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Effect of Visual Sensory Improvement by Amblyopia Treatment on Improvement of Ocular Functions (약시 치료에 의한 시감각 개선이 안기능 향상에 미치는 효과)

  • Kim, Jae-Do
    • Journal of Korean Ophthalmic Optics Society
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    • v.19 no.4
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    • pp.551-555
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    • 2014
  • Purpose: This study is to investigate if the improvement of visual sensory (VS) by amblyopia treatment affects the ocular functions in refractive errors, accommodative errors and phoria at distance and near. Methods: 10 subjects (17 eyes, mean age of $10.7{\pm}2.9$ years) who treated amblyopia completely, were participated for this study. Refractive errors, accommodative errors, and distance and near phoria were compared between before and after treatments of amblyopia. Refractive errors and accommodative errors at 40 cm were measured using openfield auto-refractor (NVision-5001, Shin Nippon, Japan) and using monocular estimated method (MEM) respectively. Phoria was determined at 3 m for distance and at 40 cm for near using Howell phoria card, cover test or Maddox rod. Results: Mean corrected visual acuity (CVA) significantly increased from $0.46{\pm}0.11$ (decimal notation) for before amblyopia treatment to a level of $1.03{\pm}0.13$ for after amblyopia treatment (p < 0.001). For spherical refractive error, hyperopia significantly decreased from $+2.29{\pm}0.86D$ to a level of $+1.1{\pm}2.38D$ (p < 0.05) but astigmatism did not significantly change; $-1.80{\pm}1.41D$ for before treatment and $-1.65{\pm}1.30D$D for after treatment (p > 0.05). Accommodative error significantly decreased from accommodative lag of $+1.1{\pm}0.75D$ to a level of $+0.5{\pm}0.59D$ (accommodative lag) (p < 0.05). Distance phoria significantly changed from eso $2.9{\pm}6.17PD$ (prism diopters) to a level of eso $0.2{\pm}3.49PD$ (p < 0.05), and near phoria also significantly changed from eso $0.4{\pm}2.32PD$ to level of exo $2{\pm}4.9PD$ (p < 0.05). There was a high correlation (r = 0.88, p < 0.001) between improvement of visual acuity and decrease of accommodative lag. Conclusions: Hyperopic refractive error decreased with improvement of CVA or VS by amblyopia treatment. And the improvement of VS by amblyopia treatment also improved accommodative error, and changed phoria coupled with accommodation.

ORAL HEMORRHAGE CONTROL AS TREATMENT PRIORITY IN A MENTALLY RETARDED PATIENT WITH MULTIPLE TRAUMA (다발성 손상을 가진 정신지체 환자에서 치료 우선순위로 구강출혈의 조절)

  • Oh, Ji-Hyeon;Kim, Ji-Hun;Yoo, Jae-Ha
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.12 no.1
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    • pp.20-26
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    • 2016
  • Sympathetic reaction to grotesque facial injuries with oral bleeding can trigger confusion and generate inefficiency among emergency room personnel. Regardless of the extent of the injury, or of the sympathy elicated, the victim must be evaluated and treated as a whole patient with multiple trauma. There must be no confusion as to order of importance in the steps of evaluation : 1. airway 2. hemorrhage 3. shock 4. associated injuries 5. local injury 6. triage of facial injuries. The most dangerous aspect of oral hemorrhage is the possibility of its obstructing the upper airway. Swallowing large amounts of blood will usually cause gastric irritation and lead to vomiting, thus further complicating the management of the patient. Once a clear airway is assured and hemorrhage have been controlled, consideration is given to possible associated injuries before undertaking treatment of the facial injuries themselves. Status of the cardiopulmonary, gastrointestinal and neuromuscular systems all have a bearing on decisions concerning facial injury treatment. In this light, treatment priority becomes exceeding important. On the other hand, the importance of facial injuries should never be minimized, especially in a mentally retarded patient with oral hemorrhage. This is a case report about oral hemorrhage control as treatment priority in a mentally retarded patient.

