• Title/Summary/Keyword: 질환예측

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Clinical Approach to Diseases Related to TMJ Disorder (턱관절장애 관련 제질환의 임상적 접근)

  • Young Jun Lee
    • Journal of TMJ Balancing Medicine
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    • v.12 no.1
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    • pp.28-31
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    • 2022
  • 위에서 살펴본 바와 같이 나는 급성 턱관절장애의 경우, 첫번째 유형은 주로 턱관절 디스크공간의 문제와 하악의 위치를 바로잡아주는 근육의 문제가 주 원인일 것으로 추정하고 있다. 만약 턱관절 디스크공간이 정상공간이라면 턱의 지그재그 움직임이나 턱관절잡음, 턱통증, 턱탈구, 그리고 개구장애 등이 발생할 수 없기 때문이다. 그리고 근육의 문제 중에서는 턱관절 디스크원판을 양측에서 잡아주는 내외측 익돌근의 문제가 가장 많은 영향을 미치고 있다. 특히 내측 익돌근의 긴장 및 수축이 디스크 원판을 내측으로 빠져나가게 함으로써 하악의 좌우 지그재그 움직임을 야기시키고 턱관절잡음이나 턱통증 및 개구장애를 유발하기 때문이다. 나머지는 저작에 관여하는 근육들이 그 다음으로 영향을 미치는 것으로 예측하고 있다. 그러나 제2형 급성 턱관절장애의 경우는 제1형 급성 턱관절장애가 한단계 더 발전하여 이와 연관된 근육이나 인대의 긴장수축이 오랜 시간 진행되어, 이들이 다시 상부 경추의 아탈구와 두개골의 비정상적 움직임에까지 영향을 미쳐 나타나는 것으로 생각된다. 그렇게 되면 뇌에서 필요 충분한 뇌혈액공급이나 뇌척수액순환의 문제를 일으킬 수 있기 때문이다. 그리고 제1형 만성 턱관절장애의 경우는 제2형 급성 턱관절장애가 좀 더 진행되면서 척추 및 근골격계의 구조변화, 교합 및 턱의 구조변화 그리고 안면구조의 변화에 이르기까지 점점 진행되어 나타나는 것으로 보인다. 따라서 각종 척추 디스크질환, 관절질환을 비롯해서 두개천골계의 순환문제, 부정교합 및 턱 비대칭, 안면 비대칭의 문제를 유발하게 된다고 추정된다. 그러나 두번째 유형의 만성 턱관절장애는, 턱에서 지속적이고 반복적인 그리고 과다한 부정적 자극들이 오랜 기간 누적되면서 턱에 분포된 C 섬유를 비롯한 3차신경의 가소성변화를 유발하면서 결국 중추신경계를 포함하여 전체신경계의 회로망에까지 파급되어 다양한 만성질환 또는 난치성 질환들이 양산되는 것으로 추정하고 있다. 아마도 지금까지 서양의학에서 아직 밝혀내지 못한 대부분의 질병들이 여기에 포함되지 않을까 하는 것이 나의 생각이다.

Diagnosis of Coronary Artery Disease using Myocardial Perfusion SPECT in Patients with Diabetes Mellitus: Analysis of Risk Factors (당뇨병 환자에서 심근관류 SPECT을 이용한 관동맥질환의 진단: 위험인자 분석)

