• Proceedings of the Korea Contents Association Conference
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• 2007.11a
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• pp.188-192
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• 2007

Today, the most pivotal issue in the national research and development, and national scientific and technical policy is to overcome uncertainties in the environment of technology development. The social and economic environment around us is at restricted uncertainty (complex system) where order and disorder coexist. Furthermore, the environment of technology development is more complicated. In order to bring about creativity in practices of technology development, we need a paradigm shift towards a new framework for the construction of the national scientific and technical information infrastructure, which entails a shift to creativity, self-organization and dynamic capability. The paradigm shift will lead the present scientific and technical information infrastructure which centers on information sharing, to move towards one that enables information coherence through self-organization. Thus, it is expected that the new Web 3.0 will provide a client-flexible analysis information system that will make information coherence and feedback possible. Through this system, the policy for the construction of a new scientific and technical infrastructure will evolve, which will bring about co-evolution of individual's knowledge through sharing of self-organizaed knowhow.

• Applied Microscopy
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• v.34 no.1
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• pp.1-11
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• 2004

The wound healing is very complex biological processing including inflammatory, reepithelialization and matrix construction. According to the biological systematic category, the ability of the healing is very different. Generally healing ability of the lower animal group has been known more excellent compared to its higher group. Therefore, lower animals have been used as the experimental model to explore the mechanism of the wound healing or repair. To verify histochemical characteristics of the wound healing, we have used skin of the frog (Bombina orientalis) as known common amphibian. At day 1, 10, and 16, the mucous substance was very actively synthesized and strong positive by PAS and Alcian blue (pH 2.5). Day 10 after wounding, margin of the wound was gradually strong positive by PTAH staining for detection of collagen synthesis. At 3 to 6 hour and day 23 to 27, we have found the cell division was active through the MG-P staining, in which the concentration and division of DNA in nucleus was green to deep blue color.

• Management & Information Systems Review
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• v.35 no.4
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• pp.185-211
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• 2016

This study examined the impact of learning organization activities on burnout and the moderating effect of supervisor trust in a learning organization. The results of the study shows that among the activities of a learning organization, independent variables in this study, promoting inquiry and dialogue as well as encouraging collaboration and team learning affect burnout. In other words, the dedication of an organization to creating a culture in which various learning approaches are experimented through questioning and giving feedback as well as collaborative learning that can reinforce the effective use of team resources have an impact on reducing emotional exhaustion, which is considered to be at the core of burnout. Plus, these factors reduce impersonalization, which is activated to prevent further emotional exhaustion by dealing with customers, colleagues and jobs in a cold, negative and perfunctory way. In this study, the dimensions of promoting inquiry and dialogue as well as encouraging collaboration and team learning were found to reduce the decline in personal sense of achievement of an employee with a negative assessment of himself or herself derived from a lack of achievement in his or her job. Supervisor trust (integrity, benevolence and ability) had a moderating effect on the relationship between strategic learning leadership and impersonalization/emotional exhaustion. This suggests that the trust of supervisor helps mediate and moderate the emotional exhaustion and impersonalization of organizational members by encouraging leaders to drive change and take the organization to a new direction. The study has provided implications that communication plays an important role in reducing burnout in the learning context such as positive, appreciative inquiry and feedback analysis to identify strength, and that supervisor trust is critical in order to ensure strategic learning leadership exerts greater influence on the organization.

• Journal of Life Science
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• v.29 no.11
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• pp.1258-1266
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• 2019