A Study about Measurement Method for Quantitative Classification of Breeding Pig's Locomotor Behaviors using Ultrasonic Sensor Array (초음파 센서 어레이를 이용한 모돈 지제이상 정량분석 방법 연구)

  • Cho, Jinho;Oh, Jong-woo;Lee, DongHoon
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 2017.04a
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    • pp.163-163
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    • 2017
  • 모돈은 교배, 임신, 분만, 포유, 이유를 순환적 반복을 요구하는 개체로서 스마트 농장 시스템의 생산성 향상에 있어서 중요한 요소이다. 본 연구에서는 모돈 능력의 극대화 및 최적의 시스템 관리를 위해서 초음파 센서를 활용한 모돈의 지제 이상 징후를 실시간으로 계측할 수 있는 시스템을 개발하였다. 이 시스템은 높이에 따라 상-중-하(30 cm 간격), 위치에 따라 전면부-후면부에 초음파 센서를 설치하고 이를 마이크로 컨트롤러에 연결하여 모돈의 지제 이상 유무 측정이 가능하도록 하였다. 모돈의 체형과 위치를 고려하여 설치된 초음파 센서의 위치 조절이 가능하도록 하였다. 또한 소형 LCD 모듈을 내장하여 실시간 모니터링이 가능하도록 하였으며, 측정된 데이터는 저장장치인 microSD 카드에 저장되도록 하였다. 모돈사의 환경을 고려하여 방밀형 구조로 하우징 마감하였다. 이 모돈 지체 이상 분석 시스템에 사용된 툴은 C언어를 이용하였다. 건강한 모돈을 대상으로 모돈의 지제의 관찰을 위하여 총 12회의 현장 실증실험이 수행되었으며, 현장 실증 시험 중 소요된 시간은 현장의 상황에 따라 다소 상이하였다 (8시간-28일). 높이 상에 위치한 전면부 및 후면부 초음파 센서 모두에서 모돈이 검출이 된 경우 정상 기립으로 간주하였고, 높이 상에 위치한 전면-후면부 초음파 센서 모두에서 모돈이 검출이 되지 않은 경우 정상적으로 누워 있는 걸로 간주하였다. 높이 하에 위치한 전면부 혹은 후면부 초음파 센서 한곳만 모돈이 검출된 경우 비정상적인 기립으로 간주하였다. 취득된 데이터를 분석한 결과 모돈의 정상적 상태 (기립상태, 누운 상태, 앉은 상태)와 그 외의 비정상적 상태로 분류가 가능하다. 또한 측정된 초음파 센서의 진동의 유무 및 파동형태에 따라서 모돈의 상태 예측이 가능하다. 초음파 센서의 진동 파동이 크고 안정된 상태인 경우 정상적인 활동 상태로 판단하였으며, 진동 파동이 작고 안정적인 경우는 수면 상태로 분류하였다. 실시간으로 지속적인 데이터 획득을 위하여 차후 초음파 센서 및 시스템의 보완작업이 필요하다. 이와같은 모돈의 행동 패턴에 따른 취득된 데이터를 분류하여 모돈의 발정에 의한 행동 특성(기립시간) 분석에 따른 발정 적기 발견 및 정량화 기술 개발에 활용이 가능하다.

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Production and Developmental Pattern of Embryogenic Callus in Oenanthe javanica ($B_{L.}$) DC. (미나리 체세포 배발생 캘러스의 획득과 발달 형태)

  • Gab Cheon KOH;Chang Soon AHN
    • Korean Journal of Plant Tissue Culture
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    • v.22 no.5
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    • pp.283-290
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    • 1995
  • This experiment was canted out to obtain embryogenic callus and to understand developmental mechanism of somatic embryogenesis in Oenanthe javanica ($B_{L.}$) DC. experiments included the examination of explant source and media for embryogenic callus production and the observation of developmental pattern of embryogenic cells and non-embryogenic cells. Embryogenic calli were formed on zygotic pro-embryos together with their endosperms when they were cultured on Ms media containing 1.0mg/L 2,4-D. Embryogenic calli were also formed on the intact surface in vitro grown stem or petiole segmentsafrer 6-8 weeks of culture, whereas non-embryogenic calli were formed on cut surfaces of the stem and petiole after 2 weeks of culture. Non-embryogenic calli were rhizogenic in suspension and solid media culture.

