• Title/Summary/Keyword: 진단 지연

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A Clinical Study of Congenital Intrahepatic Portosystemic Shunt Diagnosed in Neonatal Period (신생아기에 진단된 선천성 간내 문맥 전신성 단락의 임상적 고찰과 치료)

  • Kim, Ji-Young;Kim, Kyung-A;Lee, Yeon-Kyung;Ko, Sun-Young;Shin, Son-Moon;Han, Byung-Hee
    • Neonatal Medicine
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    • v.18 no.1
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    • pp.117-123
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    • 2011
  • Purpose: Congenital intrahepatic portosystemic shunts are rare disease and clinically asymptomatic shunts may be detected by chance on ultrasonogram before and after birth. We studied clinical course, treatment and prognosis of congenital intrahepatic portosystemic shunt at prenatal or neonatal period. Methods: Medical records of 8 patients which were diagnosed in intrahepatic portosystemic shunt in Cheil General Hospital from 2006 through 2010 were reviewed retrospectively. Results: Eight patients with congenital intrahepatic portosystemic shunts were identified. Six patients were diagnosed at prenatal radiological screening, including three cases of intrauterine growth restriction and two cases of preterm baby. One case with increased serum ammonia underwent coil embolization. In four cases including one case that presented elevated direct bilirubin, shunts were closed spontaneously within 11th month after birth. Two patients were diagnosed on abdominal sonogram after birth because of elevated direct hyperbilirubinemia, all of whom presented intrauterine growth restriction. Closure of shunts was confirmed during 4th month to 6th month. Conclusion: Congenital intrahepatic portosystemic shunts are clinically asymptomatic mostly and spontaneous closure is expected within 2 years age. But occasionally they have severe complication, so clinical and radiological observation is needed. Specially in cases of intrauterine growth retardation without evident cause, the possible diagnosis of congenital intrahepatic portosystemic shunts should be considered and prenatal and postnatal examination should be performed. When prenatal diagnosis is made, fetal wellbeing should be monitored periodically until spontaneous closure of shunts.

Computer-Aided Diagnosis Parameters of Invasive Carcinoma of No Special Type on 3T MRI: Correlation with Pathologic Immunohistochemical Markers (3T 자기공명영상에서 비특이 침윤성 유방암의 컴퓨터보조진단 인자들과 병리적 면역조직화학 표지자들과의 상관성)

  • Jinho Jeong;Chang Suk Park;Jung Whee Lee;Kijun Kim;Hyeon Sook Kim;Sun-Young Jun;Se-Jeong Oh
    • Journal of the Korean Society of Radiology
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    • v.83 no.1
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    • pp.149-161
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    • 2022
  • Purpose To investigate the correlation between computer-aided diagnosis (CAD) parameters in 3-tesla (T) MRI and pathologic immunohistochemical (IHC) markers in invasive carcinoma of no special type (NST). Materials and Methods A total of 94 female who were diagnosed with NST carcinoma and underwent 3T MRI using CAD, from January 2018 to April 2019, were included. The relationship between angiovolume, curve peak, and early and late profiles of dynamic enhancement from CAD with pathologic IHC markers and molecular subtypes were retrospectively investigated using Dwass, Steel, Critchlow-Fligner multiple comparison analysis, and univariate binary logistic regression analysis. Results In NST carcinoma, a higher angiovolume was observed in tumors of higher nuclear and histologic grades and in lymph node (LN) (+), estrogen receptor (ER) (-), progesterone receptor (PR) (-), human epidermal growth factor 2 (HER2) (+), and Ki-67 (+) tumors. A high rate of delayed washout and a low rate of delayed persistence were observed in Ki-67 (+) tumors. In the binary logistic regression analysis of NST carcinoma, a high angiovolume was significantly associated with a high nuclear and histologic grade, LN (+), ER (-), PR (-), HER2 (+) status, and non-luminal subtypes. A high rate of washout and a low rate of persistence were also significantly correlated with the Ki-67 (+) status. Conclusion Angiovolume and delayed washout/persistent rate from CAD parameters in contrast enhanced breast MRI correlated with predictive IHC markers. These results suggest that CAD parameters could be used as clinical prognostic, predictive factors.

