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http://dx.doi.org/10.12925/jkocs.2013.30.2.280

Preparation and Characteristics of Multilayer Lamellar Vesicle Using Phosphate Ester Surfactant  

Kim, Young-Ho (R&D Center, Hanbul Cosmetics Co. Ltd.)
Lee, Sang-Gil (R&D Center, Hanbul Cosmetics Co. Ltd.)
Jung, Eun-Ji (R&D Center, Hanbul Cosmetics Co. Ltd.)
Lee, Dong-Won (R&D Center, Hanbul Cosmetics Co. Ltd.)
Pyo, Hyeong-Bae (R&D Center, Hanbul Cosmetics Co. Ltd.)
Lee, Dong-Kyu (Department of Industrial Chemistry, College of Engineering, Chungbuk National University)
Publication Information
Journal of the Korean Applied Science and Technology / v.30, no.2, 2013 , pp. 280-289 More about this Journal
Abstract
Various vehicles have been studied in order to protect skin ageing and sustain constantly moisturization. Recently, in relation to maintain of moisture, absorption and penetration of active materials, there has been introducing many preparing methods such as liposome, liquid crystal and multilamellar emulsion. We developed multilayer lamellar vesicle using cetearyl alcohol/ceteth-20 phosphate/dicetyl phosphate as analogy of phospholipid according to variation of shear rate and pH. These multilayer lamellar vesicles were confirmed by cross polarizing microscope. As results, morphologies of lamellar vesicle were not uniformed at low shear rate and pH. Also, stabilities for encapsulation of retinol were observed at $42^{\circ}C$ during two months. As a result, quantitative content of retinol decreased at low pH. Multilayer lamellar vesicle decreased 14% of transepidermal water loss compared with O/W emulsion. We compared multilayer lamellar sun cream to O/W sun cream using in vitro SPF test of water resistance and concluded that multilayer lamellar sun cream is similar to O/W sun cream in water resistance.
Keywords
multilayer lamellar vesicle; phosphate ester surfactant; transepidermal water loss; water resistance SPF; phospholipid;
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Times Cited By KSCI : 1  (Citation Analysis)
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