• Tuberculosis and Respiratory Diseases
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• v.58 no.5
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• pp.459-464
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• 2005

연구 배경 : Adenosine deaminase (ADA)는 퓨린 (purine) 대사에 작용하는 효소로서 림 프구, 특히 T-림프구의 증식과 분화에 관여하며, 결핵성 흉수의 진단에 있어서 중요한 생화학적 표지자 중의 하나이다. 한편, 노인의 경우, T-림프구의 수와 기능의 감소에 의하여 면역 기능이 감소하는 것으로 알려져 있다. 이에 저자 등은 노인 결핵성 흉수 환자에서 흉수내의 ADA 수치가 젊은 환자에서보다 감소하는지를 조사하였다. 방 법 : 4년 동안 세브란스 병원에서 1) 흉수 결핵균 배양 양성 또는 2) 흉막 조직 검사상 결핵에 합당한 소견을 보여 결핵성 흉수로 진단받은 환자 80명을 대상으로 후향적으로 조사하였다. 65세를 기준으로 두 군으로 분류하였으며, 연령과 흉수 ADA 수치의 연관 관계를 독립 표본 t-검정 및 선형 회귀 분석을 이용하여 연구하였다. 결 과 : 80명의 환자 중 65세 이상은 21명 (26.3%)이었다. 흉수 내의 ADA 수치는 65세 이상 및 이하 군에서 각각 $71.2{\pm}27.6IU/L$, $68.5{\pm}5.8IU/L$ 이었다 (p=0.69). 선형 회귀 분석에서도 연령과 흉수 내의 ADA 수치는 상관 관계를 보이지 않았다 ($r^2=0.05$, p=0.59). 결 론 : 본 연구의 결과에 의하면, 결핵성 흉수의 진단에서 흉수 ADA 수치를 보조 지표로 사용하는 데 있어서, 노인환자에서도 젊은 환자와 동일한 임상적 유의성을 가지고 동일한 결정 수치 (cut-off value)를 적용할 수 있을 것으로 판단된다.

• Korea Real Estate Review
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• v.24 no.1
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• pp.91-104
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• 2014

This paper studied condo selection attributes that affected satisfaction, recommendation and revisitation, in particular, investigated gender and age differences. Research target is the group who revisited time-sharing condominium within one year. The paper seeks to understand factors that affect and contribute to customer satisfaction and intentions for reuse. This study model was analyzed by the basic statistical analysis, factor analysis, reliability analysis and multiple analysis, using SPSS 18.0 and AMOS 18.0. We found that 5 condo selection attributes that have significant affect on user satisfaction: facility, service, product, accessibility and expense. Furthermore it was evident that user satisfaction has a significant effect on condo recommendation and intentions of reuse. With regard to sex, for male users expense, accessibility and service had a significant effect on their satisfaction level, while for female users, product was most important. User satisfaction both have a significant effect on recommendation and intentions of reuse but for females this was more evident. Regarding the age, for 20~30 age band, service and product factor had a significant effect on user satisfaction in order, whereas, for the age band of over 40s, expense, product and facility factors were important. User satisfaction of both have a significant effect on recommendation and intentions of reuse. In the meantime user satisfaction of 20~30 age band had a bigger positive significant effect on recommendation and intentions of reuse than the age band over 40s.

• The Korean Journal of Food And Nutrition
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• v.13 no.3
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• pp.221-225
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• 2000

서울,충북지역의 주부 590명을 대상으로 시판김치의 사용실태를 설문 조사한 결과는 다음과 같다. 시판김치의 구매는 30대에서 많았고 고졸의 경우에 많았다. 직업 유무, 월수입, 주거 및 가족형태는 시판 김치 이용과 유의적인 차이를 보이지 않았지만 연령과 교육수준에 따라서는 유의적인 차이(P<0.05)연령이 낮을수록, 교육수준은 높을수록 시판김치를 이용하는 것으로 나타났다. 시판김치의 선호도는 배추김치가 73.2%로 높게 나타났고, 시판김치 구매 장소는 주로 대형 수퍼마켓을 이용하였으며, 1회 구매분량은 3포기를 구맹하는 경우가 가장 많았다. 구매 이유는 편리하기 때문과 가사와 자녀로 시간이 부족하여 구매하는 경우가 많았다. 또한 어떻게 담그는지 몰라서 구매하는 경우도 있었다. 제품 선택 동기는 주로 구맹 경험에 의해서 시판결치를 구입하였다. 광고를 보고 구매하는 경우도 있었고 재료나 점원의 권유에 의해서 구매하는 경우도 있었다. 응답자들이 가장 맣이 지적한시판 김치으 개선점은 가격이었다. 가격이 비싸다고 생각하는 경구가 많았다. 그밖에 위생명, 맛의 다양성, 분량과 용기의 개선도 필요하다고 생각하는 경우가 있었다. 향후 시판김치 구매 여부에 대해서는 73.2%가 긍정적으로 응답하여 앞으로도 시판김치를 구매할것으로 나타났다. 이상의 결과를 보면 상품화 된 김치의 이용은 젊은 세대뿐만 아니라 교육수준의 향상에 의해 주부들의 라이프 스타일이 식생화에도 반영되기 때문에 계속증가할 것으로예측된다. 그러므로 본 연구의 결과를 토대로 하여 가격면, 위생면, 맛의 다양성, 분량과 용기 등에 있어서도 한 단꼐 개선된 고품질 김치의 생산이 요구된다고 볼 수 있다.

