• Journal of Life Science
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• v.19 no.5
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• pp.664-670
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• 2009

The ${\beta}$3-adrenergic receptor (ADRB3) is expressed mainly in visceral adipose tissue and is thought to contribute to lipolysis and the delivery of free fatty acids to the portal vein. This study was aimed at evaluating the association between high-density lipoprotein cholesterol (HDL-C) and ADRB3 genetic polymophisms. A total of 991 healthy examinees who were examined in a university hospital, located in Busan City, between May and December 2006 were enrolled in this study. Height, weight, body mass index, waist circumference, and systolic and diastolic blood pressures of the subjects were examined. Intravenous concentrations of fasting blood glucose, total cholesterol, HDL-C, low-density lipoprotein cholesterol, and triglyceride were also measured. After extracting DNA from the subjects, mutations of the +188T>C (Trp64Arg) of exon 1 and +3893T>C of intron 2 on the ADRB3 gene were genotyped using the single base extension method. We have identified a novel mutation of ADRB3 that is located in intron 2. The frequency of its minor allele was 0.164. Both the +188T>C mutation of exon 1 and +3893T>C mutation of intron 2 were significantly associated with HDL-C. The mean concentration of serum HDL-C was significantly lower in the presence of their minor allele 'C'. These results suggest that both mutations of +188T>C of exon 1 and +3895T>C of intron 2 have significant associations with HDL-C in the Korean population.

• Journal of Korean Society of Forest Science
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• v.105 no.4
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• pp.422-428
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• 2016

Ginkgo (Ginkgo biloba L.) is one of the most appropriate roadside trees because of a good transplantation nature and ability to grow well in urban environment. Ginkgo is a dioecious species. Sex discrimination of ginkgo is possible through comparing morphological characters of reproductive organs. However, it needs more than about twenty years for reproductive organs to appear after sexual maturity. Until now, ginkgo trees for roadside plantation have been planted without discriminating the sex because ginkgo trees have been usually planted before sexual maturity. Ginkgo nuts from the female ginkgo trees planted along the roadside emit a foul odor, and make much pollution on the streets. Thus in this study a novel SCAR marker (SCAR-GBM) for the early sex discrimination was developed. Primers were developed on the basis of the sequence of male-specific RAPD variants reported previously. False-negative problem of SCAR marker, probably caused by dominant nature, was resolved by using multiplex PCR using primers of both the SCAR-GBM and a universal primer set of atp1 region in mitochondria DNA, which resulted in improved discrimination efficiency. The results showed that DNA bands of 1,039 bp were commonly amplified by the atp1 primer set in male and female trees, and SCAR-GBM markers of 675 bp were specifically amplified only in male trees. Reproducible and specific discrimination of the multiplex PCR was finally confirmed by applying multiple male and female individuals.

• Korean Journal of Environmental Agriculture
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• v.33 no.4
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• pp.290-297
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• 2014

BACKGROUND: The current study purposed to analyse the dissipation levels of a neonicotinoid insecticide and clothianidin in paddy and upland soils and clarify the effects of soil moisture on degradation and persistence of the insecticide. METHODS AND RESULTS: In order to achieve the research purposes, clothianidin 8% SG was applied to the paddy and upland fields at the rate of 0.024 kg a.i./10a, while the analytical standard was treated at 0.25 mg/kg soil under laboratory conditions. Based on the multiple first-order kinetics, total clothianidin in soils was dissipated with $DT_{50}$ of 6.7-16.1 and 6.9-8.2 days in the paddy and upland fields, respectively, whereas the figures under the laboratory condition became larger showing 56.3 and 19.6 days. CONCLUSION: As affected by soil moisture, some differences in degradative pathways were observed. Flooding of soil caused evidently demethylation and delayed cyclization of a major metabolite, thiazolylmethylguanidine (TMG) and methylaminoimidazole(MAI), compared to the aerobic upland condition. More than 80% and 50% of the parent compound was dissipated by the 24th day after the final application in both soils and, transformation products had constituted most of soil residues after that.

