• Applied Chemistry for Engineering
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• v.30 no.4
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• pp.509-511
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• 2019

Hydrazine derivatives used in fine chemicals, pharmaceuticals and cosmetics can be synthesized by reduction reaction from diazonium derivatives. The reduction method using $SnCl_2$ facilitates the reaction conversion, but the use of $SnCl_2$ is limited when residual heavy metals are issued in the final product. For the conversion of protected (2-hydroxyphenyl)diazonium derivatives into its hydrazine derivatives in Ramalin preparation process, the reduction method was developed by using $NaHSO_3$. In this study, the effect of steric hindrance according to the protected 2-hydroxygroupinphenyldiazonium derivatives was found, and linear C1~C5 alkyl groups for the hydroxy protection were preferable during the diazonium reduction reaction. Considering the economical efficiency and industrial production for the preparation of Ramalin, a variety of protecting groups were investigated. As a result, 2-(allyloxyphenyl)hydrazine was obtained with 85% yield and 99.7% purity when the hydroxy protecting group was used as an allyl group that could be easily deprotected.

• Journal of Convergence for Information Technology
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• v.12 no.1
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• pp.180-188
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• 2022

Goal of this study is to identify effect of Oral Motor Facilitation Technique(OMFT) on feeding development, tube weaning of PWS baby. Subject was 8months old PWS girl. 2 times of OT, 1 times of OMFT per weeks were provided from July, 2020 to June, 2021. Feeding development and skills was increased and could eat food by mouth after OMFT treatment. Especially, she could eat food by her mouth after 3mts of OMFT and age-appropriated food intake, chewing function, drinking by straw was increased. Through this case study, early detecting and treatment for feeding development of PWS is very important. OMFT is good treatment protocol for increasing feeding development and oral motor skills of PWS.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.7
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• pp.2991-2999
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• 2012

In this study, a survey was carried out on 150 parents who have regular children attending integrated childcare centers in J area, through March 2 to March 10, 2012, with the purpose of figuring out the Effects of Attitudes toward Disabled Children on Integrated Childcare Attitudes in Regular Parents. The results are summarized as follows. First, the effect of attitudes toward disabled children on regular integrated childcare attitudes showed that cognitive and emotional factors had a statistically significant positive effect on regular attitudes. Second, the effect of attitudes toward disabled children on children's activities and teachers' concerns for integrated childcare showed that cognitive and behavioral factors had a statistically significant positive effect on children's activities and teachers' concerns. Third, the effect of attitudes toward disabled children on behavioral problems of integrated childcare showed that cognitive, emotional and behavioral factors had a statistically significant positive effect on behavioral problems. As for findings stated as above, there was a difference in integrated childcare attitude depending on regular parents' attitude toward disabled children. This implies that there is a difference in cognitive and emotional attitudes toward disabled children in regular parents, acting as positive factors that raise the integrated childcare attitude for the improvement of perception on these factors. Consequently, for the integrated childcare, both disabled children and regular children should admit each other's diversity and accept different each other's existence, and the perception change of parents, who try to respect and learn together, should be preceded.

• Korean Journal of Psychosomatic Medicine
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• v.5 no.2
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• pp.185-194
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• 1997

A comparison was made regarding illness behavior among patients with somatoform disorders, depressive disorders and psychosomatic disorders. The subjects consisted of out-patients with somatoform disorders(N=52), depressive disorders(N=52) and psychosomatic disorders(N=51). illness behavior was assessed by illness Behavior Assessment Schedule and the questionnaire about help-seeking behavior. The patients with somatoform disorders and psychosomatic disorders more often affirmed the presence of somatic disease, were more likely to have phobia of disease, had more preoccupation with ideas of disease and more frequently shopped around oriental clinics than the patients with depressive disorders. The patients with somatoform disorders more often attributed its cause to physical factors, less often attributed the origin of affective disturbance to psychological causes, showed Less depression and irritability, and were less likely to accept psychiatric treatment recommended by other physicians than depressive patients. The patients with somatoform disorders were more likely to report having been told that they suffered from a mild illness than those with psychosomatic disorders. The patients with somatoform disorders with psychological problems tended to inhibit expression of their emotion. Female patients with somatoform disorders more often affirmed the presence of psychological disorder and attributed its cause to psychological factors than male ones. These results suggest that in illness behavior, patients with somatoform disorders are different from depressive patients, whereas the former patients are similar to psychosomatic patients except the discrepancy between therapists and patients regarding evaluation of their symptoms. Thus, it is emphasized that first, therapists need to approach patients with somatoform disorders somatically with understanding of their underlying need to deny psychological problems, followed by either psychological or biopsychosocial approach.

• Journal of Digital Convergence
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• v.15 no.2
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• pp.441-449
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• 2017

This study applied an occupation-centered transition program to adults, aged 18 years or more, with intellectual disabilities and residing in a local community, and examined the effects of the program on participants' self-efficacy and social participation. To obtain basic data for the program, 44 adults with intellectual disability were divided into two groups: the experimental group, to which an occupation-centered transition program was applied, and the control group, to which the program was not applied. A self-efficacy scale and the K-Community participation indicators (CPI) were used to assess self-efficacy and social participation, respectively. The results showed that the experimental group showed a greater increase in self-efficacy than the control group (p<0.05). Similarly, a greater increase in the CPI scores was observed in the experimental group than in the control group. The changes in the experimental group were significant (p<0.05), but those in the control group were not. These results suggest that an occupation-centered transition program can improve self-efficacy and social participation in adults with an intellectual disability.

