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Development of an Automated Synthesizer for the Routine Production of Ga-68 Radiopharmaceuticals (임상용 Ga-68 표지 방사성의약품의 합성을 위한 자동합성장치 개발)

  • Jun Young PARK;Jeongmin SON;Won Jun KANG
    • Korean Journal of Clinical Laboratory Science
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    • v.55 no.4
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    • pp.253-260
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    • 2023
  • The germanium-68/gallium-68 (68Ge/68Ga) generator has high spatial utilization and requires little maintenance, making it economical and easy to produce. Thus, the frequency of use of 68Ga radiopharmaceuticals is rapidly increasing worldwide. Therefore, this study attempted to develop an automated synthesizer for the routine clinical application of 68Ga radiopharmaceuticals. The automated synthesizer was based on a fixed tubing system and the structure was designed after adjusting the position of the parts to reflect the synthesis method. Using various components that can be supplied in Korea, the automated synthesizer was manufactured at a much lower price cost than that of a commercialized automated synthesizer sold by companies. 68Ga-DOTA-[Tyr3]-octreotide (68Ga-DOTATOC) was synthesized to evaluate the performance of the automated synthesizer. 68Ga-DOTATOC could be synthesized with about 65% of non-decay corrected yield, and the synthesized 68Ga-DOTATOC met all quality control standards. We have synthesized 68Ga-DOTATOC more than 100 times, and only faced a few problems caused by mechanical errors. In this study, we successfully developed a simple automated synthesizer for 68Ga radiopharmaceuticals with high reproducibility. As various 68Ga radiopharmaceuticals have recently been developed, it is expected that the automated synthesizer developed in this study will be useful for routine clinical use.

Analysis of Consumer Consumption Status and Demand of Rice-wine (약주에 대한 소비자의 소비실태 및 요구도 분석)

  • Kim, Eun-Hae;Ahn, Byung-Hak;Lee, Min-A
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.3
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    • pp.478-486
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    • 2013
  • The purpose of this study was to analyze consumer consumption and product concept demands of Korean rice-wine. An online survey, conducted from April 28, 2010 to May 6 2010, targeted 200 consumers in Seoul and the Gyeonggi-do area. More than half of the respondents (51.3%) drank rice-wine because of the taste. The common reasons for dissatisfaction with rice-wine were hangovers (35.7%) and taste (16.9%). From analyzing rice-wine preferences, the most preferred ingredient was rice (57.8%), while the most preferred aroma and taste was derived from the fruit (48.7% and 58.4%, respectively). The most common methods consumers observed for promoting rice-wine consumption were the "development and management of rice-wine brands" (59.7%), and "continuous promotion" (44.8%). The most important attributes of a rice-wine product included its taste (4.60), followed by its quality (4.41) using 5-point Likert scale. An importance-performance analysis (IPA) was performed for the 17 attributes of rice-wine and identified targets for product management strategies, including the "usage of domestic ingredients", "ease of purchase", clarity of "product information", and "external image". Therefore, developing solid concepts in marketing strategy are required and may be achieved by understanding the consumer preferences and demands of rice-wine.

Residue levels of phthalic acid esters (PAEs) and diethylhexyl adipate(DEHA) in various industrial wastewaters (업종별 산업폐수 중 프탈산에스테르와 디에틸헥실아디페이트의 잔류수준)