• Journal of the Korean Applied Science and Technology
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• v.35 no.3
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• pp.963-974
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• 2018

This study was done to compare cultural competence(CC) and psychological well-being(PWB) in nursing students(NS) and non-nursing students(NNS). Participants were 251 NS and NNS at college in S and I city. Mean score(range:1~5) of CC in NS was 3.35 and NNS, 3.23 and PWB in NS was 3.53 and NNS, 3.37. Thus, mean score of CC and PWB of two group were above the average and NS significantly higher than NNS. Significant relationship were in NS CC, cultural awareness, knowledge, sensitivity, skill and experience, PWB, self-acceptance, environmental mastery, positive relations with others, autonomy, purpose in life, personal growth. Therefore, it is necessary to develop cultural competencies and to provide nursing considering cultural diversity in PWB through extracurricular activities, lectures related to multiple cultures and the placement of multi-cultural subjects in the curriculum.

• Journal of Korean Society of Transportation
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• v.15 no.3
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• pp.75-92
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• 1997

추월가능성을 판단하기 위해서 앞을 바라볼 수 있어야 하는 거리를 추월시거라 한다. 적절한 추원시거의 확보는 2차선 도로의 효율성과 운전자의 안전성 제고 및 도로설계시 매우 중요하다. 이러한 목적을 위하여 추월시거를 산정할 수 있는 여러 모형이 개발되었으나, 실제 교통상황을 반영하기에 많은 문제점을 안고 있음이 지적되고 있다. 따라서 본 논문은 기존 모형들의 이론적 배경을 고찰하고, 각 모형의 단점과 한계를 파악하여, 운전자의 실제 추월형태를 고려한 새로운 추월시거산정모형을 개발하는데 주안점을 두고 있다. 본 논문에서 개발한 PASS모형은 현재 미국에서 도로설계시 기준으로 사용되고 있는 AASHTO모형을 보완하여 구축하였다. 기존의 모형들은 서로 다른 조건을 가정하여 개발되었기 때문에 각 모형들의 추월시거 산정값을 비교분석하는데 어려움이 있다. 하지만 PASS모형은 운전자의 반응시간, 차량의 길이, 차량의 가속능력 등 실제 추월시거 산정시 반드시 고려해야 할 중요한 요소들을 특성치로 반영할 수 있게 함으로써 다양한 추월 상황과 현실적인 교통상황을 폭넓게 수용할 수 있는 장점을 갖고 있다. 본 논문에서는 새로 개발한 P SS모형을 이용하여 얻은 결과와 기존의 AASHTO모형, MUTCD모형, Glennon모형을 통해 얻은 결과를 비교하였으며, PASS모형에 우리나라 현실에 적합한 특성치를 적용하여 2차로 도로의 추월시거를 산정하였다. 이 결과 현재 우리나라 도로용량편람에서 제시하고 있는 추월기능구간 기준인 450m가 설계속도가 낮은 일반국도에는 타당함을 확인할수 있었다. 그러나, 설계속도가 높은 화물타의 운행빈도가 높은 고속국도의 경우, 재검토가 필요할 것으로 판단된다.기존의 광유계 윤활제에 비하여 대단히 고가하는 문제점을 갖고 있다. 그러나 윤활 마찰면의 다양화와 가혹한 사용조건은 자성유체 윤활제의 연구개발 필요성을 크게 증대시키고 있다.xed Effects Model)을 결정하고, 각각에 해당하는 통계모형을 구축하였다. 이 결과 (1) 업종 및 기업규모별로 그룹간에 유의한 특성이 발견되었으며, (2) R&D 및 광고투자는 기업의 시장성과를 설명하는 중요한 변수이나, (3) R&D 투자의 경우는 광고에 비해 불확실성이 존재하는 것으로 나타났고, (4) 수리모형에서 도출된 한계원리가 통계모형에서도 유효한 것으로 드러났다.등을 토대로 한 10대 산업을 육성하기 위하여 과학기술부는 기술수요조사를 바탕으로 49개 주요기술을 도출하여, 과학기술 일류 국가 실현, 국민소득 2만불 달성이라는 국가적 슬로건을 내걸고 “차세대 성장동력” 창출을 위한 범정부차원의 기획과 연구비의 집중투자를 추진하고 있다.달성하기 위해서는 종합류류 전산망의 시급한 구축과 함께 화물차의 적재율을 높이고 공차율을 낮출 수 있는 운송체계의 수립이 필요한 것으로 판단된다. 그라나 이러한 화물전용차선의 효과는 단기적인 치유책일 수밖에 없기 때문에 물류유통 시설의 확충을 위한 사회간접자본의 구축을 서둘러 시행하여야 할 것이다.으로 처리한 Machine oil, Phenthoate EC 및 Trichlorfon WP는 비교적 약효가 낮았다.>$^{\circ}$E/$\leq$30$^{\circ}$NW 단열군이 연구지역 내에서 지하수 유동성이 가장 높은 단열군으로 추정된다. 이러한 사실은 3개 시추공을 대상으로 실시한 시추공 내 물리검층과

