in many different forms and stages that require different therapeutic options. Video-assisted thoracic surgery (VATS) has become increasingly popular for use in the treatment of empyema. Material and Method: From January 2005 to May 2009, VATS was performed in 36 patients with pleural empyema and for whom chest-tube drainage and antibiotic therapy had failed or the CT scan showed multiseptate disease. The perioperative clinical factors were analyzed for all the study patients. Result: All the patients underwent VATS, but it was necessary to convert to thoracotomy in one patient. The mean operation time was $90{\pm}38.5\;min$. For the operative evaluation, 11 patients were compatible with ATS stage III. The duration of chesttube insertion was $11.9{\pm}5.8$ (3~24) days. One patient did not improve and therefore this patient underwent additional open drainage. At discharge, costophrenic angle blunting was observed in 22 patients, pleural thickening was noted in 20 patients, both were noted in 17 patients and neither was noted in 11 patients. However, at follow-up, each of these changes was observed in 9, 7, 4 and 24 patients, respectively. All except one patient showed radiographic improvement. Conclusion: VATS is suitable for the treatment of early and fibrinopurulent thoracic empyema, and even in selected patients with stage III disease.

Empirical Analysis of University Patenting in Korea (특허자료를 이용한 우리나라 대학 연구의 특성 분석)

  • Suh, Joonghae
    • KDI Journal of Economic Policy
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    • v.32 no.4
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    • pp.115-151
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    • 2010
  • Recently Korean universities show very rapid increases in both patents and R&D (research and development) expenditures. During the period from 1970 to 2008, university R&D spending has on the average increased 15.3% annually. Along with steady increases in R&D spending, university's research outputs have also continuously increased. In 1990 Korea as a total published 1,613 SCI-level scientific papers and Korean universities applied 27 patents to Korea patent office. In 2008, Korea published more that 35,000 SCI papers and Korean universities applied about 7,300 patents. The growth of scientific articles had begun from the early 1990s whereas the growth of patent has ignited entering the 2000s. The paper tried to investigate university research through the window of patent. Patents lie between invention and innovation and represent the potential value of invention which will be realized at the marketplace. Since Korean patents do not contain citation information, the paper used US patents-NBER patent database-as the main data. The key empirical question is whether Korean university patents granted from USPTO are characteristically different from other Korean patents granted from USPTO. Previous studies on US and Europe show that corporate patents are more stylized in appropriablity of invention, whereas university patents basicness. In case of Korea, the paper confirmed the appropriability characteristic of corporate patents; but the Korean unversity patents are not distinguishable in terms of basicness. The paper estimated the citation frequency function-an empirical model which was firstly developed by Caballero and Jaffe (1993) and later articulated by Jaffe and Trajtenberg (1996, 2002). The model is specified mainly composed of two interacting parts-diffusion effect and obsolescence effect of new ideas or innovations. Estimation results show that differences in forward citations between university and corporate patents are not statistically significant, after controlling self-citation. Since forward citations represent the quality of patents, this estimation result implies that there are no statistically significant quality differences between university and corporate patents. Prior research results, based on the same model of citation frequency function, about US and some European cases show that, in terms of forward citations, university patents are generally superior to corporate patents -for the case of US- or, the former not inferior to the latter-for the case of most of Europe. It is argued that some important and significant policy changes caused the rapid rise of university patents in Korea. Policy changes include the revision of technology transfer act allowing the ownership of publicly-funded research results to researchers and the changes in faculty/professor evaluation which gives more credit to the number of patents. These policy changes have triggered the rapid growth of the number of university patents. The results of the empirical analysis in this paper indicated that Korea now needs to make further efforts to enhance the quality of university patents, not just to produce more numbers of patents.

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Study on the Geoelectrical Structure of the Upper Crust Using the Magnetotelluric Data Along a Transect Across the Korean Peninsula (한반도 횡단 자기지전류 탐사에 의한 상부 지각의 지전기적 구조 연구)

