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Effect of Monascus koji on Blood Pressure and Serum Cholesterol Composition of SHR by Chronic Dietary Administration (홍국 장기투여가 SHR의 혈압 및 혈중 콜레스테롤 조성에 미치는 영향)

  • 류미라;김은영;한진수
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.3
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    • pp.464-468
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    • 2003
  • The antihypertensive and cholesterol- lowering effects of Monascus koji (M. koji) prepared with Monascus ruber IFO32318 were examined in spontaneously hypertensive rats (SHR). Control was fed a normal diet and groups I, II or III were fed diets containing 0.03%, 0.1% or 0.3% M. koji for 8 weeks, respectively. After 8 weeks, all animals were fed normal diets in the following 2 weeks. The blood pressure of rats fed M. koji added diets were significantly attenuated as compared with control and the diet containing high concentration of M. koji had a tendency of stronger antihypertensive effect. These differences lasted throughout the experimental period when they were fed experimental diet. For 2 weeks after the 8 weeks of experimental diet all groups were fed the same normal diet and the differences of blood pressure caused by M. koji disappeared. In rats fed the M. koji added diet, the serum total cholesterol (TC), HDL cholesterol (HDL-C), LDL cholesterol (LDL-C) were not differed compared with control, but VLDL cholesterol (VLDL-C) was significantly lowered. M koji also significantly decreased serum risk factors, both TC/HDL-C ratio and non HDL-C/HDL-C ratio. Consequently, it is suggested that M. koji may play an important role to attenuate hypertension and to improve serum lipid Profiles.

Characteristics of Fluorescent Organic Matter and Amino Acids Composition in the East Sea (동해의 용존유기물 형광특성 및 아미노산 조성에 관한 연구)

  • 박용철;손승규
    • 한국해양학회지
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    • v.30 no.4
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    • pp.341-354
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    • 1995
  • Fluorescence characteristic and amino acids composition of organic matter were determined from extracted seawater samples at eight stations in the East Sea of Korea. Organic compounds have been extracted onto C-18 Sep-Pak cartridges. Three dimensional excitation/emission fluorescence contouring of extracts showed two markedly distinct characterized fluoroscopies representing protein-like biomacromolecule and humic-like geomacromolecule. Protein-like biomacromolecule showing fluorescence maxima at 280 nm/330 nm (excitation/emission) were abundant in the surface mixed layer and then apparently decreased below the thermocline at most stations. It suggests that source of biomacromolecule is comely related with vigorous biological synthetic activity in the surface layer and bacteria decompose its biologically labile components near the thermocline and in the deeper layer. On the other hand, humiliate geomacromolecule showing fluorescence maxima at 330 nm/430 nm (excitation/emission) were low in the surface mixed layer implying photochemical oxidation and then increased below the thermocline at most stations. It suggests that geomacromolecule might be transformed by condensation of bio-refractoryorganic fraction after decomposition of biomacromolecule and particulate organic carbon derived from the surface mixed layer. HPLC measurements of amino acids showed similar composition between seawater and extracted organic macromolecule after hydrolysis. Glycine, serine and alanine were predominant, accounting for more than 50% of total amino acids. Dissolved free amino acids of seawater were more abundant in the surface layer(0.7∼1.8 uM) than the deeper layer (0.2∼0.4 uM). D/L racemic ratio of alanine of extracted organic matter showed lower value in the surface layer than the deeper layer. It suggests that biomacromolecule predominant in the surface layer is relatively young, rapidly recycling and biologically labile.

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Anticancer Effect of Erythronium japonicum Extract on ICR Mouse and L1210 Cells with Alteration of Antioxidant Enzyme Activities (얼레지 추출물의 ICR 마우스와 L1210 암세포에 대한 항암작용과 그에 따른 항산화효소 활성변화)

  • Shin, Yoo-Jin;Jung, Dae-Young;Ha, Hye-Kyung;Park, Sie-Won
    • Korean Journal of Food Science and Technology
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    • v.36 no.6
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    • pp.968-973
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    • 2004
  • Effects of Erythronium japonicum methanol extract on ICR mouse with induced abdominal cancer and L1210 cells were studied. Administration of methanol extract ($10-100\;{\mu}g/20\;g$ body weight) prolonged life by 47.8% and decreased number of L1210 cells with $IC_{50}\;of\;54.6\;{\mu}g/mL$ after 3 days culture, whereas little effect was observed against normal lymphocytes (<6% compared to 83.2% of L1210 cells under the same condition). Increased SOD and GPx enzyme activities, and remarkably augmented generation of ${O_2}^-$ ion in L1210 cells by E. japonicum extract, implied that reactive oxygen species including ${O_2}^-$ ion, might have participated in L1210 cell death

