• Title/Summary/Keyword: 조선바이오

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Effects of Operating Parameters on Tetrafluoromethane Destruction by a Waterjet Gliding Arc Plasma (워터젯 글라이딩 아크 플라즈마에 의한 사불화탄소 제거에 미치는 운전변수의 영향)

  • Lee, Chae Hong;Chun, Young Nam
    • Applied Chemistry for Engineering
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    • v.22 no.1
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    • pp.31-36
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    • 2011
  • Tetrafluoromethane ($CF_4$) has been used as the plasma etching and chemical vapor deposition (CVD) gas for semiconductor manufacturing processes. However, the gas need to be removed efficiently because of their strong absorption of infrared radiation and the long atmospheric lifetime which cause global warming effects. A waterjet gliding arc plasma system in which plasma is combined with the waterjet was developed to effectively produce OH radicals, resulting in efficient destruction of $CF_4$ gas. Design factors such as electrode shape, electrode angle, gas nozzle diameter, electrode gap, and electrode length were investigated. The highest $CF_4$ destruction of 93.4% was achieved at Arc 1 electrode shape, $20^{\circ}$ electrode angle, 3 mm gas nozzle diameter, 3 mm electrode gap and 120 mm electrode length.

Immune enhancing activity of Sargassum horneri extracts via MAPK pathway in macrophages (대식세포에서 괭생이모자반 추출물의 MAPKs 기전 통한 면역활성 증가 효과)

  • 김동섭;김민지;성낙윤;한인준;김건;김춘성;유영춘;정윤우
    • Journal of Marine Bioscience and Biotechnology
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    • v.15 no.1
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    • pp.12-23
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    • 2023
  • Sargassum horneri (SH), a brown macroalgae, has medicinal properties. The present study investigated the immune-enhancing effects of SH extract on peritoneal macrophages (PM). The SH significantly increased the production of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and nitric oxide (NO) in PM. It was confirmed that SH significantly increased NO expression through the increase of iNOS protein expression, which is the up-regulation pathway. Additionally, it was determined if SH activates the mitogen-activated protein kinase (MAPK) pathway, an upper regulatory mechanism that influences TNF-α, IL-6, and NO expression. Consequently, SH significantly increased the phosphorylation of p38, extracellular signal-regulated kinases (ERK), and c-Jun N-terminal kinase (JNK), all of which are MAPK pathway proteins. Moreover, the immune-enhancing effects of SH on another macrophage cell line, bone marrow-derived macrophages were investigated. It was observed that SH significantly enhanced TNF-α, IL-6, and NO production. Overall, this study demonstrates the immune-enhancing effects of SH on macrophages via activated MAPK pathway. Therefore, it suggests that SH has the potential to improve immunological activity in various macrophage cell lines and can be useful as an immune-enhancing treatment.

Electrochemical properties of the mugwort-embedded biosensor for the determination of hydrogen peroxide (쑥을 이용한 과산화수소 정량 바이오센서의 전기화학적 성질)

  • Lee, Beom-Gyu;Park, Sung-Woo;Yoon, Kil-Joong
    • Analytical Science and Technology
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    • v.19 no.1
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    • pp.58-64
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    • 2006
  • A mugwort-tissue-based modified carbon paste electrode was constructed for the amperometric detection of hydrogen peroxide and its electrochemical properties are described. Especially the amperometric signal was very stable and bigger than any other enzyme electrode studied in this lab. The effect of tissue composition on the response was linear within the wide range of experiment and the linearity of Lineweaver-Burk plot showed that the sensing process of the biosensor is by enzymatic catalysis. And pH dependent current profile connoted that two isozymes are active in this system.

