• Title/Summary/Keyword: 집단유전학

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Genetic discrimination as another shadow of biotechnology (생명과학기술의 또 다른 그늘: 유전자차별)

  • Kim, Sang Hyun
    • Journal of Science and Technology Studies
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    • v.14 no.1
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    • pp.59-85
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    • 2014
  • This study aims to highlight the social aspects of genetic discrimination as another shadow that biotechnology can influence on social life. To do so, the definition of "genetic discrimination" and three perspectives (exceptionalism, expressivism, and human right discourse) were reviewed. In addition, the Genetic Information Nondiscrimination Act (GINA) of the United States and the Bioethics and Safety Act of Korea were analyzed. Several social implications for establishing the research and policies of genetic discrimination based on the existing research results of perceived genetic discrimination (the experiences, fears, and coping strategies of genetic discrimination) were suggested. These included public consensus on the definition of genetic discrimination and emphasis on a human rights approach against genetic discrimination; concerns regarding genetic discrimination in both the personal and public domains; raising the consciousness of both health care providers and the public regarding genetic discrimination; and developing psycho-social coping strategies for decreasing the fear of discrimination of asymptomatic people (hereditary carriers).

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Dynamic Development of Techno-social Dysfunctions Accompanied with the Spread of 'New technology' and Countermeasures against Them (신기술' 확산에 따른 기술사회적 역기능의 전개과정 및 대응 전략)

  • Kim Jong-Kil
    • Journal of Science and Technology Studies
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    • v.1 no.1 s.1
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    • pp.235-259
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    • 2001
  • This study investigates a variety of dysfunctions and dynamics accompanied with the spread of advanced technology, and predicts the developmental directions of future uncertain society. There are, further, proper countermeasures against dysfunctions discussed. First, different theoretical paradigms concerned with the relationship between seience/technology and society would be comparatively analyzed, and their techno-social implications would be examined. Next, the latest trend of bio-technology and information technology, especially the trend of combination of bio- and information technology, appeared in the progress of Human Genome Project, would be considered. Thirdly, techno-social dysfunctions and far-reaching effects following the development of high-technologies would be analyzed, and realistic alternative plans would be suggested. Through this study, we come to a conclusion that, in order to reduce techno-social dysfunctions to a minimum and enhance their eufunctions, not only 'human' control over technological development should be guaranteed, but also action plan for bridging social gaps should be prepared. In addition, fluent communication and mutual understanding of all concerned, particularly between researcher community, government, and civic sector are required.

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Multiple Maternal Origins of Korean Native Chicken Based on the mtDNA D-loop Variation (mtDNA D-loop 변이로 확인된 한국재래닭의 다양한 모계기원)

  • Cho, Chang-Yeon;Lee, Pung-Yeon;Ko, Yeoung-Gyu;Kim, Hak-Kyu;Park, Mi-Na;Yeon, Seung-Hum
    • Korean Journal of Poultry Science
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    • v.38 no.1
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    • pp.5-12
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    • 2011
  • In this study, we analyzed the mitochondrial DNA D-loop region of Korean native chicken to clarify their phylogenetic relationships, possible maternal origin and routes of introduction into Korea. A 1231-1232 bp DNA fragment from the mtDNA D-loop region was sequenced in 315 chickens from 11 populations, Thirty-five variable sites that defined 21 haplotyes were observed. In Korean native chicken, diversity accounted for 90% of the variation, little differentiation among the strains. The 21 haplotypes clustered into 5 clades which were A, B, C, D and E. These results indicate that Korean chickens were derived from China with multiple origins.

Sympatry and Species Status of Momco Jagowskii and M oxycephalus (Cyprirndae) (버들개(Moroco lagowskii)와 버들치(M.oxcephalus)의 동서지역 분석 및 종 문제에 관하여)

  • 양서영;민미숙
    • The Korean Journal of Zoology
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    • v.31 no.1
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    • pp.56-61
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    • 1988
  • The taxonomic status of Moroco Jagowskii and M oxycephalus a pair of sibling species inhabiting in Korean fresh waters, has been unclear up to date. Recently a sympatric area of these species was found (Kang, 1987). The purpose of this study was to clarify their specific status by analysing specimens collected from the sympatric area of these species. Isozyme analysis and morphometric comparison were performed. Among 26 loci screened 6 loci (Aco, Est-2, E-X, Gk-3, Ipo, Me) showed fixed allelic difference between them and these loci could be used as genetic markers to distinguish them. Isozyme analysis indicates that no hybridization occurs and therefore it is assumed that isolating mechanism is completed and they are distinct species. The mean number of scales above lateral line (SAL) of M Jagowskii and M oxycephalus at sympatric area was 24.93 $\pm$1.95 and 17.33$\pm$0.72 respectively, and it seems as the result of character displacement. A finer microhabitat segregation between them is noticed. M oxycephalus is found along the effluent streams whereas M lagowskii is distributed mostly in the main stream at sympatric area.

