• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2018.11a
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• pp.1-2
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• 2018

최근 포스트휴머니즘은 오늘날 북아메리카와 서유럽을 비롯하여 동아시아 학문 공동체에서 가장 뜨거운 화두가 되고 있다. 포스트휴머니즘은 4차 산업혁명의 핵심인 NBIC기술의 융합으로 사유와 논의가 가능해진 개념이다. 포스트휴머니즘는 기존의 휴머니즘 그리고 트랜스 휴머니즘과 밀접한 관계를 맺는다. 서구 휴머니즘 전통의 핵심은 17세기 합리주의 정신에 이르러 하나의 절정을 이룬다. 논자는 오늘날 뜨거운 화두인 포스트휴먼 논의의 발단은 서구 모더니티로부터 비롯된다고 본다. 기술의 융합적 발전이 인간, 인간의 본질, 인간의 정의를 변화시키고 있다는 점에 주목한다. NBIC으로 대표되는 과학기술융합은 인간을 변화시키고 있음은 분명하다. 우리는 그것을 트랜스휴머니즘으로 정의한 바 있다. 이제 인류문명은 트랜스휴머니즘을 넘어서 각종 보철술이 인간의 몸을 대신하는 포스트휴먼으로 진화 가능한 단계로 접어들었다. 기술의 급진적인 발전으로 기존의 근대적 재현과 표상, 상징체계가 바뀌는 것이다. 미셀 푸코는 '이를 두고 '근대적 인간의 소멸'을 예견한 바 있다. (1) 우리는 이 시점에서 이러한 급진적이고도 근본적인 변화를 촉발하는 '기술혁명' 시대에 '인간은 무엇인가', 인간적인 적인 것은 무엇인가'에 관한 이른바 인간학적 지평에 대환 논의가 긴급하다고 판단한다.

• The Korean Journal of Nuclear Medicine
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• v.37 no.6
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• pp.402-417
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• 2003

Purpose: To evaluate the use of monoclonal antibody (MoAb) as a carrier of the receptor-binding ligand the receptor mediated uptake into liver and subsequent metabolism of $^{111}In-labeled$ galactosylated MoAb-chelator conjugates were investigated and compared with those of $^{111}In$ labeled MoAb. Materials and Methods : T101 MoAb, $IgG_2$ against human lymphocytic leukemic cell, conjugated with cyclic DTPA dianhydride (DTPA) or 2-p-isothiocyanatobenzyl-6-methyl-DTPA (1B4M) was galactosylated with 2-imino-2-methoxyethyl-1-thio-${\beta}$-D-galactose and then radiolabeled with $^{111}In$. Biodistribution and metabolism study was peformed with two $^{111}In-conjugates$ in mice and rats. Results: $^{111}In-labeled$ T101 and its galactosylated conjugates were taken to the liver by the time, mostly within 10 min. However DTPA conjugate was retained longer in the liver than the 1B4M conjugate (55% vs 20% of injected dose at 44 hr). During this time, the radiornetabolite of DTPA conjugate was excreted similarly into urine (24%) and feces (17%). The radiometabolite of 1B4M was excreted primarily into feces (68%) rather than urine (8%). Size exclusion HPLC analysis of the bile and supernatant of liver homogenate showed two peaks the first (35%) with the retention time (Rt) identical to IgG and the second (65%) with Rt similar to free $^{111}In$ at 3 hr post-injection for the 1B4M conjugate, indicating that the metabolite is rapidly excreted through the biliary system. in contrast to DTPA conjugate, the small $^{111}In-DTPA-like$ metabolite was the major radioindium component (90%) in the liver homogenate as early as 3 hour post-injection, but the cumulative radioindium activity in feces was only 17% at 44 hour, indicating that the metabolite from DTPA conjugate does not clear readily through the biliary tract. Conclusion: The galactosylation of the MoAb conjugates resulted in higher hepatocyte uptake and enhanced metabolism, compared to those without galactosylation. Metabolism of the MoAb-conjugates is different between compounds radiolabled with different chelators due to different characteristics of radiometabolites generated in the liver.