  • Lee, Choon-Ki;Kwon, Byung-Doo;Lee, Heui-Soon;Cho, In-Ky;Oh, Seok-Hoon;Song, Yoon-Ho;Lee, Tae-Jong
    • Journal of the Korean earth science society
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    • v.28 no.2
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    • pp.187-201
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    • 2007
  • The first magnetotelluric (MT) transect across the Korean Peninsula was obtained traversing from the East Sea shoreline to the Yellow Sea shoreline. The MT survey profile was designed perpendicular to the strike of the principal geologic structure of the Korean Peninsula $(N30^{\circ}E)$, so-called 'China direction'. MT data were achieved at 50 sites with spacings of $3{\sim}8km$ along the 240 km survey line. The impedance responses are divided into four subsets reflecting typical geological units: the Kyonggi Massif, the Okchon Belt, the western part of the Kyongsang Basin, and the eastern part of the Kyongsang Basin. In the western part of the Kyongsang Basin, the thickness of the sedimentary layer is estimated to be about 3 km to 8 km and its resistivity is a few hundred ohm-m. A highly conductive layer with a resistivity of 1 to 30 ohm-m was detected beneath the sedimentary layer. The MT data at the Okchon Belt show peculiar responses with phase exceeding $90^{\circ}$. This feature may be explained by an electrically anisotropic structure which is composed of a narrow anisotropic block and an anisotropic layer. The Kyonggi Massif and the eastern part of Kyongsang Basin play a role of window to the deep geoelectrical structure because of the very high resistivity of upper crust. The second layers with highest resistivities in 1-D conductivity models occupy the upper crust with thicknesses of 13 km in the Kyonggi Massif and 18 km in the eastern Kyongsang Basin, respectively.

A Study on the Relationship Between Radial Growth and Climate Factors by Regions in Korean Pine (Pinus koraiensis) (지역별 잣나무의 연륜생장과 기후인자와의 관계 연구)

  • Lee, Sangtae;Bae, Sang-Won;Jang, Seok Chang;Hwang, Jaehong;Chung, Junmo;Kim, Hyun-Seop
    • Journal of Korean Society of Forest Science
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    • v.98 no.6
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    • pp.733-739
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    • 2009
  • This study was carried out to analyze the relationship between major climatic factors (monthly temperature, precipitation) and radial growth of Korean Pine (Pinus koraiensis) in Inje-gun(Mt. Seorak), Sanchung-gun and Namwon-si(Mt. Jiri). Radial growth measurements were crossdated and correlated with climate variables. The climatic factors used were monthly mean temperature and monthly precipitation from August of previous year to September of the current year. In Inje-gun, radial growth was negatively correlated with monthly mean temperature in April, May, June, and August of the current year and was positively correlated with precipitation in August, October of the previous year and in April, August of the current year. Sanchung-gun showed a negative correlation with monthly mean temperature in September of the previous year and August of the current year but positive correlation in January of the current year. In contrast, precipitation in September of the previous year and August of the current year showed a positive influence. The results suggest that high temperature together with low precipitation may thus cause water stress and thereby limit radial growth in this region. In Namwon-si, the climategrowth relationships show that radial growth was negatively correlated with monthly mean temperature in August, October of the previous year and June of the current year. But August of the previous year and May, August of the current year in precipitation was positively correlated with radial growth. In the study areas, precipitation plays an important role for the radial growth of Kroean Pine (Pinus koraiensis). The results suggest that precipitation is important in the radial growth because water deficit in trees would take place in response to high temperature in the study area. Also there was some differences with study areas in the effects of both climatic variables probably as a result of different stand structure and geographical conditions and micro-climate.

A Study of the Accidents of the Residents in a Rural Area (일개 보건진료소 사업 지역의 사고조사)

  • Kang, Pock-Soo;Lee, Kyeong-Soo;Kim, Seok-Beom;Kim, Chang-Yoon;Lee, Ok-Keum
    • Journal of Yeungnam Medical Science
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    • v.8 no.2
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    • pp.174-184
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    • 1991
  • To determine the incidence rate of accidents and its associated factors, a prospective survey was carried out in a rural area of a total of 1,360 residents for 1 year from January 1 to December 31, 1988 in Shin-am Ri, Jungdong Myun, Sangju Kun, Kyungpook Province. Data for accidents were collected by the community health practitioner who is working at Primary Health Post in Shin-am Ri. A total number of accident cases was 85 among 1,360 persons during one year study period, and annual incidence rate was 62.5 per 1,000 persons. The highest incidence rate of accident was observed in the age group of 30-39 was 179.8. The incidence rate of accident in male was 86.5 which was about 2 times that in female. In male, the highest incidence rate was seen in 30-39 age group and in female, 60-69 age group. The highest incidence rate of accident was observed in spring(29.4%) and summer(29.4%), and the lowest in fall(17.7%). The highest incidence rate of accident was observed in Friday(24.5%) by day of week, and between 9 a.m. to 12 a.m. by time zone. The most frequent use of medical facilities was Primary Health Post(51.8%) and the next was clinic(38.8%). Mean duration of treatment was 9.8 days. The accident occured in the room and kitchen(23.5%), in the yard and barn(23.5%), on the road(22.4%). and in the rice field and dry field(20.0%). The causes of accident were motor vehicle accident(20.0%), piercing or cutting(20.0%), collision or fighting(12.9%), and poisoning(11.8%) in order of frequency. The most common type of injury was open wound which was 43.5%. The most common tool of accident was farm machine which was 23.5%. The most common injuried part of body was extremity(55.3%).

