• Title/Summary/Keyword: 차단층

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Anti-Angiogenic and Anti-Cell Adhesion Effect of the Camellia japonica Flower Extract (동백꽃 추출물의 신생혈관생성 및 세포부착 억제 효과)

  • Heo, In-Do;Seo, Hyo-Jin;Kim, Jong-Deog
    • Journal of Life Science
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    • v.17 no.8 s.88
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    • pp.1152-1156
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    • 2007
  • The Camella japonica flower(CJF) extract was studied for their anti-angiogenenic and anti-cell adhesion effect. CJF-extract inhibited the tube formation on human umbilical vein endotherial cells(HUVEC) with butanol extract by 70.2%, acetone extract by 54.2%, ethyl acetate extract by 37.0%, chloroform extract by 21.2%. Cell adhesion molecules were effectively suppressed at different concentration of CJF at 50, 100, 200 ug/well such as for intercellular adhesion molecule(ICAM) by 5.9%, 29.4% and 52.9%, for vascular cell adhesion molecule(VCAM) by 12.5%, 43.8% and 62.5%, for E-selectin by 7.1%, 21.4% and 35.7%, respectively. Signal molecules of vascular endotherial growth factor receptor 2(VEGFR2), ${/beta}$-catenin and PI3K are inhibited by different concentration of CJF at 10, 20 and 30 ${\mu}g/mL$ with western blot. Angiogenesis will be inhibited with suppressing NF-kB molecule resulted in signal molecules blocked by CJF. CJF will be useful materials for treatment of angiogenesis related diseases such as cancer, metastasis, rheumathioid arthritis and obesity.

Applicability Estimation of Ballast Non-exchange-type Quick-hardening Track Using a Layer Separation Pouring Method (층 분리주입을 이용한 도상자갈 무교환방식 급속경화궤도의 적용성 평가)

  • Lee, Il Wha;Jung, Young Ho;Lee, Min Soo
    • Journal of the Korean Society for Railway
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    • v.18 no.6
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    • pp.543-551
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    • 2015
  • Quick-hardening track (QHT) is a construction method which is used to change from old ballast track to concrete track. Sufficient time for construction is important, as the construction should be done during operational breaks at night. Most of the time is spent on exchanging the ballast layer. If it is possible to apply the ballast non-exchange type of quick-hardening track, it would be more effective to reduce the construction time and costs. In this paper, pouring materials with high permeability are suggested and a construction method involving a layer separation pouring process considering the void condition is introduced in order to develop ballast non-exchange type of QHT. The separate pouring method can secure the required strength because optimized materials are poured into the upper layer and the lower layer for each void ratio condition. To ensure this process, a rheology analysis was conducted on the design of the pouring materials according to aggregate size, the aggregate distribution, the void ratio, the void size, the tortuosity and the permeability. A polymer series was used as the pouring material of the lower layer to secure the void filling capacity and for adhesion to the fine-grained layer. In addition, magnesium-phosphate ceramic (MPC) was used as the pouring material of the upper layer to secure the void-filling capacity and for adhesion of the coarse-grained layer. As a result of a mechanics test of the materials, satisfactory performance corresponding to existing quick-hardening track was noted.

Characteristics of Groundwater Levels Fluctuation and Quality in Ddan-sum Area (낙동강 하중도 딴섬의 지하수위 변동 및 수질 특성)

  • Kim, Gyoobum;Choi, Doohoung;Shin, Seonho
    • Journal of the Korean GEO-environmental Society
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    • v.12 no.2
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    • pp.35-43
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    • 2011
  • Confined aquifer, which is separated with upper clayey or silty materials, is partially distributed at the depths of the sediments in Ddan-sum area on the lower Nakdong river. Measurements of groundwater levels at 13 sites explain that groundwater flow shows seasonally various due to seasonal rainfall and agricultural water use. From 9 long-term monitoring data of groundwater levels at 7 sites, 3 types of groundwater levels time series can be classified using principal component analysis. The first type is seen in the center of Ddan-sum and has a round-shape graph due to a weak response to stream water levels. The second type exists in the outer part of Ddan-sum and shows sharply peak-shape graph due to a rapid and strong response to stream water levels and rainfall. The last type, which is seen in a deep layer, has a periodicity by tital effect. From geochemical analysis at each monitoring sites, [$Ca-HCO_3$] type happens in the center of Ddan-sum far from Nakdong river, and [$Na-HCO_3$] and [$Ca-SO_4(Cl)$] types exist in the outer of Ddan-sum affected by river quality.