Estimation of Optimal Stocking Rate of Earthworm Populations (지렁이 개체군의 최적 사육밀도 추정)

  • Lee, Ju-Sam;Noh, Jin-Hwan;Park, Sang-Soo;Lee, Hee-Choong
    • Korean Journal of Organic Agriculture
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    • v.20 no.3
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    • pp.369-383
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    • 2012
  • This experiment was carried out to investigate the optimal stocking rate of earthworm populations grown under different stocking rates. The stocking rate in terms of ratio of biomass of earthworms to biomass of feeds(organic resources) is an important factors for biomass productivity of earthworms and vermicast production. The different stocking rates were 1:16(S-1), 1:32(S-2), 1:48(S-3) and 1:64(S-4), as the ratios of biomass of earthworm to biomass of organic dairy cow manure, respectively. The stocking rate of 1:32(S-2) and 1:46(S-3) were obtained a higher values on increasing rates and conversion efficiency of organic matter to earthworm biomass than other stocking rates. Thus, a stocking rates of 1:32 and 1:46 estimated an optimal stocking rates for maximum biomass productivity of earthworms. A stocking rate of 1:16(S-1) showed a significantly highest values of vermicast production and ratios of vermicasts during the rearing periods.($$P{\leq_-}0.05$$) A stocking rate of 1:48(S-3) showed a highest values of the number of cocoons and vermicasts production per earthworm biomass among the treatment ($$P{\leq_-}0.05$$) The contents of nitrogen, available phosphorus, cation exchange capacity and exchangeable cations of vermicasts tended to increase with stocking rate and rearing progressed. Vermicasts have a great deal of potential for crop production and protection in sustainable organic cropping systems.

The Settlement of Complication in Water Resources Project (수자원 사업분야의 갈등해결 방안)

  • Park, Joo-Bum;Kim, Man-Ki
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.1645-1649
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    • 2007
  • 수자원사업분야 특히, 댐건설사업은 사업시행지역이 유역의 상류인 반면 댐건설의 편익은 주로 하류지역에서 발생하기 때문에 상류지역을 중심으로 극심한 반대가 상존하고 있는 실정이다. 상 하류 지역 주민과 지자체 간에도 댐건설에 대한 입장이 상충되고, 이런 갈등을 정치적으로만 해결하려고 함으로써 갈등의 해결보다는 오히려 새로운 갈등의 원인이 되기도 한다. 또한, 갈등해결을 위한 사회적 합의와 그 합의 결과에 대한 승복의 문화가 정착되지 않은 우리나라에서 갈등해결은 매우 어려운 실정이다. 지난 7년 동안 사회적인 찬반 논란의 중심에 있었던 한탄강홍수조절댐건설에 따른 갈등의 전개과정과 해결노력을 평가 분석하여 봄으로써 향후 수자원사업 분야의 갈등해결에 많은 도움이 될 것으로 본다. 한탄강홍수조절댐은 지난 1999년 결정 이후 2004년 1월부터 11월까지 대통령자문 지속가능발전위원회와 이해 당사자가 참여하는 중재적 갈등조정과정을 거쳤으나, 조정 결과에 대해 승복하지 않음으로써 당사자 합의에 의한 최초의 갈등조정 시도가 무산되었으나 그 해결 노력은 정당하게 평가 받을 만하다. 이후 한탄강댐건설사업은 정부에서 국무총리를 위원장으로 하는 임진강유역홍수대책특별위원회를 구성하여 이해 당사자를 배제하고 관련학회의 전문가 등으로 1년 동안 검증평가한 결과 2006년 8월 한탄강홍수조절댐과 천변저류지로 최종 대안을 제시하였으나, 댐건설 반대지역에서는 아직도 완전히 승복하고 있지 않는 실정이다. 결국 갈등을 해결하기 위해서는 사업계획 수립단계부터 이해 당사자들이 참여하는 협의회 운영으로 절차적 정당성을 확보하고, 한탄강홍수조절댐 갈등해결에 있어서 부족했던 사회적 합의와 승복문화가 정착되도록 제도적인 장치보완과 함께 성숙된 시민의식의 전환이 있어야만 할 것으로 사료된다. 외적으로 하천 유사량 산정과 관련된 많은 경험식들이 제시되고 있다. 하지만, 외국의 충적하천에 기초하여 개발되어진 유사량 공식들을 우리나라 하천에 무분별하게 적용하는 것은 위험스러우며, 유사량 산정 결과의 신뢰성을 높이기 위해서는 무엇보다 우리나라 하천의 지형, 수리, 수문학적 요소들이 유사 특성에 미치는 영향을 알아야 한다. 그러므로, 본 연구에서는 실측을 통한 유사량 값을 하천의 지형, 수리, 수문학적 요소들과 비교 분석하여우리나라 하천에 맞는 유사특성을 알아보고, 기타 총유사량산정 공식을 이용하여 실측한 유사량과 비교 분석하고자 한다.호강유역의 급격한 수질개선을 알 수 있다.世宗實錄) $\ulcorner$지리지$\lrcorner$(地理志)와 동년대에 동일한 목적으로 찬술되었음을 알 수 있다. $\ulcorner$경상도실록지리지$\lrcorner$(慶尙道實錄地理志)에는 $\ulcorner$세종실록$\lrcorner$(世宗實錄) $\ulcorner$지리지$\lrcorner$(地理志)와의 비교를 해보면 상 중 하품의 통합 9개소가 삭제되어 있고, $\ulcorner$동국여지승람$\lrcorner$(東國與地勝覽) 에서는 자기소와 도기소의 위치가 완전히 삭제되어 있다. 이러한 현상은 첫째, 15세기 중엽 경제적 태평과 함께 백자의 수요 생산이 증가하자 군신의 변별(辨別)과 사치를 이유로 강력하게 규제하여 백자의 확대와 발전에 걸림돌이 되었다. 둘째, 동기(銅器)의 대체품으로 자기를 만들어 충당해야할 강제성 당위성 상실로 인한 자기수요 감소를 초래하였을 것으로 사료된

