• Journal of Nutrition and Health
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• v.21 no.6
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• pp.410-420
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• 1988

This study were performed to investigate effect of dietary cadmium(Cd) and protein levels on growth, body protein metabolism and Cd toxicity in growing rats. Forty eight male rats of Sprague-Dawley weighing 113$\pm$2g were blocked into 6 groups accoridng to body weight. Dietary protein were given at the levels of 7, 15 and 40% of diet and Cd (200ppm)were either added or not. The result obtained were summerized as follow; 1) Food intake, weight gain, FER PER, liver and kidney weight, weight and length of bones, hematocrit, and hemoglobin content in Cd-added groups were low than those in Cd-free groups. 2) Serum total protein showed no significant difference with Cd addition, but it was significantly lower in low protein diet groups. Liver protein in Cd-added groups was lower than Cd-free groups, and was tend to be increased with increasing dietary protein level. 3) Daily urinary and fecal nitrogen excretions in Cd-added groups were lower than Cd-free groups, and were increased with increasing dietary protein level. 4) Cadmium contents in blood, liver, kidney, and femur were tend to be decreased with increasing dietary protein level. Especially, Cd content in kidney of Cd-added groups was significantly decreased with increasing dietary protein level. 5) Daily urinary and fecal Cd excretions were tend to be increased with increasing dietary protein level, and Cd-added-high protein diet group showed the highest Cd excretion among the Cd-added groups, Cd absorption ration and Cd retention ratio were tend to be decreased with increasing dietary protein level.

• Journal of Nutrition and Health
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• v.25 no.5
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• pp.360-378
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• 1992

This study was performed to investigate effect of dietary protein and calcium levels on cad-mium intoxication in rats. Adult Sprague-Dawley male rate(245$\pm$21g) were blocked into 18 groups of 7 animals according to body weight Nine experimental diets different with protein(40%, 15%, 7%) and calcium (1.3%, 0.6%, 0.1%) levels were prepared. Nine groups of animals were fed each diet with 50ppm cadmium in drinking water and the other 9 groups without cadmium for 30days. Results were summarized as follows: 1) Body weight gain F. E. R(Food Efficiency Ratio) and weights of liver kidney and femur were higher in high protein groups among cadmium exposed groups. 2) Cadmium contents in liver and intestine were higher in rats fed high protein diet or low calcium diet among cadmium exposed groups. Fecal cadmium excretion was highest in high protein-high calcium diet group among cadmium exposed animals. Metallothionein contents in liver kidney and intestine were higher in animals exposed to cadmium and fed high protein diets. 3) Gel filtration chromatography of cytosolic solution showed that the higher dietary protein and calcium levels were the more cadmium was found in metallothionein fractions. 4) No gross histopathological change was seen in liver kidney and intestine of cadmium exposed rats. However a significant increase of smooth endoplasmic reticulum which was alleveated by high protein-high calcium diet was observed. Results obtained indicated that not only high protein diet but also high calcium diet showed preventive effect on cadmium intoxication by increasing the induction of metallothionein syn-thesis and decreasing the cadmium absorption.

• Journal of the Korean Society of Food Science and Nutrition
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• v.23 no.4
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• pp.574-580
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• 1994

The effect of dietary zinc(Zn) levels on cadmium (Cd)-induced hepatotoxicity was studied in serum and liver of rats. Adult male Spraque-Dawley rats were fed on diets containing one of three levels of zinc carbonate(0, 56, $560\mu\textrm{g}/kg$ diet) and Cd-treated groups were administrated oral intubation with cadmium chloride 95.0 mg/kg of body weight) at the sametime once a week. Net weight gain (NWG), feed intake (FI) and feed effciiency ratio (FER) in Zn deficiency groups significantly decreased as compared to that of control and excessive groups. Cd oral intubation caused a decrease in NWG and FI but an increase in Zn deficiency group in FER. GSH-Px, GST and catalase activity showed significant decrease in Zn deficiency and Zn excessive group. LPO content in liver significantly increased in Zn deficiency group. Cd oral intubation increased the content of LPO in Zn deficiency group as compared to control. GSH content and GST activity of hepatic tissue significantly decreased in Zn deficiency and excessive group. The activity of AST and ALT in serum were markedly increased in Zn deficiency, Zn excessive and Cd-treated groups. LDH and ALP activities significantly increased in Cd-treated group while ALP activity decreased by Zn deficiency. It was observed that the livers of rats exposed to Cd and Zn excessive group showed a marked increase of hepatic enzyme as compare to only Cd-treated in rats.

