• The Korean Journal of Applied Statistics
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• v.22 no.2
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• pp.329-340
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• 2009

For complex diseases such as diabetes, hypertension, it is believed that model-free methods might work better because they do not require a precise knowledge of the mode of inheritance controlling the disease trait. This is done by estimating the sharing probabilities that a pair shares zero, one, or two alleles identical by descent(IBD) and has some specific branches of test procedure, i.e., the mean test, the proportion test, and the minmax test. Among them, the minmax test is known to be more robust than others regardless of genetic mode of inheritance in current use. In this study, we compared the power of the methods which are based on minmax test and considering weighting schemes for sib-pairs to analyze sibship data. In simulation result, we found that the method based on Suarez' was more powerful than any others without respect to marker allele frequency, genetic mode of inheritance, sibship size. Also, The power of both Suarez- and Hodge-based methods was higher when marker allele frequency and sibship size were higher, and this result was remarkable in dominant mode of inheritance especially.

• The Journal of the Korea Contents Association
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• v.17 no.7
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• pp.696-706
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• 2017

This study is to examine health care utilization and morbidity of disabled and non-disabled children in Korea to evaluate the health disparities. We used medical claim data of 2010 from the National Health Insurance Service-National Sample Cohort data. As a result of the analysis, the disabled children are not in good health condition because they have more frequency of medical service use, hospitalization rate, and more number of diseases and spent more on medical expenses than non-disabled children. Patterns of the most frequent disease differ from significantly between disable and non-disabled. Disabled children had a higher prevalence of selected birth defects and selected health conditions associated with physical disability and a lower prevalence of selected infection disease than children without disability. In conclusion, Health policy changes that would extend the access to health service for children with disabilities characterized by frequent medical care, hospitalization, excessive medical expenditure and complex diseases.

• The Korean Journal of Applied Statistics
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• v.31 no.4
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• pp.529-538
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• 2018

Tuberculosis causes high morbidity and mortality. However, Korea still has the highest tuberculosis (TB) incidence and mortality among OECD countries despite decreasing incidence and mortality due to the development of modern medicine. Korea has now implemented various policy projects to prevent and control tuberculosis. This study analyzes the effects of public-private mix (PPM) tuberculosis control program on treatment outcomes and identifies the factors that affecting the success of TB treatment. We analyzed 130,000 new tuberculosis patient cohort from 2012 to 2015 using data of tuberculosis patient reports managed by the Disease Control Headquarters. A cumulative incidence function (CIF) compared the cumulative treatment success rates for each factor. We compared the results of the analysis using two popular types of competition risk models (cause-specific Cox's proportional hazards model and subdistribution hazard model) that account for the main event of interest (treatment success) and competing events (death).

• Journal of Oral Medicine and Pain
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• v.37 no.3
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• pp.135-139
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• 2012

Hereditary hemorrhagic telangiectasia is a rare autosomal dorminant disease that features abnormal and fragile vascular dilations of terminal vessels in skin and mucous membranes, as well as arteriovenous malformations of internal organs, particularly lungs, brain, and liver. Often patients have not been diagnosed with HHT for a long time, and undiagnosed HHT patients unnecessarily develop serious complications such as severe life-threatening hemorrhage, stroke or brain abscess. Therefore, early detection and appropriate screening is very important. Early detection of HHT allows the appropriate screening for the presence of silent disease such as AVMs in the lungs, liver, or brain, and preventive treatment in the patient and their affected family members. Dentists should be familiar with HHT because the telangiectases on skin and oral mucosa are often the most dramatic and most easily identified component of HHT. Recently, we experienced a case of HHT. We present the case with a review of the literature.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.447-454
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• 2019

The purpose of this study aims to be used as base data of a policy which forms university students' appropriate behavior for the prevention of infection by analyzing some university students' prevention awareness of new type of infection. A self-administered questionnaire survey about students' seriousness, sensitivity, self-efficacy, and prevention behavior intent of new infection, was conducted in an university located in Gyeonbuk from April. 30th to May. 11th, 2018. Analyzing factors which affect the prevention behavior intent of infection with controlled general factor and health behavior, the prevention behavior intent was increased by ${\beta}=.125$ as seriousness increases and ${\beta}=.709$ as self-efficacy increases in Model 2, final model. However, sensitivity has no significant effect on the prevention behavior intent. Originally sensitivity has to be a significant factor regarding to the prevention behavior intent of new infection. But the result that sensitivity has no influence at all, shows that the students are insensitive to new diseases as they don't fear or sense danger of new infection. Therefore, a disease control policy which helps to increase sensitivity has to be established.

• The Journal of the Korea Contents Association
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• v.22 no.2
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• pp.420-430
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• 2022

The study attempted a comprehensive assessment of factors affecting health-related quality of life in the young-old and old-old. Data from the Community Health Survey for 5 years from 2015 to 2019 were analyzed. Research Results Health-related quality of life appears to be higher in the elderly than in the late-stage elderly, and various factors such as age, education level, household income, presence or absence of economic activity, presence or absence of moderate physical activity, stress or presence, and subjective health level Has been found to affect health-related quality of life. In particular, good or bad subjective health and subjective oral health had the greatest influence. In terms of the household type, the quality of life was high in young-old adults living in a three-generation household and old-old adults living in a one-generation household. Considering these characteristics, public policy programs should be developed and implemented to help the elderly with successful aging by improving their quality of life.