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Study on Derivation of Fourth-Order GIUH and Revision of Initial State Probability (4차 하천에서의 GIUH의 유도 및 초기확률의 보정에 관한 연구)

  • Ham, Dae-Heon;Joo, Jin-Gul;Jun, Hwan-Don;Kim, Joong-Hoon
    • Journal of Korea Water Resources Association
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    • v.41 no.2
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    • pp.229-239
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    • 2008
  • This study is to derive the fourth-order Geomorphologic Instantaneous Unit Hydrograph (GIUH), driven for only third-order basin, for the application of GIUH to various types of basin. The second, third, and fourth order GIUHs were compared for various topographical conditions. The results showed lower peak runoff and later peak time in GIUH with higher stream order. Initial state probability was estimated from a function of geomorphologic parameters such as area ratio and bifurcation ratio for the application of GIUH. However, initial state probabilities and early parts of the GIUHs have negative values for many basins due to the inherent errors in the parameters. Initial state probability was calculated by area ratio of direct drainage using ArcView GIS 3.2 model to solve the problem. GIUHs were estimated for three basins, Sanganmi, Byeongcheon, and Sangye, using the above suggested method, and the results showed that the method is free of the problem.

Decomposition of CO2 Emissions in the Manufacturing Sector : An International Comparative Study for Korea, UK, and USA (제조업 부문의 이산화탄소 배출 요인분해: 한국·영국·미국의 국제비교 연구)

  • Han, Taek Whan;Shin, Wonzoe
    • Environmental and Resource Economics Review
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    • v.16 no.3
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    • pp.723-738
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    • 2007
  • This paper draws some implications from Logarithmic Mean Weight Divisia Method (LMWDM) on the sources of $CO_2$ emission changes in the manufacturing sectors of Korea, UK, and USA. The sources of change in industrial $CO_2$ emission of a country, as manifested by production scale factor, structural factor, and technical factor, summarizes the forces behind the change in $CO_2$ emissions in each country's manufacturing sector. There are three observations. First one is that Korea's emission is increasing while USA and UK are experiencing reduction or stabilization of $CO_2$ emission in the manufacturing sector. Second implication is that the technical factor affecting $CO_2$ emission in Korea does not help much, or even hinder, the reduction of $CO_2$ emissions, comparing to USA and UK. Third one, which is the combined result of the first and the second one, is that Korea's increasing trend in aggregate $CO_2$ emission throughout the periods in consideration is mainly due to the failure in technical progress, or the deterioration in the structure of within subcategories, or both. The policy implications is clear. The obvious prescription is to launch a nation-wide policy drive which can revert these adverse trends.