Clinical Analysis of Intussusception Delayed in the Final Diagnosis (발병 초기에 진단하지 못한 장중첩증에 관한 고찰)

  • Kim, Eo Jin;Lee, Min Hae;Lee, Hae Young;Kim, Jum Su;Seo, Ji Hyun;Lim, Jae Young;Choi, Myoung Bum;Park, Chan Hoo;Woo, Hyang Ok;Youn, Hee Shang
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.7 no.1
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    • pp.16-23
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    • 2004
  • Purpose: In this study, we tried to evaluate the clinical characteristics or circumstances that lead to unintentionally the delay in the diagnosis of intussusception or to the wrong direction that prevent the proper management early. Methods: All the patients of intussusception with delayed diagnosis in the department of pediatrics or emergency room at Gyeongsang National University Hospital from 1990 to 2003 were enrolled and reviewed retrospectively. Results: There were 8 boys and 6 girls and their median age was 8 months (range 2 months to 10 years). Their initial symptoms and signs were vomiting, seizure, diarrhea, lethargy, irritability, bloody stool, palpable abdominal mass, foul odor of urine and tachycardia. Clinical diagnosis or impressions at admission consisted of acute gastroenteritis, shigellosis and toxic encephalopathy, convulsive disorders, urinary tract infections, sepsis, abdominal mass and intestinal obstruction. Eight patients were luckily diagnosed due to the delayed manifestations of cyclic irritability or currant jelly stool. Six patients were not paid attentions for the possibilities of intussusception and diagnosed serendipitiously by the abdominal sonography or CT during the evaluation of the abdominal mass or distension. Only five of 14 cases (35.7%) were successfully managed by barium or air reductions. The other 9 cases needed surgical operations. Conclusion: Delayed diagnosis of intussusception arise when doctors initially diagnose the patients incorrectly due to the unusual presentations or when they overlook the newly arising symptoms or signs suggestive intussusception after the admission because they are ardently attached to the first impressions or initial clinical diagnosis.

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Saliva: Diagnostic Applications in Medicine and Dentistry (임상에서 타액의 진단적 응용을 위한 고찰)

  • Kim, Jiyeon;Jeong, Taesung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.42 no.1
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    • pp.102-111
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    • 2015
  • Due to the rapid advancements in detection technologies, saliva has the potential to become a first-line diagnostic sample of choice in the fields of medicine and dentistry. Saliva has many useful advantages to serum. Simple, non-invasive and cost-effective approaches can be made possible for the screening of large populations. There is minimal risk of infections during sample collection and saliva can be used in clinically challenging situations, such as obtaining samples from children, or disabled or anxious patients. This review examines the diagnostic application of saliva and provides a summary of recent research advancement.

Diagnosis of Hepatic Hemangioma by $^{99m}Tc-RBC$ Scintigraphy ($^{99m}Tc-RBC$ 간신티그램에 의한 간혈관종의 진단)

  • Chung, Soo-Kyo;Son, Hyung-Sun;Lee, Myung-Hee;Shinn, Kyung-Sub;Bahk, Yong-Whee
    • The Korean Journal of Nuclear Medicine
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    • v.19 no.2
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    • pp.97-99
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    • 1985
  • 간혈관종은 가장 흔한 양성 간종양이다. 그러나 혈관종의 감별진단은 용이하지 않다. 근래에 간현관종의 진만에 $^{99m}Tc-RBC$를 이용한 간신티그램이 많이 이용되고 있다. 저자들은 $^{99m}Tc-RBC$를 사용하는 간신티그램을 시행하여 (1) 간혈관 신티그램상 혈류 증가에 의한 냉소변연부의 방사능 섭취 증가를 동맥기에서 관찰할 수 있었고, (2) 시간 경과에 따라 방사능 집적이 냉소의 변연부에서부터 차츰 중앙으로 진행되어 마침내, (3) 지연 촬영 영상에서는 냉소가 완전히 열소로 변하는 것을 확인함으로써, 간혈관종을 진단할 수 있었기에 문헌고찰과 함계 보고하는 바이다.

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A Case of Sandifer Syndrome (Sandifer 증후군 1례)

  • Lee, Mira;Kim, Soo Hyun;Kim, Yong Joo;Seol, In Joon
    • Clinical and Experimental Pediatrics
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    • v.46 no.10
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    • pp.1036-1039
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    • 2003
  • Sandifer syndrome is a rare manifestation of gastroesophageal reflux in children, occurring in association with abnormal movement of the head and neck and recurrent episodes of seizure after feeding. This syndrome may be misdiagnosed as infantile seizure and musculoskeletal disorder and may be associated with failure to thrive, anemia, aspiration pneumonia, and esophagitis. In this paper, Sandifer syndrome in a four months old male with recurrent aspiration pneumonia, apnea, and seizure after feeding is presented.

