• Title/Summary/Keyword: 전신계수

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Effect of Glycopyrrolate on Cardiovascular System in Dogs Sedated with Medetomidine-Midazolam Combination (개에서 Medetomidine과 Midazolam 병용 투여 시 Glycopyrrolate가 심맥관계에 미치는 영향)

  • Han, Dae-Kyung;Shin, Beom-Jun;Lee, Jae-Yeon;Jee, Hyun-Chul;Park, Ji-Young;Kim, Myung-Cheol;Jeong, Seong-Mok
    • Journal of Veterinary Clinics
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    • v.26 no.4
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    • pp.317-323
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    • 2009
  • This study was performed to evaluate the effect of intravenous administration of glycopyrrolate on cardiovascular and respiratory system in dogs given intravenous medetomidine (20 ${\mu}g$/kg) and intramuscular midazolam (0.3 mg/kg) (MM). Prior to administration of MM, glycopyrrolate was administered intravenously at doses of 5 ${\mu}g$/kg (Gly-5), 10 ${\mu}g$/kg (Gly-10) or 20 ${\mu}g$/kg (Gly-20), respectively. For the control group saline was administered intravenously. In the cardiovascular system, HR, BP, RAP, PAWP, CI, SI, SVR, and PVR were measured. RR, $V_T$, $P_{ETCO2}$, and arterial blood gas analysis were measured for respiratory system. Although rapid and satisfied depth of sedation was obtained by MM, life-threatening bradycardia, the outstanding side-effect on cardiovascular system in dogs were observed. This combination also decreased CO and increased SVR, RAP, and PAWP significantly. The bradycardia could be prevented in all the glycopyrrolate treated groups, but tachycardia was observed in Gly-10 and Gly-20 groups. Significant increases in blood pressure were shown in glycopyrrolate treated groups. Also, tachycardia depends on dose of glycopyrrolate, compensating the CO. However, these were not fully reserved. In conclusion, MM combination could induce rapid and satisfied depth of sedation but was not the suitable method for the deep sedation of dogs with cardiovascular or circulatory problems.

Estimating the Yield of Potato Non-Mulched Using Climatic Elements (기상자료를 이용한 무피복 재배 감자의 수량 예측)

  • Choi, Sung-Jin;Lee, An-Soo;Jeon, Shin-Jae;Kim, Kyeong-Dae;Seo, Myeong-Cheol;Jung, Woo-Suk;Maeng, Jin-Hee;Kim, In-Jong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.59 no.1
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    • pp.89-96
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    • 2014
  • We aimed to evaluate the effects of climatic elements on potato yield and create a model with climatic elements for estimating the potato yield, using the results of the regional adjustment tests of potato. We used 86 data of the yield data of a potato variety, Sumi, from 17 regions over 11 years. According to the results, the climatic elements showed significant level of correlation coefficient with marketable yield appeared to be almost every climatic elements except wind velocity, which was daily average air temperature (Tave), daily minimum air temperature (Tmin), daily maximum air temperature(Tmax), daily range of air temperature (Tm-m), precipitation (Prec.), relative humidity (R.H.), sunshine hours (S.H.) and days of rain over 0.1 mm (D.R.) depending on the periods of days after planting or before harvest. The correlations between these climatic elements and marketable yield of potato were stepwised using SAS, statistical program, and we selected a model to predict the yield of marketable potato, which was $y=7.820{\times}Tmax_-1-6.315{\times}Prec_-4+128.214{\times}DR_-8+91.762{\times}DR_-3+643.965$. The correlation coefficient between the yield derived from the model and the real yield of marketable yield was 0.588 (DF 85).

