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Optimization of Transglucosylation Reaction of Stevioside (스테비오시드 당전이 반응의 최적화)

  • Kim, Jeong-Ryul;Yook, Cheol
    • Korean Journal of Food Science and Technology
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    • v.29 no.2
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    • pp.249-254
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    • 1997
  • Stevioside was transglucosylated to improve its sweetness. Eighteen conditions were tested using the tables of orthogonal arrays of $L_{18}\;(2^{1}{\times}3^{7})$. Statistical analysis showed that the transglucosylation rate was significantly affected by temperature, the ratio of co-substrate (maltodextrin) to stevioside, pH, DE of maltodextrin and concentration of stevioside, in their order. Optimum conditions selected for temperature, ratio of co-substrate to stevioside, pH and DE of maltodextrin were $80^{\circ}C$, 1.0, 6.0 and 15, respectively. Glycosyl-stevioside with 68% yield of transglucosylation was produced at the optimum condition and found to have better quality in sweetness than stevioside and rebaudioside A.

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A Novel Sub-image Retrieval Approach using Dot-Matrix (점 행렬을 이용한 새로운 부분 영상 검색 기법)

  • Kim, Jun-Ho;Kang, Kyoung-Min;Lee, Do-Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.3
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    • pp.1330-1336
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    • 2012
  • The Image retrieval has been study different approaches which are text-based, contents-based, area-based method and sub-image finding. The sub-image retrieval is to find a query image in the target one. In this paper, we propose a novel sub-image retrieval algorithm by Dot-Matrix method to be used in the bioinformatics. Dot-Matrix is a method to evaluate similarity between two sequences and we redefine the problem for retrieval of sub-image to the finding similarity of two images. For the approach, the 2 dimensional array of image converts a the vector which has gray-scale value. The 2 converted images align by dot-matrix and the result shows candidate sub-images. We used 10 images as target and 5 queries: duplicated, small scaled, and large scaled images included x-axes and y-axes scaled one for experiment.

Shape control of ZnO thin films and nanorods grown by metalorganic chemical vapor deposition (MOCVD 법으로 저온에서 성장한 ZnO 박막과 나노구조의 모양변화)

  • Kim, Dong-Chan;Kong, Bo-Hyun;Kim, Young-Yi;Jun, Sang-Ouk;An, Cheal-Hyoun;Cho, Hyung-Koun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.11a
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    • pp.21-21
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    • 2006
  • 21세기 정보통신 및 관련 소재의 연구방향은 새로운 기능성 확보, 극한적 제어성, 복합 및 융합이라는 경향으로 발전해 가고 있다. 반도체 기술 분야에서 현재의 공정적 한계를 극복하고 새로운 기능성을 부여하기 위해 나노 합성과 배열을 기본으로 하여 bottom-up 방식의 나노소자 구현이 큰 주목을 받고 있다. 나노선의 경우 나노 스케일의 dimension, 양자 제한 효과, 우수한 결정성, self-assembly, internal stress 등 기존 벌크형 소재에서 발견할 수 없는 새로운 기능성이 나타나고 있어 바이오, 에너지, 구조, 전자, 센서 등의 분야에서의 활용이 가능하다. 현재 국내외적으로 반도체 나노선으로 널리 연구되고 있는 재료는 ZnO, $SnO_2$, SiC 등이 중심이 되고 있다. 이중 ZnO 나 노선의 합성을 위해서는 thermal CVD, MOCVD, PLD, wet-chemical 등 다양한 방법이 사용되고 있다. 특히 MOCVD 방법에 의해 수직 정렬된 ZnO 나노막대를 성장할 수 있다. 이러한 나노막대는 MO 원료 및 산소 공급량을 적절히 제어함으로서 수직 배향 및 나노선의 구경 제어가 가능하며, 나노 막대의 크기 제어와 관련해서는 반응 관내의 DEZn 와 $O_2$의 양을 변화시켜 구조체의 크기를 수 십 ~ 수 백 나노미터의 크기로 제어할 수 있다. 본 연구는 이러한 ZnO 나노선의 성장과정에서 $210^{\circ}C$ 이하의 저온에서 성장한 ZnO 버퍼층을 이용해 나노구조의 형상을 제어하고자 하였다. 특히 ZnO 저온 버퍼층의 두께에 따라 나노막대의 직경변화, 수직배향성, 형상변화의 제어가 가능하였다. 나노막대의 특성 평가는 TEM, SEM, PL, XRD 등을 이용하여 구조적, 결정학적, 광학적 특성을 분석하였다.

