• Annals of Clinical Neurophysiology
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• v.9 no.2
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• pp.51-58
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• 2007

Autoimmune myasthenia gravis (MG) is the neuromuscular junction disorder mostly caused by antibody against the acetylcholine receptor (AChR antibody) at the muscle endplate. The goal of treatment is to induce and maintain remission, i.e., absence of symptoms, with the least cost-to-benefit ratio. Although corticosteroids are effective in inducing remission in most patients, they have numerous potentially serious adverse effects with their long-term use. In addition, some patients do not respond or are intolerant to the conventional treatment. In this article, we discuss the difficulties encountered in long-term immunosuppressive treatment of MG, and review useful tips for the use of corticosteroids. Long-term immunosuppressive agents that can be used in steroid-refractory or -dependent patients will be reviewed with their safety profiles and efficacy in MG.

• Journal of Chest Surgery
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• v.22 no.5
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• pp.766-774
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• 1989

Four neonates with critical pulmonary outflow obstruction underwent emergency palliative operation between February 1988 and May 1989 at the department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital. There were three boys and one girl, the mean age was 12.25 days [ranging from 3 days to 26 days], and the mean body weight was 3,625 gm [ranging from 3,450 gm to 4,200 gm]. Two patients had severe pulmonic valvular stenosis with intact ventricular septum, a third had pulmonary atresia with intact ventricular septum, and another had pulmonary atresia with ventricular septal defect. All were cyanotic, showed arterial desaturation with metabolic acidosis, and had congestive heart failure. To relieve the pulmonary outflow tract obstruction, we performed transventricular pulmonary valvulotomy [Brock operation] with a mosquito clamp in all cases without extracorporeal circulation. Three patients survived the operation and showed satisfactory postoperative results. The patient who had pulmonary atresia with ventricular septal defect expired 5 days after surgery. We consider transventricular pulmonary valvulotomy [Brock operation] with a mosquito clamp as one of the preferable procedures for critical pulmonary outflow obstruction in the neonatal period.

• International journal of thyroidology
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• v.11 no.2
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• pp.75-77
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• 2018

Tyrosine kinase inhibitor is known to prolong progression free survival in radioiodine refractory thyroid cancer patients. Fatigue/asthenia/malaise is one of most common adverse events by the tyrosine kinase inhibitor treatment, and management of the adverse event is important to keep the drug medication longer which is essential for the survival benefit. In the case report, a radioiodine refractory thyroid cancer patient receiving tyrosine kinase inhibitor experienced severe fatigue, and a pathologic fracture of right humerus occurred by slipping down which was tightly linked with the adverse event of the drug. The pathologic fracture was surgically well managed and the adverse event was well controlled by supportive managements combined with dose reduction of the tyrosine kinase inhibitor. The drug administration to the patient was kept more than 1 year without progression of the disease.

• The Journal of Internal Korean Medicine
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• v.40 no.1
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• pp.136-144
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• 2019

Objective: The purpose of this study was to report on the alleviation of symptoms of a myasthenia gravis (MG) patient after Korean medicine treatment. Methods: A 39 year-old male patient who suffered from MG was examined. The patient was treated with herbal medicine, acupuncture, and pharmacopuncture. The Myasthenia Gravis Composite (MGC) scale and Myasthenia Gravis Activities of Daily Living (MG-ADL) profile were used to assess the change of MG symptoms after Korean medicine treatment. Results: The MGC and MG-ADL scores indicated significant improvement after 14 days of treatment. In addition, the degrees of fatigue, dyspepsia, vomiting, sweating, and dizziness were decreased. Conclusion: This study may suggest that Korean medicine treatment could be effective in treating the symptoms of MG.

• Journal of Korea Society of Industrial Information Systems
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• v.27 no.2
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• pp.45-51
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• 2022

In this paper, an universal reduced input system that can represent Korean text message, English alphabet letter, special characters, and numbers is develpoed. The reduced keyboard input system has 5 number keys and 4 special function keys to reduce the complexity of inserting characters for the severely disabled. Also, mobile application is developed for the use of easy communication for the disabled.

