• Journal of the Korean Data and Information Science Society
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• v.20 no.1
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• pp.149-158
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• 2009

Tsutsugamushi fever occupies more than 80% of total fall epidemic diseases and has an incubation period of 1 or 2 weeks as well. We have assumed that the incubation period distribution is gamma and therefore, reach an agreement that the infected distribution is normal with ${\hat{\mu}}=309.92$, ${\hat{\sigma}}=14.154$ by back calculation method. The infection cases are found severely large around the month of October. The infection case distribution demonstrates the incidence number increasing rapidly and progresses fast during the month of November. In this study, we have calculated the future prevalence number of maximum 1,200 people by inferred infection probability and incubation period distribution with some sort of limitation that the trend of increasing incidence number is not taking into an account. We considered the SIRS model which is also known as epidemic model, familiar to interaction between epidemiological classes. Our estimated parameters converged well with the initial parameter values.

• Journal of Korean Biological Nursing Science
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• v.5 no.1
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• pp.35-44
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• 2003

Objectives : Though Tsutsugamushi disease has been reported with increasing frequencies in rural communities in Korea, it is not easy to find the nursing investigations. Methods : We have conducted a survey on 30 cases who had the fever as a chief complaint, then clinically ruled out the Tsutsugamushi disease in autumn of $2000{\sim}2001$. Data were collected retrospectively by investigation of the general characteristics, clinical and laboratory findings, their nursing care. Findings: Of 30 cases, 46.7% were farmers, and 60.0% had chances of exposure to fields or mountains. The characteristic symptoms and signs were febrile sense and chill(100.0%), headache(80.0%), and eschar(66.7%). Abnormal laboratory findings were anemia (23.3%), elevated AST(60.6%), ALT(63.3%), and abnormal urinalysis findings(50.0%). 53.3% were serologically confirmed as Tsutsugamushi disease. Therapeutic nursing cares were composed with warm up by blancket(50.0%), Ice bag(50.0%) and doxycycline antibiotic therapy(100.0%). Other nursing care for them included fluid therapy(100.0%) and nutritional support with regular(56.7%) or soft diet(43.3%). Conclusion: The above results indicate nurses who take care of acute febrile clients should make her responsible for the fever and pain management as well as give education for infection control for the community inhabitants.

• 대한예방의학회:학술대회논문집
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• 2005.10a
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• pp.482-482
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• 2005

• Tuberculosis and Respiratory Diseases
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• v.62 no.6
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• pp.545-548
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• 2007

쯔쯔가무시병은 추수 시기에 유행하는 대표적인 급성 열성질환으로 여전히 증가 추세에 있다. 의심되는 환자에게 Doxycycline 투여 후 급속한 해열이 질환의 독특한 특징이기도 한데 Doxycycline 투여 96시간 후에도 지속적인 고열과 근육통이 있었던 환자에게 Clarithromycin으로 변경 후 급속한 해열과 함께 증상이 호전된 증례를 보고한다.

• Journal of Medicine and Life Science
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• v.15 no.2
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• pp.84-88
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• 2018

The aim was to evaluate different results from using crude incidence rate (CIR) instead of agestandardized incidence rate (AIR) when comparing groups having different age structures. After selecting a report using CIRs, AIRs and their 95% confidence intervals(CI) was calculated from the raw data. The statistically significant difference between CIR and AIR was decided based on AIR's 95% CI. Comparing with CIRs, AIRs were under-estimated. In addition, there were no statistical significance of annual trends(P=0.59). These findings are an additional evidence using AIR when comparing level of occurring infectious diseases on groups with different age structures.

• Clinical Pain
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• v.18 no.2
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• pp.111-114
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• 2019

Guillain-Barre syndrome (GBS) is usually characterized by acute areflexic ascending paralysis with minimal sensory involvement. Only a few cases of GBS associated with scrub typhus have been reported. Previous case reports focused on the laboratory findings, pathogenesis, and clinical manifestation. Unlike the previous case, neuropathic pain was a prominent symptom of GBS in our case. We report scrub-typhus-related GBS with a detailed description of the clinical manifestations, especially neuropathic pain, along with results of serial follow-up electrodiagnostic studies.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.3
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• pp.344-350
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• 2019

We investigated the distribution of chigger mites in Seogwipo, Jeju Island to conduct surveillance for the presence of Orientia tsutsugamushi. Using a total of 20 samplers, chigger mite larvas were sampled weekly from September to November in Rice field, Field, Waterway, and Glass field (4 locations), and we found up to 51 larvas of 3 different species of chigger mites. 64 field mice were captured when sampling for chigger mite-infested rodents in rice fields, waterways, fields, reservoirs and hills (5 locations) for 9 months from March, 2018 to November, using 100 Sherman traps with placing 20 traps in each location, and in each location the trap index was 0.08. Only back-striped field mice (Apodemus agrarius) were captured one at a time. They were most frequently captured in April with 15 mice, and then 436 chigger mites were collected from the total of 64 captured wild rodent, showing a chigger index of 6.8. The chigger index was the highest in November at 46.0, followed by 6.8 in July and 4.6 in June. PCR was performed to investigate if there were any O. tsutsugamushi hosts among the 487 chigger mites sampled from the captured rodents and this turned out to be negative.

• Annals of Clinical Neurophysiology
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• v.11 no.2
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• pp.71-73
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• 2009

Biclonal gammopathy is characterized by the presence of two different monoclonal immunoglobulins, and the clinical findings of biclonal gammopathy are similar to those of monoclonal gammopathy. An association between biclonal gammopathy and tsutsugamushi meningitis has not been reported previously. Here, we report a case of a 55-year-old man presented with fever and decreased mentality. A cerebrospinal fluid (CSF) test and an indirect immunofluorescent antibody test for Orientia tsutsugamushi revealed tsutsugamushi meningitis. CSF and serum immunofixation electrophoresis revealed biclonal gammopathy (IgG-${\kappa}$, IgG-${\lambda}$). His symptoms improved after antibiotics treatment, and serum biclonal gammopathy completely disappeared.

• The Journal of Korean Oriental Chronic Disease
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• v.10 no.1
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• pp.32-38
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• 2005

Scrub typhus is a acute febrile illness by Orientia tsutsugamushi that is endemic in Asian-Pacific areas. It is characterized by fever, rash, eschar, lymphadenopathy. Therapy with Tetracycline, Doxycycline, Chloramphenicol is currently recommended. Here we report a case of tsutsugamushi disease in a 66 year old man had fever, nausea, vommitting, dyspnea, who was successfully treated with East-West intergrative medicine therapy - Antibiotics therapy and Korean traditional medicine(Sasang medicine and acupuncture treatment) - and symptoms improved.

• Tuberculosis and Respiratory Diseases
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• v.70 no.3
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• pp.247-250
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• 2011

The pandemic (H1N1) 2009 influenza outbreak coincided with the typical Scrub typhus season, which can lead to diagnostic difficulties due to their similar and non-specific symptoms. Here we describe a case of laboratory confirmed co-infection of Pandemic (H1N1) 2009 influenza and Scrub typhus and discuss the difficulties in distinguishing the two illnesses clinically.