• Journal of Nutrition and Health
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• v.42 no.5
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• pp.415-422
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• 2009

The present study was conducted to investigate the effect of dietary supplementation of grape pomace on lipid peroxidation and related enzyme activities of rats fed high fat diet. Male Sprague-Dawley rats weighing about 90 g were assigned to 4 experimental groups of 8 rats on the basis of their body weight. The high fat diet contained additional 15% lard to AIN 93-based diet. Rats were fed experimental diets containing 5% grape pomace for 4 weeks. Dietary supplementation of grape pomace reduced serum concentration of lipid peroxide in rats fed high fat diet. Hepatic concentration of lipid peroxide tended to be lower by feeding grape pomace. Hepatic total glutathione content and GSH/GSSG ratio were increased by grape pomace feeding in normal or high fat diet groups. Hepatic superoxide dismutase activity of grape pomace group with high fat diet was induced significantly compared with high fat diet group without grape pomace. Hepatic catalase activity of high fat fed rats was induced by feeding grape pomace. Grape pomace diet increased glutathione-S-transferase and glutathione peroxidase activities in rat liver fed high fat. Hepatic glucose-6-phosphatase activity was not affected by dietary supplementation of grape pomace in rats fed high fat. These results suggest that dietary supplementation of grape pomace may alleviate lipid peroxidation through antioxidant effect in rats fed high fat.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.20 no.2
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• pp.111-118
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• 2010

연구목적: 본 연구는 일반인의 비직업적 노출에 대한 혈중 16종의 다환방향족탄화수소(PAHs) 의 농도르 분석하여 PAHs의 백그라운드 노출 농도를 평가하는 것이다. 내용 및 방법: 농촌지역에 거주(비직업적 노출로서 16종 다환방향족탄화수소가 특정한 환경오염을 받지 않은 지역에 거주)하는 156명의 연구 참여자의 혈중 16가지 다환방향족탄화수소 농도의 기하평균치를 간접흡연군, 구운 음식물섭취군과 각대조군을 비교 하였다. 혈중 16종의 다환방향족탄화수소의 농도는 질량분석기를 장착한 가스크로마토그라피법과 헤드스페이스 마이크로고체상 추출법에 의하여 분석하였다. 결과: 연구참여자 중, 간접흡연자들에서 4종의 다환방향족탄화수소 아세나프틸렌(p<0.01), 아세나프텐(p<0.1), 플로렌(p<0.01), 피렌(p=0.05)가 대조군 보다 유의하게 높았다. 또한 구운육류와 생선 섭취군에서는 벤조(a)피렌(p<0.1)이 대조군 보다 유의하게 높았다. 결론: 간접흡연과 구운음식물 섭취는 비직업적 노출에서 다환방향족탄화수소 노출원의 가능성이 높다고 추정된다. 혈중 다환방향족탄화수소는 한국일반인의 비직업적 노출 농도로 사용 가능하다고 생각된다.

• The Journal of the Korea Contents Association
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• v.14 no.11
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• pp.378-388
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• 2014

This research is to figure out the influence of hand holding and Nea-Guan acupressure to anxiety and pain that local anesthesia patients feel in out patient operation room. Non equivalent control group pretest-posttest time series design was adopted and the data had been collected from Jul. to Oct. 2013. Total 78 local anesthesia patients of out patient operation room in the H Hospital were allotted by control group, experimental group 1( hand holding) and experimental group 2(Nea-Guan acupressure) which consisted of 26 patients each. Hand holding and Nea-Guan acupressure in this research was validated to relieve the anxiety and the pain of the local anesthesia patients in operation and can be adopted as an efficacious nursing interventions.

• Journal of Digital Convergence
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• v.12 no.7
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• pp.297-304
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• 2014

The present study was designed to investigate the effect of home based exercise program on balance recovery of stroke patients. In total, 20 participants were assigned to a control group(n=10) or exercise group(n=10) between September 2013 and December 2013. In addition to existing physiotherapy, the exercise group received home based exercise program consisting of weight transfer, training endurance, mobility, sensory retraining, lower limb exercise for 30 minutes, 2 times a week, for 8 weeks, every time for 30 minutes. Balance ability was assessed by measuring foot pressure(FP), limit of stability(LOS) and velocity sway(VS) by using Biorescue and by using the functional reaching test(FRT). To compare the improvement level of each group's balance ability, examination of independent sample T was done. Significant differences between control group and exercise group in LOS, VS of affect side and FRT were observed. This study showed that home based exercise program application was effective strategy on balance recovery in a post stroke population.