• LOGISTICS
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• v.2 no.4 s.6
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• pp.62-67
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• 2004

지난 5월 1일부로 동유럽 10개국이 유럽연합(EU)에 가입했다. 동유럽 10개국이 EU에 가입했다는 것은 두 가지 측면에서 역사적 장애물을 제거하는 계기가 될 것이다. 하나는 사회주의체제를 벗어나 자본주의 체제로 편입되는 체제전환을 추구해왔으니 구소련이 주도하던 바르샤바동맹국으로서 몸에 베었던 의식과 체제의 잔재를 씻어내기 어려웠으며 이러한 잔재들은 동유럽 국가들의 경제$\cdot$사회 발전을 가로막는 역사적 장애요인으로 작용해 왔다. 따라서 EU가입은 이러한 역사적 장애요인을 극복하는 중요한 계기가 될 것으로 예상된다. 동유럽 10개국은 모든 사회$\cdot$경제 거래를 EU기준에 맞춰야 하며, 도로$\cdot$철도$\cdot$해운$\cdot$항공 등 물류부문에서도 EU의 기준을 충족시켜야 하는 ‘EU 공동체 확적영역’을 수용해야 한다. 따라서 동유럽 물류시장은 EU가입 이후 경제 및 교역발전에 따른 양적 팽창이외에 물류관련 기준과 거래관행이 개선되는 질적 발전도 가능하게 될 것이다. 우선 역내 통관절차가 단순해지는 등 사람, 자본, 화물의 이동이 자유화됨으로써 물동량이 크게 늘어날 것으로 예상되고 또한 동유럽 국가들은 EU로부터 운송 인프라 개발 및 현대화에 필요한 경제적 지원도 받게 된다. 한국해양수산개발원(KMI)은 ‘EU 가입 동유럽 물류시장의 특징과 시사점’이라는 현안분석을 통해 이같이 밝히고 우리나라 물류기업이 동유럽 시장에 진출하는 경우 제조업과 동반진출하고 현지업체와의 제휴관계를 모색하는 것이 바람직하다는 대응방향을 제시했다. 동 현안분석 내용을 요약$\cdot$정리한다.

• Journal of the Korean Wood Science and Technology
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• v.37 no.3
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• pp.274-286
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• 2009

Lignocellulosic biomass is the most abundant raw material for bioconversion in many country. However the high costs for pretreatment and enzymatic hydrolysis currently deter commercialization of lignocellulosic biomass, especially wood biomass which is considered as the most recalcitrant material for enzymatic hydrolysis mainly due to the high lignified structure and the nature of the lignin component. Therefore, overcoming recalcitrance of lignocellulosic biomass for converting carbohydrates into intermediates that can subsequently be converted into biobased fuels and biobased products is the primary technical and economic challenge for bioconversion process. This study was mainly reviewed on the research trend of pretreatment with lignocellulosic biomass in bioethanol production process.

• The Journal of the Convergence on Culture Technology
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• v.6 no.2
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• pp.131-137
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• 2020

The purpose of this study is to seek ways to support the independence of the disabled with disabilities based on community care. First, the main contents of the de-institutionalization policy as a new paradigm for the welfare of the disabled are reviewed.The implications of caring were considered.Third, we reviewed cases of foreigners who have been carrying out community care and examples of projects to support disabled people with disabilities as a pilot project.Lastly, on the basis of the above, the central government and local governments suggested ways to support independence of the disabled with community care-based disability.

• Child Health Nursing Research
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• v.21 no.4
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• pp.331-338
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• 2015

Purpose: This study was done to identify differences in the life transition process of parents caring for children with autism according to parents' socio-demographic characteristics. Methods: Participants were 194 parents caring for children with autism. Data were collected from December 2013 to February 2014 through self-report questionnaires, and analyzed using descriptive statistics, t-test, ANOVA with SPSS/WIN 20.0. Results: Mean scores for despairing or accepting phases were higher than those for denying or wandering phases in the life transition process. According to parents' gender, educational level, and job, there were some significant differences in the denying and wandering phases. Differences in denying phase by education (p=.033), job (p=.004) were significant. Respondents with higher educational level, and having a job showed a lower level of denying than other respondents. Wandering phase differed significantly by gender (p=.009) and job (p=.001). Mothers and those who did not have a job showed a higher level of wandering than fathers and those who had a job. However, there was no difference in the despairing or accepting phases. Conclusion: The life transition phase of parents with autistic children needs to be assessed to provide differentiated and intensive support program and help them move to the accepting phase.

• Clinical and Experimental Pediatrics
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• v.48 no.4
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• pp.425-432
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• 2005

Purpose : Polyglutamine diseases are a group of diseases caused by the expansion of a polyglutamine tract in the protein. The present study was performed to verify if polyglutamine disease transgenic Drosophila models show similar dysfunctions as are seen in human patients. Methods : Polyglutamine disease transgenic Drosophila were tested for their climbing ability. And using genetic methods, the effects of anti-apoptotic gene bcl-2 and chemical chaperones on neurodegeneration were observed. Also, spinocerebellar ataxia 2 (SCA2) transgenic Drosophila lines were generated for future studies. Results : Expanded forms of spinocerebellar ataxia 3 (SCA3) transgenic protein causes characteristic locomotor dysfunction when expressed in the nervous system of Drosophila but the anti-apoptotic gene bcl-2 shows no evidence of ameliorating the deleterious effect of the expanded protein. However, Glycerol, a chemical chaperone, seemed to reduce the toxicity, at least in the eyes of the transgenic flies. The level SCA2 expression is too weak in the transgenic SCA2 Drosophila for evaluation. Conclusion : SCA3 transgenic Drosophila show ataxic behavior as observed in human patients. Chemical chaperones such as glycerol may prove beneficial in this class of genetic disease, which has no current method of cure.