  • Kim, Hyesung;Park, Sangah;Lee, Hyeri;Lee, Jinseon;Lee, Suyeong;Kim, Jaehoon;Im, Jongkwon;Choi, Jongwoo;Lee, Wonseok
    • Analytical Science and Technology
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    • v.29 no.2
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    • pp.57-64
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    • 2016
  • Many phthalic acid esters (PAEs), including DMP, DEP, DBP, BBP, and DEHP, as well as DEHA are widely used as plasticizers in plastics. An analytical method was developed and used to analyze these compounds at 41 industrial facilities. The coefficient of determination (R2) for each constructed curve was higher than 0.98. The method detection limit (MDL) values were 0.4–0.7 μg/L for PAEs and 0.6 μg/L for DEHA. In addition, the recovery rate was shown to be 77.0–92.3%, while the relative standard deviation was shown to be in the range of 5.8-10.5%. DMP (n = 3), DEP (n = 2), DBP (n = 2), BBP (n = 2), and DEHA (n = 3) were detected in the range of 2.2-11.1% in the influent. DEHP was a predominant compound and was detected at > MDL in both the influent (n = 16, 35.6%) and the effluent (n = 4, 10.0%) at a high removal efficiency (92–100%). The highest levels of residue in industrial wastewater influent were 137.4 μg/L of DEHP at plastic products manufacturing facility, 12.5 μg/L of DEHA at a chemical manufacturing facility, and 14.0 μg/L of DEP at an electronics facility. The highest concentration of effluent was 12.5 μg/L of DEHP at a chemical manufacturing facility, which indicated that the effluent was below the allowable concentration (800 μg/L). Therefore, the levels of PAEs and DEHA that are discharged into nearby streams could not influence the health of the ecosystem.

Effective Operation and Management Systems of Faculties in Mokpo National Maritime University for Differentiated Marine Education (해양계 특성화를 위한 효율적인 학부제 운영 체제 개선 -목포해양대학교를 중심으로-)

  • Kim Kwang Soo;Ahn Young-Seob
    • Proceedings of KOSOMES biannual meeting
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    • 2004.05b
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    • pp.127-150
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    • 2004
  • 목포해양대학교 현행 4개 학부의 교육과정은 1997년도에 전면 개편되어 학부 단위로 무난히 실시되고 있지만, 해사계열의 특수성과 해양공학계열의 학부별 전공 구성의 차이점 등으로 인하여 일률적 학부운영방침을 대학 전체에 동일하게 적용하는 것은 다소무리가 있었다. 해양계 특성화라는 대학의 목표를 향하여 각 학부의 교육목표와 전공특성을 살리면서 사회와 관련산업계의 시대적인 요구를 만족시키기 위하여 학부운영을 효율화$\cdot$극대화할 수 있는 체제 정립 방안을 연구하고 있다. 1차 년도의 연구결과에 의하면, 해상운송시스템학부는 효율적인 학부운영체제의 개선 및 운영시스템 개발을 위하여 학부 특성 및 전공 구성에 대한 분석을 통하여 문제점을 발견하고 해결방안을 모색함과 동시에 학생들의 전공 선택권을 최대한 보장할 수 있는 효율적인 학부 운영 체제를 구축하는 방안을 제시한다. 기관시스템공학부는 현행 의무복수전공제도의 문제점 분석과 해결 방안 강구를 위하여 전공들간의 인계성을 강화하며 활성화할 수 있는 방안을 모색하고 해양경찰학 전공의 운영 및 지도 방안을 연구한다. 또한 해기품질관리 관련 규정 등의 분석을 통해 교육 및 훈련에 대한 질적 향상을 꾀하고 해기품질 향상을 위한 교육평가시스템을 개발하고 구축하고자 한다. 해양전자$\cdot$통신공학부는 전공간의 연계성 구축과 효율적 운영방안을 모색하기 위하여 학부제 및 복수전공제와 관련하여 설문조사 문항을 개발$\cdot$분석하고, 해양전자공학 전공 교과목 정비 및 교재 개발을 시도하고 있다. 해양시스템공학부는 전공구성의 특성을 고려한 탐색과목의 설치 및 산업체 실습과 연계한 학점인정과목의 검토를 위하여 현행의 전공소개 프로그램을 분석하고, 졸업생의 취업을 분석하며 산업체의 요구사항을 조사하고 있다.산 알고리즘의 정당성을 보였다. 맞이하고 있음을 볼 수 있다. 국내광업이 21C 급변하는 산업환경에 적응하여 생존하기 위해서는 각종 첨단산업에서 요구하는 소량 다품종의 원료광물을 적기에 공급 할 수 있는 전문화된 기술력을 하루속히 확보해야 하며, 이를 위해 고품위의 원료광물 확보를 위한 탐사 및 개발을 적극 추진하고 가공기술의 선진화를 위해 선진국과의 기술제휴 등 자원산업 글로벌화 정책이 절실히 요구되고 있음을 알 수 있다. 또한 삶의 질을 향상시키려는 현대인의 가치관에 부합하기 위해서는 각종 소비제품의 원료를 제공하는 광업의 본래 목적 이외에도 자연환경 훼손을 최소화하며 개발 할 수밖에 없는 구조적인 어려움에 직면할 수밖에 없다. 이처럼 국내광업이 안고 있는 여러 가지 난제들을 극복하기 위해서는 업계와 정부가 합심하여 국내광업 육성의 중요성을 재인식하고 새로운 마음가짐으로 관련 정책을 수립 일관성 있게 추진해 나가야 할 것으로 보인다.의 연구 결과를 요약하면 다음과 같다. 첫째, 브랜드 이미지와 서비스 품질과의 관계에서 브랜드이미지는 서비스 품질의 선행변수가 될 수 있음을 증명하였으며 4개 요인의 이미지 중 사풍이미지를 제외한 영업 이미지, 제품 이미지, 마케팅 이미지가 서비스 품질에 영향을 미치고 있음을 알 수 있다. 둘째, 지각된 서비스 품질과 가격 수용성과의 관계에서, 서비스 품질은 최소 가격에 신뢰서비스 요인에서 정의 영향을 미치고 있으나 부가서비스, 환경서비스에서는 역의 영향을 미침을 알수 있고, 최대 가격에 있어서는 욕구서비스 요인은 정의 영향을 미치지만 부가서비스의 경우에는 역의 영향을 미치고 있음을 알 수 있다. 셋째, 서비스품질과 재 방문 의도와의 관계에 있어서 서비스품질은 재 방문 의도에 영향을 미침을 알 수 있다. 따라서 브랜드 이미지는 서비스품질의 선행변수가 될 수 있으며, 서비스품

