• Title/Summary/Keyword: 조직의 변화가능성

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Effect of Juvenile Hormone Analogue(JHA) on the Adult Development of the Silkworm, Bombyx mori (유약호르몬류 투여가 누에 성충화 발육에 미치는 영향)

  • Seong, Ju-Il;Im, Bong-Hak;Gang, Hyeon-A
    • Journal of Sericultural and Entomological Science
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    • v.35 no.1
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    • pp.28-35
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    • 1993
  • Treatment of juvenile hormone analogue(JHA) at the 5th instar larvae prolonged the duration of adult development one to one and half days as well as the elongation of feeding time with the increasing of larval body weight. Morphological observation and protein analysis in hemolymphs, integuements, alimentary canals, fat bodies and ovaries also revealed that the development of these tissues and organs for adultation are affected by the JHA treatment.

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Application of Endometrial Biopsy in the Horse (말에서의 자궁내막생검)

  • Yong, Hwan-Yul
    • Journal of Veterinary Clinics
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    • v.24 no.2
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    • pp.292-294
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    • 2007
  • Endometrial biopsy in the horse is an important technique for maintaining breeding soundness by detecting changes related with reduced fertility and monitoring response to specific uterine therapy. A 13-year-old thoroughbred mare had been in trouble with repeated breeding for getting pregnant before the sample of endometrial biopsy was offered to investigate the possibility of pregnancy in the future. Based on the tissue sections examined, the prognosis for this mare to conceive and successfully carry a foal to term was estimated to be 10 to 50%.

The Mediating Effects of Self-efficacy on the relationship between Job-stress and Depression (지역 의료기관 행정직 직장인의 자기효능감 -직무스트레스와 우울에 미치는 매개효과를 중심으로)

  • Kim, Hye-Sook
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.10
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    • pp.5069-5077
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    • 2013
  • The purpose of the study was to identify the mediating effects of self-efficacy between job-stress and depression in regional hospitals' workers. The data of this study were collected from 700 hospitals' workers who have been working in 306 hospitals in B city. And the data were collected from Feb. to May 2012. To determine the impact of self-efficacy on job-stress and depression for men and women workers in local hospitals, we measure self-efficacy, job-stress and depression of workers and analyze their relationships. There was a negative relationship between self-efficacy and job-stress(r=-.238, p<.001), depression(r=-.626 p<.001). Verifying the mediating effects of self-efficacy to the impact of job stress on depression, the mediating effects of self-efficacy were significant. It suggests that there is a need to relax the negative impact of job stress through the promotion of self-efficacy for individual or team-level organization.

Toxicity of 30 kGy Irradiated Cereal Powders for Three Months (30 kGy 감마선 조사된 곡류 분말의 아급성 독성평가)

  • Jeon, Young-Eun;Kim, Hye-Mi;Lee, Ju-Woon;Byun, Myung-Woo;Kang, Il-Jun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.10
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    • pp.1264-1270
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    • 2008
  • In order to evaluate their possible subacute toxicity, the male and female of SD rats were given to 30 kGy irradiated cereal powders for three months. During the experimental periods, appearance, behavior, mortality, body weight, organ weight, and food consumption of rats fed the 30 kGy cereal powders were not affected compared to the non-irradiated control. In urine analysis, histopathological examination, hematological as well as in serum biochemical findings, no significant differences were found between the rats administered with non-irradiated control and 30 kGy cereal powders for three months. These results indicate that cereal powders irradiated at 30 kGy did not show any toxic effects under these experimental conditions.

Content Distribution Strategy Analysis of Regional Broadcasting Companies: Based on MBCNET (지역방송의 뉴미디어 유통전략 분석 :MBCNET 사례를 중심으로)

  • Kim, Jongha Bell
    • The Journal of the Korea Contents Association
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    • v.13 no.11
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    • pp.636-643
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    • 2013
  • The current media and content situation is increasingly more competitive and under the radical environment changes, the social & financial position of regional broadcasting companies has been threatened. The internet & mobile based platforms and smart media, however, bring a new opportunity of content distribution. This study analyzes the current status of MBCNET which is the superstation of regional MBC stations and specialists interviews to develop the content distribution strategies of regional broadcasting companies. According to the following: finance, ratings, and new media distribution analysis, the MBCNET outcome is deemed successful based on the content library and regional power. MBCNET utilized opportunity to develop strong content resources and distribution power. In order to maintain its competitive edge, MBCNET needs to adopt the following strategies: content and platform marketing power, research & development of competitive content based on user behavior analysis, and reorganization that is able to counteract N-screen circumstances.