Partial Oxidation Reformer in a Plasma-Recuperative Burner (플라즈마-축열버너 부분산화 개질장치)

  • AN, JUNE;CHUN, YOUNG NAM
    • Transactions of the Korean hydrogen and new energy society
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    • v.32 no.1
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    • pp.68-76
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    • 2021
  • Climate change problems occur during the use of fossil fuel and the process of biogas production. Research continues to convert carbon dioxide and methane, the major causes of climate change, into high-quality energy sources. in order to present the performance potential for the novel plasma-recuperative burner reformer, the reforming characteristics for each variable were indentified. The optimal operating condition of was an O2/C ratio of 1.0 and a total gas supply of 20 L/min. At this time, CH4 conversion was 64%, H2 selectivity was 39%, and H2/CO ratio was 1.13, which were the results applicable to the solid oxide fuel cell fuel stack for RPG, or Residential Power Generator. Recirculation of reformed gas increases the amount of H2 and CO, which are combustible gases, especially the amount of H2. As a result, the H2 selectivity is improved, and high-quality gas can be produced.

A Study on Impact and Countermeasures of Marine Fuels in the FuelEU Maritime Regulation (FuelEU Maritime 규제 적용에 따른 해양 연료의 영향분석 및 대응방안 연구)

  • Jin-Hyung Kim;Jae-Hyuk Choi
    • Journal of the Society of Naval Architects of Korea
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    • v.61 no.2
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    • pp.88-97
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    • 2024
  • This study performed the analysis on an economic feasibility of each marine fuel, potential fuel pathways and the relevance of compliance measures to ensure compliance with the FuelEU Maritime regulation. Additionally, it identified certain regulatory gaps to encourage the use of alternative marine fuels. Regarding GHG emissions calculations, the existing GHG regulations for ships applies the Tank-to-Wake (TtW) method, whereas FuelEU Maritime applies the Well-to-Wake (WtW) method. The main results present that important information to establish response strategy for FuelEU Maritime including the costs and benefits of each marine fuel, the minimum blending ratio of alternative fules, and compliance impacts of measures. For the regulatory costs and benefits of marine fuels following the implementation of the FuelEU Maritime from 2025, our findings indicate that while most fossil fuels incur regulatory costs from 2025, most of biofuels and RFNBO fuels do not incur costs until 2050. This will play a role to narrow the price gap between fossil fuels and alternative fuels.

A rapid and easy fabrication of plant-tissue biosensor using rubber binder and its practicability test (고무 결합재를 이용한 식물조직 바이오센서의 간편한 제작과 응용성)

  • Lee, Beom-Gyu;Rhyu, Keun-Bae;Yoon, Kil-Joong
    • Analytical Science and Technology
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    • v.22 no.5
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    • pp.355-359
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    • 2009
  • An enzyme electrode bound by rubber solution was newly constructed and the test of its practicability were carried out. The binder of carbon powder was styrene-butadiene rubber dissolved in toluene and enzyme source was ground tissue of cabbage root. Volatilization of the solvent made the electrode material possess a mechanical robustness and a fast signal appearance. The electrode showed electrochemically irreversible characteristics and a powerful catalytic power (detection limit=$5.0{\times}10^{-5}M$, S/N=2). The double reciprocal plot of signal current and substrate concentration was ideally linear and the symmetry factor and exchange current density of the electrode used in this work were 0.35 and $4.93{\times}10^{-5}Acm^{-2}$ respectively.

Robust Fuzzy Fingerprint Vault System against Correlation Attack (상관관계 공격에 강인한 지문퍼지볼트 시스템)

  • Moon, Dae-Sung;Chae, Seung-Hoon;Chung, Yong-Wha;Kim, Sung-Young;Kim, Jeong-Nyeo
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.21 no.2
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    • pp.13-25
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    • 2011
  • Biometric-based authentication can provide strong security guarantee about the identity of users. However, security of biometric data is particularly important as the compromise of the data will be permanent. The fuzzy fingerprint vault system is one of the most popular solutions for protecting the fingerprint template stored in the database. Recently, however, this system is very susceptible to a correlation attack that finds the real minutiae using multiple fingerprint vaults enrolled for different applications. To solve this problem, we propose a robust fuzzy fingerprint vault system against the correlation attack. In this paper, we add chaff minutiae based on the relative information of minutiae such as direction, coordinate instead of adding randomly. Also, our proposed approach allow to add multiple chaff minutiae within tolerance box for enhanced security level. Experimental results show that the proposed approach can protect the correlation attack and achieve enhanced verification accuracy.

