• Title/Summary/Keyword: 준 조절효과

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Effect of Zanthoxylum piperitum Extract on Human Skin Protection from UVB by Regulation of COP1 and PPAR-α (초피나무 열매 추출물의 COP1 및 PPAR-α 조절을 통한 자외선에 대한 피부 보호 효과)

  • Kim, Yun-Sun;Kim, Yumi;Lee, Sanghwa
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.4
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    • pp.393-401
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    • 2016
  • Ultraviolet (UV) irradiation from the sun is the primary environmental factor that causes skin damages including skin cancer and premature skin aging. Because, even the most powerful sunscreen can't always afford enough protection, it is necessary to enhance the defensive power of skin against UV. Recently, constitutive photomorphogenic protein-1 (COP1) has shown to contribute to the regulation of UVB response of keratinocytes. In this study, we represent that COP1 and its associated protein, de-etiolated 1 (DET1), might participate in photoaging process in human skin as Arabidopsis COP1 does sun-protective function in plants. After UVB irradiation, the decrease of COP1 and DET1 mRNA expression was followed by the increase of c-Jun total protein. Moreover, transfection with DNA vectors expressing COP1 and DET1 down-regulated the c-Jun total protein. We found that Zanthoxylum piperitum extract (ZE) up-regulated the expression of COP1 and DET1 on human keratinocytes, and inhibited the expression of MMP1 which is one of the genes regulated by c-Jun signal. In addition, ZE has been reported to stimulate PPAR-${\alpha}$ and strengthen the skin barrier. We found that ZE decreased the UVB-induced IL-6 and IL-8 in NHEK cells. In human study, ZE protected skin against UV-B induced erythema and erythema-induced pigmentation. These results indicate that ZE could be useful for the protection against the adverse effects of UV irradiation through various mechanisms.

A Study of Pathological Gaming Model in Young Adolescents from the Perspective of Escape Theory (도피이론을 통한 청소년 게임 과몰입 영향모델 분석)

  • Lee, Daeyoung;Lee, Seungje;Jeong, Eui Jun
    • Journal of Korea Game Society
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    • v.20 no.2
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    • pp.3-12
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    • 2020
  • This study examined a pathological gaming model based on escape model. With a data set collected from 825 Korean adolescents, the associations among academic stress, depression, self-esteem, self-control, and pathological gaming were tested. Academic stress increased the degree of depression while it decreased self-esteem and self-control. The declined self-control, in turn, exacerbated pathological gaming. Results and implicaitons were discussed.

The Effect of Individual Stress and Team Cohesion and Mastery Climate on Knowledge Creation (개인의 스트레스, 집단의 학습분위기와 응집력이 지식창출에 미치는 영향)

  • Kang, So-Ra;Kim, Min-Sun
    • Proceedings of the KAIS Fall Conference
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    • 2010.05b
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    • pp.807-810
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    • 2010
  • 본 연구는 스트레스가 지식창출에 미치는 영향을 보고자 한다. 즉, 개인의 목표에 대한 그리고 직무와 관련된 스트레스는 지식창출에 부정적 영향을 미친다는 연구들이 제시되고 있는데, 이때 팀의 어떠한 요소들이 이러한 부정적 영향을 감소시키고 지식창출에 기여할 수 있을지를 파악하고자 한다. 구체적으로 지식창출을 위해 자원에 비해 과도하게 설정된 목표로 인한 목표 스트레스(goal stress of resource inadequacy)와 지식창출을 위한 업무과정에서 발생하는 직무 스트레스(job stress)는 지식창출에 부정적 영향을 미칠 것이다. 그러나 지식창출을 위해 구성된 팀구성원들이 열심히 배우려고 하고 실패도 두려워하지 않는 분위기(팀 학습분위기) 속에서 강하게 결속되어 있다면(팀 응집력) 스트레스로 인한 지식창출에 대한 부정적 영향은 약화될 것으로 판단된다. 따라서 본 연구에서는 집단수준의 변수와 개인수준의 변수를 동시에 고려해야 하는 본 연구의 성격상 최근에 많이 사용되고 있는 다수준접근방법을 적용하여, HLM 6.08을 사용한 위계적 선형 모형분석을 수행하였다. 연구결과, 직무 스트레스는 지식창출에 부정적 영향을 미쳤으나 목표 스트레스는 유의한 영향을 미치지 않은 것으로 나타났다. 또한 팀의 학습분위기는 지식창출에 긍정적 영향을 미쳤으며, 목표 스트레스와 지식창출간의 관계에 조절효과를 하는 것으로 나타났다. 팀의 응집력 역시 지식창출에 긍정적 영향을 미치는 것으로 나타났다.