Case History of Sea Dyke Filter Construction Using Geotextile Tube Mattress (튜브형 매트리스를 활용한 방조제 필터공 축조사례연구)

  • Oh, Young-In;Yoo, Jeon-Yong;Kim, Hyun-Tae
    • Journal of the Korean Geosynthetics Society
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    • v.6 no.1
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    • pp.9-16
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    • 2007
  • Geotextile is one of the most useful and effective polymer material in civil construction works and the main function of geotextile is separation, reinforcement, filtering and drainage. Recently, because of the shortage of natural rock, traditional forms of river and coastal structures have become very expensive to build and maintain. Therefore, the materials used in hydraulic and coastal structures are changing from the traditional rubble and concrete systems to the cheaper materials and systems. One of these alternatives employs geotextile tube technology in the construction of coastal and shore protection structures, such as embankment, see dyke, groins, jetties, detached breakwaters and so on. Geotextile tube technology has changed from being an alternative construction technique and, in fact, has advanced to become the most effective solution of choice. This paper presents case history of sea dyke filter construction using geotextile tube mattress and also, various issues related to the tube mattress design and construction technology.

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Characteristic of Permeability with the Sand, Calcium Bentonite and Solidifier Mixtures according to Selective Reaction of TCE (트리클로로에틸렌(TCE) 선택적 반응에 따른 모래, 칼슘-벤토나이트 및 겔화제 혼합차수물의 투수 특성)

  • Yun, Seong Yeol;Choi, Jeong Woo;Oh, Minah;Lee, Jai-Young
    • Journal of the Korean Geosynthetics Society
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    • v.19 no.1
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    • pp.25-33
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    • 2020
  • To improvement the swelling characteristics of the existing cutoff wall against the moisture, the permeability of the sand, calcium bentonite and solidifier mixture according to the contact with trichloroethylene (TCE) was evaluated. Characteristics analysis and the permeability test of the research materials were performed. The permeability was decreased as the mixing ratio of the calcium bentonite was increased and it was increased as the mixing ratio of the solidifier was increased. In conclusion, when mixing 15% of calcium bentonite and more than 30% of solidifier, the permeability coefficient in the underground water movement was analyzed as more than α × 10-4 cm/sec showing that it does not block the underground water movement. In addition, as the permeability coefficient of mixtures after TCE reaction was analyzed as less than α ×10-7 cm/sec, it satisfied the condition of blocking layer (less than 1.0 × 10-6 cm/sec). Therefore, the calcium bentonite and solidifier can be utilized as barrier that showing the characteristic of percolation ability conversion in soil and underground water contaminated with TCE.

Evaluation of floor impact sound and airborne sound insulation performance of cross laminated timber slabs and their toppings (구조용 직교 집성판 슬래브와 상부 토핑 조건에 따른 바닥충격음 및 공기전달음 평가)