• Journal of the Korean Society for information Management
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• v.28 no.2
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• pp.97-115
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• 2011

A large and reliable citation database is necessary to identify and analyze citation behavior of Korean researchers in science and technology. Korea Institute of Science and Technology Information (KISTI) built the Korea Science Citation Database (KSCD), and have provided Korea Science Citation Index (KSCI) and Korea Journal Citation Reports (KJCR) services. In this article, citing behavior of Korean scientists on Korean journals was examined by using the KSCD that covers 459 Korean core journals. This research dealt with (1) statistical numeric information of journals in KSCD, (2) analysis of document types cited, (3) ratio of domestic to international documents cited and ratio of citing different disciplines, (4) analysis on immediacy index, peak time, and half-life of cited documents, and (5) analysis on impact of journals based on KJCR citation indicators. From this research, we could find the immediacy citation rate (average 2.36%), peak-time (average 1.7 years) and half-life (average 5.2 years) of cited journals in Korea. We also found that the average journal self-citation rate is more than 50% in every field. In sum, citing behavior of Korean scientists on Korean journals was comprehensively identified from this research.

• The KIPS Transactions:PartD
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• v.11D no.5
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• pp.1123-1132
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• 2004

Successful project planning relies on a good estimation of the manpower required to complete a project. The good estimation can be derived from Rutnam's Rayleigh Model or Phillai et al.'s Gamma Model. These models only can be applied for the projects which the need of manpower is increased exponentially and the highest of manpower is required at the end of development phase. However, in a practical project, most manpower is required during development phase and a small amount of manpower is assigned during maintenance phase. In addition, the Waterfall Model and Unified Process only can be adopted for development phase. So the current development environments cannot be adopted into the existing manpower distribution models which the highest manpower is required at the end of development phase. This paper suggests an appropriate model for development phase to solve this problem. First, the appropriate manpower distribution for development phase of the Waterfall model was derived from Putnam's manpower distribution and then manpower distribution of development phase was derived for Unified Process. After comparing the required manpower of two Processes, total manpower distribution is similar each other even though the required manpower and task is different for each point of development phase. From this result, a unified model is derived and it can be applied for both development processes.

• Korean Journal of Ichthyology
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• v.23 no.1
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• pp.21-29
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• 2011

Expression analysis of development-related genes was conducted using differential screening of 6-month-old [18M(-), 6M-18M] specific and 18-month-old [6M(-), 18M-6M] specific subtracted cDNA libraries constructed by subtractive hybridization using skeletal muscle of 6- and 18-month-old dark-banded rockfish Sebastes inermis. A total 202 cDNA clones displaying different expression levels in each stage were obtained; among them, 32 clones showing up-regulation were finally selected for further expression analysis. We sequenced the clones and analyzed individual sequences. Genes expressed specifically in 6-month-old skeletal muscle were identified as myosin, adenylate kinase, calsequestrin, dystrobrevin beta, and diphosphate kinase-Z1. Genes showing strong expression in 18-month-old rockfish were identified as desmin, TGFBR2 (transforming growth factor-beta receptor), muscle-type creatine kinase, and cathepsin D. Expression of these genes was checked further in 6-18-30-42 month-old dark-banded rock fish. Rapid reduction of expression was observed in dystrobrevin beta and diphosphate kinase. However, expression of creatine kinase (muscle type) and cathepsin D increased as dark-banded rockfish grew, and remained even after 18 months. The results reported here demonstrate that genes related to muscles contract are expressed at an early stage of development, and genes controlling energy in muscles are predominantly expressed at a late developmental stage.

• The Korean Journal of Zoology
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• v.31 no.1
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• pp.11-20
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• 1988

A comparison between two species of Hyla japonica and H. suweonesis in Korea was carried out to clarify their morphological, genetic and ecological differences, to estimate presumed divergent time between them, and to elucidate their probable process and mechanism of speciation. The results are as follows; 1.The breeding season of H. japonica was earlier than that of H. suweonensis about one and half months. 2.H.japonica was distributed all over the country, while H. suweonensis was restricted in Kyonggi plains. 3.On the extemal morphometric characters, differences were hardiy seen between two species. But on the discriminant function analysis, there was apparent differences between them. 4.Genic variation based on 24 loci showed that H. japonica populations were about two fold more variable than that of H. suweonensis populations. 5.Genetic relatedness between two species was rather remote (S =0.520, D=0.634) 6.Their presumed divergent time was estimated to be about three and a quarter mfllon years. It is presumed that H. suweonensis was originated from H. japonica during the period of late pleocene and early pleistocene. 7.Premating isolating mechanisrns (breeding season, mating call, and microhabitat segregation) may be operating to prevent gene ifow between them.