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Analyzing the Spatial Change of Urban Green Spaces with Cell Based Spatial Metrics : A Case Study of Daegu (화소 기반 공간메트릭스를 이용한 도시 녹지의 공간적 변화 분석: 대구시를 사례로)

  • Seo, Hyun-Jin;Jun, Byong-Woon
    • Journal of the Korean association of regional geographers
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    • v.23 no.1
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    • pp.136-150
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    • 2017
  • This study analyzed the spatial change of urban green spaces in Daegu from 1989 to 2009 using cell based spatial metrics. To do so, the conversion process of land covers during the past 20 years was explored using a land cover change detection matrix. The synoptic analysis with a moving window sampling strategy was conducted to quantify cell based spatial metrics related to size, shape, cohesion, and diversity and to explain the spatial change at the local level. Difference maps were then generated by subtracting the 1989 maps of spatial metrics from the 1998 maps and the 1998 maps from the 2009 maps. The gradient analysis was performed to identify the directional change of spatial metrics along an urban development axis in Daegu. The results from this study show that urban green spaces in Daegu during the past 20 years have been gradually fragmented around the new town housing development districts such as Dalseong-gun, Seongseo, and Ansim. Forests were most prominently fragmented in the Hwawon area while most rapidly in the Chilgok area. Grasslands were largely fragmented in many areas due to the decrease in size and cohesion indices and most fragmented in the Ansim area. The spatial pattern of the decreased and fragmented urban green spaces identified by this study can be used as a base data for establishing the environment-friendly urban development strategy in Daegu.

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Effect of Foliar Spray of Urea on Urease Activity in various Plant Leaves (요소엽면시비(尿素葉面施肥)가 Urease활성(活性)에 미치는 영향(影響))

  • Hong, Jong-Uck;Lee, Hyo-Sa
    • Applied Biological Chemistry
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    • v.24 no.1
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    • pp.15-20
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    • 1981
  • Changes of urease activity in plant leaves following foliar application of urea were investigated with soybean, rye, tomato, radish and cabbage which were actively growing in a field. In this experiment, the procedure of the enzyme assay included incubation of the reaction mixture at $60^{\circ}C$ for 3 hr in order to inactivate heat unstable enzmes which may utilize ammonia produced by urease. The leaves with urea application showed somewhat higher urease specific activities for 2-4 days immediately after the foliar spray as compared with controls. The most difference of the specific activies between urea treatment and control was usually observed 2 days after urea application regardless of the plants. The difference of the specific activities disappeared completely 4 or 5 days following urea treatment. Protein contents in the leaves of soybean and tomato were increased for about 5 days after urea treatment, while no significant difference was found with rye, radish and cabbage. Urea application showed slightly lower ammonia concentration in the leaves which had higher urease activities. These results suggest that foliar spray of urea is very effective when nitrogen supply is required for rapid growth.

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Measurement of an Isoelectric Point and Softness of a Zwitterionic Surfactant (양쪽성 계면활성제의 등전점 및 유연력 측정에 관한 연구)

  • Lim, Jongchoo;Kim, Jisung;Mo, Dahee;Lee, Jinsun
    • Applied Chemistry for Engineering
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    • v.23 no.1
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    • pp.112-118
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    • 2012
  • In this study, physical properties of synthesized DE7-OSA82-AO and DEP52-OSA82-AOQ82 zwitterionic surfactants were measured such as critical micelle concentration, surface tension, interfacial tension, contact angle and viscosity. Phase behavior study was also performed. The dual function characteristics of a zwitterionic surfactant were investigated by determining an isoelectric point, which was attained using zeta potential measurements and QCM (quartz crystal microbalance) experiments. The isoelectric point of DE7-OSA82-AO surfactant determined by the zeta potential measurement and QCM experiment was about 7.2 and 7.4, respectively. On the other hand, the isoelectric point of DEP52-OSA82-AOQ82 surfactant determined by the zeta potential measurement and QCM experiment was about 10.9 and 11.0, respectively. The frictional property measured using an automated mildness tester showed that DE7-OSA82-AO surfactant can provide a good softening effect at an acidic or neutral condition. On the other hand, DEP52-OSA82-AOQ82 was found to provide a good softening effect to a fabric surface at a pH below its isoelectric point of 11.