• 한국노년학
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• v.39 no.2
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• pp.363-388
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• 2019

This study examined the influence of subjective age on subjective well-being and depression, and the mediating effect of meaning in life. A survey of 394 adults aged 40 or older completed a questionnaire concerning subjective age perception, meaning in life, subjective well-being, and depression. The main results are summarized as follows. First, the analysis of subjective age according to the sociodemographic variables showed that middle-aged and elderly people, who were highly educated and had good perceived health status, felt themselves younger than their counterparts did. Second, a young subjective age had a positive effect on meaning in life and subjective well-being while negatively influencing depression. Third, meaning in life significantly mediated the relationship among subjective age, subjective well-being, and depression. In other words, the younger the middle- and old-aged adults perceived themselves, the more meaning they found in life, which led to higher subjective well-being and lower depression. These findings suggest that, as people get older, perceiving themselves as younger than their chronological age can protect their mental health, and meaning in life plays an important role in the process.

• Journal of the Korean Arthroscopy Society
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• v.5 no.1
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• pp.36-40
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• 2001

Purpose : We analyzed the effectiveness of arthroscopic diagnosis and treatment for painful hip in young patients caused by labral tear or synovial disease. Materials and Methods : From May 1997 to June 1998,7 young patients who had painful hip were diagnosed by history, physical examination, radiologic studies(including plain films, MRI, MR arthrogram) and arthroscopy. We treated the lesions by arthroscopic surgery and followed up for more than 1 year. Results : On arthroscopy, the labrum was torn in 6 cases and chronic synovitis was found in 1 case. After arthroscopic surgery, pain was eliminated completely in 5 cases and mild pain remained in 2 cases, respectively. But there was no limitation in activities of daily living and athletic performances. Conclusion : Arthroscopy is effective in diagnosis and treatment of labral tears and synovial diseases in young patients.

• Journal of agricultural medicine and community health
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• v.31 no.2
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• pp.145-156
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• 2006

Objectives: Health behaviors are related to each other, or they may be essentially dependent upon each other. Hence the overall health behaviors of a given population could be better described in terms of health lifestyle patterns. This paper tried to classify such patterns in a sample population and suggest the socioeconomic and demographic characteristics of each groups. Methods: A sample population comprised of 2,775 adults who reported their health behaviors in a public health survey were classified according to their smoking, drinking, diet, and exercise related pattern of behaviors. Clustering analysis was used to classify them. Results: Six health lifestyle patterns were identified. Individuals in the passive lifestyle cluster (48.3%) had no active health promoting activities, but did avoid risk taking health behaviors. 24.8% of the sample (Health promoting lifestyle) had an overall healthy lifestyle. 13.5% of the sample were in the smoking cluster, and 8.4% were in the alcohol drinking cluster. The hedonic lifestyle (4.5%) was characterized by heavy smoking, alcohol drinking and poor diet and exercise. 0.7% of the sample (Smoking-Drinking lifestyle) had heavy smoking and drinking, but good diet and exercise. Each group could be characterized by sex, age, and income. Conclusions: A population sample of Seoul adults were successfully clustered into six health lifestyles. The socioeconomic and demographic characteristics were suggested for the characterization of the each health lifestyle groups. We can approach to a certain target population with specific strategy.

• Korean Journal of Culture and Social Issue
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• v.12 no.5_spc
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• pp.149-167
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• 2006

Korean society is rapidly changing to aging society comparing the other industrialized countries, however, the studies of elderly driver's driving behavior and accidents are not enough in Korea for elderly driver's accident prevention. This study focused on the elderly driver's psychological effects on elderly driver's driving behavior and traffic accidents; carefulness and aberrant driving behavior. - Elderly driver's traffic accidents The high percentage of elderly driver's accidents occurs in intersections and when turning left. There was a significant difference of the opponent vehicle's speed when left turn, between elderly driver and young driver; the elderly driver choose the higher speed of opponent vehicle than young driver when left turning. This result means that elderly driver has some problems with deciding the vehicle's speed and gap acceptance(Sunyeol Lee, Soonchul Lee, and Inseok Kim, 2006)(Table 1). - Carefulness and driving confidence In order to understand elderly driver's carefulness, this study compared the elderly driver's driving confidence. Driving confidence was consisted of 4 factors; environment of traffic condition, safe driving, driving ability and attention. Elderly driver's confidence was lower than young driver's. Elderly driver in high driving confidence group, showed longer driving history and they were tend to commit violations more frequently than elerly driver in low driving confidence group. Young driver, whose driving confidence level was high answered more driving history, annual mileage, the frequency of committing traffic violation and the experience of accident within lats 5 years(Soonchul Lee, Juseok Oh, Sunjin Park, Soonyeol Lee and Inseok Kim, 2006)(Table 2). This study examined the total time required until deciding to turn left in the no traffic signal intersection between elderly driver and young driver. The result showed that the time of elderly driver was significant longer than young driver(Sunyeol Lee et al, 2006)(Table 3). - Elderly driver's aberrant behavior Driver behavior Questionnaire(DBQ) was measured to understand the aberrant behavior; violation, error and lapse. The tend of aberrant behavior was observed by aging(Sunjin Park, Soonchul Lee, Jonghoi, Kim and Inseok Kim, 2006). Elderly driver's DBQ score was lower than young driver's(Table 4). Elderly and young driver showing longer driving history were in low DBQ score group. Elderly driver had high error score and young driver had high violation score. Young driver's aberrant driving behaviour was associated with annual mileage and the frequency of committing traffic violation. Elderly driver's aberrant driving behaviour was associated with annual mileage and experience of accident. Especially elderly driver whose violation, error and lapse score was high answered more committing experience of accident within last 5 years.