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Heat/Mass Transfer and Friction Characteristic in a Square Duct with Various Discrete Ribs -In-Lined Gap Arrangement Ribs- (덕트내 요철의 단락위치 변화에 따른 열/물질전달 및 압력강하 특성 - 정렬 단락배열 요철 -)

  • Lee, Sei-Young;Choi, Chung;Rhee, Dong-Ho;Cho, Hyung-Hee
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.25 no.11
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    • pp.1640-1649
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    • 2001
  • The present study investigates the effects of various rib arrangements on heat/mass transfer in the cooling passage of gas turbine blades. A complex flow structure occurs in the cooling passage with rib turbulators which promote heat transfer on the wall. It is important to increase not only the heat transfer rates but also the uniformity of heat transfer in the cooling passage. A numerical computation is performed using a commercial code to calculate the flow structures and experiments are conducted to measure heat/mass transfer coefficients using a naphthalene sublimation technique. A square channel (50 mm $\times$ 50 mm) with rectangular ribs (4 mm $\times$ 5 mm) is used fur the stationary duct test. The experiments focus on the effects of rib arrangements and gap positions in the discrete ribs on the heat/mass transfer on the duct wall. The rib angle of attack is 60°and the rib-to-rib pitch is 32 mm, that is 8 times of the rib height. With the inclined rib angle of attack (60°), the parallel rib arrangements make a pair of counter rotating secondary flows in the cross section, but the cross rib arrangements make a single large secondary flow including a small secondary vortex. These secondary flow patterns affect significantly the heat/mass transfer on the ribbed wall. The heat/mass transfer in the parallel arrangements is 1.5 ∼2 times higher than that in the cross arrangements. However, the shifted rib arrangements change little the heat/mass transfer from the inline rib arrangements. The gap position in the discrete rib affects significantly the heat/mass transfer because a strong flow acceleration occurs locally through the gap.

Numerical Analysis of Heat Transfer of Aligned Wing Type Pin-Fin Array of Air Cooling Module with Various Fin Shapes for Electronic Packaging Application (날개형 핀-휜의 기하학적 형상이 전자기기 모듈 냉각용 공기냉각기의 유동 및 열전달에 미치는 영향)

  • Kim, Soo-Youn;Heo, Kyeon;Shin, Seok-Won
    • Clean Technology
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    • v.14 no.4
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    • pp.265-270
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    • 2008
  • In this study, the flow and heat transfer of the aligned pin-fin array of the air cooling module for electronic packaging application were numerically analyzed with various fin shapes. The geometric cross-sectional shapes of pin-fins considered in this study were ellipse, wing and circle. The fins had same cross-sectional area and height, but they had different surface areas. As the results, the surface area, the heat transfer coefficient, and the heat transfer performance of pin-fins greatly depended on their shapes. Of the three types of pin-fins, the wing type pin-fin with suitable shape produced the best heat transfer performance. This result implies that the cooling capacity of the pin-fin cooler can be significantly enhanced only by the change of fin shape without increasing air flow-rate or fin density.

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Photo Clustering using Maximal Clique Finding Algorithm and Its Visualized Interface (최대 클리크 찾기 알고리즘을 이용한 사진 클러스터링 방법과 사진 시각화 인터페이스)

  • Ryu, Dong-Sung;Cho, Hwan-Gue
    • Journal of the Korea Computer Graphics Society
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    • v.16 no.4
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    • pp.35-40
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    • 2010
  • Due to the distribution of digital camera, many work for photo management has been studied. However, most work use a sequential grid layout which arranges photos considering one criterion of digital photo. This interface makes users have lots of scrolling and concentrate ability when they manage their photos. In this paper, we propose a clustering method based on a temporal sequence considering their color similarity in detail. First we cluster photos using Cooper's event clustering method. Second, we makes more detailed clusters from each clustered photo set, which are clustered temporal clustering before, using maximal clique finding algorithm of interval graph. Finally, we arrange each detailed dusters on a user screen with their overlap keeping their temporal sequence. In order to evaluate our proposed system, we conducted on user studies based on a simple questionnaire.