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An Outbreak of Gregarious Nymphs of Locusta migratoria (Orthoptera: Acrididae) in Korea and Their Genetic Lineage Based on mtDNA COI Sequences (한국에서 군집형 풀무치의 대발생과 그 집단의 유전적 계통)

  • Lee, Gwan Seok;Kim, Kwang Ho;Kim, Chang Seok;Lee, Wonhoon
    • Korean journal of applied entomology
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    • v.55 no.4
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    • pp.523-528
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    • 2016
  • The migratory locust Locusta migratoria, one of the world's most notorious insect pests, has polyphenic (gregarious or solitarious) characteristics. Although this species is known to have several morphological variants, it is genetically divided into two different lineages using mitochondrial genome analysis: Southern (Africa, Southern Europe, Southern Asia, and Australia) and Northern (East Asia and the Eurasian continent). In 2014, a large number of orange black-colored gregarious L. migratoria nymphs suddenly appeared at Haenamgun, Jeollanamdo in the south of Korea. This is the first report of gregarious phase locusts occurring in Korea. In this study, mitochondrial COI sequences of one nymph and 11 adults of L. migratoria were analyzed to examine the genetic lineage of the gregarious nymphs of L. migratoria. Our results showed that all 12 individuals belong to the Northern linage and have low intraspecific genetic divergences (0.0% - 0.9%).

Inheritance of Resistance to Gall Mite(Eriophys macrodonis) in Boxthorn (Lycium chinese) Cultivars (구기자품종의 구기자혹응애 저항성 유전)

  • 최재을;차선경;김영창;김진희;강희경
    • Korean Journal of Plant Resources
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    • v.15 no.3
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    • pp.298-304
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    • 2002
  • The inheritance of resistance to gall mite(Eriophys macrodonis) in boxthorn cultivars was studied with plants infected in open field. Segregation of the F$_1$ generation from crosses between resistant cultivars(Japan 1 and China 1) and susceptible line(CL42-56) hits a 3 resistant : 1 susceptible ratio, and the segregation ratio was 15 : 1 in cross between Japan 1 and China 1. It is concluded that gall mite resistance seemed to be controlled by two duplicate genes(El and E2), such that E1e1E2e2 symbolize the genotypes of China 1 and Japan 1. However, F, generation from Chungyanggugiza and CL42-56 cross did not showed clear segregation pattern but continuous variation was observed against gall mite resistance when resistance was determined on the basis of the percentage of galled leaves. Results indicated that the inheritance of resistance in Chungyanggugiza may be polygenic and complex. Also, Japan 1 and China 1 has a strong potential as a source of gall mite resistance, and Chungyanggugiza showing less resistance still has a valuable source.

Estimation of Genetic Parameters for Growth-related Traits of Two Korean Abalone Subspecies, Haliotis discus hannai and H. discus discus, by using Multiple Traits of Animal Model in Early Growth Period (다형질 Animal Model에 의한 한국산 전복 2 아종의 초기 치패의 성장관련 형질에 대한 유전모수 추정)

  • Choe, Mi-Kyung;Han, Seock-Jung;Yang, Sang-Geun;Won, Seung-Hwan;Park, Choul-Ji;Yeo, In-Kyu
    • The Korean Journal of Malacology
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    • v.23 no.2
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    • pp.217-225
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    • 2007
  • This study was conducted to estimate the general genetic parameters, heritabilities, and genetic and phenotypic correlations on growth-related traits by studying multiple trait animal model in two Korean abalone species, Haliotis discus hannai and H. discus discus. The data was collected from the records of 3,795 individuals produced from 54 sires and 74 dams in Haliotis discus hannai and 399 individuals produced from 7 sires and 7 dams in Haliotis discus discus. The data was evaluated by the Genetics and Breeding Research Center, National Fisheries Research & Development Institute (NFRDI). Genetic parameters were estimated for two abalone species raised in Bukjeju branch, NFRDI, from May 20 to November 1, 2004. The heritability estimates for growth traits of shell length, shell width and body weight obtained from restricted maximum likelihood (REML) were ranging from 0.73 to 0.78 in Haliotis discus hannai, and from 0.87 to 0.89 in H. discus discus. The heritabilities for shell shape and condition factor were ranging from 0.17 to 0.20 in Haliotis discus hannai, and from 0.01 to 0.45 in H. discus discus. Genetic and phenotypic correlations were over than 0.96 between shell parameters and weight in both of abalone subspecies, indicating that breeding for weight gains could successfully be achieved by selecting for shell length.