Fault Diagnosis in Power Systems using the Time Sequence Information of Protection System (전력계통 사고시 보호 시스템의 순차정보를 이용한 고장진단법)

  • 노명균;홍상은
    • Proceedings of the KAIS Fall Conference
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    • 2003.06a
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    • pp.193-195
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    • 2003
  • 최근 산업의 핵심 에너지원을 공급하고 있는 전력회사의 운영에서, 계통 사고시 대량의 경보 신호 발생으로 인하여 운전원의 혼란을 가져오게 되어, 사고후 복구시간의 지연을 초래하는 문제로 인한 해당산업체의 손실이 대형화하는 추세이다. 본 논문에서는 이와 같은 문제를 해결하는 방안으로 사고시 보호시스템의 순차정보를 이용하여 단시간에 고장진단을 수행함으로서, 고장의 원인 파악과 정확한 고장발생지점 정보를 운전원에게 제공할 수 있는 방법을 제안하고 있다. 고장진단 기법은 고장 발생의 불확실성을 고려한 보호시스템의 모델링 방법과 퍼지 페트리네트 기법을 개발하여 적용하였다. 본 연구에서 개발한 방법을 사례연구를 통하여 모델 계통에 적응하고 그 유효성 여부를 확인한 결과 만족할 만한 성과를 얻을 수 있었다. 특히 보호시스템의 오동작이나 부동작 둥의 불확실한 정보를 처리하는 데 본 연구에서 개발한 퍼지 페트리네트 기법이 탁월한 성능을 발휘하므로 실제의 대형 전력계통에 적용 가능성을 확인할 수 있었다. 또한 본 방법은 SCADA로부터 전송되는 실시간 데이터의 온라인 처리도 가능하므로 그 유용성은 아주 높다고 볼 수 있다.

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A Distributed Real-time Self-Diagnosis System for Processing Large Amounts of Log Data (대용량 로그 데이터 처리를 위한 분산 실시간 자가 진단 시스템)

  • Son, Siwoon;Kim, Dasol;Moon, Yang-Sae;Choi, Hyung-Jin
    • Database Research
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    • v.34 no.3
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    • pp.58-68
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    • 2018
  • Distributed computing helps to efficiently store and process large data on a cluster of multiple machines. The performance of distributed computing is greatly influenced depending on the state of the servers constituting the distributed system. In this paper, we propose a self-diagnosis system that collects log data in a distributed system, detects anomalies and visualizes the results in real time. First, we divide the self-diagnosis process into five stages: collecting, delivering, analyzing, storing, and visualizing stages. Next, we design a real-time self-diagnosis system that meets the goals of real-time, scalability, and high availability. The proposed system is based on Apache Flume, Apache Kafka, and Apache Storm, which are representative real-time distributed techniques. In addition, we use simple but effective moving average and 3-sigma based anomaly detection technique to minimize the delay of log data processing during the self-diagnosis process. Through the results of this paper, we can construct a distributed real-time self-diagnosis solution that can diagnose server status in real time in a complicated distributed system.

Egress Safety of Nursing Hospital Considering Egress Guides and Smoke Exhaust System (피난유도자 수와 배연설비를 고려한 요양병원의 피난안전성 평가)

  • Choi, Seung-Ho;Darkhanbat, Khaliunaa;Heo, Inwook;Kim, Kang Su
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.3
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    • pp.64-71
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    • 2022
  • In this study, fire and egress simulation was conducted for the egress safety evaluation of the nursing hospitals. A fire simulation was performed with or without the smoke exhaust system using the FDS, and the available safe egress time (ASET) of the nursing hospitals was calculated. In addition, an egress simulation considering the characteristics of occupants and egress delay time was performed using Pathfinder, and the required safe egress time (RSET) was calculated. By comparing the ASET and RSET, the egress safety of the nursing hospital with or without a smoke exhaust system was evaluated according to the number of egress guides and the egress delay time. The simulation results show that the number of casualties increased as the egress delay time increased, and the required safe egress time decreased as the number of egress guides increased. In addition, it was found that if a smoke exhaust system with the capacity specified in the KFPA is secured, the available safe egress time can be greatly increased and the number of casualties can be greatly reduced.