• Annual Conference of KIPS
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• 2009.11a
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• pp.495-496
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• 2009

일반적으로 사용되고 있는 전동휠체어의 4바퀴 굴림 구조는 중증 장애인이나 노약자가 이동이 제한적이고, 전복 위험 등이 산재한다. 이러한 부분에서 오는 단점과 안전성의 문제를 해결하기 위해서 본 논문에서는 자유로운 동선이 가능하게 하고 센서를 적용하여 안전성을 확보하는데 목적을 두고 있다. 다양한 동선을 가지기 위해서 일반적인 바퀴가 아닌 "메카넘휠"을 장착하여 사용한다. 또 제어 방식에 있어서 핸들이라는 하나의 제어 장치 뿐만 아니라 심지어 게임기의 콘트롤러까지 다양한 범위를 수용하기 위해서 하드웨어 적인 확장이 용이한 환경을 사용한다.

• IEMEK Journal of Embedded Systems and Applications
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• v.18 no.2
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• pp.59-65
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• 2023

Currently, polysomnography is essential to diagnose sleep-related breathing disorders. However, there are several disadvantages to polysomnography, such as the requirement for multiple sensors and a long reading time. In this paper, we propose a system for predicting the severity of sleep-related breathing disorders at home utilizing measurable elements in a wearable device. To predict severity, the variables were refined through a three-step variable selection process, and the refined variables were used as inputs into three machine-learning models. As a result of the study, random forest models showed excellent prediction performance throughout. The best performance of the model in terms of F1 scores for the three threshold criteria of 5, 15, and 30 classified as the AHI index was about 87.3%, 90.7%, and 90.8%, respectively, and the maximum performance of the model for the three threshold criteria classified as the RDI index was approx 79.8%, 90.2%, and 90.1%, respectively.

• Proceedings of the Korean Society of Computer Information Conference
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• 2020.07a
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• pp.19-21
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• 2020

해가 갈수록 여러 요인들로 인하여 장애인 인구는 증가하고 있다. 하지만 이러한 장애인들을 위한 주변기기의 발전은 미흡한 상황이며 더욱이 장애인들의 여가를 위한 놀이문화, 기술들은 더욱 발전이 더딘 상태이다. 여가 활동은 장애인의 행복에도 직관적인 영향을 끼치는 중요한 부분이다. 따라서 본 논문에서는 장애인들 중 손과 같은 신체를 움직이기 어려운 중증 지체장애인을 위한 오목 플랫폼을 제안한다. 본 논문에서 구현한 오목 플랫폼은 음성인식을 기반으로 사용자가 오목알을 착수하고 싶은 좌표를 음성으로 입력시키면 Dobot 즉 로봇암을 통하여 착수점에 오목알을 착수한다. 실험에선 Google Vocie To Text API를 Python 환경에서 사용하여 사용자의 음성입력을 받았으며 Dobot Studio의 Script에서 입력된 음성 값을 오목판에 1대1로 맵핑시켜 정확한 위치에 착수할 수 있도록 구현하였다. 본 논문의 연구 결과를 응용하면 오목에만 국한되는게 아닌 다양한 보드게임을 구현할 수 있다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.100-101
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• 2021

In Korea, which has entered an aging society, 87% of the elderly population suffers from chronic diseases such as dementia and stroke, of which Alzheimer's dementia accounts for 71.3% of all dementia. In this paper, labeling verification was performed to review the error problem of deep learning results divided by Alzheimer's dementia MRI image into three stages.

• Proceedings of the Korean Society of Computer Information Conference
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• 2022.07a
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• pp.111-112
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• 2022

장애인 운전 지원센터는 지역별 편차가 심하고 인력 부족 등의 문제로 배우고자 하는 장애인의 수요를 충족하지 못하고 있는 상황이다. 본 논문에서는 시뮬레이터를 활용하여 가상현실을 통한 장애인 운전 교육 시뮬레이터 모델을 제안한다. 가상현실 기법을 활용하여 시뮬레이터를 구성하고 운전 교육데이터를 시뮬레이터에 적용하여 모델을 구성하였다. 실질적인 교육내용을 기준으로 프로세스를 구성하였으며, 제안 모델을 활용하면 운전 교육이 어려운 중증장애인들도 시뮬레이터를 통한 간접적인 운전을 경험함으로써 삶의 질 또한 향상되는 것을 기대할 수 있다.