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Analysis of the consumption pattern of delivery food according to food-related lifestyle (식생활라이프스타일에 따른 배달음식의 소비성향 분석)

  • Heo, So-Jeong;Bae, Hyun-Joo
    • Journal of Nutrition and Health
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    • v.53 no.5
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    • pp.547-561
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    • 2020
  • Purpose: This study was conducted to segment the delivery food market and to develop customized products and services. Methods: This study analyzed 636 responses collected from customers who ordered delivery food. Statistical analyses were conducted using the SPSS program (ver. 25.0) for frequency analysis, χ2-test, one-way analysis of variance, factor analysis, and cluster analysis. Results: Four factors were extracted by exploratory factor analysis (safety-orientation, convenience-orientation, taste-orientation, and economy-orientation) to explain the consumers' food-related lifestyles. The results of cluster analysis indicated that the 'low-interest group', 'convenience and economy-oriented group', and 'gourmet and economy-oriented group' should be regarded as the target segments. Characteristic analysis of each cluster showed that lowinterest group had higher rates of married (67.1%) and living with family (85.4%) than other clusters. The convenience and the economy-oriented group had higher rates of living alone (28.9%) than others. The gourmet and the economy-oriented group had a higher percentage of unmarried (62.0%) than the others. In addition, the average age of convenience and economy-oriented group (32.3 years) and gourmet and economy-oriented group (32.5 years) were significantly lower than the safety seeker (40.0 years) (p < 0.001). Difference analysis of the consumption practice according to the cluster, revealed significant differences in the order frequency (p < 0.001), main day to order (p < 0.05), source of information about delivery food (p < 0.001), order method (p < 0.001), and co-consumer (p < 0.01). In addition, the convenience and the economy-oriented group had significantly higher overall satisfaction than the others (p < 0.001). Conclusion: These findings suggest that customer segmentation based on a food-related lifestyle can be used to build a successful marketing strategy. Therefore, restaurant managers and delivery platform operators should consider developing products and services according to the segmentation to maximize customer satisfaction.