• Journal of Korean Society of Forest Science
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• v.33 no.1
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• pp.59-67
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• 1977

Seasonal changes in free arginine concentration in Pinus radiata buds were studied in four clones from May, 1974 to June, 1975. The buds were from the tips of first order branches which had flowered the previous year, and the significant findings were as follows: (1) In general, arginine concentration in the buds of the four clones showed the highest peaks from December to March, a period spanning the time of flower initiation, and the lowest levels in Angust and September. (2) The timing of individual arginine peaks during the period of flower initiation matched roughly the timing of initiation of several female cone clusters, as determined from Clone 7 which characteristically initiates three cycles of female cones on its leading shoot. (3) The heavy-flowering clones showed higher arginine concentration than ther poorer flowering ones, especially at the time of flower initiation.

• The KIPS Transactions:PartD
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• v.11D no.3
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• pp.495-508
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• 2004

Recently, in content-based music information retrieval systems, to enhance the response time of retrieving music data from large music database, some researches have adopted the indexing mechanism that extracts and indexes the representative melodies. The representative melody of music data must stand for the music itself and have strong possibility to use as users' input queries. However, since the previous researches have not considered the musical composition forms, they are not able to correctly catch the contrast, repetition and variation of motif in musical forms. In this paper, we use an index automatically constructed from representative melodies such like first melody, climax melodies and similarly repeated theme melodies. At first, we expand the clustering algorithm in order to extract similarly repeated theme melodies based on the musical composition forms. If the first melody and climax melodies are not included into the representative melodies of music by the clustering algorithm, we add them into representative melodies. We implemented a prototype system and did experiments on comparison the representative melody index with other melody indexes. Since, we are able to construct the representative melody index with the lower storage by 34％ than whole melody index, the response time can be decreased. Also, since we include first melody and climax melody which have the strong possibility to use as users' input query into representative melodies, we are able to get the more correct results against the various users' input queries than theme melody index with the cost of storage overhead of 20％.

• 한국해양학회지
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• v.25 no.2
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• pp.96-105
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• 1990

To study the fish larval community in the coastal waters of the mid-east Yellow sea, samples were collected with Bongo net at 13 stations between Chonsu Bay and Keum Estuary from July, 1985 to June, 1986. total of 45 taxa of fish larvae were occurred. the predominant species was Enedrias fangi accounting for 45.2% of the total abundances, and the next were Engraulis japonicus (27.5%), sardinella zunasi (10.6%), Callionymidae spp. (4.6%), Sillago japonica (3.0%), Favonigobius gymnauchen (1.9%), and Acentrogobius pflaumii (1.8%). These 7 taxa constituted 94.6% of the total abundances. The monthly abundances showed two peaks in July and January. Species diversities were very low from January to April when E. fangi predominated.

• Journal of KSNVE
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• v.1 no.2
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• pp.121-128
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• 1991

In order to use viscoelastic materials efficiently for noise and vibration control, or th qualify newly developed materials, knowledge of the Young' s modulus and loss factor is essemtial. These material properties, the so-called complex Young' s modulus, are frequently treated as dynamic charicteristics because of their dependence upon the frequency. Many techniques have been developed and verified for measuring complex Young' s modulus of viscoelastic materials. Among them, the impedance method is preferable in order to obtain the frequency information in detail. In this method, a cylindrical or prismatic specimen is excited into longitudinal harmonic vibration at one end, the other being fixed, and the resulting force is measured at the driving or fixed end. The amplitude ratio of the two signals and phase angle between them are then used to compute the material properties using various mathematical models. In this paper, the impedance method is investigated theoretically and experimentally. A way to determine the specimen geometry which is most appropriate for the identification of complex Young' s modulus using the lumped mass model is presented and discussed. Then experimental results supporting the theoretical predictions are presented.