THE INVESTIGATION OF MICROVASCULATURE CHANGES IN OSSEOUS REGENERATION BY GUIDED TISSUE REGENERATION PROCEDURE (골재생유도술에 의한 골재생시 미세혈관 구축 양상)

  • Choi, Du-Hee;Ryoo, Hyun-Mo;Shin, Hong-In
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.21 no.3
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    • pp.257-265
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    • 1999
  • To investigate the sequential changes in microvascular architecture and osseous regeneration during the bony healing after an application of the guided tissue regeneration method, we made artificial defects measuring $0.7cm{\times}0.3cm$ in size on femoral bones of rats measuring about 200gm and applied non-absorbable TEFE membrane at experimental sites but not at control sites. Then we observed the sequential changes and correlations between new vacuolation and bony regeneration using microvascular corrosion cast method and routine light microscopic observation at 1, 2 and 3 weeks after operation, respectively. The results showed that there were close relationships between regeneration of microvasculature and bone. In early phase, the invasion of granulation tissue at control sites delayed bony regeneration, however, in later phase, there was no remarkable differences in bony regeneration between control and experimental sites. The placement of barrier also affected in revascularization of regenerating bony defects. This is, the experimental sites showed parallel arranged nutritional vessels along long axis with well developed retiform plexus whereas the control revealed vertical invasion of microvasculature from outside of marrow space through bony defects which was also rearrange with time into parallel pattern with a vertical plexus but lesser organized than that of experimental sites. These findings suggest that the reconstruction of regenerating vasculature within the marrow cavity only may be sufficient and/or more be efficient in regeneration of bony defects.

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The effects of the correction exercise program combined with stretching and elastic band exercise on femoral intercondylar distance, Q-angle, plantar pressure in undergraduate with genu varum (탄성밴드운동과 스트레칭을 이용한 교정운동프로그램이 내반슬 대학생들의 무릎간 간격, Q-각 및 족압의 변화에 미치는 영향)

  • Yu, Byong-Kyu;Kim, Eun-Hye
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.3
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    • pp.2064-2072
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    • 2015
  • The aim of this study is to identify the effects of the correction exercise program on femoral intercondylar distance, Q-angle and plantar pressure in undergraduate with genu varum. A experimental study with a randomized controlled trial design was used. Thirty subjects with genu varum were allocated in two groups: the experimental group (n=15) or the control group (n=15). The experimental group conducted correction exercise program for 30 minutes a day, 5 times a week, for 6 weeks, while the control group did not perform any exercise. The correction exercise program group showed a significant decreased femoral intercondylar distance, plantar pressure of M 4, M 5 (Metatarsal 4, 5). Also the correction exercise program group significantly increased Q-angle, plantar pressure of Toe 2-5 and M 1, M 2, M 3 (Metatarsal 1, 2, 3) (Rt, Lt) (p<.05). Thus, we suggested that the correction exercise program may be suitable intervention to improve normal alignment in undergraduate with genu varum.

