• Proceedings of the Korean Nuclear Society Conference
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• 1998.05b
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• pp.725-729
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• 1998

방사성 동위원소를 이용한 체외진단 측정법으로 RIA가 가장 널리 쓰여져 왔으나, 결합분획과 유리분획의 분리과정에서 오는 번거로운 단점을 개선하기 힘들었다. 1979년 Hart와 Greenwald에 의해 소개된 섬광근접측정법(Scintillation Proximity Assay, SPA)을 이용하여 RIA의 단점을 극복하고자 하는 연구가 시작되었다 주로 사용되는 방사성동위원소로 $^3$H, $^{125}$/I이 추천되는 핵종이며, 이 중에서 $^{125}$/I을 이용한 hCG(human chorionic gonadotropin) 체외진단법으로서 SPA의 기초연구를 수행하였다. SPA bead와 방사능 크기에 따라 측정되는 자연계수치의 증가와 hCG 표준물질을 농도별로 희석하여 유의성을 가지고 있는지 확인하였고, hCG 농도가 높은 것으로 판명된 환자의 혈청을 측정하여 임상적용의 가능성을 확인하였다.

• Korean Journal of Crystallography
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• v.3 no.1
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• pp.23-30
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• 1992

a-SiC crystals were grown on the (001) plane of a-SiC seed crystals by sublimation method to find effects of pressure-reduction rate of the crystal growth furnace own the growth rate and orientstion of grown SiC crystals. Pressure-reduction rate at the initial growth stage affected the crystallinity of grown SiC crystals. In case of high pressure-reduction rate, growth rate was high and 3csic polycrystalline was grown on the seed. On the other hand, low pressure-reduction rate caused the growth rate to be slow and 6H-SiC single crystal was grown on the seed. However, even after growing SiC for 2 hours under the condition in which.

• Journal of the Korean Society of Radiology
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• v.8 no.7
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• pp.389-395
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• 2014

The research was carried out to develop a animal model of malignant brain tumor for the researches in glioblastoma multiform (GBM) diagnosis and therapy. C6 cells were transplanted into the right striatum of SD rat using stereotactic instrument for the development. The developed animal model was verified by MRI and H&E stain assay of anatomicohistological examination. The MRI observations showed that the tumor developed at the injection site at the 7 days after glioblastoma inoculation. At 14 days post inoculation, the tumor grew to a large volume occupying almost a half of the right cerebral hemisphere. It was confirmed that the expression of excessive mitosis and pleomorphism in anatomicohistological examination. The developed animal model must be necessary and useful tool for the in vivo level research in the development of the new modality for the diagnosis and therapy of brain cancer.

• Journal of Korean Ophthalmic Optics Society
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• v.10 no.1
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• pp.53-61
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• 2005

In this study, we measured Near Point of Convergence(N.P.C) tests, Phoria tests using Von Grafe method and relative convergence tests on 138 men and 162 women, so a total of 300 subjects aged between 8~45 to examine the improvement of the fusion vergence through visual training and obtained as follows. 1. According to the results, the near point of convergence of 57 (19%) subjects were shorter than 7cm, and 243 (81%) were 7cm or longer, having a problem in convergence. After visual training, the number of subjects have the value shorter than 7 cm increased from 57 to 111 (37%), and the number of those have the value 7cm or longer decreased significantly form 243 to 189 (63%). 2. The results of the measure of lateral Phoria at far distance by Von Grafe method showed orthophoria 18 (6%), exophoria 198 (66%), esophoria 84 (28%). After phoria test, we examined the N.R.C and P.R.C test. The results showed that the hope finger was improved after V.T using B.l, B.O card. 3. The results of the measure of lateral Phoria at near distance by Von Grafe method showed orthophoria 6 (2%), exophoria 222 (74%), esophoria 72 (24%). After phoria test, we examine the N.R.C and P.R.C test. The results showed that the hope finger was improved after V.T using B.I, B.O card.

• Journal of Korean Ophthalmic Optics Society
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• v.18 no.3
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• pp.313-320
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• 2013

Purpose: This study compared the quantity of phoria for distance by new method with that by existing methods. Methods: For this study, it was selected to two existing phoria measurements, von Graefe and Maddox rod. And new method named "3D polarizing phoria measurement" was designed to measure the quantity of phoria using polarizing glasses and 3D display. Unlike existing measurement using polarized lens, newly considered method measured the quantity of phoria in condition removed perfect binocular fusion using field stop on apparatus and polarized lens. For using new method for distance, it was developed a phoria test chart. It supports three kinds of phoria measurements. Subjects were 12 (male 6, female 6). They had three phoria tests (1 sets) including new method. It was considered the effect of experimental order, so we tested all cases about experimental order. The number of cases was 6 sets, and the sample size in this experiment was 72 sets. For removing binocular fusion, lighting of the laboratory that was below 10 lx and the background color of phoria test chart was dark, RGB=(20, 20, 20). Results: Subjects were sorted into three groups. Samples with exophoria and orthophoria were 30 sets each, and those with esophoria were 12 sets. The quantity of phoria measured three tests differ from each other like "newmethod < von Graefe < Maddox rod", and there were statistically significant difference each other. Conclusions: This study has great significance in the sense that new method was the measurement with naturally removing binocular fusion without dizziness during the tests.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2012.11a
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• pp.54-56
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• 2012

본 논문에서는 이어폰 및 헤드폰 환경에서 스테레오 음원의 공간 정보를 보존하고 청취자의 엔벨롭감을 향상시키기 위한 Binaural 렌더링 기법을 제안하였다. 스테레오를 그대로 Binaural 렌더링 하지 않고 업믹스를 통해 스테레오 음원을 5.1채널의 음원을 생성한 뒤에 5.1패널 포맷의 스피커 위치 기반에 의해 렌더링 시킨다. 제안된 알고리즘은 두 가지 단계로 나뉘는데 첫 번째 단계로 스테레오 음원을 주성분 분석법( PCA )을 통하여 primary와 ambient신호로 각각 분리 하고 두 번째 단계로 분리한 primary와 ambient신호를 스테레오의 공간 정보에 기반 하여 머리전달 함수 (HRTF)를 이용하여 렌더링 한다. 또한 초기 잔향을 이용한 외재화 기법을 통하여 음원을 머리 밖에 정위시킴으로써 음원의 공간감을 향상시켰다. 제안된 방법은 주관적인 평가를 통하여 기존의 방법보다 우수한 성능을 보임을 확인하였다.

