• Title/Summary/Keyword: 제3의 공간성

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A Novel Glycine-Rich Region in Sox4 is a Target for the Proteolytic Cleavage in E. coli (전사활성 인자인 Sox4의 단백질 분해효소에 의한 표적 부위에 관한 연구)

  • 허은혜;최주연;장경희;김인경;임향숙
    • Korean Journal of Microbiology
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    • v.38 no.3
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    • pp.153-161
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    • 2002
  • Sox4, a transcription factor, consists of three functional domains: an HMG-box domain as a DNA binding domain, serine rich region as a transactivation domain and glycine rich region (GRR), an unknown functional domain. Although Sox4 is known to be functionally involved in heart, B-cell and reproductive system development, its physiological function remains to be elucidated. We used pGEX expression system to develop a simple and rapid method for purifying Sox4 protein in suitable forms for biochemical studies of their functions. Unexpectedly, we observed that full-length Sox4 appears to be protease-sensitive during expression and purification in E. coli. To map the protease-sensitive site in Sox4, we generated various constructs with each of functional domains of Sox4 and purified as the GST-Sox4 fusion proteins using glutathione beads. We found that the specific cleavage site for the proteolytic enzyme, which exists in E. coli, is localized within the novel GRR of Sox4. Our study suggest that the GRR of Sox4 may a target for the cellular protease action and this cleavage in the GRR may be involved in regulating physiological function of Sox4. Additionally, our study may provide a useful method for investigating the proteolytic cleavage of the target molecule in E. coli.

The Reactivity for the SO2 Reduction with CO and H2 over Sn-Zr Based Catalysts (Sn-Zr계 촉매 상에서 CO와 H2를 이용한 SO2 환원 반응특성)

  • Han, Gi Bo;Park, No-Kuk;Ryu, Si Ok;Lee, Tae Jin
    • Korean Chemical Engineering Research
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    • v.44 no.4
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    • pp.356-362
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    • 2006
  • The $SO_2$ reduction using CO and $H_2$ over Sn-Zr based catalysts was performed in this study. Sn-Zr based catalysts with Sn/Zr molar ratio (0/1, 1/4, 1/1, 2/1, 3/1, 1/0) were prepared by the precipitation and co-precipitation method. The effect of the temperature on the reaction characteristics of the $SO_2$ reduction with a reducing agent such as $H_2$ and CO was investigated under the conditions of space velocity of $10,000ml/g_{-cat.}h$, $([CO(or\;H_2)]/[SO_2])$ of 2.0. As a result, the activity of Sn-Zr based catalysts were higher than $SnO_2$ and $ZrO_2$. The reactivity for the $SO_2$ reduction with CO was higher than that with $H_2$, and sulfur yield in the $SO_2$ reduction by $H_2$ was higher than that by CO. The reactivity for the $SO_2$ reduction with $H_2$ was increased with the reaction temperature regardless of Sn-Zr based catalyst with a Sn/Zr molar ratio. $SnO_2-ZrO_2$ (Sn/Zr=1/4) had highest activity at $550^{\circ}C$, in the $SO_2$ reduction with $H_2$ and $SO_2$ conversion of 94.4% and sulfur yield of 66.4% were obtained at $550^{\circ}C$. On the other hand, in the $SO_2$ reduction by CO, the reactivity was decreased with the increase over $325^{\circ}C$. At the optimal temperature of $325^{\circ}C$, $SO_2$ conversion and sulfur yield were about 100% and 99.5%, respectively, in the $SO_2$ reduction over $SnO_2-ZrO_2$ (Sn/Zr=3/1). Also, the $SO_2$ reduction using syngas with $CO/H_2$ ratio over $SnO_2-ZrO_2$ (Sn/Zr=2/1) was performed in order to investigate the application possibility of the simulated coal gas as the reductant in DSRP. As a result, the reactivity of the $SO_2$ reduction using syngas with $CO/H_2$ ratio was increased with increasing the CO content of syngas. Therefore, it could be known that DSRP using the simulated coal gas over Sn-Zr based catalyst is possible to be realized in IGCC system

Quality Control of Pluvio Snowfall Data Using Parsivel (광학우적계를 이용한 무게식 우량계 적설 자료 품질 관리)