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An Empirical Analysis of The Relationship between Hospital Employees' Perception of Organizational Politics, Organizational Effectiveness, and The Moderating Role of Organizational Trust (병원조직 구성원의 조직정치지각과 조직유효성과의 관계: 조직신뢰의 조절효과)

  • Yi, Kyunghee;Yoon, Hyejeong;You, Myoungsoon;Lee, Wang-Jun
    • Korea Journal of Hospital Management
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    • v.22 no.2
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    • pp.70-86
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    • 2017
  • The purpose of this study was to empirically investigate the relationship between hospital employeesʼ perceptions of organizational politics, organizational effectiveness such as job satisfaction, organizational commitment, and turnover intention. We also evaluated the moderating effect of organizational trust on the relationships between POPs and organizational effectiveness. By analyzing 726 employeesʼ data including physicians, nurses, medical technicians, and administrators from one private hospital, POPs was found to have had a highly negative relationship with job satisfaction and organizational commitment while a highly positive relationship with turnover intention. Furthermore, organizational trust moderated the relationship between POPs and job satisfaction, and also POPs and turnover intention, while no moderating effect appeared between POPs and organizational commitment. Within the organization, employees who are in a group with high organizational trust have low job satisfaction and high turnover intention when they have high POPs rather than a group with low organizational trust. Further the implications of these results and future directions of the study have been discussed.

RF Predistortion Techniques using 2nd Harmonics and Difference Frequency for Linearization of Power Amplifier (전력 증폭기의 선형화를 위해 2차 고조파와 차주파수를 이용한 전치왜곡 기술)

  • 박진상;조경준;장동희;김종헌;이병제;김남영;이종철
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.4
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    • pp.356-362
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    • 2003
  • In this paper, we propose a predistortion technique which uses a novel combination of the second harmonic technique and the difference frequency technique to achieve independent control of the 3rd and 5th order intermodulation products generated by the PA. The second harmonic and difference frequency terms are generated using an envelope detector and two frequency multipliers. The RF predistorter has capability to independently control of the 3rd and 5th order intermodulation products so that high power amplifier is optimized for linear characteristics. From the measurement results, over the frequency band 2137.5 MHz to 2142.5 MHz, ACPR reduction of 11 dB is obtained for a single 30 dBm W-CDMA carrier.

창업가의 예상된 후회가 창업 행동에 미치는 영향에 관한 연구: 자기 충족적 예언과 열정의 조절효과를 중심으로

  • Won, Chi-Un;Bae, Tae-Jun
    • 한국벤처창업학회:학술대회논문집
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    • 2020.06a
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    • pp.107-112
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    • 2020
  • 많은 사람들은 미래에 발생할 일에 대한 결정을 내리기 전 수 많은 생각과 심리적 변화를 겪게 된다. 특히 우리 삶에서 자신의 직업과 같은 경제적 및 사회적 측면에 대한 고려와 함께 중요한 선택을 하게 되는 상황에서 그 선택은 미래에 경험하게 될 후회의 정도에 따라 현재의 행동이 결정된다. 이러한 심리적 기제는 이미 심리학과 마케팅 분야에서는 감정 및 정서적 요인들이 의사결정 과정에 직접적이고 중요한 영향을 미친다는 사실에 공감하며 관련 연구들이 활발히 이루어져 왔다. 이처럼 창업 분야에서도 예비창업가들이 창업을 결정하기 위한 중요한 심리적 요인으로 후회라는 감정이 직접적으로 영향을 미치는지 확인할 필요가 있다. 따라서 본 연구에서는 많은 창업가들의 의사결정에서 발생되는 예상되는 후회(anticipated regret)가 창업 행동(entrepreneurial behavior)에 영향을 미치는 가를 살펴보고자 하였다. 그리고 이와 아울러 창업가의 예상되는 후회가 창업 행동에 영향을 미칠 때, 창업가의 자기 충족적 예언(self fulfilling prophecy)과 창업가적 열정(entrepreneurial passion)의 수준이 어떠한 영향을 미치는지 알아보고자 한다. 이를 위해 창업가의 예상되는 후회와 목표지향성, 그리고 창업가적 열정에 대한 선행연구를 검토함으로써 가설을 설정하였다. 그리고 이를 검증하기 위해 창업가 145명을 대상으로 두 차례에 걸쳐 설문을 실시하여 연구를 진행하였다.