• Journal of Science Education
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• v.47 no.3
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• pp.251-262
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• 2023

In this study, we examine other factors that may contribute to the decline in students' academic performance and educational attainment. Many media reports, as well as previous studies, have suggested that virtual learning is the main reason for the decline in students' academic performance. However, the 2020 National Student Achievement Survey, which was conducted in conjunction with the COVID-19 Distance Learning Environment Student Survey, showed that students were highly satisfied with distance learning (70-80%), and the analysis of the National Assessment of Educational Achievement showed that students' academic performance had already been declining year by year since 2017, with a general downward curve. For further confirmation, we analyzed the performance of high school students on mock exams and found that their performance was not normally distributed, but rather a right-skewed U-shaped distribution with a shrinking number of medians and severe polarization. We found that this phenomenon is not simply because of the mode or quality of the virtual classroom, but to a variety of factors, including environmental influences such as care and management at home, changes in investment in private education, increased time spent on online devices while taking virtual classes at the bottom, and increased time spent watching online content, games, and videos that are not related to learning.

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.326-330
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• 2009

본 연구는 일반 성인남성과 직업군인의 건강형태 및 의료이용에 대해서 2005년도 국민건강 영양조사의 자료를 질병관리본부로부터 획득하여 분석하였고 그 결과를 보면 전체조사 대상자는 8,384명으로 21세~55세의 일반성인남성과 직업군인만을 선정하였으며, 직업군인은 76명, 일반 성인 남자는 8,308명이었다. 보건의식 행태 분포에서 보면 현재 흡연상태는 일반인에 비해 직업군인이 높고, 주관적 체격인식은 일반인의 경우 비만 또는 매우 비만이라 인지하는 비율이 직업군인에 비하여 높게 나타났지만, 실제로 지난 1년간 체중조절 여부는 일반인이 오히려 직업군인에 비해 높게 나타났다. 또한 직업군인의 보건의식 행태는 평균 연령(p<0.05)에서 통계적으로 유의한 차이가 있는 것으로 나타났다. 월간 침상와병일수는 직업군인이 상대적으로 높았으나 월간 결석, 결근일수는 오히려 낮게 나타났다. 더불어 월간 결석, 결근일수(p<0.05)는 통계적으로 유의한 차이를 나타났다. 연간 입원이용율은 일반인이 높았으며, 평균 재원일수, 건당 평균 입원기간은 일반인에 비해 직업군인이 길었다. 2주간 외래 이용율은 일반인이 17.2%, 직업군인이 21.6%로 직업 군인의 외래이용이 많았고, 평균 외래이용 횟수에서도 일반인이 1.92, 직업군인이 2.44로 직업군인이 많았다. 이용한 보건의료기관의 종류에서는 일반인은 의원급이, 직업군인은 병원급의 외래이용이 많았고 2주간 약국 이용율은 직업군인이 16.2%로 일반인 22.0% 에 비하여 낮았다. 연간 사고 및 중독 발생자율은 직업군인이 9.5로 일반인 7.9에 비하여 높게 나타 났으며, 사고 및 중독 발생횟수에서는 일반인이 직업군인에 비하여 높았다. 의도성별 분포(p<0.05), 주치료기관(p<0.05)은 통계적으로 유의한 차이가 나타났다. 본 연구를 통해 일반적 특성, 보건의식행태, 건강수준의 분석 및 일반적 특성을 보정한 상태에서 일반 성인남성과 직업군인의 보건의식 행태와 의료이용 분포를 비교 분석한 것으로 향후 직업군인의 건강 증진을 위한 효과적인 교육과 정책수립에 필요한 기초자료가 될 수 있을 것으로 기대해 본다.