  • Seo, Ji-Hyoung;Kang, Seong-Min;Bae, Jin-Ho;Jeong, Shin-Young;Lee, Sang-Woo;Yoo, Jeong-Soo;Ahn, Byeong-Cheol;Lee, Jae-Tae
    • Nuclear Medicine and Molecular Imaging
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    • v.40 no.3
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    • pp.155-162
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    • 2006
  • Purpose: Diabetes mellitus (DM) is a critical disease with higher rates of cardiovascular morbidity and mortality due to myocardial ischemia and infarction. There is glowing interest in how to determine high-risk patients who are candidates for screening testing. This study was performed to evaluate the incidence of coronary artery disease (CAD) in diabetic patients detected by Tc-99m MIBI myocardial perfusion SPECT (MPS) and to assess risk factors of CAD and cardiac hard events. Subjects and Methods: 203 diabetic patients (64 male, mean age $64.1{\pm}9.0$ years) who underwent MPS were included between Jan 2000 and July 2004. Cardiac death and nonfatal myocardial infarction (MI) were considered as hard events, and coronary angioplasty and bypass surgery >60 days after testing were considered as soft events. The mean follow-up period was $36{\pm}18$ months. Patients underwent exercise (n=6) or adenosine stress (n=197) myocardial perfusion SPECT. Results: Perfusion defects on MPS were detected in 28.6% (58/203) of the patients. There was no cardiac death but 11 hard events were observed. The annual cardiac hard event rate was 1.1%. In univariate analysis of clinical factors, typical anginal pain, peripheral vascular disease, peripheral polyneuropathy, and resting ECG abnormality were significantly associated with the ocurrence of hard events. Anginal pain, peripheral vascular disease, and resting ECG abnormality remained independent predictors of nonfatal MIs with multivariate analysis. Abnormal SPECT results were significantly associated with high prevalence of hard events but not independent predictors on uni- and multivariate analyses. Conclusion: Patients who were male, had longer diabetes duration (especially over 20 years), peripheral vascular disease, peripheral polyneuropathy, or resting ECG abnormality had higher incidence of CAD. Among clinical factors in diabetic patients, typical angina, peripheral vascular disease, peripheral polyneuropathy, and resting ECG abnormality were strong predictors of hard events.

Convergent Relationship between Job Stress and Oral Subject Symptoms in Office Workers (직장인의 직무 스트레스와 구강 자각증상의 융합적 관련성)

  • Heo, Seong-Eun
    • Journal of Convergence for Information Technology
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    • v.10 no.4
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    • pp.140-150
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    • 2020
  • This study was conducted to investigate the effect of job stress on oral subjective symptoms observed in office workers. A survey of office workers in the Gyeonggi-do area was conducted and data collected was analyzed using SPSS 21.0 program. The results showed that among the sub-scales of job stress, job insecurity, job demand, and positive organizational system had significant effects on dysmasesis (p<.01), gum bleeding and gum disease (p<.01), and halitosis (p<.05) as well as gum disease (p<.01), respectively. Therefore, it is considered that making an effective job stress management plan and predicting related oral subjective symptoms in office workers will help improve the oral health management of office workers and adult oral health management in general.

플라즈마를 이용한 Toilet 오염 방지 표면 처리 기술의 개발 -I. 오염 현상의 정량적 평가-

  • Do, U-Ri;Yang, Won-Gyun;Ju, Jeong-Hun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.401-401
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    • 2010
  • 현대사회로 들어오면서 과거와 달리 외부에 있던 화장실이 내부로 들어오면서 변기 뚜껑을 닫지 않고 toilet flushing을 할 때 배변에 포함된 다량의 장티푸스, 포도상 구균 같은 종류의 세균이 화장실 곳곳에 퍼짐에 의하여 면역력이 약한 경우 여러 가지 세균성 질환 및 2차 감염을 통하여 장티푸스 및 피부 질환 등이 발생한다. 본 연구에서는 이런 감염을 최소화하기 위한 방법으로 플라즈마를 이용한 세변기 표면의 오염 방지처리 기술을 개발하는 것을 목표로 한다. 일차적으로 여러 가지 운용 조건에서 오염의 정도를 파악하고자 배변의 양에 따라 toilet flushing 시 피부 오염의 물질 노출 정도를 평가 하였다. 실험 방법은 배변을 모사하여 toilet system에 넣고 물을 내려 무게에 따른 물 튀김 정도와 위치 분포를 분석하였다. 밀가루 반죽의 무게가 증가하면서 피부에 닿는 물 튀김 면적이 특정 무게에서 최대 60.02 mm2까지 증가하다 감소했다. 또한 실제 측정 결과를 통하여 물 튀김의 분포가 뒤쪽에 집중되는 것을 볼 수 있었다. 이와 같이 실제 toilet flushing시 세균에 의하여 피부 오염 및 국부 감염이 발생할 수 있다는 것을 확인할 수 있었다. 또한 비데 동작 시 변기 내부에 잔존하는 세균 자체가 확산되는 정도를 3차원 유체 역학 모델링으로 예측하였다. 앞으로 세변기 뚜껑의 플라즈마 표면처리 및 toilet flushing 유로 디자인 개선을 통해 세균의 잔류 및 퍼짐을 최소화함으로써 최종적으로 세균성 질환을 줄일 수 있는 방법을 개발하는 것이 본 연구의 1단계 목표다.