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The Effect of Single-Entry Metering and Platoon Metering on Mainstream under the Same Metering Rate with Pre-timed Metering (정주기식 동일 미터링율 제어에서 차량진입방식에 따른 효과분석)

  • Kim, Sang-Gu;Ryu, Ju-Hyeon
    • Journal of Korean Society of Transportation
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    • v.28 no.3
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    • pp.29-37
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    • 2010
  • Ramp metering control is the most representative strategy of uninterrupted flow control and management system. Ramp metering is to adjust vehicles entering an expressway in such a way that expressway mainline maintains flow stability by regulating ramp vehicles. The effect of two metering strategies, single-entry metering and platoon metering, on mainstream under the same metering rate with pre-timed metering are analyzed by micro-simulation. Platoon metering shows lower performance than single-entry metering under the same metering rate in terms of speed, density, and delay, causes earlier breakdown than single-entry metering. It indicates that the selection of metering type has critical importance as the flow of mainline is high.

Development of intracellular organelle markers using modified glycolipid-binding peptides in mammalian cells (세포내 특정 소기관 타기팅 마커 개발을 위한 당지질-결합 펩타이드 변형 및 세포내 타기팅 분석)

  • Jun, Yong-Woo;Lee, Jin-A;Jang, Deok-Jin
    • Analytical Science and Technology
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    • v.28 no.1
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    • pp.65-71
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    • 2015
  • Intracellular organelles in eukaryotic cells play important roles in many cellular functions. Intracellular trafficking of many proteins to specific intracellular organelles is tightly regulated by various mechanisms in cells. Therefore, elucidating the targeting mechanism of novel markers for intracellular organelles is important for cellular physiology and pathology. In this study, we tried to identify the peptides which could bind to specific glycolipid in cellular membrane using GFP-fused glycolipid-binding peptides, and analyzed their cellular localization. As a result, we could identify mitochondria-, Golgi- or plasma membrane-targeting peptides. Furthermore, we found that the plasma membrane-targeting peptide was localized to the plasma membrane via electrostatic interactions. Thus, our results suggest that various glycolipid-binding peptides could be used as intracellular organelles markers.

Effect of Graphite Nanofibers Addition on the Electrochemical Behaviors of Platinum Nanoparticles Deposited on Activated Carbons (활성탄소에 담지된 백금나노입자의 전기화학적 거동에 대한 그라파이트 나노섬유 첨가효과)

  • Jo, Wonbin;Oh, Misoon;Kim, Juhyun;Kim, Seok
    • Korean Chemical Engineering Research
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    • v.48 no.6
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    • pp.673-678
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    • 2010
  • In the present study, mixed carbon-supported platinum(Pt) nanoparticles were prepared by a chemical reduction method of Pt precursor solution on two types of carbon materials such as activated carbons(ACs) and graphite nanofibers(GNFs). Average crystalline sizes and loading levels of Pt metal particles could be controlled by changing a content of GNFs. The highest electroactivity for methanol oxidation was obtained by preparing the carbon supports having 15 wt% GNFs. Furthermore, with an increase of GNFs content from 0% to 15%, an electrical conductivity was changed from $10^{-4}S/cm$ to $10^{-1}S/cm$. By an introduction of 10 wt% GNFs additive, the electroactivity of platinum particles was enhanced, but was saturated in the case of 15 wt% GNFs contents. This was related with the fact that the electroactivity change was dependent on the electrical conductivity of mixed carbon supports and Pt particle deposition content or deposition morphology.

Enhanced NOW-Sort on a PC Cluster with a Low-Speed Network (저속 네트웍 PC 클러스터상에서 NOW-Sort의 성능향상)

  • Kim, Ji-Hyoung;Kim, Dong-Seung
    • Journal of KIISE:Computer Systems and Theory
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    • v.29 no.10
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    • pp.550-560
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    • 2002
  • External sort on cluster computers requires not only fast internal sorting computation but also careful scheduling of disk input and output and interprocessor communication through networks. This is because the overall time for the execution is determined by reflecting the times for all the jobs involved, and the portion for interprocessor communication and disk I/O operations is significant. In this paper, we improve the sorting performance (sorting throughput) on a cluster of PCs with a low-speed network by developing a new algorithm that enables even distribution of load among processors, and optimizes the disk read and write operations with other computation/communication activities during the sort. Experimental results support the effectiveness of the algorithm. We observe the algorithm reduces the sort time by 45% compared to the previous NOW-sort[1], and provides more scalability in the expansion of the computing nodes of the cluster as well.