Effect of Chicory (Chicorium intybus L.) Root Diameter on Chicon Growth Characteristics (치커리 근경이 치콘 생육에 미치는 영향)

  • Seo, Hyun-Taek;Won, Jae-Hee;Jeon, Shin-Jae;Kang, Ho-Min
    • Journal of Bio-Environment Control
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    • v.20 no.2
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    • pp.139-143
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    • 2011
  • This study was conducted to investigate correlation between external factors of chicory root and chicon fresh weight, whereby, to provide basic information of external yardstick of producing standardized chicon. For correlation between external factors (root diameter, root weight) of chicory root and chicon fresh weight were highly correlated. The relationship between external factors (root diameter, root weight) of chicory root and chicon fresh weight, root diameter was strongly affecting chicon fresh weight due to significant at its regression coefficient ($6.06^{***}$). In order to verity this correlation, the root diameter (x) of chicory that were 3 different varieties were based on the 4 different root diameter treatments, such as x ${\leq}$ 30 mm, 30 < x ${\leq}$ 40 mm, 40 < x ${\leq}$ 50 mm and x > 50 mm. The chicon production increased as root diameter increased and the chicon fresh weight, chicon width, and the number of leaves increased as well. Therefore, the measure of root diameter of chicory instead of the internal factors (carbohydrate, and so on.) can be used to predict the chicon fresh weight.

A Study on Bioassay of Tritium($^{3}H$) Radioacitivity (三重水素($^{3}H$) 放射能의 生理分析에 關한 硏究)

  • 황선태;오필재;김원식
    • Journal of Korean Society for Atmospheric Environment
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    • v.3 no.1
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    • pp.27-33
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    • 1987
  • The environment and biological studies of tritium have been carried out in the advanced countries since the mid 1950's. In the case of a potential tritium exposure, the usual procedure is trifium bioassay (as HTO) in human urine in order to determine the amount of tritium deposited in the body called tritium body burden. The maximum permissible body burden(MPBB) of tritium in total body is about $30{\mu}Ci/{\ell}$ for body tissue. In the bioassay, the most common investigation level for detection of tritium in urine is 1/10th of MPBB. For this bioassay project, the first priority is given to obtaining a quench correction curve. This consideration is necessary because of the variability in color of human urine specimens. Quenching effect in this case mainly is caused by the absorption of scintillation light flashes by the urine sample. By the least squares method on the statistical basis, an estimated formula for quench correction curve was determined to be Y = 0.771 + 1.836 ${\tmes}10^{-4}$X, where the efficiency(Y) was ranged from about 12% to 31% in the liquid scientillation counting. In this paper, a brief theory concerning the biological half-life of tritium and the retention formula to apply to systematically distributed tritium are described.

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The Effect of Extracapsular Cataract Extraction and Posterior Chamber Lens Implantation on Intraocular Pressure (백내장적출술 및 인공수정체삽입술이 안압에 미치는 영향)

  • Cha, Soon-Cheol;Lee, Kyoo-Won
    • Journal of Yeungnam Medical Science
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    • v.11 no.2
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    • pp.277-283
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    • 1994
  • We studied the change in intraocular pressure (IOP) in 15 consecutive cataract patients who underwent extracapsular cataract extraction and posterior chamber lens implantation between Feb. 1993 and Apr. 1993 to evaluate the effect of this surgery on postoperative IOP. To evaluate the clinical usefulness of non-contact tonometer, the intraocular pressures were measured with Kowa non-contact tonometer (TM-2000, Japan) as well as Goldmann applanation tonometer. There was a decrease in IOP of $3.4{\pm}2.9$mmHg (p<0.00l) 3 months after this surgery and the intraocular pressure differences between pseudophakic eyes and contralateral phakic eyes at 3 months postoperatively were $2.4{\pm}3.8$mmHg (p<0.05). The correlation coefficient between non-contact tonometer and Goldmann tonometer was 0.8876 (p=0.001) in the postoperative 76 eyes. Therefore, our results suggest that extracapsular cataract extracion and posterior chamber lens implantation alone can be a useful surgical method in cataract patient with ocular hypertension, and non-contact tonometer was relatively accurate in measuring the postoperative intraocular pressure.