• PNF and Movement
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• v.7 no.4
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• pp.25-30
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• 2009

Purpose : The purpose of this study was to examine the effects of lower trunk muscles strengthening in athetosis children with cerebral palsy. Methods : One children with cerebral palsy participated in the case study. The age was 6 year. GMFM (gross motor function measure) was used to measure the functional movement ability. Lower trunk strengthening exercise were performed 3 times a week for 12 months. The measurements were taken before and after the exercise program. Results : In this study, the lower trunk strengthening exercise program was effective for gross motor functions. The children with athetosis type showed improvement in the Walking, Running & Jumping in GMFM. Conclusion : Therefore, the lower trunk strengthening exercise program was effective for the gross motor in athetosis type of cerebral palsy.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1992.05a
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• pp.34-34
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• 1992

심혈관계의 중추 조절작용과 고혈압 치료제의 작용기전을 규명하기 위한 연구의 한 단계로서 생체내 미세투석법(in vivo microdialysis)을 이용하여 후 시상하부의 국소부위에서 catecholamine들과 serotonin 및 그 대사체들의 세포와 농도의 변화를 정상혈압 횐쥐 (WKY)에서 관찰하고, 자연발생성 고혈압 횐쥐(SHR)에서 이들의 기준치를 비교하였다. 뇌정위 고정장치에 의해서 미세투석관을 후 시상하부에 위치시킨 후 링거액으로 관류하였다. 모노아민들과 그 대사체들은 고속액체 크로마토그라피와 전기화학 검출기률 이용하여 정량하였다. WKY에서 imipramine(50$\mu$M)의 관류에 의하여 norepinephrine의 농도가 유의하게 증가되었고, 또한 Pargyline (75mg/kg, i.p.)에 의하여 norepinephrine의 농도는 유의하게 증가된 반면에 DOPAC, HVA 및 5-HIAA는 감소하였다. WKY와 SHR에서 비교하였을때 norepinephrine, epinephrine, dopamine, serotonin의 농도는 차이가 없었으나 DOPAC, HVA, 5-HIAA의 농도는 SHR에서 유의하게 증가된 결과를 얻었다. 상의 결과들은 모노아민중에서 norepinephrine이 정상혈압 흰쥐의 후 시상하부에서 유리되는 주된 신경전달물질임을 시사한다. 또한 자연 발생성 고혈압 흰쥐의 후 시상하부에서 dopamine과 serotonin의 교체속도가 증가되었을 가능성이 큰 것으로 사료된다.

• Journal of Korean Ophthalmic Optics Society
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• v.10 no.3
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• pp.159-164
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• 2005

Accommodation and convergence is combination movement which is closely connected with each other. When one of them is stimulated, both of functions occur at the same time. Specially, the convergence by the accommodation's stimulation is called as accommodative convergence. That has excess or deficiency according to refraction state of eye. This study was performed by using both of Gradient method and Heterophoria method to 41 adults who have no any ophthalmic disease. 1. As the result of investigation about the distribution of heterophoria at distance, there were orthophoria of 5 subjects, exophoria of 32 and esophoria of 4. Exoporia occupied at the hightest rate. The distribution of heterophoria at near cover a wider range more than at distance. 2. When we measured the horizontal heterophoria amount in the state of relaxation of accommodation power of lens, exophoria amount increased in case of 38 subjects. 3. The person who has $4{\sim}6{\Delta}/D$ which conform to normal AC/A ratio occupied 27 subjects(66%) in Heterophoria method and 16(39%) in Gradient method, respectively.

• Radiation Oncology Journal
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• v.9 no.1
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• pp.53-58
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• 1991

From February 1987 through July 1990, the seventeen cases of inoperable intracranial arteriovenous malformation (AVM) were treated using 6 MV linear accelerator at the Division of Therapautic Radiology, Kang Nam 51. Mary's Hospital. Of seventeen cases, fourteen were male and three were female. Ages ranged from 10 to 51 years (median age of 25 years). The main symtoms were headache, epilepsy and hemiparesis in decreasing order of frequency. The middle cerebral artery is the most common origin of the feeding vessel $(41.2\%)$. Four were treated by conventionally fractionated radiation therapy (CRT, thirteen were treated by stereotactic radiosurgery (RS). duration or follow-up in CRT and RS group were 4 to 43 months (median 33 months) and 3 to 12 months (median 13 months), respectively. When the response was assessed by radiologic follow-up study, two of four CRT group showed minimal response. Of thirteen cases of RS group, two $(15.4\%)$ showed complete response, five $(38\%)$ partial response, two $(15.4\%)$ minimal response and four $(30.7\%)$ no response by the same assessment. There was no statistical significance in terms of follow-up period (p=0.22), size of lesion (p=0.82) and treated dose (p=0.05). Further accumulation of experience is recommended with proper case selection and sufficient follow-up period.