Decreased of Clusterin mRNA Expression of Epididymis Following Exposure to Bisphenol A Diglycidyl Ether during Gestation and Lactation in Sprague-Dawley Rats (임신 및 수유기간 동안 Bisphenol A Diglycidyl Ether 노출에 의한 랏트 부고환 clusterin mRNA 발현량 감소)

  • Kang, Dae-Woong;Kwon, Su-Kyoung;Yang, Yun-Jung;Chun, Young-Jin;Hong, Yeon-Pyo
    • Environmental Analysis Health and Toxicology
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    • v.23 no.4
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    • pp.291-299
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    • 2008
  • Bisphenol A diglycidyl ether(BADGE)는 비스페놀 A와 에피클로로하이드린의 축합에 의해 만들어지는 물질로 상업용 액상 에폭시 수지의 주성분이다. 본 연구는 clusterin mRNA 발현이 BADGE의 노출된 생식기계 독성에 연관되어 있는지를 연구하기 위해 수행하였다. BADGE는 SPF Sprague-Dawley 임신 랏트에 임신 6일부터 수유기가지 하루에 한 번 0(대조군)과 375mg/kg/day를 경구 투여하였다. 수컷 새끼는 일반 사항과 몸무게, 일반 발달 지표(예, 항문과 생식기 사이의 거리, 이개개전, 절치붕출, 유두잔류, 안검개열, 고환하강, 포피박리 등)등을 관찰하였다. 대조군과 투여군에서 다섯 마리의 수컷 새끼는 출생 후 3, 6와 9주에 부검하여 부고환의 조직학적 변화 등을 관찰하였다. BADGE 375 mg/kg/day 투여군에서 항문과 생식기 사이의 거리는 대조군보다 길어지는 경향을 보였다. 출생 후 6주와 9주에서 부고환의 상대 무게는 대조군보다 약간 증가하였으나 조직학적인 변화는 관찰되지 않았다. BADGE 투여 군에서 clusterin mRNA 발현량은 대조군에 비해 3주에 56%, 6주에 57% 그리고 9주에 86% 감소하였다. 이런 결과는 랏트의 부고환에서 clusterin은 BADGE에 반응하는 유전자 중 하나일 수 있다는 가능성을 나타낸다.

Effect of Salviae Radix on renal tubular reabsorption in rabbits with mercury-induced acute renal failure (수은으로 유발된 토끼의 신장 기능 손상에 대한 단삼(丹參)의 효과)

  • Hwang, Young-Geun;Jeong, Ji-Cheon
    • The Journal of Internal Korean Medicine
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    • v.21 no.2
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    • pp.227-234
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    • 2000
  • 독성약물에 의한 급성신부전시 세뇨관세포의 물질 재흡수 장애에 대한 단삼(丹參) 추출액의 효과를 조사하였다. 토끼에 수은(HgCl2)을 10 mg/kg되게 피하 주사하여 급성신부전을 유발하였고, 단삼(丹參) 추출액의 효과는 수은을 주사하기 전 7일 동안 0.05% 액(液) 0.3 g/kg 용량을 경구 투여하여 관찰하였다. 수은을 주사하기 전 24시간 동안 요와 혈액을 채취하여 신장기능을 측정하여 대조기간(basal period)의 값으로 하였고, 수은을 주사한 후 24시간 동안 요와 혈액을 얻어 수은에 의한 신장기능 변화를 평가하였다. 수은을 처리한 후 사구체여과율이 대조값에 비해 감소하였고, 혈청내 creatinine 농도가 증가하였다. 이러한 결과들은 수은이 급성신부전을 유발하였음을 가리킨다. 수은을 처리한 동물에서 포도당 및 인산의 배설분율이 증가하였고, 이러한 변화는 brush-border membrane에서 물질의 이동장애와 Na-pump 활성의 감소에 기인하였다. 수은을 주사한 동물의 신장피질 절편에서 유기이온인 PAH와 TEA 이동이 억제되었다. 토끼의 신장조직에서 지질의 과산화가 수은을 주사한 후 증가하였다. 단삼(丹參) 추출액을 전 처리한 후 수은을 주사한 경우 수은에 의해 유발된 사구체여과율의 감소와 혈청내 creatinine 농도 증가 현상이 유의하게 완화되었다. 수은에 의한 세뇨관에서 물질의 재흡수 장애가 단삼(丹參) 추출액의 전처리에 의해 방지되었다. 단삼(丹參) 추출액은 수은에 의한 지질의 과산화를 억제하였다. 수은에 의한 급성신부전은 항산화제로 잘 알려진 DPPD에 의해 방지되었다. 이상의 결과를 종합하면 생체실험결과 수은에 의한 급성신부전의 유발과정에 지질의 과산화가 중요한 역할을 할 가능성을 보이고 있고, 단삼(丹參) 추출액은 수은에 의한 급성신부전을 방지하는 효과를 가지고 있으며, 그 효과는 단삼(丹參)의 항산화작용에 기인(起因)할 가능성이 많다.