  • Ro, Yonghun;Chung, Gunhui
    • Proceedings of the Korea Water Resources Association Conference
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    • 2018.05a
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    • pp.80-80
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    • 2018
  • 겨울철 대설 현상에 따른 도로 결빙과 항공기 운항 지연, 비닐하우스 및 가건물 붕괴와 같은 피해가 증가함에 따라 대처방안을 마련하는 일이 중요시 되고 있다. 이를 위해 정확한 적설 정보가 근본적으로 필요하지만, 문제는 적설량을 정량적으로 관측하는 일이 간단하지 않다는 점이다. 최근에는 무게식 우량계를 이용한 적설 관측이 수행되고 있지만, 강설량이 많을 경우 우량계가 눈에 덮이는 캐핑(capping) 현상으로 인해 제대로 관측하기 어려운 문제가 있다. 본 연구에서는 무게식 우량계의 이러한 한계를 보완하고 자료의 활용성을 높이기 위해 광학우적계(Parsivel)로 관측된 강설입자정보를 이용하여 적설량을 보정하는 방법을 제안하였다. 무게식 우량계 자료는 대관령 구름물리선도센터에 설치되어 있는 플루비오(Pluvio)의 적설 관측 자료를 이용하였다. 먼저, 관측된 플루비오 자료에서 단위 시간동안의 신적설을 산정한 후 과도한 관측값과 같은 노이즈를 제거하였다. 또한 플루비오와 동일 기간에 관측된 광학우적계 자료에 대해 강설 입자가 $10/m^3$ 초과로 나타나는 사상을 강수 기간으로 결정하고 두 자료가 모두 '0'인 경우 무강수로 나타냈다. 그 결과 강수 입자가 관측된 적설 기간에 플루비오가 우수하게 강설 사상을 관측하고 있음을 확인하였고, 부적합한 자료를 보정할 수 있었다. 이러한 방법으로 적설 자료를 개선할 경우 향후 레이더를 이용한 공간적 강설 추정의 정확도를 크게 개선할 수 있을 것으로 판단된다.

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A Study on the Evaluation of 3D Dose Distribution using Normoxic Polymer Gel (정상산소 중합체 겔 선량계를 이용한 3차원 방사선량 평가에 관한 연구)

  • Chung, Se-Young;Kim, Young-Bum;Kwon, Young-Ho;Lee, Suk
    • The Journal of Korean Society for Radiation Therapy
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    • v.19 no.1
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    • pp.7-17
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    • 2007
  • Purpose: As increasing complexity of modern radiotherapy technique, more developing dosimetry is required. Polymer gel dosimeters offer a wide range of potential applications with high resolution and assured quality in the thee-dimensional verification of complex dose distribution such as intensity-modulated radiotherapy (IMRT). The purpose of this study is to find the most sensitive and suitable gel as a dosimeter by varying its composition ratio and its condition such as temperature during manufacturing. Materials and Methods: Each polymer gel with various ratio of composition was irradiated with the same amount of photon beam accordingly. Various polymer gels were analyzed and compared using a dedicated software written in visual C++ which converts TE images to R2 map images. Their sensitivities to the photon beam depending on their composition ratio were investigated. Results: There is no dependence on beam energy nor dose rate, and calibration curve is linear. Conclusion: The polymer gel dosimeter developed by using anti-oxidant in this study proved to be suitable for dosimetry.

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Analysis of the Current Status and Proposals for Policy Tasks of Public Libraries in Daegu City (대구시 공공도서관 현황 분석 및 정책과제 제안)

  • Hee-Yoon Yoon;Seon-Kyung Oh
    • Journal of Korean Library and Information Science Society
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    • v.54 no.2
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    • pp.43-65
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    • 2023
  • The purpose of all public libraries is to provide knowledge and information services for the intellectual and reading activities of local residents, program services that provide opportunities for cultural enjoyment and lifelong learning, and third-party spaces and facilities that contribute to the development of the community. To this end, social needs must be reflected in a timely manner with the establishment of a sound infrastructure as a prerequisite. This study analyzed the current status centered on key indicators of the public libraries in Daegu City and presented policy issues that need to be improved through a survey. The key indicators in Daegu City, compared to the national average, were not only significantly weak for the 3rd largest city but also showed considerable variation among local governments. While Daegu citizens valued public libraries in their daily lives, the dissatisfaction rate was high in the order of transportation inconvenience, lack of necessary materials and desired programs, and various regulations. Therefore, Daegu City should focus on increasing the acquisition budget, strengthening the development of new book collections, expanding the number of librarians, expanding the construction of public libraries to address service disparities among local governments, improving accessibility, and addressing factors that hinder usage. In addition, with the establishment and operation of the Daegu Library in 2024, efforts should be made to establish an operational system for public libraries, expand the scope through collaborative partnerships with other knowledge and cultural institutions, and enhance knowledge and cultural services for the Daegu citizen.