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Isolation of Cymbidium mild mosaic virus (Cymbidium mild mosaic virus의 분리동정)

  • Chang M. U.;Doi Y.;Yora K.
    • Korean journal of applied entomology
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    • v.17 no.3 s.36
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    • pp.131-138
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    • 1978
  • A virus named Cymbidium mild mosaic virus(Cy MMV), was mechanically transmitted to Chenopodium amaranticolor from the leaves of Cymbidium with mild mosaic symptoms. The virus was cultured in C. amaranticolor, in which it produced local chlorotic and ring spots, followed by systemic vein clearing with distortion. CyMMV infected 7 out of 35 species of plants. In C. amaranticolor juice infectivity was lost by heating at $90^{\circ}C$ for 10 miuntes, and by aging at$20^{\circ}C$ for 60 days, and by diluting at $10^{-6}$ when bioassayed on C. amaranticolor. CyMMV was not transmitted by Myzus persicae. The virus was purified after clarification of homogenized C. amaranticolor leaf tissues with chloroform, by differential centrifugation followed by sucrose density gradient centrifugation. Electron microscopic examination of purified preparation showed spherical particles of 28nm in diameter. The UV absorption spectrum of purified preparation was typical of u nucleoprotein (max. at 261nm. min. at 243nm), and showed 260/280=1.72 and max/min=1.26. The value of the sedimentation coefficient of the virus was S20.w=126. In gel-diffusion tests, CyMMV antiserum reacted with CarMV, but not with any of four other viruses (BBWV, CRSV, CMV, TBRV) having similar particles and properties in vitro. In ultra-thin sections of CyMMV infected tissues, a large number of virus particles were found in the cytoplasm of mesophyll cells and in xylem vessels.

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Comparative Evaluation of Cardiac Output using Echocardiography in Beagle Dogs (비글견에서 심초음파를 이용한 심박출량 측정에 관한 비교 연구)

  • Park, Kitae;Yeon, Seongchan;Lee, Heechun
    • Journal of Veterinary Clinics
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    • v.29 no.5
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    • pp.384-390
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    • 2012
  • Echocardiographic measurements of cardiac output, including the modified Simpson's method, Automated Contour Tracking(ACT) method, and left ventricular outflow method are well described methods of evaluating cardiac function due to its reliability and the benefits of its non-invasive technique in human medicine. The purpose of this study was to evaluate the accuracy of an echocardiography estimate of cardiac output in isoflurane-anesthetized beagle dogs and was to compare the ACT method to the other methods used in measurement of cardiac output. In healthy beagle dogs, cardiac output results by echocardiography estimate methods showed an excellent correlations with those by the thermodilution method (The modified Simpson's method : r = 0.815, $r^2=0.665$, y = 0.434x + 0.311 ; ACT method : r = 0.86, $r^2=0.748$, y = 0.391x + 0.242 ; ventricular outflow method : r = 0.691, $r^2=0.478$, y = 0.593x + 0.242). Among the results obtained, the ACT method showed the highest correlation coefficient. In conclusion, our study demonstrated that echocardiography estimate methods did not prove to be suitable in accurately measuring absolute cardiac output values but showed an excellent correlation with thermodilution method. Therefore, by using the measurement of cardiac output as supplemental data, echocardiography estimate methods can be used for detection and correction of hemodynamic disturbances during emergency and anesthesia in veterinary practice.