• The Journal of the Korea Contents Association
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• v.17 no.11
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• pp.632-640
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• 2017

Purpose: This study was to investigate the difference of attitude toward caring for alcoholics of nursing college students according to degree of parents' drinking problem. Methods: The subjects of this study were 281 students in the second and fourth grade students in nursing departments of 4 Universities located in G city. Data were analyzed by the mean and standard deviation, t-test. and ANOVA using SPSS 22.0 program.. Results: Parents' problem drinking perceived by the subjects was $3.70({\pm}5.85)$, $1.25({\pm}1.71)$ in the social drinking group(n=225), $8.59({\pm}2.07)$ in the alcohol abuse group(n=29), and alcohol dependence group (n=27) was $18.85({\pm}5.17)$ points. The average attitude toward caring for alcoholics was $45.25({\pm}6.49)$. The attitude toward caring for alcoholics showed a statistically significant difference depending on whether or not-they participated in the nursing practice of alcoholics. The attitude toward caring for alcoholics in nursing college students was negative as the parents' problem drinking was severe. Conclusion: The results of this study can be used as basic data for the development of psychiatric nursing education and counseling program for nursing college students whose parental drinking problems are serious in the future.

• Journal of the Korean Society of Radiology
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• v.12 no.1
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• pp.53-64
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• 2018

Using the AUDIT-K (Korean versions of alcohol use disorders identification test), it was able to select a large number of potential danger drinkers who routinely live. There were no statistically significant differences in age, religion, marital status, occupation, family history of alcohol drinking, age at onset of alcohol use, smoking, and BMI (body mass index). However, only education and drinking periods were statistically significant. These results are consistent with the previous study, which suggests that alcohol consumption is higher among men who are educated. The level of education also suggests that there is a need to look at the differences depending on what you learned and how. Alcohol consumption by education also shows different results. Also, drinking at a young age will lead to a longer drinking period, which is consistent with previous studies on the age at onset of drinking. In this study, drinking period was the most important factor of alcohol use disorder and it is considered that measures and education of national government system which can delay drinking age as much as possible is needed as a method to shorten drinking period.

• Journal of Music and Human Behavior
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• v.11 no.2
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• pp.19-39
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• 2014

This study investigated whether a song psychotherapy based on the change stages of alcohol addiction impacted the change readiness of alcoholics. The song psychotherapy intervention consists of six activities (listening to a song, singing, songwriting, song sharing, lyrics analysis, and discussion and analysis of a song), which considers the change stages of alcohol addiction. A total of 64 inpatients diagnosed with alcoholism were randomly assigned to either the control (n = 33) or experimental group (n = 31). The experimental group took part in the intervention program for 45 minutes twice a week for 6 weeks (total of 12 sessions). The intervention effect was evaluated with SOCRATES-K. The results showed that the SOCRATES-K score significantly increased by 14.6% (p < .001) for the experimental group, whereas it remained almost unchanged (0.8% increase, p = .141) in the control group. For subcategory scales, the experimental group showed the highest increase in the ambivalence factor, followed by the recognition and taking-steps factors. Meanwhile, no significant changes in all three scales were found in the control group. Therefore, the song psychotherapy intervention based on the change stages of alcohol addiction was found to significantly increase the change readiness of alcoholics.

• Journal of Preventive Medicine and Public Health
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• v.28 no.1 s.49
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• pp.27-42
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• 1995

The in vivo and in vitro humoral and cell-mediated immune responses of lymphocytes of BALB/c mouse exposed to mercury chloride$(HgCl_2)$ were investigated. In vitro exposure of the splenocytes to mercury chloride produced overt cytotoxicity in 3 hours period. The $IC_{50}$(the concentration required to inhibit a splenocyte viability by 50%) for mercury chloride was >0.1mM for cytotoxicity. In vivo mercury chloride exposed mice were significantly depressed delayed type hypersensitivity(DTH) response to sheep red blood cells(SRBC) in a dose-dependent manner compared with control group. Mercury chloride inhibited the proliferative responses of splenocytes to lipopolysaccharide, pokeweed mitogen, concanavalin A and phytohemagglutinin in a dose-dependent manner. Hemagglutinin response to SRBC in mercury chloride exposed mice was significantly depressed in a dose-dependent manner compared with control group. After 7 weeks of mercury chloride exposure in vivo, mercury chloride induced an increase of nonspecific serum $IgG_1$ and IgE levels in BALB/c mice.

