• Title/Summary/Keyword: 종대황

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Extracts of Rheum undulatum L. Inhibits COX-2 Activities in Lipopolysaccharide-stimulated Raw 264.7 Cells (종대황 추출물의 COX-2 활성 억제 효과)

  • 하혜경;이제현;김정숙
    • Biomolecules & Therapeutics
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    • v.8 no.1
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    • pp.73-77
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    • 2000
  • Rheum undulatum L. has been used as Rhei Radix in Korean Pharmacopea although their pharmacological effects were not studied much. In this studym, we tested anti-inflammatory effect as a representative activity of Rheum undulatum L. extracts using cyclooxygenase (COX)-2 inhibition. Murine macrophage, Raw 264.7 cells were incubated with lipopolysaccharide (1 $\mu\textrm{g}$/ml) to induce COX-2. The prostagladin $E_2$ ($PGE_2$) levels as an indicator of COX-2 activity were determined in the culture medium using ELISA. Inhibition of acetylsalicylic acid (ASA) as a standard, aloe-emodin, chrysophanol, rhein, 80% ethanol extract of Rheum undulatum L. (Ex) and ether fraction (Fr) after acid hydrolysis of Rheum undulatum L. were tested in induced COX-2 described above. $IC_{50}$ values were 0.082 $\mu\textrm{g}$/ml for ASA. 181 $\mu\textrm{g}$/ml for aloe-emodin, 3.65 $\mu\textrm{g}$/ml for emodin, 144 $\mu\textrm{g}$/ml for chrysophanol, 39.8 $\mu\textrm{g}$/ml for rhein, 141 $\mu\textrm{g}$ of herb/ml for Ex, and 95.7 $\mu\textrm{g}$ of herb/ml for Fr. We found that Ex and Fr of Rheum undulatum L. were more effective than other anthraquinones, since their $IC_{50}$ are lower than others.

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Evaluation of Plant Growth according to the Wavelength Characteristics of the LED Light Source (LED광원의 광파장 특성에 따른 식물의 성장도 평가)

  • Hwang, Jong-Dae;Ko, Dong-Su
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.13 no.5
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    • pp.98-106
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    • 2014
  • This study was carried out to evaluate the plant growth rate according to the wavelength characteristics of LED light sources. In order to achieve this, red, green, blue and white LEDs were arrayed in a rectangle array consisting of LED modules which can be combined with each other.. This can facilitate the selection of the optimal characteristics of the light from monochromatic red, green, blue and white LEDs or mixed LEDs for plant growth. Experiments to evaluate the growth rate according to the wavelength characteristics of the LEDs with several plants, in this case ice plants, lettuce, barley, broccoli and chives, were performed.

A Study on the Development of a Step Cutter with Hybrid Process of Drilling and Boring (드릴, 보링 공정복합형 스텝 커터의 개발)

  • Hwang, Jong Dae;Heo, Yun Nyoung;Oh, Ji Young;Jung, Yoon Gyo;Cho, Sung Lim
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.7 no.3
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    • pp.30-35
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    • 2008
  • As demands for being economical, precise drilling process is on the increase. Therefore, the objective of this study is to develop a step cutter that can be controllable through micro dimension and can be changed from separate manufacturing processes of drilling and boring into an integrated one. In order to attain this object the step cutter is designed with a 3D geometric modeling and the design could be modified easily by using parametric modeling methodology. Also, collision is not occurred during manufacturing process because of cutting simulation. The step cutter is assembled by parts made up of 5-axis machining and sintering. Validation tests are accomplished. They show that developed cutter has characteristics such as reduction of machining time as well as the good surface roughness of the machined hole. Indeed, reliability could be obtained from a durability test.

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The Development of Shape Guided Automatic Deburring Machine for Mold Products (금형제품용 형상안내형 자동면취기의 개발)

  • Hwang, Jong-Dae;Kim, Jin-Seob;Jung, Yoon-Gyo
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.10 no.1
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    • pp.16-22
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    • 2011
  • Recently, the deburring process which is last process of manufacture is one of the important process for complete product. The development of shape guided automatic deburring machine is essential because manual deburring process has very irregular quality and higher error rate as well as consider irregular shape radius. In order to develop of shape guided automatic deburring machine, in this study, we conducted 3D design, assembly, machine simulation and structural analysis using CATIA. Also, we conducted to make automatic deburring machine and conducted a performance test.

Control of Low-level Malodorous Reduced Sulfur Compound with Visible-light Irradiation

  • Sin, Myeong-Hui;Kim, Jong-Tae;Jang, Jong-Dae;Kim, Mo-Geun;Gwon, Gi-Dong;Lee, Hyeon-Cheol;Jo, Wan-Geun
    • Proceedings of the Korean Environmental Sciences Society Conference
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    • 2008.11a
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    • pp.103-106
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    • 2008
  • 악취물질 중 특히 황계열 물질인 Dimethyl sulfide(DMS)을 가시광선 조사아래 실내환경조건에서 광촉매 제거효율을 평가하였다. 농도에 의한 영향에서 1000, 20000$\mu$g/m$^3$에서 램프를 켜자마자 활성이 저하되는 것을 발견하였다. 이는 촉매 산화반응에 의한 부산물의 흡착 때문이다. 습도에 의한 영향평가에서 습도가 낮을 수로 제거율도 떨어졌다. 이는 유기물 산화를 일으키는 라디칼이 물분자에 의해 생성되기 때문에 낮은 습도에서 OH 의 공급원인 물분자의 결핍이 생겨 Dimethyl sulfide(DMS)제거효율을 떨어뜨렸다.