Simulation of Counting Efficiencies of Portable NaI Detector for Rapid Screening of Internal Exposure in Radiation Emergencies (방사선비상시 내부피폭 신속 분류를 위한 휴대용 NaI 검출기의 계측효율 전산모사)

  • Ha, Wi-Ho;Yoo, Jaeryong;Yoon, Seokwon;Pak, Min Jung;Kim, Jong Kyoung
    • Journal of Radiation Protection and Research
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    • v.40 no.4
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    • pp.211-215
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    • 2015
  • In case of radiation emergencies, radioactive materials released into environments can cause internal exposure of members of the public. Even though whole body counters are widely used for direct measurement of internally deposited radionuclides, those are not likely to be used at the field to rapidly screen internal exposure. In this study, we estimated the counting efficiencies of portable NaI detector for different size BOMAB phantoms using Monte Carlo transport code to apply handheld gamma spectrometers for rapid screening of internal exposure following radiological accidents. As a result of comparison for two counting geometries, counting efficiencies for sitting model were about 1.1 times higher than those for standing model. We found, however, that differences of counting efficiencies according to different size are higher than those according to counting geometry. Therefore, we concluded that when we assess internal exposure of small size people compared to the reference male, the body size should be considered to estimate more accurate radioactivity in the human body because counting efficiencies of 4-year old BOMAB phantom were about 2.4~3.1 times higher than those of reference male BOMAB phantom.

A Study on Depression in College Students (우울척도에 의한 대학생의 정신건강 평가)

  • Lee, Jong-Bum;Park, Byung-Tak;Cheung, Sung-Douk;Chung, Jong-Hak
    • Journal of Yeungnam Medical Science
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    • v.2 no.1
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    • pp.123-133
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    • 1985
  • The authors studied depression in 5,869 college students (male: 3,893, female: 1,976) using Zung's Self-Rating Depression Scale (SDS). The results are as follows: 1) Female college students showed significantly higher total depression scores than male college students (p<0.001). 2) The items of confusion, indecisiveness, and psychomotor retardation were scored higher in both groups and the Items of suicidal rumination, psychomotor agitation, constipation and tachycardia were scored lower in both groups. 3) 18.2% of male college students showed rather serious depression level of score 50 or higher, while 33.1 % of female college students showed the same scores. 4) The psychosocial factors relating to pessimistic views to past, present & future self images showed significantly high depression scores. 5) The depression items of fatigue, irritability, palpitation, hopelessness & dissatisfaction and the anxiety Items of fatigue, anxiousness, tachycardia, apprehension, fear, and body aches & pain were correlated significantly over 0.40 of correlation coefficient.

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Study on the Production and Management of Aquatic Animal : Application of ELISPOT-Assay for the Detection of Antibody Secreting Cells in Flounder, Paralichthys olivaceus (수산생물의 생산과 관리에 관한 기초연구 : ELISPOT 기법을 이용한 넙치의 항체생성 세포분석)

  • HA Jai Yi;PARK Jun-Hyo;KIM Myoung Sug;CHUNG Joon-Ki;JEONG Hyun Do
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.4
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    • pp.420-426
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    • 1999
  • We examined the immune response in flounder, Paralichthys olivaceus, with immunization of formalin killed Edwardsiella tarda as an antigen. The ELISPOT-assay (enzyme-linked immunospot assay) was optimized technically and applied to count the number of total and specific antibody secreting cells (TASC and SASC) in lymphocytes of different lymphatic organs. Incubation of lymphocytes on 96 well plate for more than 2.5hrs came out enough time in ELISPOT-assay for counting the antibody secreting cells in the anterior kidney and spleen. However, too much of plate-coated antigen or rabbit anti-flounder immunoglobulin for SASC or TASC counting, respectively, was appeared to decrease the sensitivity of the assay system. Specificity of the system was also confirmed by the absence of TASC in lymphocytes treated with cycloheximide to prevent protein synthesis. The peak numbers of SASC appeared at wk 3 post immunization after that there was a sharp decrease and reached to almost zero at wk 7. In the spleen and kidney, the timing and numbers of SASC on peak response were concurrent without preferential organ distribution. The specific antibody level in the sera increased rapidly between wk 2 and 3 after immunization, i.e. like the specific cellular response found with ELISPOT-assay on that period, However, the remained high level of specific serum antibody from wk 5 after immunization until the end of experiment was clearly distinguishable from the kinetics of SASC response decreased sharply.

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