Catalyst-free 유기 금속 화학 증착법을 이용한 InN 나노구조의 성장

  • Kim, Min-Hwa;Lee, Cheol-Ho;Jeong, Geon-Uk;Mun, Dae-Yeong;Jeon, Jong-Myeong;Kim, Mi-Yeong;Park, Jin-Seop;Lee, Gyu-Cheol;Yun, Ui-Jun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.08a
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    • pp.264-265
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    • 2010
  • 최근, nanorod나 nanowire와 같은 1차원의 나노구조가 나노디바이스로 각광을 받고 있다. [1] 특히 InN는 3족 질화물 반도체 중 가장 작은 밴드갭 에너지와 뛰어난 수송 특성을 가지고 있어 나노디바이스로의 응용에 적합한 물질이다. [2] 그러나 InN는 큰 평형증기압을 가지므로 쉽게 인듐과 질소로 분해되는 특성이 있어 나노구조로의 성장이 쉽지 않음이 알려져 있다. [3] 최근 연구결과에 따르면, InN 나노구조는 금속 catalyst를 사용한 방법이나, 기판 위 패턴을 이용하여 성장하는 방법, 염소를 사용한 방법이 널리 쓰이고 있다. [4,5,6] 그러나 이 방법들은 의도치 않은 불순물의 원인이 되거나 다른 추가적인 과정을 필요로 한다는 문제점도 일부 가지고 있다. 본 연구에서는 catalyst-free 유기 금속 화학 증착법 (MOCVD)를 이용하여 $Al_2O_3$ (0001)면 위에 InN nanostructure를 성장하였다. InN nanostructure 성장 시 트리메틸인듐(TMIn)과 암모니아($NH_3$) 를 전구체로 사용하였으며, 캐리어 가스로는 질소를 사용하였다. 또한 모든 샘플의 성장시간은 60분으로 고정하였으나, 성장 시 온도의 의존성을 보기 위해 $680-710^{\circ}C$ 의 온도범위에서 성장을 진행하였다. 그 결과 InN는 본 실험에서 적용된 성장온도범위 내에서 온도가 증가함에 따라 초기에는 columnar구조로 성장된 박막의 형태에서 wall이 배열된 형태로 변화하며 결국 $710^{\circ}C$ 의 온도에서 nanorod로 성장하게 된다. 성장된 InN의 나노구조는 X-선 회절 측정법, 주사 전자 현미경 그리고 투과 전자 현미경을 이용하여 각각의 구조적 특성을 분석하였다. X-선 회절 측정법과 주사 전자 현미경을 통한 분석결과에서는 이들 nanorods가 대부분 c 방향으로 수직하게 정렬되어 있음을 확인 할 수 있었다. 또한, $690^{\circ}C$ 에서 60분간 성장된 InN의 wall 구조의 두께는 200 nm, 길이는 $2-2.5\;{\mu}m$로 관찰되었으며, $710^{\circ}C$에서 60분간 성장된 InN nanorod의 지름은 150 nm, 길이는 $3\;{\mu}m$ 정도로 관찰되었다. 이를 통하여 볼 때 성장 온도가 InN의 나노구조 형성 시 표면의 모폴로지변화에 중요한 변수로 작용함을 알 수 있다. 본 발표에서는 이러한 표면 형상 및 구조 변화가 성장온도에 따른 관계성을 가짐을 InN의 분해와 성장의 경쟁적인 관계에 의해 논의할 것이다.

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In vitro activity comparison of Erm proteins from Firmicutes and Actinobacteria (Firmicutes와 Actinobacteria에 속하는 세균들의 Erm 단백질 in vitro 활성 비교)

  • Jin, Hyung Jong
    • Korean Journal of Microbiology
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    • v.52 no.3
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    • pp.269-277
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    • 2016
  • Erm proteins methylate the specific adenine residue ($A_{2058}$, E. coli numbering) on 23S rRNA to confer the $MLS_B$ (macrolidelincosamide-streptogramin B) antibiotic resistance on a variety of microorganisms ranging from antibiotic producers to pathogens. When phylogenetic tree is constructed, two main clusters come out forming each cluster of Actinobacteria and Firmicutes. Two representative Erm proteins from each cluster were selected and their in vitro methylation activities were compared. ErmS and ErmE from Actinobacteria cluster exhibited much higher activities than ErmB and ErmC' from Firmicutes: 9 fold difference when ErmC' and ErmE were compared and 13 fold between ErmS and ErmB. Most of the difference was observed and presumed to be caused by N-terminal and C-terminal extra region from ErmS and ErmE, respectively because NT59TE in which N-terminal end 59 amino acids was truncated from wild type ErmS exhibited only 22.5% of wild type ErmS activity. Meanwhile, even NT59TE showed three and 2.2 times more activity when it was compared to ErmB and C, respectively, suggesting core region from antibiotic producers contains extra structure enabling higher activity. This is suggested to be possible through the extra region of 197RWS199 (from both ErmS and ErmE), 261GVGGSLY267 (from ErmS), and 261GVGGNIQ267 (from ErmE) and 291SVV293 (from ErmS) and 291GAV293 (from ErmE) by multiple sequence alignment.