• Journal of Chest Surgery
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• v.29 no.10
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• pp.1076-1080
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• 1996

The results about the myocardial protection of recta of the nitric oxide precursor L-arginine upon reperrusion injury after ischemia are diverse. These diversities may be model dependent. Experiments were designed and performed to investigate myocardial protection effects according to the concentration of L-arginine. The Isolated rat hearts were subjected in a 30 minutes oi normothermic ischemia and reperfused for 30 minutes with reperfusate containing 0, 1, 2, 3, 4 moil L-arginine. After 30 minutes of reperfusion, group with 1 and 2 mM/L L-arginine showed a trend of better recovery in left ventricular systolic function(left ventricular developed pressure, positive maximum dpfdt), diastolic function(negative maximum dpfdt) and coronary flow compared to control group(reperfusate no L-arginine). Recovery was impaired with a higher concentration, and at 4 moil L-arginine r covery was worse than control(p (0, 05). These results suggest that optimal concentration of L-arginine Is Important or the recovery of myocardial and endothelial function after ischemia and reperfusion.

• Journal of Food Hygiene and Safety
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• v.19 no.4
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• pp.193-197
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• 2004

To evaluate the bacterial reverse mutation of wild ginseng culture extract, the in vitro Ames test using Salmonella typhimurium (TA100, TA1,535, TA98, TA1,537) and Escherichia coli (WP2 uvrA) were performed with wild ginseng extract at the concentrations 0, 1.6, 8, 40, 200, 1,000, 2,500 and $5,000{\mu}g/ml/plate$. Wild ginseng culture extract was negative in Ames test with both Salmonella typhimurium or Escherichia coli with and without rat liver microsomal enzyme (S-9 fraction). According to these results, we concluded that wild ginseng culture extract did not cause bacterial reverse mutation.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.10
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• pp.1213-1219
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• 2012

A remote $CO_2$ laser system can rapidly change both the distance and the direction of the laser beam by moving a lens and rotating mirrors. It is then easy to weld complex patterns of weld lines. A conventional spot weld joint specimen and a remote $CO_2$ laser weld joint specimen with complex weld line patterns were prepared and tested both statically and dynamically. The relationships between the fatigue strength, i. e. the maximum cyclic force, and the fatigue life were obtained. The fatigue strength of the tested welded joints at two million cycles was found to be approximately 10% of the static strength. Furthermore, it was observed that the fatigue fracture mode changed with the level of the applied cyclic force. The fatigue crack origins were confirmed as the highest stress points found in the structural analysis. The maximum cyclic stress for different weld patterns converges as the fatigue life approaches two million cycles.

• Journal of Digital Contents Society
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• v.18 no.4
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• pp.699-706
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• 2017

This study aims to investigate the effects of a massage device with vibration and pressure functions and a manual massage on the degree and duration of pain among patients after intramuscular injection. This study used a quasi-experimental design with nonequivalent control group. The experimental group had lower pain scores (t= 7.40, p =.001) and shorter durations of pain (t= 5.25, p=.001) than the control group. The results showed that after intramuscular injection, a massage device with vibration and pressure functions effective to reduce the degree and duration of pain than a manual massage. Therefore, the application of a massage device with vibration and pressure functions after intramuscular injection will contribute to the promotion of patient safety and the reduction of nurse workload.

• The Journal of the Korea Contents Association
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• v.19 no.2
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• pp.210-222
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• 2019

The purpose of this study was to identify the effectiveness of Mindfulness-Based Cognitive Therapy(MBCT) program on stress, self-esteem and depression of nursing college students. Thirty-eight students were enrolled by convenience sampling in this study and allocated to control (n=20) and experimental group (n=18). In the intervention group, Mindfulness-Based Cognitive Therapy program was applied over 8 sessions, while the control group received material of MBCT program. The data were analyzed using the Independent t- test, Chi-square test and Fisher's exact test. There was significant difference in stress and depression between the groups, but the self-esteem did not show any significant effect. The results showed that MBCT program is effective to regulate stress and depression of nursing college students and a further study is needed to explore the effect of MBCT program on stress and depression of nursing college students.

• Journal of the Korea Convergence Society
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• v.9 no.8
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• pp.101-108
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• 2018

This study aimed to investigate the blood glucose regulatory effect of barley noodles contained mulberry leaves water extract (MLWE) in diabetic mice in order to provide fundamental data as a functional food. ICR mice were divided into six groups as follows: normal control, positive control, barley control, mulberry control, barley+MLWE 2.5% and barley+MLWE 5% groups. High fat/high carbohydrate diet was fed for 4 weeks and diabetes mellitus was induced by i.p. injection of streptozotocin and nicotinamide. After diabetes induction, experimental diet was supplemented for 2 weeks and simultaneous measurement of body weight, blood glucose (including glucose tolerance test), liver function and blood lipid profile was conducted. As a result, there was less decrease in body weight compared to the positive control group in the groups that supplemented barley and MLWE together than the group ingesting barley and MLWE alone. In addition, regulatory effects on blood glucose, liver function and blood lipid concentration were also stronger in barley and MLWE concurrently supplemented groups. Consequently, combination of barley and MLWE was effective in the regulation of body weight, blood glucose, liver function, and blood lipid in diabetic mice. Therefore, this recipe could be a promising strategy for beneficial effects in the patients of diabetes mellitus.