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Phylogeographic study of Abies koreana and Abies nephrolepis in Korea based on mitochondrial DNA (미토콘드리아 DNA 분석을 통한 구상나무와 분비나무의 계통지리학적 연구)

  • Yang, Jong-Cheol;Yi, Dong-Keun;Joo, Min-Jeong;Choi, Kyung
    • Korean Journal of Plant Taxonomy
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    • v.45 no.3
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    • pp.254-261
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    • 2015
  • Genetic variations of Abies koreana and Abies nephrolepis were assessed using two mitochondrial DNA regions (nad5 intron 4 and nad5 intron 1) for 16 natural populations to understand their phylogeographical history. Seven polymorphic sites of the two combined regions resulted in the resolution of four haplotypes (M1-M4). The average gene diversity within the population ($H_S$) was 0.098, the total gene diversity ($H_T$) was 0.620, and the interpopulation differentiation was $G_{ST}=0.841$, $N_{ST}=0.849$. The populations were divided into three groups (northern area, central area, southern area) according to their geographic locations. The populations of the northern and southern areas were mostly fixed for M1 and M2, respectively. The populations of the central area showed the highest levels of gene diversity ($H_T=0.654$) due to introgression from the northern area and southern area. The presence of a single mtDNA haplotype in the southern area suggests that current widespread populations have expanded to the central area from a specific refugium population after the last glacial period.

STUDY ON THE GENOTYPIC AND ENVIRONMENTAL CORRELATION BETWEEN THE NUMBER OF THE EGG MARKINGS AND OTHER METRIC CHARACTERS, IN SILKWORM, Bombyx mori L. (잠란의 반문수와 타계량형질과의 유전상관과 환경상관에 관한 연구)

  • 박광의
    • Journal of Sericultural and Entomological Science
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    • v.2
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    • pp.41-47
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    • 1962
  • This work was carried out to investigate the phenotypic, genotypic, and environmental correlations between the number of the egg markings and other metric characters, and their heritability, with eight varieties in Bombyx mori L. Five European varieties, ten Chinese varieties and ten Japanese varieties were used to know the average number of the egg markings and their variabilities for each strains. The results may be summarized as follows: 1) there were highly negatively phenotypic and genotypic correlations between the number of the egg markings and total cocoon weight, weight of cocoon layer, or denier, but not an environmental correlation. 2) The average number of the egg markings in Chinese strain was more than that in other strains. 3) The correlation between the motality and the number of egg markings seemed not to be found. 4) The heritability of the weight of cocoon layer and the bave length was less than that of total cocoon weight, denier and number of egg markings. 5) The more the number of the polyhedral particles in an egg marking group became, the more the total number of egg markings increased. 6) The variation of the number of the egg markings in European strain was larger than that in any other strains. 7) It is expected that the selection for the number of the egg markings may have genetic advances of total cocoon weight, weight of cocoon layer, or denier. Especially the selection for the number of the egg markings before rearing will save the silkworm rearing cost.

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Detection of Imprinted Quantitative Traits Loci (QTL) for Reproductive and Growth Traits in Region of IGF II Gene on fig Chromosome (돼지 염색체상의 IGF II 유전자 인접 부위에서 번식 및 성장형질에 연관된 Imprinting 양적형질 유전자 좌위(QTL)의 탐색)

  • Lee, Hakkyo
    • Korean Journal of Animal Reproduction
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    • v.25 no.4
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    • pp.295-304
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    • 2001
  • Characterization of quantitative trait loci (QTL) was investigated in the experimental crosses between Berkshire and Yorkshire breed. A total of 525 F$_2$ progenies from 65 matting of F$_1$ Parents were produced. Phenotypic measurements included average daily gain (ADG), average back fat thickness (ABF), and loin eye area (LEA). To identify the presence of QTL for reproductive performance, birth weight (BWT) and body weight at 16 days (16DAY) were included as indirect trait. QTL segregation was deduced using 8 markers assigned to chromosome 2 (SSC2). Quantitative trait locus analyses were performed using interval mapping by regression under line-cross model. Presence of imprinting was tested under the statistical model that separated the expression of paternally and maternally inherited alleles. To set the evidence of QTL presence, significance thresholds were derived by permutation following statistical tests, respectively. Genome scan revealed significant evidence for three quantitative trait loci (QTL) affecting growth and body compositions, of which two were identified to be QTL with imprinting expression mode near the ICF II gene region. For average back fat thickness (ABF), a paternally expressed QTL was found on chromosome 2 (SSC2). A paternally expressed QTL affecting loin eye area (LEA) was found in the region of SSC2 where evidence of imprinted QTL was found for average back fat thickness (ABF). For average daily gain (ADG), QTL expressed with Mendelian mode was found on chromosome 2 (SS2). Also, QTL affecting average daily gain (ADC), was identified to be expressed with Mendelian express mode.

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