Effect of Biozyme on Alcohol Metabolism

  • Park, Seung-Hee;Nam, Suk-Woo;Sungpil Yoon;Minsik Son;Nam, Tae-Kyun;Seo, Dong-Wan;Sungyoul Hong;Lee, Hyang-Woo
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1995.04a
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    • pp.91-91
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    • 1995
  • 에탄올에 의한 급성독성은 에탄올, 아세트알데히드 및 에탄을 대사산물의 변형생성물질 등에 기인하므로 알콜 섭취 후 혈중 에탄을 농도 및 아세트알데히드의 농도를 낮추는 것은 음주에 의한 급성 중독상태에 머무는 시간을 단축시키는데 중요하다. 본 실험에서는 Bacillus subtilis natto sp.를 식물 추출액을 배지로 하여 배양한 후 단백 분해효소로 고분자물질을 절단하여 얻은 발효액인 바이오짐(상품명: Biozyme)을 주성분으로 한 '비지니스(조선무약합자회사)' 의 인체 혈중 알콜대사 촉진작용을 검색하였으며, 비지니스 및 바이오짐이 랫드의 에탄을 대사에 미치는 효과를 검토하여 다음과 같은 결과를 얻었다. 인체 혈중 알콜대사 촉진작용을 검색하기 위해 알콜 섭취 전과 후의 혈중 에탄올 농도를 비교하였는데, 대조군에 비해 비지니스 투여군이 30분 후부터 2시간 후까지 혈청 알콜농도가 낮게 나타났다. 대조군의 혈청 알콜농도를 100으로 하였을 때 알콜 투여 30분, 60분, 90분, 120분 경과 후 시험군은 각각 대조군의 84.3%, 89,0%, 85.9%, 75.8%를 나타내어 평균 16% 정도 낮았다. 시험군의 AUC는 대조군의 AUC의 89%로 비지니스 투여군에서 혈액내 알콜의 제거가 빠르게 진전된다는 것을 보여주었다. 또한, 랫드의 에탄을 대사에 미치는 효과를 알아보고자 바이오짐 및 비지니스 투여 후 채혈하여 혈중 에탄을 및 아세트알데히드 농도를 측정하였다. 비즈니스 투여시 혈중 알콜 농도는 알콜 투여 60분 경과후 가장 큰 감소 효과(대조군:83.70$\pm$11.80mg/이, 시험군:45.12$\pm$6.63mg/d1, 47% 감소)를 나타내었으며, 시험군의 AUC는 대조군에 비해 30% 감소하였다. 혈중 아세트알데히드 농도는 투여 60분 후 비지니스 투여군(4.56$\pm$0.51nmol/$m\ell$)이 대조군(6.45$\pm$0.64nmo1/$m\ell$)에 비해 유의성 있는 감소(29%)를 나타내었으며, 시험군의 AUC는 대조군에 비해 35% 감소하였다. 바이오짐 투여시 혈중 에탄을 농도가 알콜 투여 2시간 경과 후 가장 큰 감소 효과(대조군:49.10$\pm$5.20mg/dl, 시험군:25.90$\pm$7.16mg/d1, 47% 감소)를 나타내었으며, 시험군의 AUC는 대조군에 비해 39% 감소하였고, 혈중 아세트알데히드의 농도는 투여 60분후 시험군(3.96$\pm$0.07nmo1/$m\ell$)이 대조군(6.45$\pm$0,64nmo1/$m\ell$)에 비해 유의성 있는 감소(39%)를 나타내었으며, 시험군의 AUC는 대조군에 비해 48% 감소하였다 한편, 시험관내 에탄올 대사 효소에 대한 바이오짐의 효과를 검색해본 결과 바이오짐(2.0 $\mu\textrm{g}$/assay)에 의해 Aldehyde dehydrogenase(1.5unit/assay)의 활성이 14% 증가되었다. 본 연구의 결과로 볼 때, 비지니스 및 바이오짐은 음주 후 상승된 혈중 에탄을 농도 및 아세트알데히드의 농도를 현저히 감소시키는 효과가 있었다.