• Journal of the Economic Geographical Society of Korea
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• v.16 no.1
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• pp.118-134
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• 2013

This paper analyzes the pubic nature of New Genre Public Arts. It is very sensitive to the social issues and supports democracy and communities with the diverse civic participation. Therefore, it is be widely known without doubt that new genre public arts is more public in nature compared to the previous public arts. This research observes the practices of new genre public art and focuses on the problems of the revealing nature of new genre public art through the analysis of the interrelations among government, artists, and the residents by through observation on the , Seoul City Gallery project from October 2008 to January 2009. The implementation of the project is divided into three constituent parts: local government for funding, artists for planning and implementing, and residents. Local government supports and commands the public art works to create more competitive and harmonious city. Artists emphasize the revitalization of community and take the residents as the passive objects of enlightenment. Whereas, the residents hope to use the funds to improve economic conditions. Artists accept the top-down commands of government, whereas residents tend to passively participate and become objects for enlightenment by artists, after all, might be alienated by the project. These kinds of communications and relationships raise the issue of the possibility of failure of public arts projects.

• Journal of the Korea Society of Computer and Information
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• v.17 no.7
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• pp.129-138
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• 2012

Despite of increasing pressure of opening to free for medical market by an advanced nation and increasing number of portal websites for health information, there have been few studies on the issues of enhancing the service quality of health information websites. The survey exhibited that the quality factors mainly affect significant and satisfied level of health information websites were usability, information structure and contents, interaction, and revisiting. This study was conducted to develop the consumer-focused quality factor of health information websites using WebQual model which was valued at efficient evaluation tool for this information system The methods taken in this research was to survey quality factors for significant and satisfied level of 323 consumers live in Chungcheong-do which is based on 48 questionnaires of WebQual quality factors. Our research extracted quality factors, usability, information quality (information structure and contents), interaction (personalisation and privacy) about view of criticality and satisfaction and relevant degree of revisiting. The research results presented in the paper will provide an efficient way of installing healthcare websites, moreover stone toward a marketing strategy for the consumer focus website provides under fierce competition.

• Proceedings of the KOR-KST Conference
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• 2003.02a
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• pp.3-18
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• 2003