A Study on the Landscape Characteristics and Implications of the Royal Garden through 「The 36 Scenery of Seongdeok Summer Mountain Resort」 by Kangxi Emperor (강희제(康熙帝)의 「승덕 피서산장(避暑山莊) 36경」에 담긴 황가원림의 경관 특성과 함의)

  • RHO Jaehyun;MENG Zijun
    • Korean Journal of Heritage: History & Science
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    • v.55 no.4
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    • pp.212-240
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    • 2022
  • This study is a multi-layered exploration of 「The Thirty-Six Scenery of Seongdeok Summer Mountain Resort(承德避暑山莊三十六景)」 (The 36th view of Kangxi) recited by Emperor Kangxi of China through literature study, ancient calligraphy diagrams, and field studies. The conclusion of tracing the landscape characteristics and implications contained in 「The 36th view of Kangxi」 through the analysis of the headword(標題語) and the interpretation of the Jeyeong poem(題詠詩) is as follows. 「The 36th view of Kangxi」 is an extension of the outer edge of the Eight Sceneries, and when compared to the existing Eight Sceneries peom and Eight Sceneries painting, it is found that the landscape is centered on the 'viewpoint' rather than the landscape object. In particular, it aimed to create a structured landscape centered on nine types of buildings represented by 'Jeon(殿)' and 'Jeong(亭)' was given. In particular, Yeouiju, located in Lake district, is a scenic country endowed with the character of a gardens in Garden, which is composed by collecting famous representative Chinese landscapes and landscapes of Sansu-si and Sanshu Painting. As a result of headword analysis to understand the characteristics of landscape components, 14 landscapes (38.9%) related to water elements and 13 landscapes(36.1%) related to mountain elements, the elements related to architecture and civil engineering were classified in the order of 3 cases(8.3%), and the elements related to the skylight were classified in the order of 2 cases(5.6%). However, in Jeyeong-si, the mention of landscape vocabulary for climate elements was overwhelming. In other words, in the poems of 「The 36th Scenery of Kangxi」, scenery vocabulary symbolizing 'coolness' such as 雲(cloud), 水(water), 泉(spring), 清(clear), 波(wave), 流(wave), 風(wind) and 無暑(without heat), etc. It is not a coincidence that it appears, and it is strongly attached to the sense of place of Summer Mountain Resort in Rehe(熱河). Among the 23 landscapes whose seasonal background was confirmed, the fact that the lower landscape is portrayed as the majority and the climate elements of the resort area are portrayed in three-dimensional and multi-dimensional ways are closely related to the period of enjoying the gardens of Kangxi, the main subject of the landscape. In addition, many animal and plant landscapes appearing in Jeyeong-si appear to be in the same context as the spatial attributes of not only recreation, but also contemplation and hunting. On the other hand, in Jeyeongsi, there are 33 wonders(91.7%) citing famous people and famous books through ancient poems, old stories, and ancient stories tends to be prominent. It is inferred that this was based on Kangxi's understanding and pride in traditional Chinese culture. In 「The 36th view of Kangxi」, not only a book-writing description of the feelings of being entrusted to the family sutras, but also the spirit of patriotism, love, self-discipline and respect for mother and filial piety are strongly implied. Ultimately, 「The 36th view of Kangxi」 shows the real scene of the resort, as well as the spiritual dimension, in a multi-faceted and three-dimensional way, and the spirit of an emperor based on the dignity of the royal family and the sentiments of a writer it deserves to be called a collection of imperial records that were intended to reveal.