• The Journal of the Petrological Society of Korea
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• v.27 no.2
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• pp.97-104
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• 2018

The U-Pb isotopic and rare earth element compositions of zircon were measured using a SHRIMP from a tonalitic gneiss sample DE43 in Daeijak Island, central Korea. Zircon crystals, up to ${\sim}300{\mu}m$ in diameter, rarely contain thin overgrowth rims. In contrast to Paleoproterozoic cores, the $^{206}Pb/^{238}U$ ages of $256{\pm}23Ma(1{\sigma})$, and $221{\pm}7Ma(1{\sigma})$ were yielded from two spot analyses on the overgrowth rims of zircon. The rims are geochemically characterized by low Th/U ratios (<0.01) and strongly depleted light rare earth elements. The Permian-Triassic apparent ages of zircon are consistent with the $^{208}Pb/^{232}Th$ ages dated from allanite ($227{\pm}7Ma(t{\sigma})$) in the same sample within uncertainties, indicating an equilibrium growth of allanite and zircon at ~227 Ma. On the other hand, the younger $^{208}Pb/^{232}Th$ and $^{206}Pb/^{238}U$ ages ($213{\pm}4Ma(t{\sigma})$ and $186{\pm}9Ma(t{\sigma})$, respectively) of allanite may result from Pb loss due to the infiltration of alkali fluids from Late Triassic and Jurassic granitoids nearby.

• Development and Reproduction
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• v.13 no.4
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• pp.227-237
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• 2009

Recently, adipose mesenchymal stem cells (AdMSC) that are similar to bone marrow MSC and blood derived MSC are thought to be another source for stem cell therapy. However, the diseases that can be applied for stem cells therapy are age-dependent degenerative diseases. Accordingly, the present study investigated the growth and differentiation potential to neural cells of human AdMSC (hAdMSC) obtained from aged thirty, forty and fifty. The growth of cells and cell viability were measured by passage and neural differentiation of hAdMSC was induced in neural differentiation condition for 10 days. Our results demonstrated that cell number, viability and morphology were not different from hAdMSC by age and passage. Immunofluorescence analysis of neural cell marker (TuJ1, NSE, Sox2, GFAP or MAP2) demonstrated no significant differences in neural cell differentiation by age and passage. As the number of passage was increased, the mRNA level of MAP2 and Sox2 was decreased in hAdMSC from age of 50 compared to hAdMSC from age of 30. In conclusion, the present study demonstrated that ability of neural cell differentiation of hAdMSC was maintained with ages, suggesting that autologous stem cells from aged people can be applied for stem cell therapy with age-dependent neural disease with the same stem cell quality and ability as stem cell derived from young age.

• Journal of Nutrition and Health
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• v.46 no.5
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• pp.410-417
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• 2013

Caloric restriction is recognized as one of the best treatment options for obesity, and is associated with changes in body composition. The purpose of this study was to determine the influence of age in caloric restriction in overweight and obese women. In this caloric restriction study, nutrient intake of 61 women was evaluated using food records written by subjects for three days. Body composition and metabolic risk factors were assessed before and after caloric restriction. Blood levels of lipids, glucose, leptin, and adiponectin were measured. Visceral fat and subcutaneous fat were evaluated using bioimpedance analysis. General linear models (GLM) identified the independent effects of age after co-varying baseline weight and difference of energy intake. Weight, fat mass, visceral fat, subcutaneous fat, and blood pressure showed a significant decrease by caloric restriction of 452 kcal/day. The percent changes in weight, visceral fat, and subcutaneous fat were -4.5%, -12.0%, and -8.2%, respectively, after caloric restriction. The percent changes of weight, visceral fat, and subcutaneous fat showed an independent association with age co-varying baseline weight and difference of energy intake. Decreased change in percent of leptin by caloric restriction also showed an association with age. Changes in body composition and leptin by caloric restriction showed an independent association with age. This may indicate greater difficulty in achievement of change of body composition as well as greater obesity-related metabolic risk with aging. Therefore, caloric restriction considering age should be recommended for effective dietary treatment in overweight or obese women.