• Proceedings of the Safety Management and Science Conference
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• 1999.11a
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• pp.343-343
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• 1999

아크용접은 산업전반에 걸쳐 그 생산기반에 없어서는 안될 필수기술로써 자동차 및 조선, 항공우주산업에 이르기까지 경제기반에 미치는 파급효과가 매우 크다. 그러나 이 아크용접을 하게 되면 각종 가스와 미세입자로 이루어진 흄이 발생하게 되는데 이들은 작업자들의 건강에 많은 영향을 미치는 것으로 보고되어 있다. 용접흄에는 용접재료 및 용접공정에 따라 다양한 유해원소가 포함되어 있고 그 종류에 따라 인체에 미치는 잠재적 독성효과도 매우 광범위하다. 최근 국내에서는 용접사들 중에 용접흄에 포함된 중금속 중 Mn중독에 의한 파킨스씨병 환자들과 Cr중독에 의하여 콧속 연골에 구멍이 뚫리는 비중격천공(鼻中隔穿孔) 환자들이 직업병으로 판정 받아 산재요양이 승인된 사례가 있다. 이러한 계기로 인하여 용접사들의 용접기피 현상이 심화되고 작업환경에 대한 법적규제는 선진 외국뿐만 아니라 국내에서도 한층 엄격하게 강화되고 있는 실정이다. 따라서 이제는 작업자와 사용자 모두 용접흄에 대한 인식의 전환이 요구되는 때이며 여러 분야에서 이러한 용접흄에 대한 연구가 활발히 진행되어야 한다. 해외에서는 이미 용접흄에 대한 연구가 활발히 진행되어 왔으나 국내의 경우는 매우 미비한 상태이며 용접산업의 미래 영향력이나 필요성을 고려할 때 국내에서도 적극적인 관심을 가져야 할 부분으로 판단된다. 본 연구에서는 아크용접공정에서 발생하는 흄의 특정 중금속 성분이 인체에 치명적인 악영향을 미치는 것에 착안하여 여러 종류의 용접재료에서 발생되는 용접흄의 중금속 분포를 조사하여 비교하였다. 이것은 향후 용접재료별 및 용접공정별 발생되는 흄의 유해원소를 저감시킬 수 있고 또한 각종 유해원소의 노출기준 및 평가기준을 마련할 수 있는 기초data로써 도움이 되리라 사료된다.동, 공정중재고가 줄어드는 결과를 보였고, 가동률 수준이 높을수록 ORR 방법간의 차이가 크게 나타났다. 그리고 부하평준화 기능은 Order Release 정책의 유효성에 별 영향을 주지 않는 것으로 나타났다. 결론적으로, Order Release 방법은 우선순위규칙간의 성능차이를 줄이거나, 대체할 수 통제 기법이라기보다는 우선순위규칙을 보완하여 공정중재고와 작업현장에서의 리드타임, 리드타임의 편차를 줄여주는 역할을 한다고 볼 수 있다. 그리고, 계획시스템이 존재하여 계획오더가 일정기간간격으로 이송되는 환경에서 특히 유용하다는 결론을 얻었다. 알 수 있었다. 것인데, 제조업에서의 심각한 고비용, 저효율 문제 를 해결하기 위해 필수적으로 도입해야만 하는 실정이다. 또한 소비자의 다양한 요구로 인 하여 제품의 종류와 사양면에서 심한 변동을 보이는 시장 수요에, 신속한 정보처리로 대응 하는데도 크게 기여하고 있다. 이에 본 연구에서는, 자동차 Job Shop의 동기화 생산방식을 지원하는 동기화 생산시스템의 구축 모델을 제시하고자 한다.과로 여겨지며, 또한 혈청중의 ALT, ALP 및 LDH활성을 유의성있게 감소시키므로서 감잎 phenolic compounds가 에탄올에 의한 간세포 손상에 대한 해독 및 보호작용이 있는 것으로 사료된다.반적으로 홍삼 제조시 내공의 발생은 제조공정에서 나타나는 경우가 많으며, 내백의 경우는 홍삼으로 가공되면서 발생하는 경우가 있고, 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(min