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A Study on the Moderating Effect of Perceived Voluntariness in the Organizational Information System Usage and Performance (정보시스템 사용과 성과에 있어서 자발성의 조절효과에 관한 연구)

  • Lee, Seung-Chang;Lee, Ho-Geun;Jung, Chang-Wook;Chung, Nam-Ho;Suh, Eung-Kyo
    • Asia pacific journal of information systems
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    • v.19 no.2
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    • pp.195-221
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    • 2009
  • According to an industry report, a large number of organizations have invested in Organizational Information System(OIS) in the past few years. Several research results indicate that successful investments in OIS lead to productivity enhancement, while failed ones result in undesirable consequences such as financial losses and dissatisfaction among employees. In spite of huge investments, however, many organizations have failed in achieving the hoped-for returns from OIS. Thus, understanding user acceptance, adoption, and usage of new IS(Information Systems) is an important issue for IS practitioners. Indeed, study of the user acceptance of new information system has been one of the most important research topics in the contemporary IS literature. Several theoretical models are tested to examine 'user acceptance' and 'usage behavior' in IS context. While many research models incorporate 'ease of use' or 'usefulness' as important factors in explaining user acceptance, Technology Acceptance Model(TAM) has been one of the most widely applied models in user acceptance and usage behavior. Even in recent IS studies that employ theories of innovation diffusion in the area of IS implementation, a major focus has been on the user's perception of information technologies. In this research, we study 'voluntariness' as an important factor in IS acceptance by users. Voluntariness is defined as "the degree to which the use of the innovation is perceived as being voluntary, or of free will" When examining the diffusion of accepting OIS, a thoughtful consideration should be given to 'perceived voluntariness.' Current article has following research questions: 1) What models are appropriate to explain the success of OIS? and 2) How does the 'voluntariness' affect the success of OIS? In order to answer these questions, a research model is proposed to describe the detailed nature of association among three independent variables (IT usage level, task interdependency, and organizational support), a mediating variable (IS usage), a dependent variable (perceived performance), and a moderating variable(perceived voluntariness). The central claim of this article is that organizations hardly realize expected returns from OIS investments unless perceived voluntariness is effectively managed after operating OIS. As an example of OIS in this study we have selected the Intranet of Republic of Korea Air Force (ROKAF). ROKAF has implemented the Intranet in an attempt to improve communication and coordination within the organization. To test our research model and hypotheses, survey questionnaires were first sent out to 400 Intranet users. With the assistance of ROKAF, Intranet users were initially identified among its members, and subjects were randomly drawn from the pool. 377 survey responses were finally returned. The unit of measurement and analysis in this research is a personal level. Path analysis based on structural equation modeling was used to test research hypotheses. Construct validity represents accordance between the theoretical base concept of constructs and its measurement items. Tests for the reliability and discriminant validity are accepted, thus verifying our survey instrument. In this research, we have proposed a conceptual framework to highlight the importance of perceived voluntariness after organization deploys OIS. The results of our analysis present several key finding. First, all three independent variables (IT usage level, task interdependency, and organizational support) have significant effects on IS usage, which will eventually improve performance. Thus, IS usage plays a mediating role between antecedent variables (IT usage level. task interdependency, and organizational support) and performance improvement. Second, the effect of the task dependency was the highest for IS usage among the three antecedent variables. This is highly plausible since one of the Intranet's major capabilities is to facilitate communication among members within an organization. Accordingly, we conclude that the higher the task dependency, the higher Intranet usage. The effect of user's IT usage level was the second, while the effect of the organizational support was the third. Finally, the perceived voluntariness plays a pivotal role in enhancing perceived performance in personal level after launching the Intranet. Relationships among investigated variables were significantly different between groups with a high level and a low level of voluntariness. The impact of the Intranet usage on the performance was greater in the higher level voluntariness group than in the lower one. For the lower level voluntariness group, the user's IT usage had the highest effect on the Intranet usage among the three antecedent variables. In short, our study suggests that the higher the perceived voluntariness is the more IS usage will be. Perceived voluntariness was found to have a moderating effect on the relationships among user IT usage level, task interdependency, IS usage, and perceived performance, supporting all the hypotheses on the moderating effect. Most of all, user IT usage level has the strongest influence on IS usage, indicating that users with superior IT usage are more likely to enjoy a high level of perceived performance.