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Applicability of Fomes fomentariusfor the formation of a mycelial mat (균사체 매트 제작을 위한 말굽버섯의 응용 가능성)

  • Kim, Hyun-Suk;Oh, Deuk-Sil;Jung, Young-Hyun;Shin, Hyun-Jae
    • Journal of Mushroom
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    • v.20 no.3
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    • pp.163-167
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    • 2022
  • Bio-based alternative leathers may be produced from biomass fiber, protein polymers, bacterial cellulose, and mushroom mycelia. Of these components, mushroom mycelia are of greatest interest. In this study, the potential of Fomes fomentariusas a mushroom mycelial mat was confirmed, and the optimal strain for the development of the mycelial mat was determined. Moreover, the quality of the mycelial mat was improved by identifying an efficient culture method to increase productivity. Mutant strains whose independence was verified were obtained by treatment with gamma irradiation under various conditions. Biofilm formation by the resulting strains was examined in sawdust and liquid media and the characteristics of the biofilms were analyzed. The biofilm of the mutant strains showed results that were similar to or better than the biofilms of longevity and cypress mushrooms. These findings are expected to be utilized in future research aimed at discovering new biomaterials using mushroom mycelia.

New IT R&D 발전방안

  • Choe, Mun-Gi
    • Information and Communications Magazine
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    • v.26 no.1
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    • pp.25-30
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    • 2009
  • IT산업은 '97년 외환위기를 기점으로 고성장을 거듭하였고, 세계 10위권 규모의 경제 강국으로 성장하는데 있어 국내 산업의 대표적인 성장동력으로서 자리 매김하였다. 하지만, 최근 성장률이 예전만 못하다는 우려의 목소리와 함께 IT가 한 단계 더 업그레이드하기 위해서는 자신의 허물을 과감히 벗는 용기가 필요하다는 것이 일반적인 시각이다. 이러한 흐름속에서 기존 IT전략과 차별화된 New IT 발전방안을 수립하게 되었다. 지금까지의 IT전략이 IT 고도화 추진을 위한 IT 중심 발전 전략이었다면, New IT전략은 IT기반 융합산업, IT융합 신산업, Next IT산업 등3대 성장축간 시너지 창출이 가능한 IT로의 수렴과 확산이 핵심이라고 할 수 있다. IT기반 융합산업의 최종 목표는 전통산업과 IT가 만나 자동차, 조선, 의료, 국방, 건설, 섬유, 기계항공 등 7개 주력기간산업의 고부가가치화 및 초일류화를 우선 실현하는 것이다. IT융합 신산업의 최종 목표는 나노(NT), 바이오(BT), 인지기술(CT) 등 비(非)IT와 교감을 통하여 IT가 에너지, 환경, 건강 등 사회적 문제를 해결하고, 녹색성장 추진의 핵심인 5대 신산업을 창출하는데 있다. 5대 신산업으로는 Green IT산업, Welfare-Infra산업, 감성조명산업, 인지단말산업, THz응용산업 등을 꼽을 수 있다. Next IT산업은 기존 14대 IT 분야를 'ETRI 비전 2020' 등 미래 청사진을 바탕으로 장기적 관점에서 재설계한 것이며, 최종 목표는 TDX, 4M D램, CDMA, 와이브로, DMB, NoLA 등 IT 강국 계보를 이어갈 4G, 미래인터넷, Smart Radio, 실감미디어, 웹3.0, 투명전자소자 등 미래 유망 핵심원천기술을 확보하고, IT 경쟁력을 강화하는 것이다.