• Pediatric Infection and Vaccine
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• v.29 no.2
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• pp.110-117
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• 2022

Herpes zoster (HZ) has been reported in immunocompetent children who received the varicella vaccine. In vaccinated children, HZ can be caused by vaccine-strain or by wild-type varicella-zoster virus (VZV). Like wild-type VZV, varicella vaccine virus can establish latency and reactivate as HZ. We report two cases of HZ in otherwise healthy 16- and 14-month-old boys who received varicella vaccine at 12 months of age. They presented with a vesicular rash on their upper extremities three to four months after varicella vaccination. In one case, a swab was obtained by abrading skin vesicles and VZV was detected in skin specimens by polymerase chain reaction. The VZV open-reading frame 62 was sequenced and single nucleotide polymorphism analysis confirmed that the virus from skin specimen was vaccine-strain. This is the first HZ case following varicella vaccination confirmed to be caused by vaccine-strain VZV in the immunocompetent children in Korea. Pediatricians should be aware of the potential for varicella vaccine virus reactivation in vaccinated young children.

• Proceedings of the Safety Management and Science Conference
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• 2006.04a
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• pp.195-200
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• 2006

건설업계는 제조업과 특성이 달라 여러 가지 문제점이 엿보인다. 특히, 건설업 근골격계 질환에 대한 연구 및 지원은 별로 찾아볼 수가 없다. 근골격계 질환의 제조업과 건설업의 비율을 보았을 때 "2004 산업재해분석" 요양자 업종별 분포를 보면 제조업이 3,281명(79.79%)로 건설업의 63명(1.53%)보다 월등히 많은 것으로 조사되었다. 이는 미국의 사례를 보았을 때, 2007년 업종별 분포를 보면 건설업이 42,867명(26.20%), 제조업이 101,437명(36.23%)로 우리나라에 비해 건설업 근골격계 질환자가 상대적으로 많은 것으로 조사되었다. 이는 건설업에서의 근골격계 부담 작업 실태조사 등을 통하면 제도적 문제점이나, 근로자가 몰라서 질병에 이환되는 경우가 아닌가 한다. 건설업 근로자들은 건설업 특성상 근골격계 질환예방을 위한 도구를 거의 사용하지 못하고, 작업의 연속성, 지속성이 떨어지므로 부자연스럽고, 불편한 자세를 작업을 위해 수시로 반복하여 취할 수 밖에 없다. 따라서 건설업체에 중대재해를 줄이기 위한 노력 뿐 만 아니라, 열악한 건설업체의 근로자의 근골격계 질환 예방에 대한 제도적인 지원과 안전담당자 교육, 근로자에 대한 근골격계 질환 예방교육(스트레칭, 작업 자세, 동작, 근력강화, 적절한 휴식시간 부여) 등 대책이 절실히 필요하고 하겠다.

• The Journal of Korean Society for School & Community Health Education
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• v.11 no.1
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• pp.57-66
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• 2010

Objectives: The purpose of this study was to examine health behavior and disease of children and adolescents. Method: Data was taken from the Korean National Health and Nutrition Examination Survey. The SPSS 12.0 program was used for statistical analysis of data collected. Results: For the past one year, 57% of study group had oral examinations, 43.9% of them were vaccinated against influenza, and 16.9% tried to control body weight. Many children and adolescents (37.7%) had diseases, and 16% were diagnosed chicken pox. Of the subjects who were over 10 years old 35.9% had low high density lipid. The difference of sickness status between children and adolescents was significant ($x^2$=8.376, P=.015). The differences between children and adolescents in subjective health status, oral examination, vaccination of influenza, subjective physical change, body weight change and weight control efforts in the past one year were significant. The differences between children and adolescents in diagnosis of sinusitis, pneumonia and low HDL were statistically significant. Conclusions: The children and adolescents have different characters in health perimeters and these factors should be considered in order to improve the health status of children and adolescents.

• The Korean Journal of Pain
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• v.3 no.2
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• pp.131-138
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• 1990

Postherpetic neuralgia (PHN) causes intractable pain which disturbs sleep and daily life. Numerous drugs and treatment strategies have been introduced for the management of PHN. However, no single regimen has proved to be effective. I analysed 38 patients with PHN. Amitriptyline, a tricyclic antidepressant and chlorpromazine were most commonly prescribed. Stellate ganglion blocks for the head and neck pain and epidural blocks for the rest part of the body were most frequently given. Triamcinolone acetate was administered epidurally in most of the cases or by iontophoresis on the affected skin area in two cases. Complications were related to the technique of the nerve block and the side effects of drugs administered. Repeated nerve blocks with tricyclic antidepressant and steroid therapy were thought to be the most effective for the treatment of postherpetic pain.