  • Hyo-Jin Lee;Yeon-Su Ha;Sang-Joon Lee
    • The Journal of the Acoustical Society of Korea
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    • v.42 no.6
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    • pp.572-583
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    • 2023
  • Demand for wood in construction is increasing worldwide. In Korea, technical reviews of high-rise Cross Laminated Timber (CLT) buildings are under way. In this paper, Floor Impact Sound Insulation Performance (FISIP) and Transmission Loss (TL) of 150 mm thick CLT floor panels made of two domestic species, Larix kaempferi and Pinus densiflora, are investigated. The CLT slabs were tested in reverberation chambers connected vertically. When comparing Single Number Quantity (SNQ) of FISIP of the bare panels, the Larix CLT is 3 dB lower in heavy-weight and 1 dB in light-weight than the Pinus CLT. However, there was no difference when concrete toppings were added to improve the performance. As the concrete toppings became thicker, the heavy-weight was reduced by 9 dB ~ 20 dB, and the light-weight by 20 dB ~ 30 dB. And the analysis of these results with area density has confirmed that the area densities are highly correlated (R2 = 0.94 ~ 0.99) to the FISIP of the CLT. The types of CLT didn't affect the TL. Comparison of theoretical TL values with measured TL values has shown that the frequency characteristics are similar but 8 dB ~ 12 dB lower in measured values. The relationship between the TL and frequency characteristics of the tested CLT slabs was derived by using the correction value.

Sensitivity and Self-purification Function of Forest Ecosystem to Acid Precipitation (II) - Ion Balance in Vegetation and Soil Leachate - (산성우(酸性雨)에 대한 산림생태계(山林生態系)의 민감도(敏感度) 및 자정기능(自淨機能)(II) - 식생층(植生層)과 토양층(土壤層) 용탈(溶脫)이온 분석(分析)을 중심으로 -)

  • Chang, Kwan Soon;Lee, Soo Wook
    • Journal of Korean Society of Forest Science
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    • v.84 no.1
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    • pp.103-113
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    • 1995
  • To estimate buffer capacity and sensitivity of forest ecosystem to acid rain in Taejon, ionic components of throughfall, stemflow, soil leachate, and open rain in Pinus rigida and Quercus variabilis forest were analysed. The spatial sensitivity based on parent rock and forest type was given by IDRISI of GIS which created imagery conversion from soil and vegetation map. Parent rocks and soils were classified into acidic, sedimentary, metamorphic rock and then subdivided based on $SiO_2$ content. Average pH of vegetation leachate was higher in throughfall but lower in stemflow than open rain and higher in Quercus variabilis forest than in Pinus rigida forest. The flow of $SO{_4}^{2-}$, $NO_3{^-}$ and $Cl^-$ through vegetation leaching(throughfall plus stemflow) into soil were 7.2, 4.3, and 2.5 times, respectively, higher in Pinus rigida forest and 4.4, 2, and 2.5 times, respectively, higher in Quercus variabilis forest than in open field. But the concentration of exchangeable cations was 4.1 times higher in Pinus rigida forest and 4.6 times higher in Quercus variabilis forest than in open field. Average pH of soil leachate was lower than that of throughfall, but higher than that of stemflow. The concentration of exchangeable canons and $Al^{3+}$ in soil leachate were more in Pinus rigida forest than in Quercus variabilis forest and increase signficantly with the increase of acidic deposits. Pinus forest had more deposition and canopy interception of acidic pollutants and more nutrient loss than Quercus forest, and Quercus forest had more cation exchange and proton consumption and than consequently had less nutrient loss and better buffer capacity than Pinus forest. The 69% of forest soils was distributed on acidic rock, 25% of it on metamorphic rock, and 6% of it on intermediate and basic rock. Acidic rock residuals which had low very canon exchange capacity and high sensitivity to acid rain occupied a half of total forest land in Taejon area. Therefore forests in Taejon showed high vulnerability to acid rain and will receive much more stress with the increase of acid rain precursors.

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Geophysical Investigation of Gas Hydrate-Bearing Sediments in the Sea of Okhotsk (오호츠크해 가스하이드레이트 퇴적층의 지구물리 탐사)