A Study of Power Perception between Supplier and Retail Buyer of Agricultural Products (농산물공급자와 대형소매업체 바이어간의 상호 파워 인식에 대한 연구)

  • 서성무;이은정
    • Proceedings of the Korean DIstribution Association Conference
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    • 2003.02a
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    • pp.123-166
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    • 2003
  • Marketing channel is recognized as one of the society systems which have the character of functional organization. These organizations are related to each other for specialized and cooperative work. Channel members in distribution channel are striving to accomplish exchange through reciprocal action. Thus channel members exercise their power to take better position in exchange. There will be struggling between members about satisfaction and conflict during this power exercise. Now a days, buyers use more harsh power as large retail firms are increasing. This phenomenon is occurring in the distribution channel. However, there will be different phenomenon in case of agricultural products. Not like industrial product suppliers, agricultural product suppliers have various supply channels and many agricultural products are seasonal. It has also unstable amount supplies. There should be differentiated marketing in agricultural products. Relatively weaker powered suppliers have to strengthen comparative factors and also have to be technically specialized through assessed experience in order to establish strong product sales chain. Making a brand of agricultural product would be also a good idea to increase the product comparability. Channel members need to be recognized their specialized functions in order to make balanced distribution channel. There have to be conversion of concept of relation between suppliers and buyers from subordinate relationship to cooperative relationship.

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A Study on the Manufacture of Hard-board Utilized Amino-resins as the Sizing Materials for the Strength Increase (아미노수지(樹脂)를 보강제(補强劑)로 이용(利用)한 경질섬유판(硬質纖維板) 제조(製造)에 관(關)한 연구(硏究))

  • Lee, Phil Woo;Lee, Hwa Hyung
    • Journal of Korean Society of Forest Science
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    • v.24 no.1
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    • pp.45-52
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    • 1974
  • This study was carried out to examine the subsitution possibility into water soluble amino resins instead of phenolic resin as a sizing material for the strength increase on the wet forming hardboard. The properties of hardboard, manufactured with amino-resins based urea, melamine, formaline, and methanol which were low priced domestic products, were examined in comparison with those of hardboard treated with phenolic resin. In this study by the results and discussions, it may be summarized as follows: 1. Amino-resins are able to be substituted for the phenolic resin as a good sizing material for strength increase in the manufacture of wet forming hardboard. Under the considerations of economic advantages and properties of hardboard, modified urea-melamine resin was given a best results. 2. The specific gravities of hardboard that were treated with phenolic resin was equal to that treated with modified amino type resin, and in case of urea-melamine resin, the specific gravity value were lowest among them. 3. The results of moisture contents were satisfied the standard which calls for 13 percent or below. There were no differences in moisture contents between hardboards, treated with melamine resin and modified urea-melamine resin but phenolic resin. The moisture contents of hardboard treated with phenolic resin was shown the lowest. 4. The water absorption of hardboard treated with phenolic resin was greater than those treated with amino resins, and to satisfy the standard of water resistance, the treatment of 2 percent paraffin wax emulsion was needed in this case. There were no differences in water absorptions between hardboards, treated with melamine resin and modified urea-melamine resin. To satisfy the standard of water resistance in this case the treatment of 1 percent paraffin wax emulsion was shown good results. 5. The differences among the flexural strength in using tested three adhesives were significant. The flexural strength were shown the signification by order of melamine resin, modified urea-melamine resin, and phenolic resin. In all cases to satisfy the standard of flexural strength, the treatment of 3 percent sizing materials for strength increase was needed.