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Improvement of Attention Span and Impulsivity of Children with Attention Deficit Hyperactivity Disorder through Structured Violin Learning (주의력결핍과잉행동장애 아동의 집중력 향상과 충동성 조절을 위한 바이올린 교습 중심의 음악치료 사례 연구)

  • Kang, Hyun Jung
    • Journal of Music and Human Behavior
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    • v.3 no.2
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    • pp.1-14
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    • 2006
  • The purpose of this study is to examine the effect of violin learning as to enhance the attention span and impulsiveness of children with Attention Deficit Hyperactivity Disorder(ADHD). Three children with ADHD, grade 2, 3, 4 were selected to participate in the research. A total of 15 session were given during 8 week time span, including a final performance session. For measurement, Korean-Child Behavior Checklist(K-CBCL), Home Situation Questionnaire-Revised (HSQ-R), Conners Teacher Rating Scale-Revised (CTRS-R) were administered before and after the implementation. Other behavioral checklist were used to record inappropriate or interruptive behaviors. The results showed that violin learning has increased attention span and reduced impulsive behaviors of all three children with ADHD. Along with these changes, the identified inappropriate behaviors reduced as sessions progressed. Also the changes observed within the music environment were generalized to non-music environment, such as family and school. These results also indicate that violin can be a therapeutic medium used in music therapy setting to bring positive changes for children with ADHD problems.

Performance Analysis of FA Allocation Schemes of CDMA Radio Networks (CDMA 무선망의 FA 할당 방식 성능 분석)

  • 김장욱;유병철;오창헌;조성준
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 2000.11a
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    • pp.59-62
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    • 2000
  • 현재 CDMA 시스템에서 통화채널의 주파수 할당 방식에 Hashing 알고리즘이 사용되며, Hashing알고리즘에 의해 FA(frequency assignment)간 부하 균형을 유지하고 있다. Hashing 알고리즘은 모든 가입자 번호를 각 FA에 균일하게 할당하지만, 개별 기지국의 가입자 분포는 각 FA별로 반드시 균일하게 분포되지는 않는다. 이런 FA간 가입자 분포의 불균형은 해당 기지국의 과부하로 인식되어 조기 FA 증설이 요구되며, 해당 과부하 FA의 통화품질 열화를 일으킨다. 따라서 부하 균형에 따라 통화채널의 FA할당을 조절하기 위한 Hashing 후 강제 할당 방식인 OFD(optional forced distributio)을 제안하고 이를 CDMA 시스템에 적용하여 부하 균형의 개선 효과를 얻었다.

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The Influence of Inpatient's Experience on Hospital Recommendation Intention - Focusing on the Moderating Effects of Health Condition - (입원 환자경험이 병원 추천의도에 미치는 영향 - 건강상태의 조절 효과를 중심으로 -)

  • Lee, Kyoungsook;Kim, Jeoungae;Lee, WangJun
    • Korea Journal of Hospital Management
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    • v.22 no.3
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    • pp.133-143
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    • 2017
  • Purpose : This study is to analyze the inpatients's experience of medical services provided by hospital including medications, treatments, and environment. Based on the results of surveys conducted as part of the inpatient experience evaluation in A hospital in Goyang, Gyeonggi province. Methodology : A sample of 300 adults aged 19 years or older who had more than one day of hospitalization was selected. The questionnaire was conducted from April 3rd to June 21st, 2017 by telephone. Findings : It is found that recommendation intention influenced by medical services, hospital environment, medication treatment process. but it turns out that there is no moderate effects of health condition between patient's experience and recommendation. Practical Implication : In order to improve the inpatient experience, there should be a way to improve experience in providing patient-centered services in the hospital s environment, medication and treatment.

Fuzzy control of hybrid base-isolator with magnetorheological damper and friction pendulum system (MR 감쇠기와 FPS를 이용한 하이브리드 면진장치의 퍼지제어)

  • Kim, Hyun-Su;Roschke, P.N.;Lin, P.Y.
    • Journal of the Earthquake Engineering Society of Korea
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    • v.9 no.1 s.41
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    • pp.61-70
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    • 2005
  • Shaking table tests are carried out on a single-degree-of-freedom mass that is equipped with a hybrid base isolation system. The isolator consists of a set of four specially-designed friction pendulum systems (FPS) and a magnetorheological (MR) damper. The structure and its hybrid isolation system are subjected to various intensities of near- and far-fault earthquakes on a large shake table. The proposed fuzzy controller uses feedback from displacement or acceleration transducers attached to the structure to modulate resistance of the semi-active damper to motion. Results from several types of passive and semi-active control strategies are summarized and compared. The study shows that a combination of FPS isolators and an adjustable MR damper can effectively provide robust control of vibration for a large full-scale structure undergoing a wide variety of seismic loads.