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Ai-Based Cataract Detection Platform Develop (인공지능 기반의 백내장 검출 플랫폼 개발)

  • Park, Doyoung;Kim, Baek-Ki
    • Journal of Platform Technology
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    • v.10 no.1
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    • pp.20-28
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    • 2022
  • Artificial intelligence-based health data verification has become an essential element not only to help clinical research, but also to develop new treatments. Since the US Food and Drug Administration (FDA) approved the marketing of medical devices that detect mild abnormal diabetic retinopathy in adult diabetic patients using artificial intelligence in the field of medical diagnosis, tests using artificial intelligence have been increasing. In this study, an artificial intelligence model based on image classification was created using a Teachable Machine supported by Google, and a predictive model was completed through learning. This not only facilitates the early detection of cataracts among eye diseases occurring among patients with chronic diseases, but also serves as basic research for developing a digital personal health healthcare app for eye disease prevention as a healthcare program for eye health.

The Development of Convergence Optimized LOS Management System (융복합 맞춤형 재원일수 관리 시스템 개발)

  • Choi, Youn-Hee;Kim, Yun-Jin
    • Journal of Digital Convergence
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    • v.15 no.2
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    • pp.273-283
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    • 2017
  • This study aims to develop a convergence optimized LOS(Length of Stay) management system that can provide efficient by predicting LOS on outpatient information for inducing the LOS to manage their own activities. web program has been implemented to comput in real-time predicting LOS by using the predicted LOS model of outpatient information. The predict model was derived management targets of long term predicted patient group and intensive care patient group. The optimized LOS(Length of Stay) management system was confirmed efficient for optimizing management of LOS that can provide by the long-term predicting alarm and over LOS alarm service for long term predicted patient group and intensive care patient group. Therefore the trial operating policy alternative on extension of predicted LOS is needed to utilized convergence optimizing system on LOS.

Factors which Differentiate Ex-smokers from Smokers among Patients with Cardiovascular Disease (심혈관계 질환자의 금연성공 예측 요인)

  • Choi, Jung-Myung;Kim, Eun-Kyung
    • The Journal of Korean Academic Society of Nursing Education
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    • v.11 no.2
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    • pp.177-183
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    • 2005
  • Purpose: The purpose of this study was to identify factors which differentiate ex-smokers from smokers among patients with cardiovascular disease. Ex-smokers were patients who abstained from smoking for at least 6 months. Method: The subjects were 92 male cardiovascular patients who try to quit. The stepwise discriminant analysis was used to identify predictors of smoking cessation. Result: 1. The ex-smokers(n=47) and smokers(n=45) were significantly different regarding the age, duration after diagnosis, nicotine dependence, family support for smoking cessation, and intention-to-quit. 2. The family support for smoking cessation, intention-to-quit, nicotine dependence, and age were the predictors which differentiate ex-smokers from smokers among cardiovascular patients. The percentage of grouped cases correctly classified was 92.4%. Conclusion: The higher the family support for smoking cessation, intention-to-quit, age and the lower the nicotine dependence, the more likely these smokers were to success smoking cessation.