Yangkyuksanhwa-Tang (YKSH), consisting of nine different herbs, is commonly used in Soyangin-type individuals with stroke, based on the Sasang Constitution Theory in Korea. However, no evidence has yet confirmed a beneficial effect of YKSH in ischemic stroke treatment. In this study, we investigated the effects of YKSH on ischemic brain injury in a mouse model of cerebral ischemia. Focal cerebral ischemia in mice was induced by photothrombosis, and behavioral recovery was evaluated. Infarct volume, inflammation, and newly generated cells were evaluated by histology and immunochemistry. YKSH treatment resulted in a significant recovery from the motor impairments induced by focal cerebral ischemia, as determined with wire grip and rotarod tests. YKSH treatment also decreased the infarct volume and the number of cells positive for tumor necrosis factor-${\alpha}$ and myeloperoxidase when compared with a vehicle-treated control group. By contrast, YKSH treatment considerably increased the number of cells positive for glial fibrillary acidic protein and ionized calcium-binding adapter molecule 1, as well as the number of cells doubly positive for Ki67/doublecortin when compared with the vehicle-treated group. These results suggest that YKSH treatment attenuated the infarct size by anti-inflammatory action, astrocyte and microglia activation, and neuronal proliferation, thereby facilitating neurofunctional recovery from a cerebral ischemic assault. YKSH could therefore be a potential treatment for neurofunctional restoration of the injured brains of patients with stroke.

• Journal of Yeungnam Medical Science
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• v.18 no.2
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• pp.253-266
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• 2001

Background: The causes of ADHD(attention deficit hyperactivity disorder) are various, so it is impossible to understand the whole characteristics of ADHD, only with simple intelligence testing scales. We compared cognitive characteristics of ADHD group with normal controls with Korean Kaufman Assessment Battery for Children(K-ABC). It is well known to evaluate neuropsychological and cognitive aspects of the children. Materials and Methods: Age and sex matched 40 ADHD patients and 40 normal controls tested with the K-ABC. Each subscales compared between pre-treatment patients and controls, pre-treatment and post-treatment in patient group, post-treatment patients and controls. Results: Significant differences are observed in sequential processing, simultaneous processing, cognitive processing and achievement between pre-treatment patients and controls, and in gestalt closure between pre-treatment and post-treatment patients group. But there are no significant differences between pre-treatment patients and controls in gestalt closure and reading/decoding. Conclusions: Methylphenidate improved the scores of simultaneous scale, which means improvement of executive functions such as divided attention, analysis and organization. Methylphenidate also reduced distractibility.

• The Journal of Engineering Geology
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• v.4 no.1
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• pp.43-55
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• 1994

Two thematic maps on environmental geology were produced in the Cheong-Ju area, with aids of GIS technique. They are landslide hazards & risk maps and cut-fill maps. The models of environmental geology map and digital database were established for creation of these maps by means of cartographic simulation in GIS. These special maps are very important for understanding the environmental characteristics of the study area, and can be applied in the establishment of the regional land use planning. For instance, the landslide hazard and risk map can play very important role in the road design, and cut- fill map in the construction work in the area. The scoring system for landslide analysis was developed through the evaluation of each environmental geologic factor in relation to the others and reflects the relative imporatance of each factor. The excavation index(easy, intermediate and difficult) was evaluated through cut-fill analysis, and they can be very useftil for assessing the degree of excavation difficulty.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.6 no.7
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• pp.1026-1031
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• 2002

In this Paper, We analysed the technical characteristics of a automatic identification system that will introduce in aviation and marine radio stations. IMO's Marine Safety Committee approved revision of chapter V of the Safety of Life at Sea(SOLAS) Convention in 73rd meeting. According to this, AIS will become a mandatory carriage requirement by 01 July 2002. AIS as a surveillance system continuously receives its own position from the GNSS and then repeatedly broadcasts it on a W:.u data link for avoiding traffic conflicts and possible disasters. VHF data link is organized so that a specified number of time slots make up a repeatable frame. Each radio station can autonomously allocate and deallocate slots within the frame using selection algorithm which is called SOTDMA(Self-Organized Time Division Multiple Access). The results can be an aid in the continued of understanding technical characteristics for AIS as a broad surveillance system.