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A Survey on the Perception and Usage Status of Dietitians in Food Service Business for Meat Products (단체급식소 영양사의 육가공품에 대한 인식 및 이용실태 조사)

  • Yong, Eun-Zu;Choi, Youn-Sang;Lee, Keun-Taik
    • Food Science of Animal Resources
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    • v.29 no.1
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    • pp.121-131
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    • 2009
  • This study attempted to investigate the perception and usage status for meat products of dietitians in the food service business in Seoul and Gangwon province. 32.8% of dietitians decided the menu reflecting the taste of students. Most of the dietitians (89.2%) checked the manufacture date of the processed meat products when they were supplied. To address the question as to whether they could distinguish the difference among ham, pressed ham, and sausage, most of them answered; 'can distinguish a little' (47.5%) or 'can't distinguish' (36.7%). The most frequently provided processed meat products were ham (33.9%), followed by sausage (21.7%). However, it is assumed that the dietitians might have mistaken the pressed ham for the classic ham. The most common frequency of the serving processed meat product in the food services was once a month (41.6%). Most desired aspect of quality improvement for the processed meat products was answered as 'hygiene/safety' (31.5%), and followed by 'higher quality' (26%). In conclusion, the improvement of the product quality and the strengthening of public information would be prerequisites for expanding the use of processed meat products in the food services and business-to-business (B2B) market in the future.

Methodologies for Enhancing Immersiveness in AR-based Product Design (증강현실 기반 제품 디자인의 몰입감 향상 기법)

  • Ha, Tae-Jin;Kim, Yeong-Mi;Ryu, Je-Ha;Woo, Woon-Tack
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.44 no.2 s.314
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    • pp.37-46
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    • 2007
  • In this paper, we propose technologies for enhancing the immersive realization of virtual objects in AR-based product design. Generally, multimodal senses such as visual/auditory/tactile feedback are well known as a method for enhancing the immersion in case of interaction with virtual objects. By adapting tangible objects we can provide touch sensation to users. A 3D model of the same scale overlays the whole area of the tangible object so the marker area is invisible. This contributes to enhancing immersion. Also, the hand occlusion problem when the virtual objects overlay the user's hands is partially solved, providing more immersive and natural images to users. Finally, multimodal feedback also creates better immersion. In our work, both vibrotactile feedback through page motors, pneumatic tactile feedback, and sound feedback are considered. In our scenario, a game-phone model is selected, by way of proposed augmented vibrotactile feedback, hands occlusion-reduced visual effects and sound feedback are provided to users. These proposed methodologies will contribute to a better immersive realization of the conventional AR system.

Simulation platform for living environment to ensure quality life (쾌적한 생활 설계를 위한 주거 및 사무실 시뮬레이터개발)

  • Park, Se-Jin;Kim, Chul-Jung;Kim, Si-Kyung;Mazumder, Mohammad Mynuddin Gani
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.8 no.4
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    • pp.853-860
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    • 2007
  • In this modern era, human beings lead their life in complex environment where there are lots of parameters such as temperature, light, smell, sound, visual stimulus etc. that play important role for quality life. These parameters affect physical and mental behavior of a human being immensely. To ensure quality life the demand for quality products is always associated with human emotion and sensibility. Due to human sensibility and emotion involvement with quality life, the design stages of any kind of product must include some certain features related with emotion and sensibility. The cues for optimizing artificial environment are the physiological responses of human in that environment. The conventional approach of environmental physiology is to measure the relationship between environmental physical parameters and human psychological parameters under artificial conditions. Using that approach we tried to design an artificial environment for our daily lives and activities associated with both physiological and psychological behavior. We developed the technique to present the mock environment and software to measure and evaluate sensibility physiologically or psychologically and a simulator to measure and evaluate sensibility that can be utilized for large scale industrial production and design of environment. Simulator to measure and analyze human sensibility (SMAS) was constructed, which was utilized to estimate human sensibility and to simulate living and office environment.

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