  • Jin, YoungKeun;Chung, KyungHo;Kim, YeaDong
    • Journal of the Korean Geophysical Society
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    • v.7 no.3
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    • pp.207-215
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    • 2004
  • As the sea connecting with the East Sea, the Sea of Okhotsk is the most potential area of gas hydrates in the world. In other to examine geophysical structures of gas hydrate-bearing sediments in the Sea of Okhotsk, the CHAOS (hydro-Carbon Hydrate Accumulation in the Okhotsk) international research expedition was carried out in August 2003. In the expedition, high-resolution seismic and geochemical survey was also conducted. Sparker seismic profiles show only diffusive high-amplitude reflections without BSRs at BSR depth. It means that BSR appears to be completely different images on seismic profiles obtained using different frequencies. Many gas chimneys rise up from BSR depth to seafloor. The chimneys can be divided into two groups with different seismic characteristics; wipe-out (WO) and enhanced reflection (ER) chimneys. Different seismic responses in the chimneys would be caused by amount of gas and gas hydrates filling in the chimneys. In hydroacoustic data, a lot of gas flares rise up several hundreds meters from seafloor to the water column. All flares took placed at the depths within gas hydrate stability zone. It is interpreted that gas hydrate-bearing sediments with low porosity and permeability due to gas hydrate filling in the pore space make good pipe around gas chimneys in which gas is migrating up without loss of amount. Therefore, large-scale gas flare at the site on gas chimney releases into the water column.

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Preparation and Characteristics of Multilayer Lamellar Vesicle Using Phosphate Ester Surfactant (Phosphate ester 계면활성제를 이용한 다중층 라멜라 베시클의 제조 및 특성)

  • Kim, Young-Ho;Lee, Sang-Gil;Jung, Eun-Ji;Lee, Dong-Won;Pyo, Hyeong-Bae;Lee, Dong-Kyu
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.2
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    • pp.280-289
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    • 2013
  • Various vehicles have been studied in order to protect skin ageing and sustain constantly moisturization. Recently, in relation to maintain of moisture, absorption and penetration of active materials, there has been introducing many preparing methods such as liposome, liquid crystal and multilamellar emulsion. We developed multilayer lamellar vesicle using cetearyl alcohol/ceteth-20 phosphate/dicetyl phosphate as analogy of phospholipid according to variation of shear rate and pH. These multilayer lamellar vesicles were confirmed by cross polarizing microscope. As results, morphologies of lamellar vesicle were not uniformed at low shear rate and pH. Also, stabilities for encapsulation of retinol were observed at $42^{\circ}C$ during two months. As a result, quantitative content of retinol decreased at low pH. Multilayer lamellar vesicle decreased 14% of transepidermal water loss compared with O/W emulsion. We compared multilayer lamellar sun cream to O/W sun cream using in vitro SPF test of water resistance and concluded that multilayer lamellar sun cream is similar to O/W sun cream in water resistance.

A Study on Improving Installation Guideline of Facilities to Protect Groundwater Contamination: Applications of Packer Grouting to Contaminated Wells (지하수오염방지 시설기준의 개선에 관한 연구:지하수오염관정에의 팩커그라우팅 적용사례)

  • Choo, Chang-Oh;Ryu, Jong-Heum;Cho, Heuy Nam;Jeong, Gyo-Cheol
    • The Journal of Engineering Geology
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    • v.23 no.3
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    • pp.293-304
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    • 2013
  • Because the present groundwater law broadly regulates a simple and impractical guideline ignoring aquifer characters and geology, general purpose facilities for protection of groundwater contamination is still considered unsatisfactory to ensure groundwater resources. In recent, there have been growing attempts in the packer development as crucial techniques and devices for groundwater protection. This study investigated the application of packer grouting techniques to contaminated groundwaters of two well sites in the Andong and Yeongi areas, both of which revealed a satisfactory effect with improved water quality: 94% decrease in turbidity at the Andong area and 60% decrease in $NO_3$-N, respectively. Based on aquifer characters including geology, weathering depth, fracture pattern, hydraulic gradient, and the flow path of contaminants, the integrated properties of groundwater contamination should be evaluated and treated with the help of accurate analyses such as bore hole imaging and monitoring data. Packer grouting and casing on well to ensure the useful aquifer free of contaminant are expected to play important role in inhibiting the inflow of contaminants when adequately applied. Therefore it is concluded that these can serve as reliable tools in remediation and protection of contaminated groundwater as well as efficient utilization of groundwater.