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Biocompatibility of Biodegradable Films by Natural Polymers (천연고분자 분해성 필름의 생체적합성 연구)

  • Hwang, Sung Kwy;Lee, Ki Chang;Rhim, Kook Hwan
    • Applied Chemistry for Engineering
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    • v.10 no.6
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    • pp.939-943
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    • 1999
  • Recently there has been an explosion of interest in the topic of biodegradable polymers for medical applications. In this study, films were prepared by solution casting method using natural polymers (xanthan, locust bean, guar gum, chitosan and algin) as biomaterials. Biocompatibility of films prepared from natural polymer as a skin implant was evaluated. These biodegradable films were subcutaneously implanted in the back of rats and their biodegradability was investigated by the evaluation of changes in structure, film weight and hematology as a function of time for the biotransformation. The result of rats test showed that locust bean and guar gum induced some suspects of non-biocompatibility in the tissue by foreign body reaction 24 and 48 hrs after implantation. These results showed the potential of partial biodegradable films prepared from natural polymer for ideal skin biomaterials at short period.

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An Exploratory Study on Regulatory Agencies' Behaviors Responding to Regulatory Resource Constraints (규제자원 제약에 대한 규제기관의 대응행태에 관한 시론적 연구)

  • Im, Jae Jin
    • Journal of Regulation Studies
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    • v.27 no.2
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    • pp.71-104
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    • 2018
  • Regulatory agencies' response to resource constraints is an important issue in terms of regulatory effectiveness, but systematic research is lacking. As an effort to overcome this limitation, this study was to explore behaviors of regulatory agencies in response to resource constraints. Reviewing the precedent studies based on regulatory and organizational theories, the study suggested the potential behaviors of regulatory agencies under resource constraints: changes in regulatory processes, changes in enforcement methods, decoupling, and regulatory delegation and contracting-out. The study also discussed the realistic explanations of the response behaviors partly through the case of marine transportation regulation, and explained the problems that the regulatory agency's behaviors could bring about. Based on the findings, the study suggested that the regulatory framework should be designed to ensure the effectiveness of the regulatory system in consideration of the regulatory agencies' behaviors under resource constraints. The study is expected to contribute to developing a theoretical analysis framework ultimately for an empirical study in the future.

Typology Study on Journalists' Barriers to Science Reporting: Focusing on Q methodology (언론인들의 과학보도 장벽 유형에 관한 연구 - Q 방법론을 중심으로)

  • Kim, Jin-Young
    • Korean journal of communication and information
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    • v.49
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    • pp.99-121
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    • 2010
  • Utilizing Q methodology, this study explored typology on journalists' barriers to science reporting. Two research issues were raised: First, what are the subjectivity factors and characteristic feature of journalist's barriers to science reporting; Second, what are the commonalities and differences among them. 20 science journalists were interviewed in-depth to find out their subjectivity factors. Korean journalists' type of barriers to science reporting could be classified into 4 groups as follows: Type I(N=8) is "reporting tendency barrier" type. Type II(N=3) is named for "institutional and systematic framework barrier". Type 3(N=5) belongs to "situational barrier" type. Type 4(N=3) is "scientific knowledge barrier" type.

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