본 논문은 ATMS와 ATIS에서 요구되는 교통관리 및 정보제공의 효과분석을 위해, 운전자의 주행 및 경로선택 의사결정과 교통제어에 대한 반응등 운전자 행태를 모의실험에 반영함으로써 교통시스템의 실시간 특성을 모사할 수 있는 모형을 구축하고 이를 기반으로 하는 미시적 교통 모의실험기를 개발하는 것을 목적으로 하였다. 본 연구에서는 운전자, 차량, 교통망, 검지 및 신호시스템, 교통정보제공시스템 등을 교통시스템의 주요 구성요소로 설정하였으며 운전자 및 차량특성, 차두시간분포와 차량발생모형, 차량주행모형, 차로변경 및 간격수락모형, 경로선택모형을 주모의실험모형을 구성하는 부모형으로 결정하였다. 따라서 본 논문에서는 각각의 부모형들에 대한 최근의 연구결과들을 검토하고, 현실모사 능력과 함께 다른 부모형들과의 연계, 모의실험기의 구현상에서의 적합성 등을 고려하여 적정모형의 선정 및 수정, 새로운 부모형의 구축을 수행하였다. 구축된 부모형을 통합하여 교통모의실험기를 개발하였으며 구축된 모형의 타당성 및 적용성 검토를 위해 현장자료 및 가상자료를 이용한 검증을 수행하였다. 검증결과 모형의 목적인 교통제어 및 정보제공등의 시스템 대안의 평가에 이용 가능한 것으로 나타났다. 또한 본 논문의 연구결과는 교통제어 및 정보제공전략 대안의 평가뿐만 아니라 차량추종 및 차로변경 등의 미시적 교통모형 연구, 동적기종점 통행량 추정, 동적통행배정의 연구에도 활용할 수 있을 것으로 판단된다. 본 논문의 연구모형은 현단계에서는 현실의 모사 및 분석을 위한 도구보다는 새로운 대안들간의 비교평가를 위한 도구로 활용할 수 있을 것으로 판단된다. 이에 따라 현실모사의 정확도를 확보하기 위한 검증 및 개선이 필요할 것이며, 각 부모형들에 대한 계속적인 연구와 새롭게 발표되는 연구결과를 수용한 지속적인 개발이 필요할 것이다.유기적인 연계에 있음을 밝히고 있다. 건설을 위한 정책적 시사점과 동북아 연구개발정보 Portal 및 APEC APGrid 연구망 등의 구체적인 정보인프라 구축방안을 도출하였다.술 주기를 도출하고, 산업 내 평균 권리 청구 항목 수를 이용하여 각 산업의 기술 범위를 비교하였다. 각각의 동적 분석을 통해 시간에 따른 변화 양상이 관찰하였고, ANOVA 분석을 이용하여 통계적 유의성을 검증하였다. 본 연구는 현재의 기술 패러다임 내에서 Pavitt이 제시한 산업 분류의 근거를 보충 설명하였고 특허 정보를 이용하여 기술혁신의 산업별 유형에 대한 폭넓은 분석방법을 제시하였다.별 시간대별 효과분석을 통하여 정책의 시행여부가 결정되어야 할 것이다. 한편, 화물전용차선의 설치로 인한 물류비용의 절감을 보다 효과적으로 달성하기 위해서는 종합류류 전산망의 시급한 구축과 함께 화물차의 적재율을 높이고 공차율을 낮출 수 있는 운송체계의 수립이 필요한 것으로 판단된다. 그라나 이러한 화물전용차선의 효과는 단기적인 치유책일 수밖에 없기 때문에 물류유통 시설의 확충을 위한 사회간접자본의 구축을 서둘러 시행하여야 할 것이다.으로 처리한 Machine oil, Phenthoate EC 및 Trichlorfon WP는 비교적 약효가 낮았다.>$^{\circ}$E/$\leq$30$^{\circ}$NW 단열군이 연구지역 내에서 지하수 유동성이 가장 높은 단열군으로 추정된다. 이러한 사실은 3개 시추공을 대상으로 실시한 시추공 내 물리검층과 정압주입시험에서도 확인된다.. It was resulted from increase of weight of single cocoon. "Manta"2.5ppm produced 22.2kg of cocoon. It is equal to 9%

• Journal of Korean Society for Geospatial Information Science
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• v.22 no.2
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• pp.33-40
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• 2014

At present, Cadastral map of 2 dimensional is in the stream of changing it to 3 dimensional type supported by GPS and laser techniques. In addition, this steam can be explained at the same time with improvement of equipment of storing much information, support of equipment for imaginative 3D spatial information, and support of equipment of expressing land in 3D Cadastral. This study suggest to apply airborne lidar survey technique on cadastral map to acquire comparably and quickly detailed height of ground. For doing this, this study checked out credibility regarding accuracy of airborne lider survey. After choosing research area, this study has done the airborne lidar survey and acquire the result after surveying Cadastral Comparison Point to check out the accuracy of acquired results. In addition, this study check out the result of Cadastral Comparison Point and airborne lidar survey applied by paired sample t-test based on actual results. The result is that test statistics is 0.322 which is 5 % similar level and null hypothesis cannot be rejected, so this study found out that result of both survey ways are the same. Therefore, the result of airborne lidar survey can be utilized to build up 3D Cadastral information hereafter.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.6
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• pp.829-843
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• 2017

Subsea tunnel needs to be built over 50 km long to connect between nations and continents. However there are only 19 tunnels longer than 5 km until recently. And there is no history of constructing and operating tunnel longer than 50 km. In Korea, subsea tunnels with a length of more than 50 km are being planned, such as Korea~Japan, Korea~China, Honam~Jeju subsea tunnels. Because of the geographical conditions of Korea, most of these tunnels are inter-contry tunnels. So technology preemption for the subsea tunnel construction is getting more and more important. Most of these subsea tunnels are ultra-long tunnels under high water pressure conditions. So new technologies are required such as ventilation and disaster prevention of high-speed tunnels, securing of structural stability under high pressure conditions, and pressure reduction in high-speed conditions. These technologies are different from those of ground tunnels. Therefore, this paper describes the ultra-long subsea tunnel design under high water pressure of maximum 16 bars through the Honam (land) - Jeju (island) virtual subsea project. We proposed a reasonable solution to various problems such as securing structural stability in high pressure condition and ventilation disaster prevention system of ultra long-tunnel.