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Detection of SNPs involved in the development of complex diseases with the boolean algebra (부울 대수를 이용한 복합질환의 중요 SNP 찾기)

  • Sangseob Leem;SeunghyunKim;Kyubum Wee
    • Proceedings of the Korea Information Processing Society Conference
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    • 2008.11a
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    • pp.722-725
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    • 2008
  • 복합질환(complex disease)의 원인과 작용 모델을 찾기 위해 여러 가지 통계적인 방법들과 기계 학습(machine learning)의 방법 등이 사용되고 있다. 소수 SNP의 작용모델을 찾는 방법은 많이 알려져 있지만 다수 SNP의 작용 모델을 효과적으로 찾는 방법은 거의 연구되어 있지 않다. 본 연구에서는 원인 SNP들의 작용을 부울 식(boolean expression)으로 나타내고, 유전 알고리즘(genetic algorithm)을 이용하여 예측 정확도가 높은 부울 식을 구성하였으며 실제 자료와 생성된 자료에 대하여 제안한 모델의 성능을 측정하였다.

Comparison of Vessel Disease and Gensini Score according to Ankle-Brachial Index in Patients with Cardiovascular Disease (심혈관 질환자의 발목-상완 지수에 따른 Vessel disease 및 Gensini score 비교 융복합 연구)

  • Choi, Suk-Kyeong;Choi, Hye-Ran
    • Journal of Digital Convergence
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    • v.15 no.1
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    • pp.267-275
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    • 2017
  • The purpose of this study was to evaluate the clinical availability of ankle-brachial index(ABI) according to severity of cardiovascular disease. The subjects of this study were the patients who had ABI in a general hospital. In this study, total 441 patients were enrolled for analysis. Electric medical records were reviewed to investigate the result of ABI and severity of cardiovascular disease measured vessel disease and Gensini score. Collected data were analyzed using SPSS 21.0 program. Subjects with $ABI{\leq}0.90$ and > 0.90 were classified as having abnormal and normal ABI. There were significant differences in vessel disease categorization($x^2=4.731$, p=.030) and Gensini score(t=2.351, p=.019) between two groups. Therefore, ABI is an effective and non-invasive tool for the diagnosis of cardiovascular disease with high severity. ABI is a valuable predictive index of ischemic heart disease.

The Study on Risk Factor of Metabolic Diseases in Pancreatic Steatosis (췌장지방증에서 대사성질환의 위험 요인에 관한 연구)

  • Cho, Jin-Young;Ye, Soo-Young;Kim, Dong-Hyun
    • Journal of radiological science and technology
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    • v.39 no.1
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    • pp.81-88
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    • 2016
  • The body of the fat tissue increased in obese represented by risk factors such as cardiovascular diseases, diabetes, metabolic disease and dyslipidemia. Such metabolic diseases and the like of the cardiovascular and cerebrovascular disease, hypertension, dyslipidemia, increase in the adipose tissue of the pancreas is known to be a risk factor of these diseases. Study on the diagnosis and treatment of pancreatic cancer was conducted actively, case studies on pancreatic steatosis is not much. In this study, divided into a control group diagnosed with pancreatic steatosis as a result of ultrasonography to evaluation the physical characteristics and serologic tests and blood pressure and arterial stiffness. The control group and the test pancreas steatosis age and waist circumference, body mass index, total cholesterol, HDL cholesterol, LDL cholesterol, and systolic and diastolic blood pressure, fasting blood glucose, arterial elasticity is higher in pancreatic steatosis. And the lower ankle brachial stenosis and HDL-cholesterol were lower than the normal control group, so the pancreatic steatosis harmful to blood vessels.(P <0.05). The difference between the control group and it was confirmed that the pancreatic jibanggun statistically significant. In conclusion, pancreatic steatosis at abdominal ultrasound can predict the risk of metabolic diseases, and there was a correlation with cardiovascular disease.