• Journal of the Korea Society of Computer and Information
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• v.18 no.7
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• pp.93-100
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• 2013

The ensuing disaster brought by the massive earthquake and tsunami in the northeastern region of Japan in 2011 placed Japan, one of the three most advanced economic powers in the world, in a defenseless state. With the rising interest in disaster recovery, Korea is also making efforts to provide technological support for barrier-free system operation 24 hours a day, 365 days a year. To protect intelligence assets efficiently, this study draws a job performance plan to prepare for disasters, which systemizes methodical coping capabilities into business plans when disasters occur. Moreover, this study systemizes the job performance plan to allow members easy access to information that will help them proceed without confusion in emergencies. This plant is intended to protect intelligence assets of an organization clearly and promptly.

• Journal of the Economic Geographical Society of Korea
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• v.9 no.1
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• pp.7-22
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• 2006

This study examines the mud-based cosmetic business by the City of Boryeong, as a case of commodifying a locality's endowment or assets for local development. Concretely, the study discusses current status, history, and challenges of the business, which is an integral component of the key industry Boryeong seeks to promote by using mud materials. The discussion also encompasses the factors behind the development of the business. From the discussion, my work presents the business‘s implications for the commodification of local endowment/assets and promotion of relevant key industries that not a few localities across Korea pursue for their development. I deal with such implications, primarily in terms of the local institutional capacity that induces the consistent participation and cooperation from a wide variety of stake-holder as well as the shared vision among such stake-holders in order to enable a locality to effectively use its endowments/assets for local development. And this work reiterates that the institutional capacity which is significant for local development has to be analyzed in depth and such an analysis should produce codified knowledge which can function as guidances or manuals for many localities.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.96-96
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• 1993

간부분 절제술을 하지 않는 비수술적 방법으로서 D-galactosamine을 이용한 중기발암성 시험의 개발을 목적으로 F344 수괵 랫드를 이용하여 본 실험을 수행하였다. 실험 I 에서는 실험방법에 따라 3가지 모델로 구분하고, 각 모델에 처치군과 대조군을 두었다. 모델 1 에서는 실험개시시에 diethylinitrosamine (DEN)을 200 mg/kg body weight로 복강내로 1회 투여하고, 실험개시후 2및 5주에 D-galactosamine을 300 mg/kg body weight로 복강내로 각각 1회 투여하였다. 처치군에는 실험개시후 2주부터 6주간 2-acetylaminofluorene을 0.01%로 혼합한 사료를 급여하였으며, 대조군에는 기초사료를 계속 급여하였다. 모델 2에서는 모델 1의 4주차까지의 처치를 2회 반복하였다. 모델 3은 간부분 절제술을 하는 DEN-PH (diethylnitrosamine-partial hepatectomy) 모델과 같은 방법으로 처치하였다. 사육기간 중 매주 체중 및 사료소비량을 측정하였고, DEN 투여후 8주에 전동물을 부검하여 적출한 간의 중량을 측정하고, glutathione S-transferase placental form (GST-P) 양성 foci에 대한 면역조직화학적 염색표본을 만들어 GST-P 양성 foci의 수 및 면적을 측정하였다. 실험 II에서는 모델 1의 방법으로 phenobarbital(PB), 3-methylcholanthrene (3-MC), n-ethyl-n'-nitro-n-nitrosoguanidine 및 3,3'-diaminobenzidine외 GST-P 양성 foci의 발현정도를 조사하였다. 실험 I의 결과, 모델 1이 정상적인 체중 증가를 보여주었으며, 간조직의 GST-P 양성 foci 의 발현율이 가장 좋았다. GST-P 양성 foci의 면적은 큰것 부터 미상엽, 내측우엽, 외측우엽의 순으로 나타났으나 foci의 수는 모델별로 다르게 나타났다. 실험 II의 PB 투여군과 3-MC 투여군에서 GST-P 양성 foci의 수 및 면적의 유의성 있는 증가가 관찰되었다. 이와 같은 결과로 볼때, 비수술적 방법인 D-galactosamine 을 이용한 중기 발암성 검색법은 간부분 절제술을 이용한 중기발암성 검색법에 비하여 GST-P 양성foci의 발현능력이 동등하거나 더 우수하였으며, 간 및 간이외 장기의 발암물질에 대한 발암성 검색에 보다 유용할 것으로 생각된다.