Analysis of Security Technology for Internet of things (사물인터넷 보안 기술 분석)

  • Lee, Ho-Tae
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.17 no.4
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    • pp.43-48
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    • 2017
  • Today our society is approaching new intelligence information society, which has been caused by the Fourth Industrial Revolution along with the development of information and communication technology(ICT). And this has just opened a new era of Internet of Things(IoT) that connects between human and objects and between objects through network, allowing transmission and reception of information beyond the limits of space. However, many crises occurred in the existing communication environment may threaten the security of Internet of Things, by violating the three components of information security. In this paper, this study aims to analyze security technology to achieve advanced security by dividing IoT security technology for coping with security vulnerability found in different components into three groups.

An Improvement of Efficiently Establishing Topographic Data for Small River using UAV (UAV를 이용한 소하천 지형자료 구축에 관한 효율성 제고)

  • Yeo, Han Jo;Choi, Seung Pil;Yeu, Yeon
    • Journal of Korean Society for Geospatial Information Science
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    • v.24 no.1
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    • pp.3-8
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    • 2016
  • Due to the recent technical development and the enhancement of image resolution, Unmanned Airborne Vehicles(UAVs) have been used for various fields. A low altitude UAV system takes advantage of taking riverbed imagery at small rivers as well as land surface imagery on the ground. The bathymetric data are generated from the low altitude UAV system. The accuracy of the data is analyzed along water depths, comparing GPS observations and a DSM generated from UAV images. It is found that the depth accuracy of the geospatial data below 50 cm depth of water satisfies the regulation(${\pm}10cm$ spatial accuracy) of bathymetric surveying. Therefore this research shows that the geospatial data generated from UAV images at shallow regions of rivers can be used for bathymetric surveying.

A Study on the Changes of the Government Pavilion, Miryang Yeongnamnu in terms of Function and Spatiality (객사(客舍) 누각(樓閣)의 기능 및 공간성 변화 - 밀양(密陽) 영남루(嶺南樓)를 대상으로 -)

  • Ryoo, Seong-Lyong
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.8
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    • pp.69-76
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    • 2018
  • This study is basically about the changing appearance of the big pavilion, Yeongnamnu in Miryang city belonging to the government guesthouse of Joseon dynasty. And the purpose of this study confirms that even if the appearance of the building has not changed, the function of the building changes because the reason why people think about the building is also different. First, looked at the appearance of architecture and the function of architecture that changes with the times. In the course of the research, the changes of pavilion were traced by dividing it into five from Kory? dynasty which was first established to the present. Then, tried to find out the change patterns by analyzing important events related to buildings or places in each period. As a result, the following facts were confirmed. 1. Because of the Buddhist repression policy in Joseon Dynasty, the Yeongnamnu changed from the temple pavilion to the government pavilion. 2. Throughout the Joseon Dynasty, Yeongnamnu was the representative scenic of Miryang City. 3. In the late Joseon Dynasty, Yeongnamnu was famous as a place where a woman named Arang devoted her life in order to preserve his fidelity. 4. Since 1910, Yeongnamnu has become an important cultural asset, and space has been widely used as a venue for various public events. 5. From 1945 to 1999, Yeongnamnu was used mainly for the events of Arang Remembrance and Miryang Culture Festival. And the inner space of Yeongnamnu was rarely used because people thought preservation is important.

Discourse of Library Trilemma in the Context of Global Megatrend (글로벌 메가트렌드와 도서관 트릴레마 담론)

  • Yoon, Hee-Yoon
    • Journal of Korean Library and Information Science Society
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    • v.52 no.1
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    • pp.1-26
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    • 2021
  • In most countries, public libraries have played a role as a hub of knowledge and information, complex culture of local communities, and a third place for meeting and communication. And recent public libraries are focusing on enhancing their core competencies and expanding services using digital technologies to meet the era of digital transformation and the 4th industrial revolution. However, after the COVID-19 pandemic occurred, all public libraries are repeatedly closed, reopened, and partially closed, and all resources are devoted to providing non-contact, digital and online alternative services, and are expected to continue in the future. As a result, future public libraries are bound to face a trilemma in which digital expandability, complex cultural space, and importance as a place of knowledge and information service are conflicting. This study discoursed on the public library trilemma in the post-COVID-19 era and suggested ways to overcome it. The orientation of the future public library is the fusion and harmony of multiplicity and multipurpose, place and space, knowledge & information and complex culture, face-to-face service and remote service. The main body of a public library is not the finger (digital and non-contact), but the moon (knowledge information center).