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Photocatalysis of Dimethyl disulfide in a Continous Flow Reactor : Deactivation and Regeneration

  • Sin, Myeong-Hui;Kim, Jong-Tae;Jang, Jong-Dae;Kim, Mo-Geun;Lee, Jin-U;Gwon, Gi-Dong;Jo, Wan-Geun
    • Proceedings of the Korean Environmental Sciences Society Conference
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    • 2008.11a
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    • pp.96-99
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    • 2008
  • 악취물질 중 특히 황계열 물질인 Dimethyl disulfide(DMDS)는 광촉매 산화 시 촉매비 활성에 의해 촉매의 효율이 떨어진다. 이는 Dimethyl disulfide(DMDS) 분해과정에서 발생되는 중간생성물이 촉매 표면에 강하게 흡착되기 때문이다. 이러한 비활성을 해결하기 위해 촉매를 재생하여 사용할 수 있다. 'Burning out'에 의한 재생은 촉매 표면에 흡착된 일부 유기 종들을 배출시켜 촉매능을 53% 회복시켰다.

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Development of CAM Automation Module(E-ICAM) for 5-axis Machining of Impeller (A Study on Configuration of Module) (임펠러의 5축 CAM 자동화 모듈(E-ICAM)의 개발 (모듈 구성에 관한 연구))

  • Jung, Hyoun-Chul;Hwang, Jong-Dae;Jung, Yoon-Gyo
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.10 no.4
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    • pp.109-114
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    • 2011
  • An impeller is difficult to machine because of severe collision due to the complex shape, overlapping and twisted shape that form impeller blades. So, most CAM software companies have developed CAM module for manufacturing impeller in addition to their CAM software. But it is not still easy for inexperienced users to machine impellers. The purpose of this paper is the development of automatic CAM module for manufacturing impeller(E-ICAM) which is based on visual basic language and it is used CATIA graphical environment in order to be easily machining impellers. Automatic CAM module for manufacturing of impellers generates tool path, and proposes recommended cutting condition according to the material of stock and tool. In addition, it has also included a post processor for 5-axis control machining. Therefore the user can easily machine impellers using this automation module.

A Study on the Reverse Engineering and Performance Test in the Development of Screw Flowmeter (스크류유량계 개발에서의 역공학 및 성능평가에 관한 연구)

  • Hwang, Jong-Dae;Jung, Jong-Yoon;Lee, Sang-Ryul;Jung, Yoon-Gyo
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.4 no.2
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    • pp.24-30
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    • 2005
  • This research presents a modeling and a manufacturing method of screw flow meter. This paper introduces the efficient design and manufacturing method of screw type flow meter using reverse engineering and test technology. The methods introduced this paper utilize the reverse engineering that is increasing accuracy of modeling and manufacturing of reverse model. And then it can be used in performance test with hydraulic test equipment. Hence this can be used in the basic document for development of the quite accurate flowmeter.

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Mold Quality Improvement through Overlay Welding (육성용접을 통한 금형 품질 향상에 관한 연구)

  • Yun, Il-Woo;Hwang, Jong-Dae
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.19 no.4
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    • pp.52-57
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    • 2020
  • The frequency of the manufacturing and modification of automotive press dies via overlay welding has recently increased, but the welding quality depends on the operator skills and the working conditions. Therefore, this study presents a way to improve the overlay welding quality regardless of the operator skills. Three welding conditions with different pre- and post-heating treatments were tested on some specimens; the weld surface quality was analyzed by examining the cutting face. The results demonstrated the best quality of the weld surface that was heated before and after the welding.

A Study on the Application of Reverse Engineering for Impeller using Polynomial Regression (다항식회귀곡선을 통한 임펠러의 역공학 적용에 관한 연구)

  • Hwang J. D.;Jung J. Y.;Jung Y. G.
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.13 no.5
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    • pp.103-109
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    • 2004
  • This paper presents a fairing method for reverse engineering of a free-formed surface. Utilizing measured data points, reverse engineering is a useful method to construct a CAD model from physical model. Measured data points should be faired since raw data may have outliers. A fairing algorithm of polynomial regression model generates smooth curves of approximation in this paper. The faired curves are utilized to construct a free-formed surface. For a verifying example, an impeller blade is digitized with a CMM to collect raw data on the surfacce and a CAD model is constructed. This research produces impeller blades with 5-axis machining center through the CAD model and compares them with a physical model. As a result the produced surface modeled with the fairing method gives less error than that without the fairing.