Vici Syndrome with Novel Compound Heterozygous Mutations in EPG5 (EPG5 유전자 변이가 확인된 Vici 증후군 1례)

  • Shin, Jehee;Lee, Hyunjoo;Lee, Young-Mock
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.20 no.2
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    • pp.50-54
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    • 2020
  • Vici syndrome is a rare, autosomal recessive multisystem disorder characterized by agenesis of the corpus callosum, cataracts, cardiomyopathy, hypopigmentation, immunodeficiency, and delayed development. We report the case of a 3-year-old boy diagnosed with Vici syndrome. He initially presented with hypotonia and sucking problem. Whole-exome sequencing identified novel compound heterozygous mutations, namely c.2254C>T (p.Gln752Ter) and c.5511-5518+2 del TATGCAAAGT in the EPG5 gene. The diagnostic challenges can be attributed to the diverse clinical manifestations. Thus, whole-exome sequencing is a useful diagnostic tool for the genetically and clinically heterogeneous Vici syndrome. This is the first Korean report of a patient with Vici syndrome.

Analysis of Turbulent Flow by Location Characteristics of Side Weir inlet in Meandering Channels (사행수로 구간의 횡월류위어 유입구 위치특성에 따른 흐름해석)

  • Yu, Chang Hwan;Shin, Jae Sung;Oh, Yeun Kun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.306-306
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    • 2020
  • 횡월류위어(side weir)는 하천의 수위가 한계수위 이상으로 상승할 경우 본류로부터 저류지나 분수로(distributary channel)로 흐름을 전환하기 위하여 사용하는 수공구조물로 강변저류지나 off-line저류지의 유입부에 흐름방향과 평행하게 설치되어 유량관리 및 전환, 홍수통제, 에너지 소산, 수위조절, 일정 유량의 취수 및 분배, 초과 홍수량의 전환 등의 목적으로 이용되는 구조물이다. 횡월류 위어의 월류 흐름은 일반위어와 같이 위어마루부 직각방향으로 흐르지 않고 본류 흐름특성에 따라 비스듬하게 유입된다. 이러한 흐름특성으로 횡월류위어 월류량은 본류의 하폭, 흐름특성, 위어길이 및 설치위치 등에 따라 각기 다르게 산정된다. 현재 국내에서 진행된 횡월류위어 흐름특성에 관련된 연구는 대부분 직선수로에 집중되어 있으며 사행하천의 흐름특성에 따른 연구는 부족한 실정이다. 금회 연구에서는 3차원 상용프로그램인 FLOW-3D를 이용하여 사행하천구간 유입부 설치위치 특성에 따른 횡월류 위어 유입흐름 특성을 분석하였다. 사행하천 구간 횡월류위어 설치위치에 따른 3차원 흐름해석을 위해 AUTO CAD 프로그램을 이용하여 수로길이 30m, 수로폭 2m의 구형 사행수로를 구성하였고, 횡월류위어 유입부 위치를 20°~120°로 변화시키며 수치모형실험을 수행하였다. 해석결과 수로흐름은 유입부 설치각이 작을수록 상·하류 수위차가 작아지며 유속이 감소하며 설치위치각이 클수록 수로내 평균유속은 증가하는 것으로 확인되었다. 유입부 설치각이 작을수록 방류량이 증가하여 수로내 흐름분리현상 증가하였고 이로인한 지체현상이 발생하는 것으로 확인되었다. 본 연구로 사행하천구간에 횡월류위어가 설치된 경우, 월류량과 수리학적 흐름특성을 해석할 때 3차원 수치모형실험이 유용한 해석도구로 이용될 수 있음이 확인되었다. 이후 수치모형실험이 수공구조물 설계 및 해석 시 참고자료로 이용 가능할 것으로 사료된다.

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